Haematological parameters of alloxan-induced diabetic rats treated with leaf essential oil of Hoslundia opposita (Vahl).

abstract：:Unlike conventional materials that covalent bonds connecting atoms as the major force to hold the materials together, supramolecular biomaterials rely on noncovalent intermolecular interactions to assemble. The reversibility and biocompatibility of supramolecular biomaterials render them with diverse range of function...

journal_title：EXCLI journal

authors： Guo J,Tian C,Xu B

更新日期：2020-08-05 00:00:00

abstract：:Prosopis cineraria (L.) Druce (Leguminosae) (syn. Prosopis spicigera L.) has antidiabetic and antioxidant potential. Earlier we reported its hypolipidemic activity obtained from ethanol extract (ET-PCF). Object of this work was to isolate ferulic acid (FA) from ET-PCF and evaluate hypolipidemic activity against high-f...

journal_title：EXCLI journal

authors： Jain PG,Surana SJ

更新日期：2016-10-25 00:00:00

abstract：:The aim of this study was to evaluate the effect of acute and chronic physical and psychological stressors on the induction of oxidative stress in male rat liver. Male Wistar rats were randomly divided into 3 groups as following: control, physical and psychological stress groups. Stress was induced by communication bo...

journal_title：EXCLI journal

authors： Jafari M,Salehi M,Zardooz H,Rostamkhani F

更新日期：2014-02-24 00:00:00

abstract：:The relationship between leptin, insulin resistance and other hormonal parameters in polycystic ovarian syndrome (PCOS) is controversial. We investigated the effect of metformin on leptin levels in women with PCOS. Thirty women with PCOS received metformin 500 mg thrice a day. After two months of metformin treatment t...

journal_title：EXCLI journal

authors： Upadhyaya P,Rehan HS,Seth V

更新日期：2011-02-24 00:00:00

abstract：:This study was undertaken to determine whether exposure of operating room personnel to inhalation anesthetics, including nitrous oxide, isoflurane, and sevoflurane was associated with any hepatotoxic or nephrotoxic changes. Fifty-two operating room personnel and 52 non-exposed subjects were studied. A questionnaire pe...

journal_title：EXCLI journal

authors： Neghab M,Amiri F,Soleimani E,Yousefinejad S,Hassanzadeh J

更新日期：2020-03-25 00:00:00

abstract：:The aim of this study was the design and evaluation of a novel plasma stable, pH-sensitive niosomal formulation of Mitoxantrone by a modified ethanol injection method. Cholesterol hemisuccinate was added instead of cholesterol in order to produce pH-sensitivity property and using PEG-Poly (monomethyl itaconate)-CholC6...

journal_title：EXCLI journal

authors： Tila D,Yazdani-Arazi SN,Ghanbarzadeh S,Arami S,Pourmoazzen Z

更新日期：2015-01-06 00:00:00

abstract：:Previous studies proved the pro-angiogenic effect of Crocetin, a natural carotenoid dicarboxylic acid, in both in vivo and in vitro models. However, the exact mechanism of Crocetin action has not completely been elucidated yet. The current experiment was designed to find the activity of PI3K-Akt-eNOS axis after the tr...

journal_title：EXCLI journal

authors： Nasirzadeh M,Rasmi Y,Rahbarghazi R,Kheradmand F,Karimipour M,Aramwit P,Astinfeshan M,Gholinejad Z,Daeihasani B,Saboory E,Shirpoor A,Rezabakhsh A,Zolali E,Khalaji N

更新日期：2019-10-21 00:00:00

abstract：:Little is known about biogenically synthesized Zinc oxide nanoparticles (ZnONPs) from Isodon rugosus. Synthesis of metal oxide NPs from essential oil producing medicinal plants results in less harmful side effects to the human population as compared to chemically synthesized NPs. In this article, we report biogenic sy...

journal_title：EXCLI journal

authors： Siddiquah A,Hashmi SS,Mushtaq S,Renouard S,Blondeau JP,Abbasi R,Hano C,Abbasi BH

更新日期：2018-07-16 00:00:00

abstract：:This study aims to develop two alternate forms for Malay version of Auditory Verbal Learning Test (MAVLT) and to determine their equivalency and practice effect. Ninety healthy volunteers were subjected to the following neuropsychological tests at baseline, and at one month interval according to their assigned group; ...

journal_title：EXCLI journal

authors： Munjir N,Othman Z,Zakaria R,Shafin N,Hussain NA,Desa AM,Ahmad AH

更新日期：2015-07-07 00:00:00

abstract：:Considering the therapeutic values of bioflavonoids in colon cancer treatment, six 2'-hydroxy chalcones (C1-C6) were synthesized, characterized and screened for in vitro cytotoxicity on human colon carcinoma (HCT116) and African green monkey kidney epithelial cells (Vero). Only C5 showed selective cytotoxicity against...

