Abstract：
:To describe the epidemiology of invasive Candida infection in a tertiary care paediatric hospital. Prospective single-centre survey on all Candida strains isolated from normally sterile fluids and urines in the period 2005-2015 . A total of 299 ICI were documented in 262 patients. Urinary tract infection represented the most frequent diagnosis (62%), followed by fungaemia (34%) and peritonitis (4%). Fungaemia was most frequent in children with cancer (59%) or in low birth weight neonates (61%), while urinary tract infections were more frequent in patients with urinary tract malformation. C.albicans was the most frequently isolated species (60%) compared with C. non-albicans, but differences were present according to the site of isolation and underlying conditions. Overall 90-day mortality was 7%, 13% in fungaemias, 8% in peritonitis and 2% in urinary tract infections. The rates of invasive Candida infection increased during the study period. Invasive Candida infection is diagnosed with increasing frequency in children. Site of isolation and aetiology are frequently related with the presence of underlying, favouring conditions. Mortality was not negligible, especially in the presence of more invasive infections and specific underlying conditions.
journal_name
Mycosesjournal_title
Mycosesauthors
Mesini A,Bandettini R,Caviglia I,Fioredda F,Amoroso L,Faraci M,Mattioli G,Piaggio G,Risso FM,Moscatelli A,Loy A,Castagnola Edoi
10.1111/myc.12570subject
Has Abstractpub_date
2017-02-01 00:00:00pages
118-123issue
2eissn
0933-7407issn
1439-0507journal_volume
60pub_type
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