Abstract：
:One explanation for the association between mitral valve prolapse (MVP) and panic attacks in clinic populations is that panic attacks represent a set of symptoms caused by mitral prolapse. Since mitral prolapse is often familial, this hypothesis predicts a higher incidence of panic attacks in relatives of persons with prolapse than the general population and the incidence of panic attacks in the relatives should be independent of panic attacks in the proband. We interviewed 50 probands with mitral prolapse and obtained family history data on panic attacks in their first degree relatives. The incidence of panic attacks in these relatives was 4.5 +/- 1.4% which is consistent with control rates which we have reported in previous studies. Twelve MVP probands also had panic attacks. The incidence of panic attacks in their relatives (15.7 +/- 5.1%) was significantly higher than the rate found among relatives of 38 probands without panic attacks (1.2 +/- 0.8%). These findings are consistent with the hypothesis that mitral prolapse and panic attacks are segregating independently in these families.
journal_name
J Affect Disordjournal_title
Journal of affective disordersauthors
Crowe RR,Gaffney G,Kerber Rdoi
10.1016/0165-0327(82)90042-8subject
Has Abstractpub_date
1982-06-01 00:00:00pages
121-5issue
2eissn
0165-0327issn
1573-2517pii
0165-0327(82)90042-8journal_volume
4pub_type
杂志文章abstract：BACKGROUND:Comorbidity between Substance Use Disorders (SUDs) and major depression is highly prevalent. This systematic review and meta-analysis aimed to estimate the prevalence of SUDs in subjects diagnosed with a major depressive disorder (MDD) in community, inpatient and outpatient settings. METHODS:A comprehensive...
journal_title：Journal of affective disorders
pub_type： 杂志文章,评审
doi：10.1016/j.jad.2020.01.141
更新日期：2020-04-01 00:00:00
abstract：BACKGROUND:This study examined whether intranasal oxytocin enhances the stress-buffering effects of social support during experimentally induced pain, taking into account the role of individual differences in attachment security. METHODS:Female participants (N = 193) were randomly assigned to oxytocin (24 IU intranasa...
journal_title：Journal of affective disorders
pub_type： 杂志文章
doi：10.1016/j.jad.2020.09.057
更新日期：2021-01-01 00:00:00
abstract：BACKGROUND:Magnetic resonance imaging (MRI) studies have yielded inconsistent findings with regard to subcortical volumetric abnormalities in patients with bipolar I disorder. Duration of illness and long term medication intake could have confounded the findings. METHOD:Volumes of nine subcortical structures were comp...
journal_title：Journal of affective disorders
pub_type： 杂志文章
doi：10.1016/j.jad.2017.06.051
更新日期：2017-11-01 00:00:00
abstract：BACKGROUND:Depressed mood, anhedonia, psychomotor retardation and alterations of circadian rhythm are core features of the depressive syndrome. Its neural correlates can be located within a frontal-striatal-tegmental neural network, commonly referred to as the reward circuit. It is the aim of this article to review lit...
journal_title：Journal of affective disorders
pub_type： 杂志文章,评审
doi：10.1016/j.jad.2015.06.041
更新日期：2015-11-15 00:00:00
abstract：BACKGROUND:Emotional dysregulation in subjects with attention deficit and hyperactivity disorder (ADHD) is a topic of growing interest among clinicians and researchers. The present study aims at investigating components of emotional dysregulation in adults ADHD compared to subjects suffering from bipolar disorder (BD)....
journal_title：Journal of affective disorders
pub_type： 杂志文章,评审
doi：10.1016/j.jad.2016.03.047
更新日期：2016-07-01 00:00:00
abstract：BACKGROUND:Previous studies have shown an association between prepregnancy BMI and postpartum depression, but little is known about this association beyond one year postpartum and the influence of postpartum weight retention (PPWR). METHODS:We used data from 70355 mothers from the Danish National Birth Cohort to estim...
journal_title：Journal of affective disorders
pub_type： 杂志文章
doi：10.1016/j.jad.2015.04.053
更新日期：2015-09-01 00:00:00
abstract：BACKGROUND:The purpose of the present study was to examine the degree to which trait and cognitive (looming cognitive style) measures of anxiety are associated with suicidal ideation (SI), as well as whether trait and cognitive (time misperception) measures of impulsivity moderate the association between these variable...
journal_title：Journal of affective disorders
pub_type： 杂志文章
doi：10.1016/j.jad.2012.05.034
更新日期：2012-12-20 00:00:00
abstract：BACKGROUND:There are several lines of evidence implicating a glial abnormality in the pathophysiology of bipolar disorder. Previous studies have reported a wide range of abnormalities but with little consistency between their findings. METHODS:Sixty frozen postmortem temporal cortical brain samples from normal, schizo...
journal_title：Journal of affective disorders
pub_type： 杂志文章
doi：10.1016/j.jad.2005.08.015
更新日期：2006-03-01 00:00:00
abstract：BACKGROUND:Anxiety and depression are common during pregnancy and associated with adverse outcomes for the mother and infant if left untreated. Despite the need to improve treatment accessibility and uptake in this population, no studies have investigated internet-delivered cognitive behavioural therapy (iCBT) for ante...
journal_title：Journal of affective disorders
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.jad.2018.09.057
更新日期：2019-01-15 00:00:00
abstract：BACKGROUND:Recent research indicates that different couple and family interventions are effective in the treatment of depressed patients. However, how these psychosocial interventions work, has been less well investigated. In order to better understand the underlying treatment processes, helpful treatment experiences o...
