Abstract:
:Recently, many articles have reported different levels and distribution of amphetamine hitherto detected in biological fluids now appreciably found in aquatic environment at ng/L levels. Identification and measurement of amphetamine and its metabolites in surface and sewage waters using higher performance liquid chromatographic methodologies in the literatures now on current trend have provided information that are of scientific interest and effectively replaced immunological methods which only suggest the presence of these substances. Active research on both distribution and impacts of this important drug of abuse and related metabolites in the wastewaters are on-going.
journal_name
EXCLI Jjournal_title
EXCLI journalauthors
Mustapha AO,Ajao ULsubject
Has Abstractpub_date
2011-08-19 00:00:00pages
140-148issn
1611-2156journal_volume
10pub_type
杂志文章相关文献
EXCLI Journal文献大全abstract::Octyl gallate (OG) is an antioxidant commonly used in food, although there is no definition of its acceptable daily intake. There are reports in vitro and in vivo showing that food additives and drugs can alter lipid metabolism. Lipid droplet accumulation in hepatic cells is one of the main findings in the unregulated...
journal_title:EXCLI journal
pub_type: 杂志文章
doi:10.17179/excli2020-2214
更新日期:2020-07-06 00:00:00
abstract::Hepatocellular carcinoma or Liver cancer (LC) is the sixth most common cancer and the fourth cause of death worldwide in 2018. There has not been a comprehensive study on the survival rate of patients with LC in Asia yet. Therefore, the present study was conducted to evaluate the survival rate of patients with LC in A...
journal_title:EXCLI journal
pub_type: 杂志文章,评审
doi:10.17179/excli2019-1842
更新日期:2020-01-13 00:00:00
abstract::Exposure to microgravity leads to orthostatic intolerance in astronauts and differential vascular structural and functional adaptations have been implicated in its occurrence. The present study tended to clarify the characteristics of vascular inflammation and oxidative stress in hindlimb unweighting (HU) rat vasculat...
journal_title:EXCLI journal
pub_type: 杂志文章
doi:
更新日期:2010-12-23 00:00:00
abstract::The aim of this study is to investigate the mechanism of electro-acupuncture (EA) on the recovery of injured spinal cord. Rats were randomly divided into normal control, sham-operated, SCI, SCI+EA group and T10 segment spinal cord injury (SCI) rat model was established by the modified Allen's method. After 7 days, the...
journal_title:EXCLI journal
pub_type: 杂志文章
doi:10.17179/excli2017-123
更新日期:2017-03-23 00:00:00
abstract::Recently, bioinformatics has advanced to the level that it allows almost accurate prediction of molecular interactions that hold together a protein and a ligand in the bound state. For instance, the program AutoDock has been developed to provide a procedure for predicting the interaction of small molecules with macrom...
journal_title:EXCLI journal
pub_type: 杂志文章
doi:
更新日期:2013-09-23 00:00:00
abstract::Previous research has shown the beneficial effects of aqueous extract of Piper sarmentosum (P.s) on atherosclerosis. The first stage in atherosclerosis is the formation of foam cell. The aim of this study was to investigate the effect of the methanol extract of P.s on fatty streaks by calculating neointimal foam cell ...
journal_title:EXCLI journal
pub_type: 杂志文章
doi:
更新日期:2012-06-15 00:00:00
abstract::Curcuminoids are dietary complexes extracted from the seeds of Curcuma longa L. that contain curcumin, bisdemethoxycurcumin and desmethoxycurcumin. Curcuminoids are popular for their pleiotropic therapeutic functions, such as their anti-inflammatory and anti-oxidant effects. Nonetheless, their clinical use is associat...
journal_title:EXCLI journal
pub_type: 杂志文章
doi:10.17179/excli2019-1366
更新日期:2019-06-17 00:00:00
abstract::Hematopoietic stem cells (HSCs) form a rare population of multipotent stem cells, which give rise to all hematopoietic lineages. HSCs home to bone marrow niches and circulate between blood and bone marrow. Many factors, especially SDF1a, affect the circulation of HSCs, but these have not been fully recognized. SDF1a h...
journal_title:EXCLI journal
pub_type: 杂志文章,评审
doi:10.17179/excli2014-585
更新日期:2016-02-15 00:00:00
abstract::To our knowledge, in spite of several trials exploring the beneficial effect of n-3 polyunsaturated fatty acids (PUFA) on polycystic ovary syndrome (PCOS), no comprehensive evidence has investigated the effects of n-3 PUFA consumption on PCOS complications. Therefore, our aim was to conduct a review to investigate the...
