Offspring sex ratio at birth and maternal breast cancer risk: A case-control study and meta-analysis of literature.

abstract：:Pharmaceutical effluents contain toxic xenobiotics capable of contaminating aquatic environments. Untreated effluents are illegally discharged into aquatic environment in most developing countries. Pharmaceutical effluent induced alterations in biomarkers of genetic and systemic damage on rodents. However, information...

journal_title：EXCLI journal

authors： Alimba CG,Adekoya KO,Soyinka OO

更新日期：2019-02-06 00:00:00

abstract：:Dibutyltin dichloride (DBTC) is an organotin compound used as model for acute and chronic pancreatitis. Oxidative stress is one of the mechanisms of propagation of acinar cell injury in acute pancreatitis. Selenium is an essential cofactor in the antioxidant glutathione peroxidase pathway. Selenium levels are describe...

journal_title：EXCLI journal

authors： Merkord J,Görl N,Lemke M,Berg A,Weber H,Ramer R,Hennighausen G

更新日期：2017-02-16 00:00:00

abstract：:The chemical composition of the essential oils of different Allium nigrum L. organs and the antibacterial activity were evaluated. The study is particularly interesting because hitherto there are no reports on the antibacterial screening of this species with specific chemical composition. Therefore, essential oils fro...

journal_title：EXCLI journal

authors： Rouis-Soussi LS,Ayeb-Zakhama AE,Mahjoub A,Flamini G,Jannet HB,Harzallah-Skhiri F

更新日期：2014-05-13 00:00:00

abstract：:Stevens-Johnson syndrome (SJS) is an immune mediated hypersensitivity reaction. Significant involvement of oral, nasal, eye, vaginal, urethral, GI and lower respiratory tract mucous membrane may develop. It is usually a reaction due to a medication or due to an infection. In 95 % of case reports, drugs were found to b...

journal_title：EXCLI journal

authors： Zaidi M,Zaidi SK,Bhutto M,Umer MY

更新日期：2017-05-18 00:00:00

abstract：:Unlike conventional materials that covalent bonds connecting atoms as the major force to hold the materials together, supramolecular biomaterials rely on noncovalent intermolecular interactions to assemble. The reversibility and biocompatibility of supramolecular biomaterials render them with diverse range of function...

journal_title：EXCLI journal

authors： Guo J,Tian C,Xu B

更新日期：2020-08-05 00:00:00

abstract：:Phoenix sylvestris (Arecaceae family) known as Indian Date Palm has been identified as a component of traditional medicine against various ailments. The present study was focused on phytochemical screening of crude hexane, dichloromethane and methanol leaf extracts. The crude extracts showed the presence of alkaloids,...

journal_title：EXCLI journal

authors： Sharma DC,Shukla R,Ali J,Sharma S,Bajpai P,Pathak N

更新日期：2016-02-05 00:00:00

abstract：:Everolimus (EVR), as a rapamycin analog, is a selective inhibitor of the mammalian target of rapamycin (mTOR) kinase and its associated signaling pathway. mTOR is a serine/threonine protein kinase and its hyperactivity is involved in the pathophysiology of Alzheimer's disease (AD) and associated cognitive deficits. Th...

journal_title：EXCLI journal

authors： Fanoudi S,Hosseini M,Alavi MS,Boroushaki MT,Hosseini A,Sadeghnia HR

更新日期：2018-10-29 00:00:00

abstract：:Nephropathy associated with type 2 diabetes is the single most common cause of end-stage renal disease. The aim of the present study was to evaluate the preventive effect of ethanolic extract of Embelia ribes fruit (EER) against high fat diet (HFD) and low dose streptozotocin (STZ)-induced diabetic nephrotoxicity in W...

journal_title：EXCLI journal

authors： Chaudhari HS,Bhandari U,Khanna G

更新日期：2013-09-24 00:00:00

abstract：:Previous studies proved the pro-angiogenic effect of Crocetin, a natural carotenoid dicarboxylic acid, in both in vivo and in vitro models. However, the exact mechanism of Crocetin action has not completely been elucidated yet. The current experiment was designed to find the activity of PI3K-Akt-eNOS axis after the tr...

journal_title：EXCLI journal

authors： Nasirzadeh M,Rasmi Y,Rahbarghazi R,Kheradmand F,Karimipour M,Aramwit P,Astinfeshan M,Gholinejad Z,Daeihasani B,Saboory E,Shirpoor A,Rezabakhsh A,Zolali E,Khalaji N

更新日期：2019-10-21 00:00:00

abstract：:Recently, bioinformatics has advanced to the level that it allows almost accurate prediction of molecular interactions that hold together a protein and a ligand in the bound state. For instance, the program AutoDock has been developed to provide a procedure for predicting the interaction of small molecules with macrom...

