当前位置： SCI文献检索 > Biomed Research International期刊下所有文献 > Invasive Hemodynamic Assessment of Cardiac Output State after MitraClip Therapy in Nonanaesthetized Patients with Functional Mitral Regurgitation.

Invasive Hemodynamic Assessment of Cardiac Output State after MitraClip Therapy in Nonanaesthetized Patients with Functional Mitral Regurgitation.

Abstract：

:Background. Surgical correction of mitral regurgitation (MR) can lead to postoperative low cardiac output state. We aimed to assess the acute hemodynamic changes after percutaneous MitraClip therapy (a unique model without influence of factors linked to surgical procedure) in patients with functional MR without the influence of general anaesthesia. Methods. We studied invasive hemodynamic parameters in 23 patients before procedure (conscious, nonsedated patients), during procedure (intubated patients), and the first day after MitraClip implantation (conscious, extubated patients). Results. Mitral valve clipping significantly increased cardiac index (CI) (from 2.0 ± 0.5 to 3.3 ± 0.6 L/min/m2; p < 0.01). Conversely, there was significant reduction in the mean pulmonary capillary wedge pressure (PCWP) (from 18.6 ± 5.7 to 10.5 ± 3.8 mmHg; p < 0.01), mean pulmonary artery pressure (from 29.8 ± 10.9 to 25.2 ± 10.3 mmHg; p = 0.03), and pulmonary vascular resistance index (from 531 ± 359 to 365 ± 193 dyn·s·cm-5/m2; p = 0.03). Conclusions. The functional MR therapy with percutaneous MitraClip device results in significant increase in CI (+66%) and concomitant decrease in PCWP (-42%). None of our patients developed low cardiac output state. Our results support the idea that significant part of low cardiac output state after cardiac surgery is due to surgery related factors rather than due to increase in afterload after MR elimination.

journal_name

Biomed Res Int

journal_title

BioMed research international

authors

Bednar F,Budesinsky T,Linkova H,Kocka V

doi

10.1155/2016/6296972

subject

Has Abstract

pub_date

2016-01-01 00:00:00

pages

6296972

eissn

2314-6133

issn

2314-6141

journal_volume

2016

pub_type

临床试验,杂志文章

相关文献

Biomed Research International文献大全
  • Prediction of the Impact of Deleterious Nonsynonymous Single Nucleotide Polymorphisms on the Human RRM2B Gene: A Molecular Modeling Study.

    abstract：:RRM2B gene encodes ribonucleoside-diphosphate reductase subunit M2 B, the p53-inducible small subunit (p53R2) of ribonucleotide reductase (RNR), an enzyme catalyzing dNTP synthesis for mitochondrial DNA. Defects in this gene may cause severe mitochondrial disease affecting mainly the nervous system. This study is aime...

    journal_title：BioMed research international

    pub_type： 杂志文章

    doi：10.1155/2020/7614634

    authors： Ait El Cadi C,Krami AM,Charoute H,Elkarhat Z,Sifeddine N,Lakhiari H,Rouba H,Barakat A,Nahili H

    更新日期：2020-07-25 00:00:00

  • Emergency versus Elective Cervical Cerclage: An Audit of Our First Two Years of Service.

    abstract：:One of the biggest obstetric challenges is the diagnosis and management of a short cervix as cervical length has an inverse relationship with risk of preterm birth. A cervical cerclage is a surgical procedure to reduce the risk of preterm birth and can be placed in an elective or emergency setting. This is a retrospec...

    journal_title：BioMed research international

    pub_type： 临床试验,杂志文章,多中心研究

    doi：10.1155/2018/2065232

    authors： Vasudeva N,Reddington C,Bogdanska M,De Luca L

    更新日期：2018-09-30 00:00:00

  • Application of stochastic automata networks for creation of continuous time Markov chain models of voltage gating of gap junction channels.

    abstract：:The primary goal of this work was to study advantages of numerical methods used for the creation of continuous time Markov chain models (CTMC) of voltage gating of gap junction (GJ) channels composed of connexin protein. This task was accomplished by describing gating of GJs using the formalism of the stochastic autom...

    journal_title：BioMed research international

    pub_type： 杂志文章

    doi：10.1155/2015/936295

    authors： Snipas M,Pranevicius H,Pranevicius M,Pranevicius O,Paulauskas N,Bukauskas FF

    更新日期：2015-01-01 00:00:00

  • A Kinase Anchoring Protein 9 Is a Novel Myosin VI Binding Partner That Links Myosin VI with the PKA Pathway in Myogenic Cells.