journal_title:EXCLI journal
pub_type: 杂志文章,评审
doi:10.17179/excli2019-1534
更新日期:2019-07-25 00:00:00
abstract::The aim of this study was to evaluate the effect of acute and chronic physical and psychological stressors on the induction of oxidative stress in male rat liver. Male Wistar rats were randomly divided into 3 groups as following: control, physical and psychological stress groups. Stress was induced by communication bo...
journal_title:EXCLI journal
pub_type: 杂志文章
doi:
更新日期:2014-02-24 00:00:00
abstract::Sleep deprivation affects all aspects of health. Adverse health effects by sleep deviation are still underestimated and undervalued in clinical practice and, to a much greater extent in monitoring human health. We hypothesized that sleep deprivation-induced mild organ injuries; oxidative stress and inflammation might ...
journal_title:EXCLI journal
pub_type: 杂志文章
doi:10.17179/excli2015-245
更新日期:2015-05-18 00:00:00
abstract::Toxoplasma gondii is a common protozoan parasite, which infects warm-blooded mammals, including mice and humans, throughout the world. The negative effects of T. gondii infection on the human reproductive system have been documented, especially in females. However, only few studies have examined the effects of T. gond...
journal_title:EXCLI journal
pub_type: 杂志文章
doi:10.17179/excli2020-2052
更新日期:2020-08-24 00:00:00
abstract::Some debates exist regarding the association of diabetes mellitus (DM) with COVID-19 infection severity and mortality. In this study, we aimed to describe and compare the clinical characteristics and outcomes of hospitalized COVID-19 patients with and without DM. In this single-centered, retrospective, observational s...
journal_title:EXCLI journal
pub_type: 杂志文章
doi:10.17179/excli2020-2988
更新日期:2020-11-16 00:00:00
abstract::Genome editing technologies include techniques used for desired genetic modifications and allow the insertion, modification or deletion of specific DNA fragments. Recent advances in genome biology offer unprecedented promise for interdisciplinary collaboration and applications in gene editing. New genome editing techn...
journal_title:EXCLI journal
pub_type: 杂志文章,评审
doi:10.17179/excli2020-3070
更新日期:2021-01-04 00:00:00
abstract::An enzyme-coupled colorimetric assay for quantification of urinary sarcosine was developed. The proposed method is a specific reaction based on hydrogen peroxide (H2O2) formation via sarcosine oxidase (SOX). The liberated H2O2 reacts with Amplex Red in the presence of horseradish peroxidase (HRP) to produce the red-fl...
journal_title:EXCLI journal
pub_type: 杂志文章
doi:10.17179/excli2018-145
更新日期:2018-05-17 00:00:00
abstract::This study was undertaken to determine whether exposure of operating room personnel to inhalation anesthetics, including nitrous oxide, isoflurane, and sevoflurane was associated with any hepatotoxic or nephrotoxic changes. Fifty-two operating room personnel and 52 non-exposed subjects were studied. A questionnaire pe...
journal_title:EXCLI journal
pub_type: 杂志文章
doi:10.17179/excli2019-1911
更新日期:2020-03-25 00:00:00
abstract::The aim of this study was the design and evaluation of a novel plasma stable, pH-sensitive niosomal formulation of Mitoxantrone by a modified ethanol injection method. Cholesterol hemisuccinate was added instead of cholesterol in order to produce pH-sensitivity property and using PEG-Poly (monomethyl itaconate)-CholC6...
journal_title:EXCLI journal
pub_type: 杂志文章
doi:10.17179/excli2013-609
更新日期:2015-01-06 00:00:00
abstract::Previous studies proved the pro-angiogenic effect of Crocetin, a natural carotenoid dicarboxylic acid, in both in vivo and in vitro models. However, the exact mechanism of Crocetin action has not completely been elucidated yet. The current experiment was designed to find the activity of PI3K-Akt-eNOS axis after the tr...
journal_title:EXCLI journal
pub_type: 杂志文章
doi:10.17179/excli2019-1175
更新日期:2019-10-21 00:00:00
abstract::Morphological identification is a widespread procedure to assess the presence of apoptosis by visual inspection of the morphological characteristics or the fluorescence images. The procedure is lengthy and results are observer dependent. A quantitative automatic analysis is objective and would greatly help the routine...
journal_title:EXCLI journal
pub_type: 杂志文章
doi:
更新日期:2014-01-29 00:00:00
abstract::Pharmaceutical effluents contain toxic xenobiotics capable of contaminating aquatic environments. Untreated effluents are illegally discharged into aquatic environment in most developing countries. Pharmaceutical effluent induced alterations in biomarkers of genetic and systemic damage on rodents. However, information...