journal_title：EXCLI journal

authors： Rizvi SM,Shakil S,Haneef M

更新日期：2013-09-23 00:00:00

abstract：:Nanoencapsulation of drug/small molecules in nanocarriers (NCs) is a very promising approach for development of nanomedicine. Modern drug encapsulation methods allow efficient loading of drug molecules inside the NCs thereby reducing systemic toxicity associated with drugs. Targeting of NCs can enhance the accumulatio...

journal_title：EXCLI journal

authors： Kumari A,Singla R,Guliani A,Yadav SK

更新日期：2014-03-20 00:00:00

abstract：:Serum concentration of lipids and lipoproteins changes during the course of acute coronary syndrome as a consequence of the inflammatory response. The objective of this study was to evaluate the effect of acute myocardial infarction (AMI) on the levels of lipid profile and inflammatory markers. We investigated 400 pat...

journal_title：EXCLI journal

authors： Shrivastava AK,Singh HV,Raizada A,Singh SK

更新日期：2015-04-10 00:00:00

abstract：:Morphological identification is a widespread procedure to assess the presence of apoptosis by visual inspection of the morphological characteristics or the fluorescence images. The procedure is lengthy and results are observer dependent. A quantitative automatic analysis is objective and would greatly help the routine...

journal_title：EXCLI journal

authors： Liu Y,Lin W,Yang X,Liang W,Zhang J,Meng M,Rice JR,Sa Y,Feng Y

更新日期：2014-01-29 00:00:00

abstract：:The liver is famous for its strong regenerative capacity, employing different modes of regeneration according to type and extent of injury. Mature liver cells are able to proliferate in order to replace the damaged tissue allowing the recovery of the parenchymal function. In more severe scenarios hepatocytes are belie...

journal_title：EXCLI journal

authors： Verhulst S,Best J,van Grunsven LA,Dollé L

更新日期：2015-01-06 00:00:00

abstract：:Prosopis cineraria (L.) Druce (Leguminosae) (syn. Prosopis spicigera L.) has antidiabetic and antioxidant potential. Earlier we reported its hypolipidemic activity obtained from ethanol extract (ET-PCF). Object of this work was to isolate ferulic acid (FA) from ET-PCF and evaluate hypolipidemic activity against high-f...

journal_title：EXCLI journal

authors： Jain PG,Surana SJ

更新日期：2016-10-25 00:00:00

abstract：:Curcuminoids are dietary complexes extracted from the seeds of Curcuma longa L. that contain curcumin, bisdemethoxycurcumin and desmethoxycurcumin. Curcuminoids are popular for their pleiotropic therapeutic functions, such as their anti-inflammatory and anti-oxidant effects. Nonetheless, their clinical use is associat...

journal_title：EXCLI journal

authors： Yousefi F,Lavi Arab F,Jaafari MR,Rastin M,Tabasi N,Hatamipour M,Nikkhah K,Mahmoudi M

更新日期：2019-06-17 00:00:00

abstract：:Experimentally-induced total sleep deprivation (TSD) and chronic partial sleep restriction (CPSR) leads to the emergence of cognitive impairments. This is hypothesized to result from a consequent neuroinflammation which may also hasten the neurodegenerative processes. Neuroinflammatory markers such as tumor necrosis f...

journal_title：EXCLI journal

authors： Torabi-Nami M,Nasehi M,Zarrindast MR

更新日期：2013-04-14 00:00:00

abstract：:A reliable biomarker has not been identified to predict the outcome of traumatic brain injury (TBI) in children. Therefore, the present systematic review and meta-analysis aimed to assess the association between neuron specific enolase (NSE) and traumatic brain injury (TBI) in children. Two independent reviewers searc...

journal_title：EXCLI journal

authors： Nakhjavan-Shahraki B,Yousefifard M,Oraii A,Sarveazad A,Hosseini M

更新日期：2017-07-03 00:00:00

abstract：:Activation of the hypoxia-inducible factor (HIF)-pathway in hepatocellular carcinoma (HCC) induces therapy resistant tumours, characterized by increased liver progenitor cell (LPCs) characteristics and poor prognosis. We previously reported corresponding results in mice with HCC in which hypoxia was mimicked by prolyl...

journal_title：EXCLI journal

authors： Bogaerts E,Paridaens A,Verhelst X,Carmeliet P,Geerts A,Van Vlierberghe H,Devisscher L

更新日期：2016-11-11 00:00:00

abstract：:Metabolic syndrome (MS) is a condition associated with metabolic abnormalities that are characterized by central obesity (e.g. waist circumference or body mass index), hypertension (e.g. systolic or diastolic blood pressure), hyperglycemia (e.g. fasting plasma glucose) and dyslipidemia (e.g. triglyceride and high-dens...

journal_title：EXCLI journal

authors： Worachartcheewan A,Schaduangrat N,Prachayasittikul V,Nantasenamat C

更新日期：2018-01-10 00:00:00

abstract：:Vitamin D deficiency, common in the population with irritable bowel syndrome (IBS), can induce the main factors that lead to IBS clinical symptoms, such as depression, anxiety, and inflammation. Serotonin (5-HT) plays an important role in the pathophysiology of IBS, and its production and secretion are increased from ...

