当前位置： SCI文献检索 > JOURNAL OF AFFECTIVE DISORDERS期刊下所有文献 > The impact of somatic symptoms on the course of major depressive disorder.

The impact of somatic symptoms on the course of major depressive disorder.

Abstract：

OBJECTIVE:Somatic symptoms have been suggested to negatively affect the course of major depressive disorder (MDD). Mechanisms behind this association, however, remain elusive. This study examines the impact of somatic symptoms on MDD prognosis and aims to determine whether this effect can be explained by psychiatric characteristics, somatic diseases, lifestyle factors, and disability. METHODS:In 463 MDD patients (mean age=44.9 years, 69.8% female) from the Netherlands Study of Depression and Anxiety (NESDA), we examined whether the type and number of somatic symptom clusters predicted the two-year persistence of MDD. Diagnoses of MDD were established with the Composite International Diagnostic Interview (CIDI) and somatic symptom clusters were assessed with the Four-Dimensional Symptom Questionnaire (4DSQ) somatization scale. Psychiatric characteristics, somatic diseases, lifestyle factors, and disability were taken into account as factors potentially underlying the association. RESULTS:The cardiopulmonary, gastrointestinal, and general cluster significantly predicted the two-year persistence of MDD, but only when two or more of these clusters were present (OR=2.32, 95% CI=1.51-3.57, p=<0.001). Although the association was partly explained by MDD severity, the presence of multiple somatic symptom clusters remained a significant predictor after considering all potentially underlying factors (OR=1.69, 95%CI=1.07-2.68, p=0.03). CONCLUSIONS:Somatic symptoms are predictors of a worse prognosis of MDD independent of psychiatric characteristics, somatic diseases, lifestyle factors, and disability. These results stress the importance of considering somatic symptoms in the diagnostic and treatment trajectory of patients with MDD. Future research should focus on identifying treatment modalities targeting depressive as well as somatic symptoms.

journal_name

J Affect Disord

journal_title

Journal of affective disorders

authors

Bekhuis E,Boschloo L,Rosmalen JG,de Boer MK,Schoevers RA

doi

10.1016/j.jad.2016.06.030

subject

Has Abstract

pub_date

2016-11-15 00:00:00

pages

112-118

eissn

0165-0327

issn

1573-2517

pii

S0165-0327(16)30341-X

journal_volume

205

pub_type

杂志文章

相关文献

JOURNAL OF AFFECTIVE DISORDERS文献大全
  • Relative lack of depressive cognitions in post-myocardial infarction depression.

    abstract：BACKGROUND:Depression has been associated with adverse clinical events in myocardial infarction (MI) patients, but many questions about the nature of post-MI depression remain unanswered. We examined whether depressive cognitions characteristic of depression in psychiatric patients are also present in post-MI patients ...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/j.jad.2006.04.023

    authors： Martens EJ,Denollet J,Pedersen SS,Scherders M,Griez E,Widdershoven J,Szabó B,Bonnier H,Appels A

    更新日期：2006-08-01 00:00:00

  • Augmenting psychoeducation with a mobile intervention for bipolar disorder: a randomized controlled trial.

    abstract：BACKGROUND:Psychosocial interventions for bipolar disorder are frequently unavailable and resource intensive. Mobile technology may improve access to evidence-based interventions and may increase their efficacy. We evaluated the feasibility, acceptability and efficacy of an augmentative mobile ecological momentary inte...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章,随机对照试验

    doi：10.1016/j.jad.2014.10.053

    authors： Depp CA,Ceglowski J,Wang VC,Yaghouti F,Mausbach BT,Thompson WK,Granholm EL

    更新日期：2015-03-15 00:00:00

  • A prospective, open-label study of Aripiprazole mono- and adjunctive treatment in acute bipolar depression.

    abstract：OBJECTIVE:To examine the efficacy and tolerability of aripiprazole treatment for acute bipolar depression. METHODS:A six-week prospective, nonrandomized, open label study was conducted in depressed bipolar outpatients (types I, II, and NOS), as diagnosed by DSM-IV criteria. Previous treatments were continued unchanged...