journal_title:EXCLI journal
pub_type: 杂志文章
doi:
更新日期:2019-02-06 00:00:00
abstract::Bladder cancer (BC) is the sixth most common malignancy in men and 17th in women. Exosomal long non-coding RNAs (lncRNAs) have been defined as a novel biomarker for BC. The aim of this study is to evaluate the clinical significance of urine exosomal PVT-1, ANRIL and PCAT-1 as a biomarker in BC patients with tumors cla...
journal_title:EXCLI journal
pub_type: 杂志文章
doi:10.17179/excli2019-1683
更新日期:2020-03-04 00:00:00
abstract::The chemical composition of the essential oils of different Allium nigrum L. organs and the antibacterial activity were evaluated. The study is particularly interesting because hitherto there are no reports on the antibacterial screening of this species with specific chemical composition. Therefore, essential oils fro...
journal_title:EXCLI journal
pub_type: 杂志文章
doi:
更新日期:2014-05-13 00:00:00
abstract::Dibutyltin dichloride (DBTC) is an organotin compound used as model for acute and chronic pancreatitis. Oxidative stress is one of the mechanisms of propagation of acinar cell injury in acute pancreatitis. Selenium is an essential cofactor in the antioxidant glutathione peroxidase pathway. Selenium levels are describe...
journal_title:EXCLI journal
pub_type: 杂志文章
doi:10.17179/excli2016-466
更新日期:2017-02-16 00:00:00
abstract::To date, a number of significant herbal drug interactions have their origins in the alteration of cytochrome P450 (CYP) activity by various phytochemicals. Among the most noteworthy are those involving St. John's wort and drugs metabolized by human CYP3A4 enzyme. This review article is the continued work from our prev...
journal_title:EXCLI journal
pub_type: 杂志文章,评审
doi:
更新日期:2014-08-20 00:00:00
abstract::The essential oil obtained from leaves of Melissa officinalis L. (Family of Lamiaceae) growing in Algeria, was investigated for its chemical composition and in vitro antimicrobial activity. The chemical composition was determined by hydrodistillation and analyzed by GC/MS and GC-FID. Sixty-three compounds were identif...
journal_title:EXCLI journal
pub_type: 杂志文章
doi:
更新日期:2014-07-17 00:00:00
abstract::Achillea eriophora (Asteraceae) is a medicinal plant commonly used in Iran. This study was performed to determine the cardiovascular effects of hydroethanolic extract of A. eriophora (HEAE) and the underlying mechanisms in anaesthetized rats. The acute effects of intravenous (i.v.) administration of different doses of...
journal_title:EXCLI journal
pub_type: 杂志文章
doi:10.17179/excli2016-529
更新日期:2016-12-07 00:00:00
abstract::Healthcare professionals, especially nurses and pre-hospital emergency (PHE) staff, are influenced by many stressors due to their responsibility to provide comfort as well as care and treatment of patients. The aim of the present study was to identify and rank the occupational stressors in nurses and PHE staff using F...
journal_title:EXCLI journal
pub_type: 杂志文章
doi:10.17179/excli2018-1505
更新日期:2018-08-20 00:00:00
abstract::One of the most fundamental operations in biological sequence analysis is multiple sequence alignment (MSA). The basic of multiple sequence alignment problems is to determine the most biologically plausible alignments of protein or DNA sequences. In this paper, an alignment method using genetic algorithm for multiple ...
journal_title:EXCLI journal
pub_type: 杂志文章
doi:10.17179/excli2015-302
更新日期:2015-12-15 00:00:00
abstract::Aromatase is a rate-limiting enzyme for estrogen biosynthesis that is overproduced in breast cancer tissue. To block the growth of breast tumors, aromatase inhibitors (AIs) are employed to bind and inhibit aromatase in order to lower the amount of estrogen produced in the body. Although a number of synthetic aromatase...
journal_title:EXCLI journal
pub_type: 杂志文章,评审
doi:10.17179/excli2018-1417
更新日期:2018-07-20 00:00:00
abstract::Ursolic acid (UA) is a pentacyclic triterpenoid carboxylic acid that is found in plants and herbal products. It is one of the chemopreventive agents, which can suppress cancer cell proliferation and induce apoptosis. UA possesses various biological activities including anticancer, anti-inflammatory, anti-oxidative and...
journal_title:EXCLI journal
pub_type: 杂志文章
doi:
更新日期:2013-02-08 00:00:00