    abstract：:Myosin VI (MVI) is a unique motor protein moving towards the minus end of actin filaments unlike other known myosins. Its important role has recently been postulated for striated muscle and myogenic cells. Since MVI functions through interactions of C-terminal globular tail (GT) domain with tissue specific partners, w...

    journal_title：BioMed research international

    pub_type： 杂志文章

    doi：10.1155/2015/816019

    authors： Karolczak J,Sobczak M,Skowronek K,Rędowicz MJ

    更新日期：2015-01-01 00:00:00

  • The In Vitro Lipolysis of Lipid-Based Drug Delivery Systems: A Newly Identified Relationship between Drug Release and Liquid Crystalline Phase.

    abstract：:The purpose of this study was to offer a new insight into the microstructure changes during in vitro lipolysis of five lipid-based drug delivery formulations belonging to different lipid formulation types. Five lipid-based formulations of indomethacin were investigated using an in vitro lipolysis model. During lipolys...

    journal_title：BioMed research international

    pub_type： 杂志文章

    doi：10.1155/2016/2364317

    authors： Xiao L,Yi T,Liu Y,Zhou H

    更新日期：2016-01-01 00:00:00

  • Balance dysfunction in Parkinson's disease.

    abstract：:Stability and mobility in functional motor activities depend on a precise regulation of phasic and tonic muscular activity that is carried out automatically, without conscious awareness. The sensorimotor control of posture involves a complex integration of multisensory inputs that results in a final motor adjustment p...

    journal_title：BioMed research international

    pub_type： 杂志文章,评审

    doi：10.1155/2015/434683

    authors： Rinalduzzi S,Trompetto C,Marinelli L,Alibardi A,Missori P,Fattapposta F,Pierelli F,Currà A

    更新日期：2015-01-01 00:00:00

  • Serum Human Epididymis Protein 4 is Associated with Renal Function and Diabetic Kidney Disease in Patients with Type 2 Diabetes Mellitus.

    abstract：:Human epididymis protein 4 (HE4) is an available tumor biomarker mainly for detecting ovarian cancer. However, it is unknown whether it can be a novel indicator for diagnosis of diabetic kidney disease (DKD). The aim of this study was to investigate the possibility of serum HE4 as a novel biomarker for DKD in patients...

    journal_title：BioMed research international

    pub_type： 杂志文章

    doi：10.1155/2019/4831459

    authors： Zhang M,Zhao B,Xie J,Liang Y,Yang Z

    更新日期：2019-11-11 00:00:00

  • Intra-QT spectral coherence as a possible noninvasive marker of sustained ventricular tachycardia.

    abstract：:Sudden cardiac death is the main cause of mortality in patients affected by chronic heart failure (CHF) and with history of myocardial infarction. No study yet investigated the intra-QT phase spectral coherence as a possible tool in stratifying the arrhythmic susceptibility in patients at risk of sudden cardiac death ...

    journal_title：BioMed research international

    pub_type： 杂志文章

    doi：10.1155/2014/583035

    authors： Piccirillo G,Moscucci F,Persi A,Di Barba D,Pappadà MA,Rossi P,Quaglione R,Nguyen BL,Barillà F,Casenghi M,Magrì D

    更新日期：2014-01-01 00:00:00

  • Functional development of the circadian clock in the zebrafish pineal gland.

    abstract：:The zebrafish constitutes a powerful model organism with unique advantages for investigating the vertebrate circadian timing system and its regulation by light. In particular, the remarkably early and rapid development of the zebrafish circadian system has facilitated exploring the factors that control the onset of ci...

    journal_title：BioMed research international

    pub_type： 杂志文章,评审

    doi：10.1155/2014/235781

    authors： Ben-Moshe Z,Foulkes NS,Gothilf Y

    更新日期：2014-01-01 00:00:00

  • Differential Diagnosis of Parotid Gland Tumors: Role of Shear Wave Elastography.

    abstract：AIM:To create a predictive score for the discrimination between benign and malignant parotid tumors using elastographic parameters and to compare its sensitivity and specificity with standard ultrasound. METHODS:A total of 124 patients with parotid gland lesions for whom surgery was planned were examined using convent...

    journal_title：BioMed research international

    pub_type： 杂志文章

    doi：10.1155/2017/9234672

    authors： Heřman J,Sedláčková Z,Vachutka J,Fürst T,Salzman R,Vomáčka J,Heřman M

    更新日期：2017-01-01 00:00:00

  • The Association between Cerebral White Matter Lesions and Plasma Omega-3 to Omega-6 Polyunsaturated Fatty Acids Ratio to Cognitive Impairment Development.

