The relationship between serum levels of fibroblast growth factor 21 and diabetic retinopathy.

abstract：:The traditional uses of Portulaca oleracea L. (PO) with anti-inflammatory and anti-cancer activity as well as antioxidants properties were expressed previously. Glioma is considered the most common primary brain tumor and its malignant form is the most lethal adult brain tumor, that glioblastoma covers about 50 % of g...

journal_title：EXCLI journal

authors： Baradaran Rahimi V,Mousavi SH,Haghighi S,Soheili-Far S,Askari VR

更新日期：2019-03-20 00:00:00

abstract：:Recently, bioinformatics has advanced to the level that it allows almost accurate prediction of molecular interactions that hold together a protein and a ligand in the bound state. For instance, the program AutoDock has been developed to provide a procedure for predicting the interaction of small molecules with macrom...

journal_title：EXCLI journal

authors： Rizvi SM,Shakil S,Haneef M

更新日期：2013-09-23 00:00:00

abstract：:A reliable biomarker has not been identified to predict the outcome of traumatic brain injury (TBI) in children. Therefore, the present systematic review and meta-analysis aimed to assess the association between neuron specific enolase (NSE) and traumatic brain injury (TBI) in children. Two independent reviewers searc...

journal_title：EXCLI journal

authors： Nakhjavan-Shahraki B,Yousefifard M,Oraii A,Sarveazad A,Hosseini M

更新日期：2017-07-03 00:00:00

abstract：:Patients with diabetes tend to have an increased risk of osteoporosis that may be related to hyperglycemia. In vitro evidence has shown that high glucose can affect the proliferation and osteogenic differentiation of mesenchymal stem cells (MSCs). Tissue regeneration depends mainly on MSCs. However, the exact mechanis...

journal_title：EXCLI journal

authors： Wang J,Wang B,Li Y,Wang D,Lingling E,Bai Y,Liu H

更新日期：2013-06-27 00:00:00

abstract：:Achillea eriophora (Asteraceae) is a medicinal plant commonly used in Iran. This study was performed to determine the cardiovascular effects of hydroethanolic extract of A. eriophora (HEAE) and the underlying mechanisms in anaesthetized rats. The acute effects of intravenous (i.v.) administration of different doses of...

journal_title：EXCLI journal

authors： Anvari S,Bahaoddini A,Moein M,Khosravi AR

更新日期：2016-12-07 00:00:00

abstract：INTRODUCTION:Hypovitaminosis D is reported to be associated with several medical complications. Recent studies have reported a high worldwide prevalence of Vitamin D deficiency in the general population (up to 80 %). This is even higher in patients with chronic kidney disease (CKD) and increases with advancing stages o...

journal_title：EXCLI journal

authors： Rozita M,Noorul Afidza M,Ruslinda M,Cader R,Halim AG,Kong CT,Nor Azmi K,Shah SA

更新日期：2013-06-11 00:00:00

abstract：:Stevens-Johnson syndrome (SJS) is an immune mediated hypersensitivity reaction. Significant involvement of oral, nasal, eye, vaginal, urethral, GI and lower respiratory tract mucous membrane may develop. It is usually a reaction due to a medication or due to an infection. In 95 % of case reports, drugs were found to b...

journal_title：EXCLI journal

authors： Zaidi M,Zaidi SK,Bhutto M,Umer MY

更新日期：2017-05-18 00:00:00

abstract：:An enzyme-coupled colorimetric assay for quantification of urinary sarcosine was developed. The proposed method is a specific reaction based on hydrogen peroxide (H2O2) formation via sarcosine oxidase (SOX). The liberated H2O2 reacts with Amplex Red in the presence of horseradish peroxidase (HRP) to produce the red-fl...

journal_title：EXCLI journal

authors： Yamkamon V,Phakdee B,Yainoy S,Suksrichawalit T,Tatanandana T,Sangkum P,Eiamphungporn W

更新日期：2018-05-17 00:00:00

abstract：:Little is known about biogenically synthesized Zinc oxide nanoparticles (ZnONPs) from Isodon rugosus. Synthesis of metal oxide NPs from essential oil producing medicinal plants results in less harmful side effects to the human population as compared to chemically synthesized NPs. In this article, we report biogenic sy...

journal_title：EXCLI journal

authors： Siddiquah A,Hashmi SS,Mushtaq S,Renouard S,Blondeau JP,Abbasi R,Hano C,Abbasi BH

更新日期：2018-07-16 00:00:00

abstract：:Corn cob is a major component of agricultural and domestic waste in many parts of the world. It is composed mainly of cellulose which can be converted to energy in form of bioethanol as an efficient and effective means of waste management. Production of cellulolytic enzymes were induced in the fungi Aspergillus niger ...

