Abstract：
:We evaluated learning and memory in 50 depressed patients prior to and following 4 week treatment with imipramine compared to 21 normal controls tested at corresponding times. At baseline, the depressives did worse than normals on most memory tasks with the difficult memory tasks, regardless of store, modality or type of task best distinguishing between depressive and normal memory. Following imipramine treatment, responders performed better than nonresponders on the difficult memory tasks, and not significantly differently from controls on most tasks. This, as well as the fact that the responders improved to a greater degree than controls on most measures (in a few cases the difference was statistically significant) and the fact that at 4 weeks complete responders to imipramine did significantly better than partial responders to imipramine, indicates that relief from depression is highly related to improved memory functioning. The finding that complete responders to imipramine were not significantly worse than normal controls suggests that imipramine did not have significant adverse effects on memory.
journal_name
J Affect Disordjournal_title
Journal of affective disordersauthors
Peselow ED,Corwin J,Fieve RR,Rotrosen J,Cooper TBdoi
10.1016/0165-0327(91)90038-tsubject
Has Abstractpub_date
1991-03-01 00:00:00pages
173-83issue
3eissn
0165-0327issn
1573-2517pii
0165-0327(91)90038-Tjournal_volume
21pub_type
杂志文章abstract：BACKGROUND:Bipolar disorder (BPD) is a disabling disease with high morbidity rates. An international (Spain, France) comparative study about hospitalizations and in-patient care costs associated with BPD I was performed. Centers were included if they had access to a database of computerized patient charts exhaustively ...
journal_title：Journal of affective disorders
pub_type： 杂志文章
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更新日期：2010-02-01 00:00:00
abstract：:Thyrotropin secreting hormone (TSH) levels were recorded in baseline conditions and 20 and 60 min after thyrotropin releasing hormone (TRH) administration (200 micrograms i.v.) in 60 depressed females categorized according to DSM-III. Basal TSH (TSHB) and peak TSH responses (TSHP) were measured using ultrasensitive RI...
journal_title：Journal of affective disorders
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更新日期：1989-03-01 00:00:00
abstract：BACKGROUND:Ketamine appears to have a therapeutic role in certain mental disorders, most notably depression. However, the comparative performance of different formulations of ketamine is less clear. OBJECTIVES:This study aimed to assess the comparative efficacy and tolerability of racemic and esketamine for the treatm...
journal_title：Journal of affective disorders
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更新日期：2021-01-01 00:00:00
abstract：BACKGROUND:The prevalence of antidepressant prescribing in children and adolescents increased steadily in the United States and parts of Europe between 2005 and 2012 despite regulatory safety warnings. Little is known about the characteristics of those being prescribed antidepressants for the first time. METHODS:A lon...
journal_title：Journal of affective disorders
pub_type： 杂志文章
doi：10.1016/j.jad.2016.12.047
更新日期：2017-03-01 00:00:00
abstract：OBJECTIVE:The frontal-limbic circuit is hypothesized as sub-serving emotional regulation. We performed whole brain resting-state functional connectivity (rs-FC) analysis by studying the key hubs of frontal-limbic circuit: anterior cingulate cortex (ACC), bilateral insula subregions, bilateral amygdala (Amy) as seeds, s...
journal_title：Journal of affective disorders
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更新日期：2020-09-01 00:00:00
abstract：:The aim of this study was to investigate the concurrent validity of the French language version of the Calgary Depression Scale for Schizophrenics (CDSS). Ninety-five schizophrenic patients meeting the DSM-III-R criteria were enrolled in the study. The depressive symptoms were evaluated using the Calgary Depression Sc...
journal_title：Journal of affective disorders
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更新日期：2000-05-01 00:00:00
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journal_title：Journal of affective disorders
pub_type： 杂志文章
doi：10.1016/j.jad.2009.08.017
更新日期：2010-06-01 00:00:00
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journal_title：Journal of affective disorders
pub_type： 杂志文章
doi：10.1016/j.jad.2020.11.093
更新日期：2021-02-15 00:00:00
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journal_title：Journal of affective disorders
pub_type： 杂志文章
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更新日期：2011-06-01 00:00:00
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journal_title：Journal of affective disorders
pub_type： 杂志文章
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更新日期：2016-03-01 00:00:00
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journal_title：Journal of affective disorders
pub_type： 杂志文章
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更新日期：1992-10-01 00:00:00
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journal_title：Journal of affective disorders
pub_type： 杂志文章
doi：10.1016/j.jad.2016.04.041
更新日期：2016-08-01 00:00:00
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journal_title：Journal of affective disorders
pub_type： 杂志文章
doi：10.1016/s0165-0327(99)00044-0
更新日期：1999-12-01 00:00:00
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journal_title：Journal of affective disorders
pub_type： 临床试验,杂志文章,随机对照试验
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更新日期：1993-02-01 00:00:00
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journal_title：Journal of affective disorders
pub_type： 杂志文章,多中心研究,随机对照试验
doi：10.1016/j.jad.2008.01.009
更新日期：2008-10-01 00:00:00
abstract：BACKGROUND:Symptoms of grief vary by culture and societal reactions to death may be gender specific. We aimed to validate a Nepali language version of the Prolonged Grief-13 item scale (PG-13) among widows. METHODS:We tested two adapted versions of a Prolonged Grief Disorder (PGD) instrument with 204 Nepali-speaking w...