    abstract：OBJECTIVE:Cerebral white matter hyperintensity (WMH) with magnetic resonance imaging (MRI) has a potential for predicting cognitive impairment. Serum polyunsaturated fatty acid (PUFA) levels are important for evaluating the extent of atherosclerosis. We investigated whether abnormal PUFA levels affected WMH grading and...

    journal_title：BioMed research international

    pub_type： 杂志文章

    doi：10.1155/2015/153437

    authors： Suwa M,Yamaguchi S,Komori T,Kajimoto S,Kino M

    更新日期：2015-01-01 00:00:00

  • Cyclic Stretch Enhances Osteogenic Differentiation of Human Periodontal Ligament Cells via YAP Activation.

    abstract：:Periodontal remodeling and alveolar bone resorption and formation play essential roles during orthodontic tooth movement (OTM). In the process, human periodontal ligament cells (HPDLCs) sense and respond to orthodontic forces, contributing to the alveolar bone formation. However, the underlying mechanism in this proce...

    journal_title：BioMed research international

    pub_type： 杂志文章

    doi：10.1155/2018/2174824

    authors： Yang Y,Wang BK,Chang ML,Wan ZQ,Han GL

    更新日期：2018-11-05 00:00:00

  • Challenges of Longevity: Safety of Vaginal and Laparoscopic Urogynecological Procedures in Septuagenarians and Older Patients.

    abstract：:Introduction. Pelvic organ prolapse (POP) and urinary incontinence (UI) have increasing prevalence in the elderly population. The aim of this study was to compare the comorbidities of these procedures between <70 y/o and ≥70 y/o patients. Materials and Methods. In our retrospective study over a period of 2.5 years, 40...

    journal_title：BioMed research international

    pub_type： 杂志文章

    doi：10.1155/2016/5184595

    authors： Joukhadar R,Wöckel A,Herr D,Paulus V,Radosa J,Hamza A,Solomayer E,Baum S

    更新日期：2016-01-01 00:00:00

  • Norvaline Reduces Blood Pressure and Induces Diuresis in Rats with Inherited Stress-Induced Arterial Hypertension.

    abstract：:Growing evidence suggests that increased arginase activity affects vital bioprocesses in various systems and universally mediates the pathogenesis of numerous metabolic diseases. The adverse effects of arginase are associated with a severe decline in L-arginine bioavailability, which leads to nitric oxide synthase sub...

    journal_title：BioMed research international

    pub_type： 杂志文章

    doi：10.1155/2020/4935386

    authors： Gilinsky MA,Polityko YK,Markel AL,Latysheva TV,Samson AO,Polis B,Naumenko SE

    更新日期：2020-02-12 00:00:00

  • Isorhamnetin Induces Melanoma Cell Apoptosis via the PI3K/Akt and NF-κB Pathways.

    abstract：:Malignant melanoma is characterized by its bad prognosis for aggressiveness, drug resistance, and early metastasis. Isorhamnetin (3'-methoxy-3,4',5,7-tetrahydroxyflavone; IH) is a natural flavonoid that has been investigated for its antitumor effects in breast cancer, colon cancer, and gastric cancer through inducing ...

    journal_title：BioMed research international

    pub_type： 杂志文章

    doi：10.1155/2020/1057943

    authors： Duan R,Liang X,Chai B,Zhou Y,Du H,Suo Y,Chen Z,Li Q,Huang X

    更新日期：2020-05-05 00:00:00

  • Effects of Polyphenol Compounds and Nitrogen Oxide Donors on Lipid Oxidation, Membrane-Skeletal Proteins, and Erythrocyte Structure under Hypoxia.

    abstract：:This study shows that membrane-associated cytoskeletal protein structures and the erythrocyte morphology undergo profound changes during hypoxia. Hypoxia also intensified oxidative processes in the lipid phase of the bilayer of red blood cell membranes. Sodium nitroprusside impaired the morphology of red blood cells a...

    journal_title：BioMed research international

    pub_type： 杂志文章

    doi：10.1155/2019/6758017

    authors： Revin VV,Gromova NV,Revina ES,Prosnikova KV,Revina NV,Bochkareva SS,Stepushkina OG,Grunyushkin IP,Tairova MR,Incina VI

    更新日期：2019-12-07 00:00:00

  • Association between the MMP-1-1607 1G/2G Polymorphism and Osteoarthritis Risk: A Systematic Review and Meta-Analysis.

    abstract：Background:Osteoarthritis (OA) is a common disease characterized by articular cartilage degeneration and secondary hyperosteogenesis. Genetic factors are associated with the occurrence of OA. While several studies have shown that the matrix metalloproteinase-1- (MMP-1-) 1607 1G/2G (rs1799750) polymorphism may be relate...

