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Cerebral blood flow in major depression and dysthymia.

Abstract：

:Using single photon emission computerized tomography (SPECT) with a 99mTc-HMPAO perfusion technique, we studied the regional cerebral blood flow (rCBF) of 42 drug-free inpatients suffering from Major Depression' (n = 21) or dysthymia with the super-imposed diagnosis of a major depressive episode (n = 21). The patients with Major Depression had a significantly lower frontal and posterior rCBF ratio than those with Double Depression. Left frontal region indices showed a slight overlap between the two groups. There was no correlation between the severity of the illness and the rCBF indices. Different qualitative cerebral dysfunctions may be implicated in these two affective disorder sub-types.

journal_name

J Affect Disord

journal_title

Journal of affective disorders

authors

Thomas P,Vaiva G,Samaille E,Maron M,Alaix C,Steinling M,Goudemand M

doi

10.1016/0165-0327(93)90013-a

subject

Has Abstract

pub_date

1993-12-01 00:00:00

pages

235-42

issue

4

eissn

0165-0327

issn

1573-2517

pii

0165-0327(93)90013-A

journal_volume

29

pub_type

杂志文章

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