journal_title：EXCLI journal

authors： Pande AN,Biswas S,Reddy ND,Jayashree BS,Kumar N,Rao CM

更新日期：2017-04-03 00:00:00

abstract：:Five Calligonum species endemic to the Tarim Basin - C. roborowskii, C. kuerlese, C. juoqiangense,C. yengisaricum, and C. taklimakanense - were compared using 14 morphological characteristics and nrDNA ITS and cpDNA trnL-F molecular data. Intraspecific and interspecific morphological variation was uncovered, with vari...

journal_title：EXCLI journal

authors： Abdurahman M,Sabirhazi G,Liu B,Yin L,Pan B

更新日期：2012-12-20 00:00:00

abstract：:Nanoencapsulation of drug/small molecules in nanocarriers (NCs) is a very promising approach for development of nanomedicine. Modern drug encapsulation methods allow efficient loading of drug molecules inside the NCs thereby reducing systemic toxicity associated with drugs. Targeting of NCs can enhance the accumulatio...

journal_title：EXCLI journal

authors： Kumari A,Singla R,Guliani A,Yadav SK

更新日期：2014-03-20 00:00:00

abstract：:One of the most fundamental operations in biological sequence analysis is multiple sequence alignment (MSA). The basic of multiple sequence alignment problems is to determine the most biologically plausible alignments of protein or DNA sequences. In this paper, an alignment method using genetic algorithm for multiple ...

journal_title：EXCLI journal

authors： Kumar M

更新日期：2015-12-15 00:00:00

abstract：:The liver is famous for its strong regenerative capacity, employing different modes of regeneration according to type and extent of injury. Mature liver cells are able to proliferate in order to replace the damaged tissue allowing the recovery of the parenchymal function. In more severe scenarios hepatocytes are belie...

journal_title：EXCLI journal

authors： Verhulst S,Best J,van Grunsven LA,Dollé L

更新日期：2015-01-06 00:00:00

abstract：:From both the structural and functional points of view, β-turns play important biological roles in proteins. In the present study, a novel two-stage hybrid procedure has been developed to identify β-turns in proteins. Binary logistic regression was initially used for the first time to select significant sequence param...

journal_title：EXCLI journal

authors： Asghari MP,Hayatshahi SH,Abdolmaleki P

更新日期：2012-07-05 00:00:00

abstract：:Fibroblast growth factor 21 (FGF21) is a major metabolic regulator that has been shown to be elevated in a number of metabolic disturbances including type 2 diabetes mellitus (T2DM) and the metabolic syndrome, but few studies about the relationship between serum FGF21 and the complications of diabetes have been done. ...

journal_title：EXCLI journal

authors： Mousavi Z,Bonakdaran S,Sahebkar A,Yaghoubi G,Yaghoubi MA,Davoudian N,Mohebbi M

更新日期：2017-11-22 00:00:00

abstract：:We present the case of a 77 year old male patient with metastatic pancreatic neuroendocrine tumor (NET). The patient was initially treated by extensive surgical resection that however, led to severe complications with delayed recovery. During follow-up, a number of new liver metastases were detected, one of which was ...

journal_title：EXCLI journal

authors： Ataeinia B,Loberg C,Kravets H,Beheshti M,von Mallek D,Mottaghy FM,Heinzel A

更新日期：2019-05-21 00:00:00

abstract：:Phoenix sylvestris (Arecaceae family) known as Indian Date Palm has been identified as a component of traditional medicine against various ailments. The present study was focused on phytochemical screening of crude hexane, dichloromethane and methanol leaf extracts. The crude extracts showed the presence of alkaloids,...

journal_title：EXCLI journal

authors： Sharma DC,Shukla R,Ali J,Sharma S,Bajpai P,Pathak N

更新日期：2016-02-05 00:00:00

abstract：:A series of phenyl-3-(thiophen-2-yl)-4, 5-dihydro-1H-pyrazole-1-carbothioamides (TTa-TTg) were synthesized by the ring closure reaction of phenyl-1-(thiophen-2-yl) prop-2-en-1-ones with thiosemicarbazide in alcoholic basic medium. All the final derivatives were evaluated for their antidepressant and neurotoxicity scre...

journal_title：EXCLI journal

authors： Mathew B,Suresh J,Anbazhagan S

更新日期：2014-04-29 00:00:00

abstract：:This review will concentrate on the clinical pharmacology, in particular pharmacodynamic data, related to atypical antipsychotics, clozapine, risperidone, paliperidone, olanzapine, que¬tiapine, amisulpride, ziprasidone, aripiprazole, asenapine, iloperidone, lurasidone and cariprazine. A summary of their acute pharmaco...