journal_title：Journal of affective disorders
pub_type： 杂志文章
doi：10.1016/j.jad.2020.12.018
更新日期：2021-02-15 00:00:00
abstract：:Prior to 1970, childhood depression was not considered a valid clinical entity by American psychiatrists. One of the early clues was provided in the 1950s by the author's observation of depressive symptoms in children and young adolescents with undescended testicles. This finding was extended to children with several ...
journal_title：Journal of affective disorders
pub_type： 历史文章,杂志文章
doi：10.1016/s0165-0327(03)00048-x
更新日期：2003-10-01 00:00:00
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journal_title：Journal of affective disorders
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更新日期：2013-09-25 00:00:00
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pub_type： 杂志文章
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更新日期：2012-12-10 00:00:00
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journal_title：Journal of affective disorders
pub_type： 杂志文章
doi：10.1016/j.jad.2018.01.013
更新日期：2018-04-15 00:00:00
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journal_title：Journal of affective disorders
pub_type： 杂志文章
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更新日期：1993-12-01 00:00:00
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journal_title：Journal of affective disorders
pub_type： 杂志文章
doi：10.1016/j.jad.2009.12.002
更新日期：2010-08-01 00:00:00
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journal_title：Journal of affective disorders
pub_type： 杂志文章,评审
doi：10.1016/j.jad.2016.10.035
更新日期：2017-12-15 00:00:00
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journal_title：Journal of affective disorders
pub_type： 杂志文章,meta分析
doi：10.1016/j.jad.2018.12.008
更新日期：2019-02-15 00:00:00
abstract：BACKGROUND:According to published reports, the prevalence rates of major depressive disorder (MDD) in East-Asian countries are lower than in the West, but the reasons for this difference have not been fully investigated. METHODS:This study compared the Korean Epidemiologic Catchment Area study (KECAS) sample with the ...
journal_title：Journal of affective disorders
pub_type： 杂志文章
doi：10.1016/j.jad.2007.07.023
更新日期：2008-02-01 00:00:00
abstract：BACKGROUND:Conventional surveillance systems for suicides typically suffer from a substantial time lag of six months to two years. This study aims to develop an early warning system of possible suicide outbreaks in Hong Kong using Google Trends and suicide-related media reporting. METHODS:Data on 3,534 suicides from 2...
journal_title：Journal of affective disorders
pub_type： 杂志文章
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更新日期：2019-08-01 00:00:00
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journal_title：Journal of affective disorders
pub_type： 临床试验,杂志文章,随机对照试验
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更新日期：1999-08-01 00:00:00
abstract：INTRODUCTION:Many studies of patients with major depression have reported that a significant decrease in serum free T(4) index is associated with specific treatments; what has been unanswered is whether these observations are generalizable. This study evaluated baseline thyroid function and its relationship to rapidity...
journal_title：Journal of affective disorders
pub_type： 杂志文章
doi：10.1016/j.jad.2006.10.012
更新日期：2007-06-01 00:00:00
abstract：UNLABELLED:Biased inhibitory processing, frequency and valence of automatic thoughts, and inability to use positive schemas to regulate negative mood are cognitive factors linked to depression. These processes may underlie the established link between adaptive cognitive coping strategies (acceptance and positive refram...
journal_title：Journal of affective disorders
pub_type： 杂志文章
doi：10.1016/j.jad.2013.05.014
更新日期：2013-09-25 00:00:00
abstract：BACKGROUND:Heightened threat sensitivity is a transdiagnostic feature in several psychiatric disorders. The neuropeptide oxytocin has been shown to reduce fear related behaviours and facilitated fear extinction in animals. These findings have led to increasing interest to explore the effects of intranasal oxytocin on t...
journal_title：Journal of affective disorders
pub_type： 杂志文章,meta分析,评审
doi：10.1016/j.jad.2017.08.041
更新日期：2018-01-01 00:00:00
