The In Vitro Lipolysis of Lipid-Based Drug Delivery Systems: A Newly Identified Relationship between Drug Release and Liquid Crystalline Phase.

abstract：Background and Aims:Contrast-induced nephropathy (CIN) is a relatively infrequent complication after percutaneous coronary intervention (PCI) in patients with ST-elevation myocardial infarction (STEMI). However, little is known about the association between cytochrome c (cyt c) and increased risk of CIN. We conducted t...

journal_title：BioMed research international

authors： Tang C,Hou J,Yan G,Qiao Y,Wang D,Zhu B,Liu B,Luo E,Nawabi AQ,Chen L

更新日期：2019-01-23 00:00:00

abstract：:Toll-like receptors (TLRs), a critical family of pattern recognition receptors (PRRs), are responsible for the innate immune responses via signalling pathways to provide effective host defence against pathogen infections. However, TLR-signalling pathways are also likely to stringently regulate tissue maintenance and h...

journal_title：BioMed research international

authors： He X,Jing Z,Cheng G

更新日期：2014-01-01 00:00:00

abstract：:Aim. This study aimed to evaluate the reliability of 3D-TMT, previously used only for dynamic testing, in a static cephalometric evaluation. Material and Method. A group of 40 patients (20 males and 20 females; mean age 14.2 ± 1.2 years; 12-18 years old) was included in the study. The measurements obtained by the 3D-T...

journal_title：BioMed research international

authors： Mummolo S,Nota A,Marchetti E,Padricelli G,Marzo G

更新日期：2016-01-01 00:00:00

abstract：:The plant cytoskeleton, including microtubules and microfilaments, is one of the important factors in determining the polarity of cell division and growth, as well as the interaction of plants with invading pathogens. In defense responses of wheat against the stripe rust (Puccinia striiformis f. sp. tritici) infection...

journal_title：BioMed research international

authors： Wang J,Wang Y,Liu X,Xu Y,Ma Q

更新日期：2016-01-01 00:00:00

abstract：:Both human adipose tissue-derived mesenchymal stem cells (ASCs) and umbilical cord-derived mesenchymal stem cells (UC-MSCs) have been explored as attractive mesenchymal stem cells (MSCs) sources, but very few parallel comparative studies of these two cell types have been made. We designed a side-by-side comparative st...

journal_title：BioMed research international

authors： Hu L,Hu J,Zhao J,Liu J,Ouyang W,Yang C,Gong N,Du L,Khanal A,Chen L

更新日期：2013-01-01 00:00:00

abstract：:Despite many advances in the diagnosis and treatment of colorectal cancer (CRC), its incidence and mortality rates continue to make an impact worldwide and in some countries rates are mounting. Over the past decade, liquid biopsies have been the object of fundamental and clinical research with regard to the different ...

journal_title：BioMed research international

authors： Christou N,Meyer J,Popeskou S,David V,Toso C,Buchs N,Liot E,Robert J,Ris F,Mathonnet M

更新日期：2019-12-04 00:00:00

abstract：:The potential of three submerged aquatic plant species (Cabomba piauhyensis, Egeria densa, and Hydrilla verticillata) to be used for As, Al, and Zn phytoremediation was tested. The plants were exposed for 14 days under hydroponic conditions to mine waste water effluents in order to assess the suitability of the aquati...

journal_title：BioMed research international

authors： Abu Bakar AF,Yusoff I,Fatt NT,Othman F,Ashraf MA

更新日期：2013-01-01 00:00:00

abstract：:Myricetin has been reported as a promising chemopreventive compound with multiple biofunctions. To evaluate its influence on gene expressions in genome-wide set and further investigate its anti-inflammatory property, the present study performed Gene Ontology and Ingenuity Pathway Analysis (IPA) to describe the basic g...

journal_title：BioMed research international

authors： Li T,Zhu J,Deng F,Wu W,Zheng Z,Lv C,Li Y,Xiang W,Lu X,Qin S

更新日期：2019-03-07 00:00:00

abstract：:In vitro studies reveal that androgens, oestrogens, and their metabolites play a crucial role in prostate homeostasis. Most of the studies evaluated intraprostatic hormone metabolism using cell lines or preprocessed specimens. Using an ex vivo model of intact tissue cultures with preserved architecture, we characteriz...

journal_title：BioMed research international

authors： Gianfrilli D,Pierotti S,Pofi R,Leonardo C,Ciccariello M,Barbagallo F

更新日期：2014-01-01 00:00:00

abstract：:New and innovative treatment strategies for cancer patients in the fields of immunotherapy and radiotherapy are rapidly developing in parallel. Among the most promising preclinical treatment approaches is combining immunotherapy with radiotherapy where early data suggest synergistic effects in several tumor model syst...

