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Depression-anxiety relationships with chronic physical conditions: results from the World Mental Health Surveys.

Abstract：

BACKGROUND:Prior research on the association between affective disorders and physical conditions has been carried out in developed countries, usually in clinical populations, on a limited range of mental disorders and physical conditions, and has seldom taken into account the comorbidity between depressive and anxiety disorders. METHODS:Eighteen general population surveys were carried out among adults in 17 countries as part of the World Mental Health Surveys initiative (N=42, 249). DSM-IV depressive and anxiety disorders were assessed using face-to-face interviews with the Composite International Diagnostic Interview (CIDI 3.0). Chronic physical conditions were ascertained via a standard checklist. The relationship between mental disorders and physical conditions was assessed by considering depressive and anxiety disorders independently (depression without anxiety; anxiety without depression) and conjointly (depression plus anxiety). RESULTS:All physical conditions were significantly associated with depressive and/or anxiety disorders but there was variation in the strength of association (ORs 1.2-4.5). Non-comorbid depressive and anxiety disorders were associated in equal degree with physical conditions. Comorbid depressive-anxiety disorder was more strongly associated with several physical conditions than were single mental disorders. LIMITATIONS:Physical conditions were ascertained via self report, though for a number of conditions this was self-report of diagnosis by a physician. CONCLUSIONS:Given the prevalence and clinical consequences of the co-occurrence of mental and physical disorders, attention to their comorbidity should remain a clinical and research priority.

journal_name

J Affect Disord

journal_title

Journal of affective disorders

authors

Scott KM,Bruffaerts R,Tsang A,Ormel J,Alonso J,Angermeyer MC,Benjet C,Bromet E,de Girolamo G,de Graaf R,Gasquet I,Gureje O,Haro JM,He Y,Kessler RC,Levinson D,Mneimneh ZN,Oakley Browne MA,Posada-Villa J,Stein DJ,Ta

doi

10.1016/j.jad.2007.01.015

subject

Has Abstract

pub_date

2007-11-01 00:00:00

pages

113-20

issue

1-3

eissn

0165-0327

issn

1573-2517

pii

S0165-0327(07)00017-1

journal_volume

103

pub_type

杂志文章,多中心研究

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