journal_title：EXCLI journal

authors： Saliu BK,Sani A

更新日期：2012-08-15 00:00:00

abstract：:Octyl gallate (OG) is an antioxidant commonly used in food, although there is no definition of its acceptable daily intake. There are reports in vitro and in vivo showing that food additives and drugs can alter lipid metabolism. Lipid droplet accumulation in hepatic cells is one of the main findings in the unregulated...

journal_title：EXCLI journal

authors： Lima KG,Schneider Levorse VG,Rosa Garcia MC,de Souza Basso B,Pasqualotto Costa B,Antunes GL,Luft C,Haute GV,Leal Xavier L,Donadio MVF,Rodrigues de Oliveira J

更新日期：2020-07-06 00:00:00

abstract：:Numerous studies have demonstrated the robustness of the framing effect in a variety of contexts, especially in medical decision making. Unfortunately, research is still inconsistent as to how so many variables impact framing effects in medical decision making. Additionally, much attention should be paid to the framin...

journal_title：EXCLI journal

authors： Gong J,Zhang Y,Feng J,Huang Y,Wei Y,Zhang W

更新日期：2013-01-18 00:00:00

abstract：:Sleep deprivation affects all aspects of health. Adverse health effects by sleep deviation are still underestimated and undervalued in clinical practice and, to a much greater extent in monitoring human health. We hypothesized that sleep deprivation-induced mild organ injuries; oxidative stress and inflammation might ...

journal_title：EXCLI journal

authors： Periasamy S,Hsu DZ,Fu YH,Liu MY

更新日期：2015-05-18 00:00:00

abstract：:Aromatase is a rate-limiting enzyme for estrogen biosynthesis that is overproduced in breast cancer tissue. To block the growth of breast tumors, aromatase inhibitors (AIs) are employed to bind and inhibit aromatase in order to lower the amount of estrogen produced in the body. Although a number of synthetic aromatase...

journal_title：EXCLI journal

authors： Shoombuatong W,Schaduangrat N,Nantasenamat C

更新日期：2018-07-20 00:00:00

abstract：:Renin Angiotensin Aldosterone System (RAAS) plays an important role in the development of hypertension. On the other hand, hypertension is a well-known and independent risk factor for cognitive impairment. The aim of the present study was to evaluate the relationship of blood pressure control, plasma angiotensin pepti...

journal_title：EXCLI journal

authors： Sen S,Gürel N,Ufuktepe B,Özünal ZG,Büyüklü Ç,Üresin Y

更新日期：2017-03-10 00:00:00

abstract：:Curcuminoids are dietary complexes extracted from the seeds of Curcuma longa L. that contain curcumin, bisdemethoxycurcumin and desmethoxycurcumin. Curcuminoids are popular for their pleiotropic therapeutic functions, such as their anti-inflammatory and anti-oxidant effects. Nonetheless, their clinical use is associat...

journal_title：EXCLI journal

authors： Yousefi F,Lavi Arab F,Jaafari MR,Rastin M,Tabasi N,Hatamipour M,Nikkhah K,Mahmoudi M

更新日期：2019-06-17 00:00:00

abstract：:The liver is famous for its strong regenerative capacity, employing different modes of regeneration according to type and extent of injury. Mature liver cells are able to proliferate in order to replace the damaged tissue allowing the recovery of the parenchymal function. In more severe scenarios hepatocytes are belie...

journal_title：EXCLI journal

authors： Verhulst S,Best J,van Grunsven LA,Dollé L

更新日期：2015-01-06 00:00:00

abstract：:Ursolic acid (UA) is a pentacyclic triterpenoid carboxylic acid that is found in plants and herbal products. It is one of the chemopreventive agents, which can suppress cancer cell proliferation and induce apoptosis. UA possesses various biological activities including anticancer, anti-inflammatory, anti-oxidative and...

journal_title：EXCLI journal

authors： Kaewthawee N,Brimson S

更新日期：2013-02-08 00:00:00

abstract：:Prosopis cineraria (L.) Druce (Leguminosae) (syn. Prosopis spicigera L.) has antidiabetic and antioxidant potential. Earlier we reported its hypolipidemic activity obtained from ethanol extract (ET-PCF). Object of this work was to isolate ferulic acid (FA) from ET-PCF and evaluate hypolipidemic activity against high-f...

journal_title：EXCLI journal

authors： Jain PG,Surana SJ

更新日期：2016-10-25 00:00:00

abstract：:Previous studies proved the pro-angiogenic effect of Crocetin, a natural carotenoid dicarboxylic acid, in both in vivo and in vitro models. However, the exact mechanism of Crocetin action has not completely been elucidated yet. The current experiment was designed to find the activity of PI3K-Akt-eNOS axis after the tr...

journal_title：EXCLI journal

authors： Nasirzadeh M,Rasmi Y,Rahbarghazi R,Kheradmand F,Karimipour M,Aramwit P,Astinfeshan M,Gholinejad Z,Daeihasani B,Saboory E,Shirpoor A,Rezabakhsh A,Zolali E,Khalaji N