journal_title：BioMed research international

authors： Zeng J,Harris TJ,Lim M,Drake CG,Tran PT

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:An increased prevalence of metabolic syndrome including nonalcoholic fatty liver disease (NAFLD) was reported in psoriasis. NAFLD can progress to nonalcoholic steatohepatitis and fibrosis. Transient elastography (TE) is a noninvasive liver fibrosis assessment. We evaluated the prevalence of significant liver...

journal_title：BioMed research international

authors： Pongpit J,Porntharukchareon S,Kaewduang P,Promson K,Stitchantrakul W,Petraksa S,Thakkinstian A,Kositchaiwat C,Rajatanavin N,Sobhonslidsuk A

更新日期：2016-01-01 00:00:00

abstract：:Coconut palm (Cocos nucifera) is an important commercial crop in many tropical countries, but its industry generates large amounts of residue. One way to address this problem is to use this residue, coconut husk, to produce second-generation (2G) ethanol. The aim of this review is to describe the methods that have bee...

journal_title：BioMed research international

authors： Bolivar-Telleria M,Turbay C,Favarato L,Carneiro T,de Biasi RS,Fernandes AAR,Santos AMC,Fernandes PMB

更新日期：2018-09-27 00:00:00

abstract：:Different batches of atorvastatin, represented by two immediate release formulation designs, were studied using a novel dynamic dissolution apparatus, simulating stomach and small intestine. A universal dissolution method was employed which simulated the physiology of human gastrointestinal tract, including the precis...

journal_title：BioMed research international

authors： Čulen M,Tuszyński PK,Polak S,Jachowicz R,Mendyk A,Dohnal J

更新日期：2015-01-01 00:00:00

abstract：:Deep venous thrombosis (DVT) constitutes a great threat to health worldwide. Endothelial cell injury and dysfunction comprise the critical contributor for the development of DVT. However, the mechanism behind it remains poorly elucidated. The study is aimed at investigating the role of microRNA-122 (miR-122) and oxida...

journal_title：BioMed research international

authors： Li HQ,Pan ZY,Yang Z,Zhang DB,Chen Q

更新日期：2020-10-27 00:00:00

abstract：:Objectives. To investigate the protective effects of tropisetron on acetaminophen- (APAP-) induced liver injury in a mice model. Methods. C57BL/6 male mice were given tropisetron (0.3 to 10 mg/kg) 30 minutes before a hepatotoxic dose of acetaminophen (300 mg/kg) intraperitoneally. Twenty hours after APAP intoxication,...

journal_title：BioMed research international

authors： Liu FC,Lee HC,Liao CC,Li AH,Yu HP

更新日期：2016-01-01 00:00:00

abstract：:The effects of obstruction on renal function are the consequence of many factors that profoundly alter all components of glomerular function. Besides the acute effects on glomerular filtration rate and tubule function, a chronic obstruction induces tubular and interstitial injury that results from the activation of di...

journal_title：BioMed research international

authors： Lucarelli G,Mancini V,Galleggiante V,Rutigliano M,Vavallo A,Battaglia M,Ditonno P

更新日期：2014-01-01 00:00:00

abstract：:Small bowel obstructions (SBOs) caused by adhesions are a common, often life-threatening postsurgical complication with few treatment options available for patients. This study examines the efficacy of a manual physical therapy treatment regimen on the pain and quality of life of subjects with a history of bowel obstr...

journal_title：BioMed research international

authors： Rice AD,Patterson K,Reed ED,Wurn BF,Klingenberg B,King CR 3rd,Wurn LJ

更新日期：2016-01-01 00:00:00

abstract：:Recent research had shown a correlation between aging and decreasing Gamma-aminobutyric acid (GABA), the primary inhibitory neurotransmitter in the brain. However, how GABA level varies with age in the medial portion of the brain has not yet been studied. The purpose of this study was to investigate the GABA level var...

journal_title：BioMed research international

authors： He X,Koo BB,Killiany RJ

更新日期：2016-01-01 00:00:00

abstract：:Ezrin, coding protein EZR which cross-links actin filaments, overexpresses and involves invasion, metastasis, and poor prognosis in various cancers including esophageal squamous cell carcinoma (ESCC). In our previous study, Ezrin was knock down and analyzed by mRNA expression profile which has not been fully mined. In...

journal_title：BioMed research international

authors： Wu B,Xie J,Du Z,Wu J,Zhang P,Xu L,Li E

更新日期：2014-01-01 00:00:00

abstract：:The three-dimensional (3D) structures of the right atrial appendage (RAA) and left atrial appendage (LAA) were compared to clarify why thrombus formation less frequently occurs in RAA than in LAA. Morphological differences between RAA and LAA of 34 formalin-preserved cadaver hearts were investigated. Molds of RAA and ...

