Abstract:
BACKGROUND:Psychoeducation is an effective adjunct to medications in bipolar disorder (BD). Brief psychoeducational approaches have been shown to improve early identification of relapse. However, the optimal method of delivery of psychoeducation remains uncertain. Here, our objective was to compare a short therapist-facilitated vs. self-directed psychoeducational intervention for BD. METHODS:BD outpatients who were receiving medication-based treatment were randomly assigned to 5 psychoeducation sessions administered by a therapist (Facilitated Integrated Mood Management; FIMM; n=60), or self-administered psychoeducation (Manualized Integrated Mood Management; MIMM; n=61). Follow-up was based on patients' weekly responses to an electronic mood monitoring programme over 12 months. RESULTS:Over follow-up, there were no group differences in weekly self-rated depression symptoms or relapse/readmission rates. However, knowledge of BD (assessed with the Oxford Bipolar Knowledge questionnaire (OBQ)) was greater in the FIMM than the MIMM group at 3 months. Greater illness knowledge at 3 months was related to a higher proportion of weeks well over 12 months. LIMITATIONS:Features of the trial may have reduced the sensitivity to our psychoeducation approach, including that BD participants had been previously engaged in self-monitoring. CONCLUSIONS:Improved OBQ score, while accelerated by a short course of therapist-administered psychoeducation (FIMM), was seen after both treatments. It was associated with better outcome assessed as weeks well. When developing and testing a new psychosocial intervention, studies should consider proximal outcomes (e.g., acquired knowledge) and their short-term impact on illness course in bipolar disorder.
journal_name
J Affect Disordjournal_title
Journal of affective disordersauthors
Bilderbeck AC,Atkinson LZ,McMahon HC,Voysey M,Simon J,Price J,Rendell J,Hinds C,Geddes JR,Holmes E,Miklowitz DJ,Goodwin GMdoi
10.1016/j.jad.2016.06.064subject
Has Abstractpub_date
2016-11-15 00:00:00pages
245-251eissn
0165-0327issn
1573-2517pii
S0165-0327(16)30770-4journal_volume
205pub_type
杂志文章,随机对照试验abstract:OBJECTIVES:Few studies have examined domain-specific psychosocial functioning in Bipolar Disorder (BD) youths. This prospective study examines (1) Interpersonal Relationships with Family; (2) Interpersonal Relationships with Friends; (3) School/Work; (4) Recreation; (5) Life Satisfaction, in BD youths. METHOD:A Course...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2020.03.016
更新日期:2020-05-01 00:00:00
abstract::Daytime plasma cortisol levels in four rapid cycling bipolar affective disorder patients were measured longitudinally over multiple affective episodes, and changes in levels with mood state assessed for each individual patient. While three of the four patients had, as expected, increased cortisol levels during depress...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/0165-0327(87)90054-1
更新日期:1987-01-01 00:00:00
abstract:BACKGROUND:Ketamine and its enantiomers have recently been highlighted as one of the most effective therapeutic options in refractory depression. However, racemic ketamine and esketamine have not been directly compared. The aim of this study is to assess the efficacy and safety of esketamine compared to ketamine in pat...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2019.11.086
更新日期:2020-03-01 00:00:00
abstract:BACKGROUND:Current data indicate a strong association between Cyclothymic temperament (and its more ultradian counterpart of mood lability) and Bipolar II (BPII). Administration of elaborate measures of temperament are cumbersome in routine practice. Accordingly, the aim of the present analyses was to test if a practic...