    journal_title：BioMed research international

    pub_type： 杂志文章,评审

    doi：10.1155/2020/5190587

    authors： Liu J,Wang G,Peng Z

    更新日期：2020-05-20 00:00:00

  • Micro-Raman Vibrational Identification of 10-MDP Bond to Zirconia and Shear Bond Strength Analysis.

    abstract：:So far, there is no report regarding the micro-Raman vibrational fingerprint of the bonds between 10-methacryloyloxy-decyl dihydrogen phosphate (10-MDP) and zirconia ceramics. Thus, the aim of this study was to identify the Raman vibrational peaks related to the bonds of 10-MDP with zirconia, as well as the influence ...

    journal_title：BioMed research international

    pub_type： 杂志文章

    doi：10.1155/2017/8756396

    authors： De-Paula DM,Loguercio AD,Reis A,Frota NM,Melo R,Yoshihara K,Feitosa VP

    更新日期：2017-01-01 00:00:00

  • The Effect of Longer versus Shorter Duration of Supervised Physiotherapy after ACL Reconstruction on the Vertical Jump Landing Limb Symmetry.

    abstract：:The study investigated the vertical jump landing limb symmetry after ACLR between a group of patients receiving a longer supervised physiotherapeutic procedure and following a shorter supervised physiotherapy. Group I (n = 20) and Group II (n = 15) were males averagely 30 weeks after ACLR. The time since ACLR in both ...

    journal_title：BioMed research international

    pub_type： 杂志文章

    doi：10.1155/2018/7519467

    authors： Królikowska A,Czamara A,Szuba Ł,Reichert P

    更新日期：2018-04-23 00:00:00

  • Mitochondria Associated MicroRNA Expression Profiling of Heart Failure.

    abstract：:Heart failure (HF) is associated with mitochondrial dysfunction and energy metabolism impairment. MicroRNAs are implicated in the development of heart failure. However, the mitochondria enriched microRNA during heart failure remains elusive. Here, we generated a pressure overload-induced early and late stage heart fai...

    journal_title：BioMed research international

    pub_type： 杂志文章

    doi：10.1155/2017/4042509

    authors： Wang X,Song C,Zhou X,Han X,Li J,Wang Z,Shang H,Liu Y,Cao H

    更新日期：2017-01-01 00:00:00

  • Distinct action of flavonoids, myricetin and quercetin, on epithelial Cl⁻ secretion: useful tools as regulators of Cl⁻ secretion.

    abstract：:Epithelial Cl(-) secretion plays important roles in water secretion preventing bacterial/viral infection and regulation of body fluid. We previously suggested that quercetin would be a useful compound for maintaining epithelial Cl(-) secretion at a moderate level irrespective of cAMP-induced stimulation. However, we n...

    journal_title：BioMed research international

    pub_type： 杂志文章

    doi：10.1155/2014/902735

    authors： Sun H,Niisato N,Nishio K,Hamilton KL,Marunaka Y

    更新日期：2014-01-01 00:00:00

  • The Italian National External quality assessment program in molecular genetic testing: results of the VII round (2010-2011).

    abstract：:Since 2001 the Istituto Superiore di Sanità established a quality assurance programme for molecular genetic testing that covers four pathologies: Cystic Fibrosis (CF), Beta Thalassemia (BT), Fragile X Syndrome (FX), and Familial Adenomatous Polyposis Coli (APC). Since 2009 this activity is an institutional activity an...

    journal_title：BioMed research international

    pub_type： 杂志文章

    doi：10.1155/2013/739010

    authors： Censi F,Tosto F,Floridia G,Marra M,Salvatore M,Baffico AM,Grasso M,Melis MA,Pelo E,Radice P,Ravani A,Rosatelli C,Resta N,Russo S,Seia M,Varesco L,Falbo V,Taruscio D

    更新日期：2013-01-01 00:00:00

  • Relationship between malnutrition and the number of permanent teeth in Filipino 10- to 13-year-olds.

    abstract：:In the present study, we determined whether there is a delay in the eruption of permanent teeth (PT) among Filipino adolescents with stunting or thinness. Height, weight, and number of PT were recorded in 1554 Filipino 10- to 13-year-olds (711 boys; 843 girls). z-scores for height (HAZ) and body mass index (BMI) were ...