    journal_title：Journal of affective disorders

    pub_type： 临床试验,杂志文章

    doi：10.1016/j.jad.2008.01.004

    authors： Dunn RT,Stan VA,Chriki LS,Filkowski MM,Ghaemi SN

    更新日期：2008-09-01 00:00:00

  • Are attitudes towards emotions associated with depression? A Conceptual and meta-analytic review.

    abstract：OBJECTIVES:We performed a conceptual and meta-analytic review of the relationship between negative cognitive and affective evaluations of negative emotional experiences (negative ATE) and depression. We examined the negative ATE-depression relationship in terms of three ATE constructs: fear of emotion, non-acceptance o...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章,meta分析,评审

    doi：10.1016/j.jad.2018.02.009

    authors： Yoon S,Dang V,Mertz J,Rottenberg J

    更新日期：2018-05-01 00:00:00

  • Associations of Body Weight and Waist Circumference with Psychopathology, Substance Use, and Well-Being in an Adult Transdiagnostic Sample.

    abstract：BACKGROUND:Prior studies have established inconsistent associations between body weight and mental health. However, most work has relied on body mass index (BMI) and examination of a single mental health variable. The present study examined associations of BMI and waist circumference with multiple mental health variabl...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/j.jad.2020.12.029

    authors： Yusufov M,Kopeski LM,Silverman AL,Björgvinsson T

    更新日期：2021-02-15 00:00:00

  • Early risk factors for postpartum depression: A longitudinal Japanese population-based study.

    abstract：BACKGROUND:Postpartum depression (PPD) negatively impacts maternal health, parenting and development of children. Most previous studies on PPD risk factors are based on Western populations. Additionally, little is known about the association between psychosocial factors during early pregnancy period and PPD. We aimed t...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/j.jad.2020.03.026

    authors： Nakano M,Sourander A,Luntamo T,Chudal R,Skokauskas N,Kaneko H

    更新日期：2020-05-15 00:00:00

  • The utility of the combination of dextromethorphan and quinidine in the treatment of bipolar II and bipolar NOS.

    abstract：BACKGROUND:Dextromethorphan is an over-the-counter antitussive agent that may be a rapidly acting treatment for bipolar depression. Like ketamine, it is an NMDA receptor antagonist. METHODS:We conducted a retrospective chart review of depressed patients with treatment resistant bipolar II or bipolar NOS disorder who w...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/j.jad.2014.05.050

    authors： Kelly TF,Lieberman DZ

    更新日期：2014-01-01 00:00:00

  • Lack of a relationship between the pupillary light reflex response and state/trait anxiety in remitted patients with panic disorder.

    abstract：OBJECTIVE:Recently, some studies have indicated that pupillary function only correlates with state/trait anxiety in healthy subjects. In the present study, we examined whether or not there were relationships between the PLR functions and state/trait anxiety in remitted (the absence of panic attack (PA) symptoms for at ...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/j.jad.2006.04.031

    authors： Shioiri T,Kuwabara H,Abe R,Iijima A,Kojima-Maruyama M,Kitamura H,Bando T,Someya T

    更新日期：2006-10-01 00:00:00

  • Identification of the neural correlates of cyclothymic temperament using an esthetic judgment for paintings task in fMRI.

    abstract：BACKGROUND:There is a well-known association between artistic creativity and cyclothymic temperament but the neural correlates of cyclothymic temperament have not yet been fully identified. Recently, we showed that the left lingual gyrus and bilateral cuneus may be associated with esthetic judgment of representational ...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/j.jad.2014.07.037

    authors： Mizokami Y,Terao T,Hatano K,Kodama K,Kohno K,Makino M,Hoaki N,Araki Y,Izumi T,Shimomura T,Fujiki M,Kochiyama T

    更新日期：2014-12-01 00:00:00

  • A double blind randomized trial of unilateral left and bilateral prefrontal cortex transcranial magnetic stimulation in treatment resistant major depression.