journal_title:Journal of affective disorders
pub_type: 评论,杂志文章
doi:10.1016/j.jad.2003.09.010
更新日期:2005-02-01 00:00:00
abstract:BACKGROUND:The relationship between temperament and sexual orientation has been poorly characterized. We have used the Affective and Emotional Composite Temperament (AFECT) model to evaluate this association in a large population sample. METHODS:Data from 16,571 subjects between 21 and 45 years old (mean age=29.1±6.3 ...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2015.01.029
更新日期:2015-04-01 00:00:00
abstract::We evaluated learning and memory in 50 depressed patients prior to and following 4 week treatment with imipramine compared to 21 normal controls tested at corresponding times. At baseline, the depressives did worse than normals on most memory tasks with the difficult memory tasks, regardless of store, modality or type...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/0165-0327(91)90038-t
更新日期:1991-03-01 00:00:00
abstract:BACKGROUND:Recent studies on the pathophysiology of major depression (MD) indicate that degenerative and inflammatory processes may play a role. This finding is supported by magnetic resonance imaging (MRI)-based meta-analysis that show volume reductions in circumscribed areas of the brain in patients with MD. Using op...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2017.11.077
更新日期:2018-02-01 00:00:00
abstract:OBJECTIVE:Depression after stroke (DAS) is a serious complication of stroke that significantly restricts rehabilitation. Brain imaging technology is an important method for studying the emotional network of DAS. However, few studies have focused on dynamic interactions within the network. The aim of this study was to i...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2019.02.020
更新日期:2019-04-15 00:00:00
abstract:BACKGROUND:Hypothalamic-pituitary-adrenal (HPA) axis dysregulation has been reported in bipolar disorder (BD), but previous magnetic resonance imaging (MRI) studies of pituitary gland volume in BD have yielded inconsistent findings. In addition, the contribution of genetic factors to the pituitary changes in BD remains...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2009.12.002
更新日期:2010-08-01 00:00:00
abstract:BACKGROUND:Central banks set economy-wide interest rates to meet exclusively economic objectives. There is a strong link between indebtedness and psychiatric morbidity at the individual level, with interest rates being an important factor determining ability to repay debt. However, no prior research has explored whethe...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2018.03.003
更新日期:2018-07-01 00:00:00
abstract::Electrodermal hyporeactivity in the anticipation of aversive stimuli is a highly reliable correlate of diagnosed psychopathy and undersocialized aggressive conduct disorder (UACD), and it has been interpreted as reflecting a weak behavioral inhibition system (BIS) as conceptualized in Gray's work (e.g., in: Royce, J.R...
journal_title:Journal of affective disorders
pub_type: 杂志文章,评审
doi:10.1016/s0165-0327(00)00336-0
更新日期:2000-12-01 00:00:00
abstract::Twenty inpatients suffering from an adjustment disorder with depressed mood according to the DSM-III criteria were compared with 22 inpatients with a (situationally provoked) major depression without an additional DSM-III/axis I diagnosis, with regard to expert- and self-rated symptomatology, social dysfunction and pe...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/0165-0327(89)90004-9
更新日期:1989-11-01 00:00:00
abstract:BACKGROUND:The aim was to examine the prevalence and consequences of co-occurring insomnia and hypersomnia symptoms in depressed adults drawn from a representative sample of the U.S. population. METHOD:Data from 687 National Comorbidity Survey Replication (NCS-R) respondents meeting criteria for a major depressive epi...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2014.05.060
更新日期:2014-01-01 00:00:00
abstract:BACKGROUND:Patients with major depressive disorder (MDD) show neuropsychological impairments, including deficient executive functions and altered sensitivity to reward and punishment. METHODS:Executive functions (Wisconsin Card Sorting Test, WCST) and contingency learning based on the cumulative effect of reward and p...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2005.12.005
更新日期:2006-02-01 00:00:00
abstract:BACKGROUND:Repetitive transcranial magnetic stimulation (rTMS) has shown efficacy in resistant unipolar depression, but its efficacy in bipolar disorders has not yet been extensively investigated. Mixed episodes are reported in up to 40% of acute bipolar admissions and are associated with severe psychopathology, comorb...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2013.12.024
更新日期:2014-03-01 00:00:00
abstract:BACKGROUND:Asthma is associated with multiple psychiatric comorbidities. However, the relationship between asthma and suicidality has not be well established. METHODS:According to the PRISMA guidelines, protocol of the study was registered in the PROSPERO database (CRD42019123150). A systematic search of the PubMed, E...
