Abstract:
:Hepatocellular carcinoma or Liver cancer (LC) is the sixth most common cancer and the fourth cause of death worldwide in 2018. There has not been a comprehensive study on the survival rate of patients with LC in Asia yet. Therefore, the present study was conducted to evaluate the survival rate of patients with LC in Asian countries. The methodology of the present study is based on the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analysis) statement. The researchers searched five international databases including Medline/PubMed, Scopus, Embase, Web of Knowledge and ProQuest until July 1, 2018. We also searched Google Scholar for detecting grey literature. The Newcastle-Ottawa Quality Assessment Form was used to evaluate the quality of selected papers. A total of 1425 titles were retrieved. 63 studies met the inclusion criteria. Based on the random-effect model one-year, three-year and five-year survival rate of LC were 34.8 % (95 % CI; 30.3-39.3), 19 % (95 % CI ; 18.2-21.8) and 18.1 % (95 % CI ;16.1-20.1) respectively. According to the results of our study, the LC survival rate in Asian countries is relatively lower than in Europe and North America.
journal_name
EXCLI Jjournal_title
EXCLI journalauthors
Hassanipour S,Vali M,Gaffari-Fam S,Nikbakht HA,Abdzadeh E,Joukar F,Pourshams A,Shafaghi A,Malakoutikhah M,Arab-Zozani M,Salehiniya H,Mansour-Ghanaei Fdoi
10.17179/excli2019-1842subject
Has Abstractpub_date
2020-01-13 00:00:00pages
108-130issn
1611-2156pii
Doc108journal_volume
19pub_type
杂志文章,评审相关文献
EXCLI Journal文献大全abstract::The liver is famous for its strong regenerative capacity, employing different modes of regeneration according to type and extent of injury. Mature liver cells are able to proliferate in order to replace the damaged tissue allowing the recovery of the parenchymal function. In more severe scenarios hepatocytes are belie...
journal_title:EXCLI journal
pub_type: 杂志文章,评审
doi:10.17179/excli2014-576
更新日期:2015-01-06 00:00:00
abstract::To our knowledge, in spite of several trials exploring the beneficial effect of n-3 polyunsaturated fatty acids (PUFA) on polycystic ovary syndrome (PCOS), no comprehensive evidence has investigated the effects of n-3 PUFA consumption on PCOS complications. Therefore, our aim was to conduct a review to investigate the...
journal_title:EXCLI journal
pub_type: 杂志文章,评审
doi:10.17179/excli2019-1534
更新日期:2019-07-25 00:00:00
abstract::Recently, bioinformatics has advanced to the level that it allows almost accurate prediction of molecular interactions that hold together a protein and a ligand in the bound state. For instance, the program AutoDock has been developed to provide a procedure for predicting the interaction of small molecules with macrom...
journal_title:EXCLI journal
pub_type: 杂志文章
doi:
更新日期:2013-09-23 00:00:00
abstract::Ursolic acid (UA) is a pentacyclic triterpenoid carboxylic acid that is found in plants and herbal products. It is one of the chemopreventive agents, which can suppress cancer cell proliferation and induce apoptosis. UA possesses various biological activities including anticancer, anti-inflammatory, anti-oxidative and...
journal_title:EXCLI journal
pub_type: 杂志文章
doi:
更新日期:2013-02-08 00:00:00
abstract::Oxidative stress is the common underlying mechanism of damage in ischemic stroke. Therefore, we aimed to evaluate the possible protective effects of polyhydroxylated fullerene derivatives on brain infarction and oxidative/nitrosative stress in a rat model of ischemic stroke. The experiment was performed by four groups...
journal_title:EXCLI journal
pub_type: 杂志文章
doi:10.17179/excli2016-309
更新日期:2016-06-20 00:00:00
abstract::Pharmaceutical effluents contain toxic xenobiotics capable of contaminating aquatic environments. Untreated effluents are illegally discharged into aquatic environment in most developing countries. Pharmaceutical effluent induced alterations in biomarkers of genetic and systemic damage on rodents. However, information...
journal_title:EXCLI journal
pub_type: 杂志文章
doi:
更新日期:2019-02-06 00:00:00
abstract::This study was undertaken to determine whether exposure of operating room personnel to inhalation anesthetics, including nitrous oxide, isoflurane, and sevoflurane was associated with any hepatotoxic or nephrotoxic changes. Fifty-two operating room personnel and 52 non-exposed subjects were studied. A questionnaire pe...
journal_title:EXCLI journal
pub_type: 杂志文章
doi:10.17179/excli2019-1911
更新日期:2020-03-25 00:00:00
abstract::Little is known about biogenically synthesized Zinc oxide nanoparticles (ZnONPs) from Isodon rugosus. Synthesis of metal oxide NPs from essential oil producing medicinal plants results in less harmful side effects to the human population as compared to chemically synthesized NPs. In this article, we report biogenic sy...
