Abstract：
:Rhomboids are conserved intramembrane serine proteases with widespread functions. They were the earliest discovered members of the wider rhomboid-like superfamily of proteases and pseudoproteases. The secretase class of rhomboid proteases, distributed through the secretory pathway, are the most numerous in eukaryotes, but our knowledge of them is limited. Here we aim to summarise all that has been published on secretase rhomboids in a concise encyclopaedia of the enzymes, their substrates, and their biological roles. We also discuss emerging themes of how these important enzymes are regulated.
journal_name
Semin Cell Dev Bioljournal_title
Seminars in cell & developmental biologyauthors
Lastun VL,Grieve AG,Freeman Mdoi
10.1016/j.semcdb.2016.07.033subject
Has Abstractpub_date
2016-12-01 00:00:00pages
10-18eissn
1084-9521issn
1096-3634pii
S1084-9521(16)30237-3journal_volume
60pub_type
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journal_title：Seminars in cell & developmental biology
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journal_title：Seminars in cell & developmental biology
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