    abstract：OBJECTIVE:A substantive body of research has demonstrated the efficacy of repetitive transcranial magnetic stimulation treatment (rTMS) in patients with depression. However, the parameters needed to optimize therapeutic efficacy remain unclear. The aim of this study was to investigate whether there is an advantage in e...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章,随机对照试验

    doi：10.1016/j.jad.2012.02.017

    authors： Fitzgerald PB,Hoy KE,Herring SE,McQueen S,Peachey AV,Segrave RA,Maller J,Hall P,Daskalakis ZJ

    更新日期：2012-07-01 00:00:00

  • Sociodemographic, clinical, and attitudinal characteristics of the untreated depressed in Ontario.

    abstract：BACKGROUND:Epidemiologic surveys consistently document high rates of untreated depression, yet why this unmet need exists is only partially understood. METHODS:We compared untreated depressed, treated depressed and "healthy" subjects on sociodemographic characteristics, need for treatment, and help-seeking attitudes u...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/s0165-0327(98)00116-5

    authors： Lin E,Parikh SV

    更新日期：1999-05-01 00:00:00

  • A three-year longitudinal study of affective temperaments and risk for psychopathology.

    abstract：BACKGROUND:Affective temperaments are presumed to underlie bipolar psychopathology. The TEMPS-A has been widely used to assess affective temperaments in clinical and non-clinical samples. Cross-sectional research supports the association of affective temperaments and mood psychopathology; however, longitudinal research...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/j.jad.2014.04.006

    authors： DeGeorge DP,Walsh MA,Barrantes-Vidal N,Kwapil TR

    更新日期：2014-08-01 00:00:00

  • Comorbidity of ADHD and suicide attempts among adolescents and young adults with bipolar disorder: A nationwide longitudinal study.

    abstract：BACKGROUND:Suicide is among the leading causes of death among people with bipolar disorder and has gained substantial attention in the psychiatric and public health fields. However, the role of attention deficit hyperactivity disorder (ADHD) in suicide among adolescents and young adults with bipolar disorder remains un...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/j.jad.2015.02.007

    authors： Lan WH,Bai YM,Hsu JW,Huang KL,Su TP,Li CT,Yang AC,Lin WC,Chang WH,Chen TJ,Tsai SJ,Chen MH

    更新日期：2015-05-01 00:00:00

  • Treatment-resistant depression and suicidality.

    abstract：BACKGROUND:Thirty percent of patients with treatment-resistant depression (TRD) attempt suicide at least once during their lifetime. However, it is unclear what the attempted and completed suicide incidences are in TRD patients after initiating a treatment, and whether specific treatments increase or decrease these inc...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章,评审

    doi：10.1016/j.jad.2018.04.016

    authors： Bergfeld IO,Mantione M,Figee M,Schuurman PR,Lok A,Denys D

    更新日期：2018-08-01 00:00:00

  • Depression-anxiety relationships with chronic physical conditions: results from the World Mental Health Surveys.

    abstract：BACKGROUND:Prior research on the association between affective disorders and physical conditions has been carried out in developed countries, usually in clinical populations, on a limited range of mental disorders and physical conditions, and has seldom taken into account the comorbidity between depressive and anxiety ...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章,多中心研究

    doi：10.1016/j.jad.2007.01.015

    authors： Scott KM,Bruffaerts R,Tsang A,Ormel J,Alonso J,Angermeyer MC,Benjet C,Bromet E,de Girolamo G,de Graaf R,Gasquet I,Gureje O,Haro JM,He Y,Kessler RC,Levinson D,Mneimneh ZN,Oakley Browne MA,Posada-Villa J,Stein DJ,Ta

    更新日期：2007-11-01 00:00:00

  • The effects of ethnic, social and cultural factors on axis I comorbidity of bipolar disorder: results from the clinical setting in Korea.

    abstract：OBJECTIVE:Ethnic, social and cultural factors contribute to axis I comorbid conditions in bipolar disorder (BPD). Korea has strict laws against illicit drugs and a relatively permissive prevailing attitude toward alcohol. The present study aimed to explore the lifetime axis I comorbidity rate in patients with BPD in Ko...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/j.jad.2014.05.027

    authors： Baek JH,Cha B,Moon E,Ha TH,Chang JS,Kim JH,Choi JE,Kang BJ,Hong KS,Ha K

    更新日期：2014-09-01 00:00:00

  • Dropout from randomised controlled trials of psychological treatments for depression in children and youth: a systematic review and meta-analyses.