journal_title：EXCLI journal

authors： Khalighi Sikaroudi M,Mokhtare M,Shidfar F,Janani L,Faghihi Kashani A,Masoodi M,Agah S,Dehnad A,Shidfar S

更新日期：2020-05-19 00:00:00

abstract：:Recently, many articles have reported different levels and distribution of amphetamine hitherto detected in biological fluids now appreciably found in aquatic environment at ng/L levels. Identification and measurement of amphetamine and its metabolites in surface and sewage waters using higher performance liquid chrom...

journal_title：EXCLI journal

authors： Mustapha AO,Ajao UL

更新日期：2011-08-19 00:00:00

abstract：:Fibroblast growth factor 21 (FGF21) is a major metabolic regulator that has been shown to be elevated in a number of metabolic disturbances including type 2 diabetes mellitus (T2DM) and the metabolic syndrome, but few studies about the relationship between serum FGF21 and the complications of diabetes have been done. ...

journal_title：EXCLI journal

authors： Mousavi Z,Bonakdaran S,Sahebkar A,Yaghoubi G,Yaghoubi MA,Davoudian N,Mohebbi M

更新日期：2017-11-22 00:00:00

abstract：:Five Calligonum species endemic to the Tarim Basin - C. roborowskii, C. kuerlese, C. juoqiangense,C. yengisaricum, and C. taklimakanense - were compared using 14 morphological characteristics and nrDNA ITS and cpDNA trnL-F molecular data. Intraspecific and interspecific morphological variation was uncovered, with vari...

journal_title：EXCLI journal

authors： Abdurahman M,Sabirhazi G,Liu B,Yin L,Pan B

更新日期：2012-12-20 00:00:00

abstract：:Oxidative stress is the common underlying mechanism of damage in ischemic stroke. Therefore, we aimed to evaluate the possible protective effects of polyhydroxylated fullerene derivatives on brain infarction and oxidative/nitrosative stress in a rat model of ischemic stroke. The experiment was performed by four groups...

journal_title：EXCLI journal

authors： Vani JR,Mohammadi MT,Foroshani MS,Jafari M

更新日期：2016-06-20 00:00:00

abstract：:A series of phenyl-3-(thiophen-2-yl)-4, 5-dihydro-1H-pyrazole-1-carbothioamides (TTa-TTg) were synthesized by the ring closure reaction of phenyl-1-(thiophen-2-yl) prop-2-en-1-ones with thiosemicarbazide in alcoholic basic medium. All the final derivatives were evaluated for their antidepressant and neurotoxicity scre...

journal_title：EXCLI journal

authors： Mathew B,Suresh J,Anbazhagan S

更新日期：2014-04-29 00:00:00

abstract：:Previous research has shown the beneficial effects of aqueous extract of Piper sarmentosum (P.s) on atherosclerosis. The first stage in atherosclerosis is the formation of foam cell. The aim of this study was to investigate the effect of the methanol extract of P.s on fatty streaks by calculating neointimal foam cell ...

journal_title：EXCLI journal

authors： Amran AA,Zakaria Z,Othman F,Das S,Al-Mekhlafi HM,Raj S,Nordin NA

更新日期：2012-06-15 00:00:00

abstract：:Considering the therapeutic values of bioflavonoids in colon cancer treatment, six 2'-hydroxy chalcones (C1-C6) were synthesized, characterized and screened for in vitro cytotoxicity on human colon carcinoma (HCT116) and African green monkey kidney epithelial cells (Vero). Only C5 showed selective cytotoxicity against...

journal_title：EXCLI journal

authors： Pande AN,Biswas S,Reddy ND,Jayashree BS,Kumar N,Rao CM

更新日期：2017-04-03 00:00:00

abstract：:DNA and chromosomal damage in peripheral blood leukocytes of patients with coronary artery disease (CAD) were investigated by using the single cell gel electrophoresis assay /comet and cytokinesis- block micronucleus (CBMN) assays, respectively. The case-control study comprised patients with CAD (n = 46; average age 5...

journal_title：EXCLI journal

authors： Bhat MA,Mahajan N,Gandhi G

更新日期：2013-10-08 00:00:00

abstract：:This review will concentrate on the clinical pharmacology, in particular pharmacodynamic data, related to atypical antipsychotics, clozapine, risperidone, paliperidone, olanzapine, que¬tiapine, amisulpride, ziprasidone, aripiprazole, asenapine, iloperidone, lurasidone and cariprazine. A summary of their acute pharmaco...

journal_title：EXCLI journal

authors： Mauri MC,Paletta S,Maffini M,Colasanti A,Dragogna F,Di Pace C,Altamura AC

更新日期：2014-10-13 00:00:00