更新日期：2019-10-21 00:00:00

abstract：:A series of phenyl-3-(thiophen-2-yl)-4, 5-dihydro-1H-pyrazole-1-carbothioamides (TTa-TTg) were synthesized by the ring closure reaction of phenyl-1-(thiophen-2-yl) prop-2-en-1-ones with thiosemicarbazide in alcoholic basic medium. All the final derivatives were evaluated for their antidepressant and neurotoxicity scre...

journal_title：EXCLI journal

authors： Mathew B,Suresh J,Anbazhagan S

更新日期：2014-04-29 00:00:00

abstract：:Spontaneous eye-blinks occur much more often than it would be necessary to maintain the tear film on the eyes. Various factors like cognitive demand, task engagement, or fatigue are influencing spontaneous blink rate. During cognitive information processing there is evidence that blinks occur preferably at moments tha...

journal_title：EXCLI journal

authors： Wascher E,Heppner H,Möckel T,Kobald SO,Getzmann S

更新日期：2015-11-27 00:00:00

abstract：:From both the structural and functional points of view, β-turns play important biological roles in proteins. In the present study, a novel two-stage hybrid procedure has been developed to identify β-turns in proteins. Binary logistic regression was initially used for the first time to select significant sequence param...

journal_title：EXCLI journal

authors： Asghari MP,Hayatshahi SH,Abdolmaleki P

更新日期：2012-07-05 00:00:00

abstract：:Unlike conventional materials that covalent bonds connecting atoms as the major force to hold the materials together, supramolecular biomaterials rely on noncovalent intermolecular interactions to assemble. The reversibility and biocompatibility of supramolecular biomaterials render them with diverse range of function...

journal_title：EXCLI journal

authors： Guo J,Tian C,Xu B

更新日期：2020-08-05 00:00:00

abstract：:Our experimental work was aimed at evaluating the safety and protective effects of dietary spirulina supplementation on the kidney of newborn rats, the offspring of lead contaminated lactating mothers. Female rats were randomly divided into four groups: group I (control) was given a normal diet, group II (positive con...

journal_title：EXCLI journal

authors： Gargouri M,Soussi A,Akrouti A,Magné C,El Feki A

更新日期：2018-03-02 00:00:00

abstract：:Vitamin D deficiency, common in the population with irritable bowel syndrome (IBS), can induce the main factors that lead to IBS clinical symptoms, such as depression, anxiety, and inflammation. Serotonin (5-HT) plays an important role in the pathophysiology of IBS, and its production and secretion are increased from ...

journal_title：EXCLI journal

authors： Khalighi Sikaroudi M,Mokhtare M,Shidfar F,Janani L,Faghihi Kashani A,Masoodi M,Agah S,Dehnad A,Shidfar S

更新日期：2020-05-19 00:00:00

abstract：:The present study is conducted to determine the potential mechanisms of Boron compounds, boric acid (BA) and borax (BX), on genotoxicity of zebrafish Danio rerio for 24, 48, 72 and 96-hours acute exposure (level:1, 4, 16, 64 mg/l BA and BX) in semi-static bioassay experiment. For that purpose, peripheral erythrocytes ...

journal_title：EXCLI journal

authors： Gülsoy N,Yavas C,Mutlu Ö

更新日期：2015-07-30 00:00:00

abstract：:Experimentally-induced total sleep deprivation (TSD) and chronic partial sleep restriction (CPSR) leads to the emergence of cognitive impairments. This is hypothesized to result from a consequent neuroinflammation which may also hasten the neurodegenerative processes. Neuroinflammatory markers such as tumor necrosis f...

journal_title：EXCLI journal

authors： Torabi-Nami M,Nasehi M,Zarrindast MR

更新日期：2013-04-14 00:00:00

abstract：:Nanoencapsulation of drug/small molecules in nanocarriers (NCs) is a very promising approach for development of nanomedicine. Modern drug encapsulation methods allow efficient loading of drug molecules inside the NCs thereby reducing systemic toxicity associated with drugs. Targeting of NCs can enhance the accumulatio...

journal_title：EXCLI journal

authors： Kumari A,Singla R,Guliani A,Yadav SK

更新日期：2014-03-20 00:00:00

abstract：:This study was undertaken to determine whether exposure of operating room personnel to inhalation anesthetics, including nitrous oxide, isoflurane, and sevoflurane was associated with any hepatotoxic or nephrotoxic changes. Fifty-two operating room personnel and 52 non-exposed subjects were studied. A questionnaire pe...

journal_title：EXCLI journal

authors： Neghab M,Amiri F,Soleimani E,Yousefinejad S,Hassanzadeh J

更新日期：2020-03-25 00:00:00