journal_title:EXCLI journal
pub_type: 杂志文章
doi:10.17179/excli2018-1327
更新日期:2018-07-16 00:00:00
abstract::Dibutyltin dichloride (DBTC) is an organotin compound used as model for acute and chronic pancreatitis. Oxidative stress is one of the mechanisms of propagation of acinar cell injury in acute pancreatitis. Selenium is an essential cofactor in the antioxidant glutathione peroxidase pathway. Selenium levels are describe...
journal_title:EXCLI journal
pub_type: 杂志文章
doi:10.17179/excli2016-466
更新日期:2017-02-16 00:00:00
abstract::Considering the therapeutic values of bioflavonoids in colon cancer treatment, six 2'-hydroxy chalcones (C1-C6) were synthesized, characterized and screened for in vitro cytotoxicity on human colon carcinoma (HCT116) and African green monkey kidney epithelial cells (Vero). Only C5 showed selective cytotoxicity against...
journal_title:EXCLI journal
pub_type: 杂志文章
doi:10.17179/excli2016-643
更新日期:2017-04-03 00:00:00
abstract::One of the most fundamental operations in biological sequence analysis is multiple sequence alignment (MSA). The basic of multiple sequence alignment problems is to determine the most biologically plausible alignments of protein or DNA sequences. In this paper, an alignment method using genetic algorithm for multiple ...
journal_title:EXCLI journal
pub_type: 杂志文章
doi:10.17179/excli2015-302
更新日期:2015-12-15 00:00:00
abstract::Everolimus (EVR), as a rapamycin analog, is a selective inhibitor of the mammalian target of rapamycin (mTOR) kinase and its associated signaling pathway. mTOR is a serine/threonine protein kinase and its hyperactivity is involved in the pathophysiology of Alzheimer's disease (AD) and associated cognitive deficits. Th...
journal_title:EXCLI journal
pub_type: 杂志文章
doi:10.17179/excli2018-1626
更新日期:2018-10-29 00:00:00
abstract::[This retracts the article DOI: 10.17179/excli2015-642.]. ...
journal_title:EXCLI journal
pub_type: 杂志文章,撤回出版物
doi:10.17179/excli2016-570
更新日期:2016-09-19 00:00:00
abstract::The present study deals with the isolation and partial purification of bioactive compounds from the crude methanol extracts of the leaves of Ageratum houstonianum (Asteraceae). The quantification and the identification of compounds in the crude extract and active bands isolated by preparative TLC were accomplished usi...
journal_title:EXCLI journal
pub_type: 杂志文章
doi:
更新日期:2012-02-28 00:00:00
abstract::This study aims to develop two alternate forms for Malay version of Auditory Verbal Learning Test (MAVLT) and to determine their equivalency and practice effect. Ninety healthy volunteers were subjected to the following neuropsychological tests at baseline, and at one month interval according to their assigned group; ...
journal_title:EXCLI journal
pub_type: 杂志文章
doi:10.17179/excli2015-280
更新日期:2015-07-07 00:00:00
abstract::Renin Angiotensin Aldosterone System (RAAS) plays an important role in the development of hypertension. On the other hand, hypertension is a well-known and independent risk factor for cognitive impairment. The aim of the present study was to evaluate the relationship of blood pressure control, plasma angiotensin pepti...
journal_title:EXCLI journal
pub_type: 杂志文章
doi:10.17179/excli2016-725
更新日期:2017-03-10 00:00:00
abstract::Patients with diabetes tend to have an increased risk of osteoporosis that may be related to hyperglycemia. In vitro evidence has shown that high glucose can affect the proliferation and osteogenic differentiation of mesenchymal stem cells (MSCs). Tissue regeneration depends mainly on MSCs. However, the exact mechanis...
journal_title:EXCLI journal
pub_type: 杂志文章
doi:
更新日期:2013-06-27 00:00:00
abstract::Achillea eriophora (Asteraceae) is a medicinal plant commonly used in Iran. This study was performed to determine the cardiovascular effects of hydroethanolic extract of A. eriophora (HEAE) and the underlying mechanisms in anaesthetized rats. The acute effects of intravenous (i.v.) administration of different doses of...
journal_title:EXCLI journal
pub_type: 杂志文章
doi:10.17179/excli2016-529
更新日期:2016-12-07 00:00:00
abstract::Nephropathy associated with type 2 diabetes is the single most common cause of end-stage renal disease. The aim of the present study was to evaluate the preventive effect of ethanolic extract of Embelia ribes fruit (EER) against high fat diet (HFD) and low dose streptozotocin (STZ)-induced diabetic nephrotoxicity in W...