    abstract：BACKGROUND:Depression is a prevalent and disabling condition in youth. Treatment efficacy has been demonstrated for several therapeutic modalities. Acceptability of treatments is also important to explore and was addressed by investigating treatment dropout using meta-analyses. METHODS:A systematic search was conducte...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章,评审

    doi：10.1016/j.jad.2020.11.039

    authors： Wright I,Mughal F,Bowers G,Meiser-Stedman R

    更新日期：2021-02-15 00:00:00

  • Is anxiety/depression increasing among 5-25 year-olds? A cross-sectional prevalence study in Ontario, Canada, 1997-2017.

    abstract：BACKGROUND:Self-reported data and media suggest youth mental health is declining. To more objectively measure this, we conducted a population-wide investigation of changes in diagnosed point prevalences of anxiety/depression among children and young adults between 1997 and 2017 in Ontario, Canada. METHODS:All Ontarian...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/j.jad.2020.12.178

    authors： Phillips SP,Yu J

    更新日期：2020-12-30 00:00:00

  • Chronic medical conditions and metabolic syndrome as risk factors for incidence of major depressive disorder: A longitudinal study based on 4.7 million adults in South Korea.

    abstract：BACKGROUND:The assessment of comorbid physical illness and metabolic or cardiovascular risk factors as potential risk factors for onset of major depressive disorder (MDD) is crucial. We aimed to investigate potential risk factors for the development of MDD among individuals with chronic medical conditions and metabolic...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/j.jad.2019.07.003

    authors： Han KM,Kim MS,Kim A,Paik JW,Lee J,Ham BJ

    更新日期：2019-10-01 00:00:00

  • The in vitro immunosuppressive effects of moclobemide in healthy volunteers.

    abstract：BACKGROUND:Many studies have demonstrated that major depression is related to an activation of the inflammatory response system (IRS) with an increased production of proinflammatory cytokines. It has been shown that tricyclic antidepressants and serotonin reuptake inhibitors suppress the activation of the IRS in depres...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/s0165-0327(99)00076-2

    authors： Lin A,Song C,Kenis G,Bosmans E,De Jongh R,Scharpé S,Maes M

    更新日期：2000-04-01 00:00:00

  • Psychosocial stress and anxiety in senile dementia.

    abstract：:Seventy dementia patients in hospital and two control groups comprising 50 dementia sufferers in the community and 50 mentally fit elderly people, were investigated to determine which social factors such as life events were associated with the presence of anxiety symptoms. Very high levels of social contact, problems ...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/0165-0327(95)00094-1

    authors： Orrell M,Bebbington P

    更新日期：1996-07-29 00:00:00

  • Psychometric properties of the concise health risk tracking (CHRT) in adolescents with suicidality.

    abstract：BACKGROUND:Several self-report rating scales have been developed to assess suicidal ideation, yet few examine other factors related to increased suicidal risk, and even fewer have been validated in both adolescents and adults. We evaluate the 14-item Concise Health Risk Tracking - Self Report (CHRT-SR), a measure previ...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/j.jad.2018.03.007

    authors： Mayes TL,Kennard BD,Killian M,Carmody T,Grannemann BD,Rush AJ,Jha MK,Hughes J,Emslie GJ,Trivedi MH

    更新日期：2018-08-01 00:00:00

  • Association between the TPH1 A218C polymorphism and risk of mood disorders and alcohol dependence: evidence from the current studies.

    abstract：BACKGROUND:Several studies have assessed the association between genetic polymorphisms of tryptophan hydroxylase (TPH1) and risk of mood disorders and alcohol dependence, with controversial results. Our aim was to assess the association of TPH1 A218C polymorphism (rs1800532) with mood disorders, including major depress...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章,meta分析

    doi：10.1016/j.jad.2011.04.018

    authors： Chen D,Liu F,Yang C,Liang X,Shang Q,He W,Wang Z

    更新日期：2012-04-01 00:00:00

  • The biological basis of anxiety. An overview.