journal_title:Journal of affective disorders
pub_type: 杂志文章,meta分析
doi:10.1016/j.jad.2019.06.031
更新日期:2019-09-01 00:00:00
abstract:BACKGROUND:Recent studies have suggested that eating and sleep problems during early childhood may pose as risk factors for mood and anxiety disorders in later life. We aim to study the associations between early childhood sleep and eating problems, specifically high motor activity during sleep and irregularities in sl...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2006.05.025
更新日期:2006-11-01 00:00:00
abstract:BACKGROUND:Little is known about the extent to which manic symptoms might influence the self-report ratings of adolescents as compared to parent and teacher ratings, although there are clinical reasons to believe that mania would increase disagreement. METHODS:Parents and youths between the ages of 11 and 17 years wer...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2004.05.016
更新日期:2004-10-01 00:00:00
abstract:BACKGROUND:This study aimed to test the validity of using the Hypomania Checklist-16 [HCL-16] to measure hypomania in a British adolescent community sample. Limited research is available concerning the characterization of hypomania among community adolescent samples, particularly in the UK, despite its potential import...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2016.08.033
更新日期:2017-01-01 00:00:00
abstract:BACKGROUND:The diagnosis of mania largely depends on the quality of information the physician is provided with. Often, the patient cannot give an accurate account of the symptom development and thus information from relatives and friends is required. No systematic rating instrument is available, however, to facilitate ...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2009.07.022
更新日期:2010-04-01 00:00:00
abstract:BACKGROUND:Cardiorespiratory fitness (CRF) strongly influences health, but very little is known about the childhood determinants of adult CRF. Our longitudinal study investigated whether childhood psychopathology and socioeconomic status (SES) were related to adult CRF in 1647 Finnish male military conscripts. METHODS...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2019.11.029
更新日期:2020-04-01 00:00:00
abstract::Using multiple variables of illness, comparisons were made between 17 postpartum depressives with recurrent affective disorder and 37 women with children and recurrent affective disorder but no postpartum depressions. An earlier age of onset in patients with postpartum depression was the only variable that was signifi...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/0165-0327(83)90002-2
更新日期:1983-05-01 00:00:00
abstract:BACKGROUND:Bipolar disorder (BD) is associated with inhibitory deficits characterized by a reduced ability to control inappropriate actions or thoughts. While aspects of inhibition such as exaggerated novelty-seeking and perseveration are quantified in rodent exploration of novel environments, similar models are rarely...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2013.05.020
更新日期:2013-09-25 00:00:00
abstract::Studies of patients' attitudes towards lithium treatment are reviewed. In the present work, a brief questionnaire was developed as a means of identifying and grouping the problems patients commonly have with taking lithium regularly. This 'Lithium Attitudes Questionnaire' was found to yield consistent results which pa...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/0165-0327(91)90067-3
更新日期:1991-08-01 00:00:00
abstract:BACKGROUND:In the new global socioeconomic development, suicidal deaths have increased which is progressively gaining more attention in the field of psychiatry, social work, psychology, and public health research. The present study aimed at examining the evidence for the attitudes towards suicide and risk factors for s...
journal_title:Journal of affective disorders
pub_type: 杂志文章,评审
doi:10.1016/j.jad.2020.03.135
更新日期:2020-07-01 00:00:00
abstract:BACKGROUND:Invariant item ordering (IIO) is defined as the extent to which items have the same ordering (in terms of item difficulty/severity - i.e. demonstrating whether items are difficult [rare] or less difficult [common]) for each respondent who completes a scale. IIO is therefore crucial for establishing a scale h...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2011.10.022
更新日期:2012-06-01 00:00:00
abstract:BACKGROUND:Our aim was to examine associations between depression and time spent in TV viewing in a representative sample of Brazilian adults. METHODS:Data from the Brazilian National Health Survey (Pesquisa Nacional de Saúde - PNS in Portuguese) (n =60,202; ≥18 years) were used. Time spent TV viewing (h/day) was elic...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2018.04.083
更新日期:2018-08-15 00:00:00
abstract:STUDY OBJECTIVE:The aim of this preliminary study is to investigate the regional blood flow in response to ECT (electroconvulsive therapy) and to identify any responsive-pattern to the treatment. METHODS: STUDY DESIGN:Single longitudinal prospective study of cohorts. SUBJECTS:For this preliminary study ten patients,...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/s0165-0327(00)00200-7
更新日期:2001-06-01 00:00:00
abstract:BACKGROUND:Major Depressive Disorder (MDD) is the 3rd source for burden worldwide according to the World Health Organization (WHO). This comes partly from unsatisfactory response rates after usual treatment, highlighting the need for early indicators such as early improvement of depressive symptoms to adapt treatment s...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2014.03.002
更新日期:2014-06-01 00:00:00
abstract:BACKGROUND:This study examined dissociation, shame, guilt and intimate relationship difficulties in those with chronic and complex PTSD. Little is known about how these symptom clusters interplay within the complex PTSD constellation. Dissociation was examined as a principle organizing construct within complex PTSD. In...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2012.10.010
更新日期:2013-05-01 00:00:00