journal_title:EXCLI journal
pub_type: 杂志文章
doi:
更新日期:2013-09-24 00:00:00
abstract::Objective: Although osteoarthritis (OA) is widely accepted as a degenerative disease, autoimmune processes are believed to be involved in the pathogenesis. There are limited studies in this area and most of them focused on antibodies against chondrocyte membrane. In an attempt to address the paucity of evidence in thi...
journal_title:EXCLI journal
pub_type: 杂志文章
doi:
更新日期:2012-09-07 00:00:00
abstract::Curcuminoids are dietary complexes extracted from the seeds of Curcuma longa L. that contain curcumin, bisdemethoxycurcumin and desmethoxycurcumin. Curcuminoids are popular for their pleiotropic therapeutic functions, such as their anti-inflammatory and anti-oxidant effects. Nonetheless, their clinical use is associat...
journal_title:EXCLI journal
pub_type: 杂志文章
doi:10.17179/excli2019-1366
更新日期:2019-06-17 00:00:00
abstract::As a dynamic system in which different factors affect human performance via dynamic interactions, mental workload needs a dynamic measure to monitor its factors and evidence in a complicated system, an approach that is lacking in the literature. The present study introduces a system dynamics-based model for designing ...
journal_title:EXCLI journal
pub_type: 杂志文章
doi:10.17179/excli2019-1372
更新日期:2019-07-11 00:00:00
abstract::The aim of this study was to evaluate the effect of acute and chronic physical and psychological stressors on the induction of oxidative stress in male rat liver. Male Wistar rats were randomly divided into 3 groups as following: control, physical and psychological stress groups. Stress was induced by communication bo...
journal_title:EXCLI journal
pub_type: 杂志文章
doi:
更新日期:2014-02-24 00:00:00
abstract::Hepatitis C is a major global health burden and Egypt has the highest prevalence of hepatitis C virus (HCV) worldwide. The current study was designed to evaluate the beneficial therapeutic effects of ethanolic extracts of Nigella sativa, Zingiber officinale and their mixture in Egyptian HCV patients. Sixty volunteer p...
journal_title:EXCLI journal
pub_type: 杂志文章
doi:
更新日期:2013-11-11 00:00:00
abstract::A reliable biomarker has not been identified to predict the outcome of traumatic brain injury (TBI) in children. Therefore, the present systematic review and meta-analysis aimed to assess the association between neuron specific enolase (NSE) and traumatic brain injury (TBI) in children. Two independent reviewers searc...
journal_title:EXCLI journal
pub_type: 杂志文章
doi:10.17179/excli2017-405
更新日期:2017-07-03 00:00:00
abstract::To date, a number of significant herbal drug interactions have their origins in the alteration of cytochrome P450 (CYP) activity by various phytochemicals. Among the most noteworthy are those involving St. John's wort and drugs metabolized by human CYP3A4 enzyme. This review article is the continued work from our prev...
journal_title:EXCLI journal
pub_type: 杂志文章,评审
doi:
更新日期:2014-08-20 00:00:00
abstract::The chemical composition of the essential oils of different Allium nigrum L. organs and the antibacterial activity were evaluated. The study is particularly interesting because hitherto there are no reports on the antibacterial screening of this species with specific chemical composition. Therefore, essential oils fro...
journal_title:EXCLI journal
pub_type: 杂志文章
doi:
更新日期:2014-05-13 00:00:00
abstract::The aim was to establish a cell culture of adult primary bovine hepatocytes obtained from liver following slaughter and to cultivate the cells in a sandwich culture. Cells and medium samples were taken after separation of cells (day 0), during monolayer (days 1, 2 and 3) and during sandwich culture (days 1, 2, 3, 4, 7...
journal_title:EXCLI journal
pub_type: 杂志文章
doi:10.17179/excli2016-794
更新日期:2016-12-22 00:00:00
abstract::Morphological identification is a widespread procedure to assess the presence of apoptosis by visual inspection of the morphological characteristics or the fluorescence images. The procedure is lengthy and results are observer dependent. A quantitative automatic analysis is objective and would greatly help the routine...
journal_title:EXCLI journal
pub_type: 杂志文章
doi:
更新日期:2014-01-29 00:00:00
abstract::Some debates exist regarding the association of diabetes mellitus (DM) with COVID-19 infection severity and mortality. In this study, we aimed to describe and compare the clinical characteristics and outcomes of hospitalized COVID-19 patients with and without DM. In this single-centered, retrospective, observational s...
journal_title:EXCLI journal
pub_type: 杂志文章
doi:10.17179/excli2020-2988
更新日期:2020-11-16 00:00:00