journal_title：EXCLI journal

authors： Mauri MC,Paletta S,Maffini M,Colasanti A,Dragogna F,Di Pace C,Altamura AC

更新日期：2014-10-13 00:00:00

abstract：:The aim of this study was to determine the effects of caffeine and chlorogenic acid supplementation on gut microbiota, and metabolic disturbances in patients with NAFLD and diabetes. In this randomized, placebo-controlled, clinical trial, 26 patients with diabetes and NAFLD were randomly assigned to four groups to rec...

journal_title：EXCLI journal

authors： Mansour A,Mohajeri-Tehrani MR,Karimi S,Sanginabadi M,Poustchi H,Enayati S,Asgarbeik S,Nasrollahzadeh J,Hekmatdoost A

更新日期：2020-03-02 00:00:00

abstract：:The essential oil obtained from leaves of Melissa officinalis L. (Family of Lamiaceae) growing in Algeria, was investigated for its chemical composition and in vitro antimicrobial activity. The chemical composition was determined by hydrodistillation and analyzed by GC/MS and GC-FID. Sixty-three compounds were identif...

journal_title：EXCLI journal

authors： Abdellatif F,Boudjella H,Zitouni A,Hassani A

更新日期：2014-07-17 00:00:00

abstract：:To date, a number of significant herbal drug interactions have their origins in the alteration of cytochrome P450 (CYP) activity by various phytochemicals. Among the most noteworthy are those involving St. John's wort and drugs metabolized by human CYP3A4 enzyme. This review article is the continued work from our prev...

journal_title：EXCLI journal

authors： Wanwimolruk S,Phopin K,Prachayasittikul V

更新日期：2014-08-20 00:00:00

abstract：:Lack of data on safety of herbal medicines have endangered human health and life. The present study evaluated the genotoxic and mutagenic effect of Kalanchoe laciniata to access the safety and usefulness of the medicinal plant. Aqua-methanolic and n-hexane extracts of K. laciniata were evaluated for the genotoxic pote...

journal_title：EXCLI journal

authors： Sharif A,Akhtar MF,Akhtar B,Saleem A,Manan M,Shabbir M,Ashraf M,Peerzada S,Ahmed S,Raza M

更新日期：2017-04-24 00:00:00

abstract：:To investigate whether offspring sex ratio at birth (SRB) was associated with maternal breast cancer risk, the present case-control study and a meta-analysis of literature were done. A total of 389 female breast cancer patients who had at least one offspring participated in the study. From general population 356 healt...

journal_title：EXCLI journal

authors： Saadat M

更新日期：2010-07-26 00:00:00

abstract：:Pharmaceutical effluents contain toxic xenobiotics capable of contaminating aquatic environments. Untreated effluents are illegally discharged into aquatic environment in most developing countries. Pharmaceutical effluent induced alterations in biomarkers of genetic and systemic damage on rodents. However, information...

journal_title：EXCLI journal

authors： Alimba CG,Adekoya KO,Soyinka OO

更新日期：2019-02-06 00:00:00

abstract：:Spontaneous eye-blinks occur much more often than it would be necessary to maintain the tear film on the eyes. Various factors like cognitive demand, task engagement, or fatigue are influencing spontaneous blink rate. During cognitive information processing there is evidence that blinks occur preferably at moments tha...

journal_title：EXCLI journal

authors： Wascher E,Heppner H,Möckel T,Kobald SO,Getzmann S

更新日期：2015-11-27 00:00:00

abstract：:Toxoplasma gondii is a common protozoan parasite, which infects warm-blooded mammals, including mice and humans, throughout the world. The negative effects of T. gondii infection on the human reproductive system have been documented, especially in females. However, only few studies have examined the effects of T. gond...

journal_title：EXCLI journal

authors： Saki J,Sabaghan M,Arjmand R,Teimoori A,Rashno M,Saki G,Shojaee S

更新日期：2020-08-24 00:00:00

abstract：:The present study is conducted to determine the potential mechanisms of Boron compounds, boric acid (BA) and borax (BX), on genotoxicity of zebrafish Danio rerio for 24, 48, 72 and 96-hours acute exposure (level:1, 4, 16, 64 mg/l BA and BX) in semi-static bioassay experiment. For that purpose, peripheral erythrocytes ...

journal_title：EXCLI journal

authors： Gülsoy N,Yavas C,Mutlu Ö

更新日期：2015-07-30 00:00:00

abstract：:There are abundant studies indicating that blocking gap junctions (GJs) containing connexin 36 (Cx36) inhibit seizures. However, recent evidences demonstrate proconvulsant effect of such intervention. Electrical coupling between GABAergic interneurons in CA1 region of hippocampus is mediated through Cx36 GJs. We inves...

journal_title：EXCLI journal

authors： Ghanbarabadi JK,Sayyah M

更新日期：2013-03-14 00:00:00