    journal_title：BioMed research international

    pub_type： 杂志文章

    doi：10.1155/2013/205950

    authors： Heinrich-Weltzien R,Zorn C,Monse B,Kromeyer-Hauschild K

    更新日期：2013-01-01 00:00:00

  • Autophagy, Warburg, and Warburg reverse effects in human cancer.

    abstract：:Autophagy is a highly regulated-cell pathway for degrading long-lived proteins as well as for clearing cytoplasmic organelles. Autophagy is a key contributor to cellular homeostasis and metabolism. Warburg hypothesized that cancer growth is frequently associated with a deviation of a set of energy generation mechanism...

    journal_title：BioMed research international

    pub_type： 杂志文章,评审

    doi：10.1155/2014/926729

    authors： Gonzalez CD,Alvarez S,Ropolo A,Rosenzvit C,Bagnes MF,Vaccaro MI

    更新日期：2014-01-01 00:00:00

  • MoDeSuS: A Machine Learning Tool for Selection of Molecular Descriptors in QSAR Studies Applied to Molecular Informatics.

    abstract：:The selection of the most relevant molecular descriptors to describe a target variable in the context of QSAR (Quantitative Structure-Activity Relationship) modelling is a challenging combinatorial optimization problem. In this paper, a novel software tool for addressing this task in the context of regression and clas...

    journal_title：BioMed research international

    pub_type： 杂志文章

    doi：10.1155/2019/2905203

    authors： Martínez MJ,Razuc M,Ponzoni I

    更新日期：2019-02-17 00:00:00

  • Intracranial Infections in Neurological Surgery: The Changes of Circular RNA Expression and Their Possible Function Mechanism.

    abstract：Methods:circRNA expression was analysed in six cerebrospinal fluid (CSF) samples from three patients of the infectious and noninfectious phases using an Arraystar Human circRNA Array. Differentially altered circRNAs were validated by quantitative real-time polymerase chain reaction (qRT-PCR) in the 66 CSF samples of 33...

    journal_title：BioMed research international

    pub_type： 杂志文章

    doi：10.1155/2020/2536272

    authors： Niu J,Xu H,Yang B

    更新日期：2020-05-02 00:00:00

  • Improvement in the Detection of Cystic Metastatic Papillary Thyroid Carcinoma by Measurement of Thyroglobulin in Aspirated Fluid.

    abstract：:Cystic change in metastatic lymph nodes of papillary thyroid carcinoma (PTC) is a diagnostic challenge for fine needle aspiration (FNA) because of the scant cellularity. The aim of this study was to evaluate the measurement of thyroglobulin in fine needle aspirate (Tg-FNA) for detecting metastatic PTC in patients with...

    journal_title：BioMed research international

    pub_type： 杂志文章

    doi：10.1155/2016/8905916

    authors： Wang Y,Zhao H,Wang YX,Wang MJ,Zhang ZH,Zhang L,Zhang B,Ahuja AT,Zhou CW,Jiang YX,Guo HQ

    更新日期：2016-01-01 00:00:00

  • Retracted: Long Noncoding RNA KIAA0125 Potentiates Cell Migration and Invasion in Gallbladder Cancer.

    abstract：:[This retracts the article DOI: 10.1155/2015/108458.]. ...

    journal_title：BioMed research international

    pub_type： 杂志文章,撤回出版物

    doi：10.1155/2017/3471417

    authors： International BR

    更新日期：2017-01-01 00:00:00

  • Validation of Reference Genes for Gene Expression Normalization in RAW264.7 Cells under Different Conditions.

    abstract：:RAW264.7 is a macrophage strain derived from mice tumour and shows a significant ability in antigen uptake. Real-time quantitative PCR (RT-qPCR) is one of the most commonly used methods in gene studies and requires suitable reference genes to normalize and quantitate the expression of gene of interest with sensitivity...

    journal_title：BioMed research international

    pub_type： 杂志文章

    doi：10.1155/2019/6131879

    authors： Bao Z,Huang Y,Chen J,Wang Z,Qian J,Xu J,Zhao Y

    更新日期：2019-05-16 00:00:00

  • DNA Primase Subunit 1 Expression in Hepatocellular Carcinoma and Its Clinical Implication.

    abstract：:DNA Primase Subunit 1 (PRIM1) is crucial for cancer development and progression. However, there remains a lack of comprehension concerning the clinical implication of PRIM1 in HCC. Here, aberrant expression of PRIM1 was identified in HCC according to available databases. The prognostic value of PRIM1 in patients prese...

    journal_title：BioMed research international

    pub_type： 杂志文章

    doi：10.1155/2020/9689312

    authors： Zhang Y,Li L,Liu R,Zeng C

    更新日期：2020-08-22 00:00:00