journal_title：BioMed research international

authors： Shinoda K,Hayashi S,Fukuoka D,Torii R,Watanabe T,Nakano T

更新日期：2016-01-01 00:00:00

abstract：:Gedunin is one of the major compounds found in the neem tree (Azadirachta indica). In the present study, antiproliferative potential of gedunin was evaluated in human embryonal carcinoma cells (NTERA-2, a cancer stem cell model) and peripheral blood mononuclear cells (PBMCs), using Sulforhodamine (SRB) and WST-1 assay...

journal_title：BioMed research international

authors： Tharmarajah L,Samarakoon SR,Ediriweera MK,Piyathilaka P,Tennekoon KH,Senathilake KS,Rajagopalan U,Galhena PB,Thabrew I

更新日期：2017-01-01 00:00:00

abstract：:The mycotoxin zearalenone (ZEN) is a frequent contaminant of animal feeds, but its effects on fish have not yet been investigated extensively. In order to fill this gap a feeding trial with juvenile carp was conducted. Three groups of fish were fed feeds contaminated with ZEN at three concentrations (low: 332 μg kg(-1...

journal_title：BioMed research international

authors： Pietsch C,Junge R,Burkhardt-Holm P

更新日期：2015-01-01 00:00:00

abstract：:The incidence and rates of diagnosis of drug-induced liver injury (DILI) have been increasing in recent years as findings from basic research and the examination of clinical databases reveal information about the clinical course, etiology, and prognosis of this complex disease. The prevalence of metabolic comorbiditie...

journal_title：BioMed research international

authors： Li X,Gao P,Niu J

更新日期：2019-08-18 00:00:00

abstract：:Virulence-associated traits have frequently been studied in enterococci and are considered to contribute towards the pathogenicity of infections. In the present study, Enterococcus isolates were collected during diagnostic investigations from meat turkeys in Germany. Twenty-eight isolates of three different Enterococc...

journal_title：BioMed research international

authors： Maasjost J,Lüschow D,Kleine A,Hafez HM,Mühldorfer K

更新日期：2019-10-30 00:00:00

abstract：:Malaria is one of the life-threatening diseases in the world. The spread of resistance to antimalarial drugs is a major challenge, and resistance to artemisinin has been reported in the Southeast Asian region. In the previous study, the active compound of Streptomyces hygroscopicus subsp. Hygroscopicus (S. hygroscopic...

journal_title：BioMed research international

authors： Nugraha RY,Faratisha IF,Mardhiyyah K,Ariel DG,Putri FF,Nafisatuzzamrudah,Winarsih S,Sardjono TW,Fitri LE

更新日期：2020-01-09 00:00:00

abstract：Background:Osteonecrosis of the femoral head (ONFH) is a challenge for surgeons and is still without effective treatment method. This study is aimed at evaluating the combined pharmacotherapy with alendronate and desferoxamine for preventing glucocorticoid-induced osteonecrosis of the femoral head (GIOFH) and evaluatin...

journal_title：BioMed research international

authors： Sheng H,Lao Y,Zhang S,Ding W,Lu D,Xu B

更新日期：2020-09-21 00:00:00

abstract：:Hypertrophic Scars (HTSs) are a complex fibroproliferative disorder, and their exact mechanism is still not fully understood. In this study, we first found that cystic fibrosis transmembrane conductance regulator (CFTR) expression was downregulated in human hypertrophic scars at the RNA and protein levels by microarra...

journal_title：BioMed research international

authors： Zhou Y,Zhao Y,Du H,Suo Y,Chen H,Li H,Liang X,Li Q,Huang X

更新日期：2020-01-02 00:00:00

abstract：:Somatostatin (SST) receptors (SSTRs) belong to the typical 7-transmembrane domain family of G-protein-coupled receptors. Five distinct subtypes (termed SSTR1-5) have been identified, with SSTR2 showing the highest affinity for natural SST and synthetic SST analogs. Most neuroendocrine tumors (NETs) have high expressio...

journal_title：BioMed research international

authors： Xu C,Zhang H

更新日期：2015-01-01 00:00:00

abstract：:Although studies have shown that human migration is one of the risk factors for the spread of drug-resistant organisms such as methicillin-resistant Staphylococcus aureus (MRSA), surveillance studies examining MRSA among refugee populations in the US are lacking. This study aimed to assess the prevalence and molecular...

journal_title：BioMed research international

authors： Kadariya J,Thapaliya D,Bhatta S,Mahatara RL,Bempah S,Dhakal N,Smith TC

更新日期：2019-07-01 00:00:00

abstract：:Objective. The purpose of this study was to (i) determine the cervical microbial composition in different abortion samples and to (ii) investigate the correlation between spontaneous abortion and cervical microbes in Korean women. Methods. We collected cervical swabs from women who had never undergone abortion (N = 36...

journal_title：BioMed research international

authors： Seo SS,Arokiyaraj S,Kim MK,Oh HY,Kwon M,Kong JS,Shin MK,Yu YL,Lee JK

更新日期：2017-01-01 00:00:00