    abstract：:The DSM-III divides anxiety disorders into two broad categories, Phobic Disorders and Anxiety States. Anxiety states characterised by panic attacks have been separated from generalised anxiety disorders. While this classification may not be generally accepted it is of heuristic value. Delineation of panic disorder as ...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/0165-0327(85)90058-8

    authors： Judd FK,Burrows GD,Norman TR

    更新日期：1985-11-01 00:00:00

  • Measurement invariance of assessments of depression (PHQ-9) and anxiety (GAD-7) across sex, strata and linguistic backgrounds in a European-wide sample of patients after Traumatic Brain Injury.

    abstract：BACKGROUND:The Patient Health Questionnaire-9 (PHQ-9) and the Generalized Anxiety Disorder (GAD-7) are two widely used instruments to screen patients for depression and anxiety. Comparable psychometric properties across different demographic and linguistic groups are necessary for multiple group comparison and internat...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/j.jad.2019.10.035

    authors： Teymoori A,Real R,Gorbunova A,Haghish EF,Andelic N,Wilson L,Asendorf T,Menon D,von Steinbüchel N

    更新日期：2020-02-01 00:00:00

  • What are the effects of preventative interventions on major depressive disorder (MDD) in young adults? A systematic review and meta-analysis of randomized controlled trials.

    abstract：BACKGROUND:Depression is a prevalent disorder with a peak rate of onset in young adulthood from 18 to 25 years. To date, no review has systematically assessed the effectiveness of programs that aim to reduce depressive symptoms or diagnosis of depression in young adults. METHOD:A systematic search was performed in Coc...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章,meta分析

    doi：10.1016/j.jad.2018.05.010

    authors： Breedvelt JJF,Kandola A,Kousoulis AA,Brouwer ME,Karyotaki E,Bockting CLH,Cuijpers P

    更新日期：2018-10-15 00:00:00

  • A reliability generalization meta-analysis of the child and adolescent perfectionism scale.

    abstract：BACKGROUND:Perfectionism is a prevalent disposition of personality involved in the development and maintenance of a wide range of psychological disorders. The Child and Adolescent Perfectionism Scale (CAPS) is the most usually applied test to assess perfectionism in children and adolescents. This study aimed: (a) to co...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章,meta分析,评审

    doi：10.1016/j.jad.2018.11.049

    authors： Vicent M,Rubio-Aparicio M,Sánchez-Meca J,Gonzálvez C

    更新日期：2019-02-15 00:00:00

  • Gender patterns in cost effectiveness of quality improvement for depression: results of a randomized, controlled trial.

    abstract：BACKGROUND:Little is known about gender differences in the costs and outcomes of primary care quality improvement strategies for depression. METHODS:Intent-to-treat analysis of data from a group-level controlled trial, in which matched primary care clinics in the US were randomized to usual care or to one of two inter...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章,随机对照试验

    doi：10.1016/j.jad.2005.03.018

    authors： Schoenbaum M,Sherbourne C,Wells K

    更新日期：2005-08-01 00:00:00

  • Antidepressant drug use in Lombardy, Italy: a population-based study.

    abstract：BACKGROUND:The patterns of antidepressant drug prescribing have rarely been studied in large and geographically defined catchment areas. In the present study, we examined the prevalence and distribution of antidepressant prescribing in Lombardy, a northern Italy region of nine million inhabitants. METHODS:This study u...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/j.jad.2004.07.005

    authors： Percudani M,Barbui C,Fortino I,Petrovich L

    更新日期：2004-12-01 00:00:00

  • Stroop performance in depressive patients: a preliminary report.

    abstract：BACKGROUND:The Stroop interference test requires executive control functions, in particular inhibition of a learned routine (in this case word reading). Depressive patients show deficits on tests of executive function. However, the impact of confounding variables like type of depression and anxiety level is not yet elu...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/j.jad.2006.04.011

    authors： Markela-Lerenc J,Kaiser S,Fiedler P,Weisbrod M,Mundt C

    更新日期：2006-08-01 00:00:00