journal_title：Journal of affective disorders
pub_type： 杂志文章
doi：10.1016/j.jad.2011.05.050
更新日期：2011-11-01 00:00:00
abstract：BACKGROUND:Results of single photon emission computed tomography (SPECT) regarding mood disorders have been inconsistent. The aim of the study was to elucidate factors contributing to changes in cerebral blood flow in patients with major depressive disorder. METHODS:A total of 89 consecutive patients diagnosed with ma...
journal_title：Journal of affective disorders
pub_type： 杂志文章
doi：10.1016/j.jad.2005.03.004
更新日期：2005-07-01 00:00:00
abstract：BACKGROUND:The Harvard Trauma Questionnaire (HTQ) is the predominant questionnaire for assessing PTSD in trauma-affected refugees. Although the scale is increasingly used for measuring treatment outcomes, it has never been specifically validated for such use. The current study does so by testing the HTQ with the Rasch ...
journal_title：Journal of affective disorders
pub_type： 杂志文章
doi：10.1016/j.jad.2020.08.071
更新日期：2020-12-01 00:00:00
abstract：:Thirteen patients with major depressive disorder, 25 patients with dysthymia and 12 healthy controls underwent ergopsychometric testing. The effect of self-paced and set-paced load on mood, vigilance and perseveration tendency was recorded. Within the clinical groups, various types of load seemed to result mainly in v...
journal_title：Journal of affective disorders
pub_type： 杂志文章
doi：10.1016/0165-0327(91)90095-a
更新日期：1991-10-01 00:00:00
abstract：BACKGROUND:The daily pattern of motor activity and the autonomic cardiovascular regulation were studied in major depression to quantify changes in psychomotor function and autonomic cardiac functioning. Additionally, relationships between motor activity parameters, cardiovascular measures and specific clinical features...
journal_title：Journal of affective disorders
pub_type： 杂志文章
doi：10.1016/s0165-0327(02)00066-6
更新日期：2003-09-01 00:00:00
abstract：BACKGROUND:Postnatal depression can have a major impact on the lives of women affected and on those around them. While effective treatments are available, it would be preferable to prevent the condition. The aim of this review was to examine the effectiveness of antenatal interventions designed to prevent postnatal dep...
journal_title：Journal of affective disorders
pub_type： 杂志文章,评审
doi：10.1016/j.jad.2011.02.029
更新日期：2012-03-01 00:00:00
abstract：BACKGROUND:Bipolar disorder (BD) is associated with inhibitory deficits characterized by a reduced ability to control inappropriate actions or thoughts. While aspects of inhibition such as exaggerated novelty-seeking and perseveration are quantified in rodent exploration of novel environments, similar models are rarely...
journal_title：Journal of affective disorders
pub_type： 杂志文章
doi：10.1016/j.jad.2013.05.020
更新日期：2013-09-25 00:00:00
abstract：OBJECTIVE:Histories of childhood trauma (CT) are risk factors for affect dysregulation and poor clinical outcomes in women with bipolar disorder (BD). While much is known about the link between BD and CT in adult patients, there is limited data on this research topic in pediatric BD (PBD). The present study aims to inv...
journal_title：Journal of affective disorders
pub_type： 杂志文章
doi：10.1016/j.jad.2018.12.007
更新日期：2019-03-15 00:00:00
abstract：BACKGROUND:Antidepressant treatment is associated with a high rate of poor response, and thus, biomarker development is warranted. METHODS:We aimed to synthesize studies investigating gene expression, small RNAs, and epigenomic biomarkers of antidepressant response. We conducted a narrative review of the literature. ...
journal_title：Journal of affective disorders
pub_type： 杂志文章,评审
doi：10.1016/j.jad.2017.08.087
更新日期：2018-06-01 00:00:00
abstract：BACKGROUND:Repetitive transcranial magnetic stimulation (rTMS) is an effective adjuvant treatment for depression. Many patients with depression have comorbid anxiety symptoms. However, previous rTMS studies have focused on patients with depression, and often excluded comorbid anxiety. This real-world study aimed to inv...
journal_title：Journal of affective disorders
pub_type： 杂志文章
doi：10.1016/j.jad.2020.05.151
更新日期：2020-11-01 00:00:00
abstract：BACKGROUND:While depression during pregnancy is one of the strongest risk factors for postnatal depression, it has been comparatively little studied, particularly in sub-Saharan Africa. METHODS:Cohort study nested within 4-weekly surveillance of all women of reproductive age to identify pregnancies and collect data on...
journal_title：Journal of affective disorders
pub_type： 杂志文章
doi：10.1016/j.jad.2014.04.009
更新日期：2014-08-01 00:00:00
abstract：BACKGROUND:While major depressive disorder (MDD) is considered to be a heterogeneous disorder, the nature of the heterogeneity remains unclear. Studies have attempted to classify patients with MDD using latent variable techniques, yet the empirical approaches to symptom-based subtyping of MDD have not provided conclusi...
journal_title：Journal of affective disorders
pub_type： 杂志文章
doi：10.1016/j.jad.2017.03.053
更新日期：2017-08-01 00:00:00
abstract：BACKGROUND:Evidence suggests that patients with bipolar disorder have an elevated risk for comorbid posttraumatic stress disorder (PTSD) compared to those without a bipolar diagnosis. Although bipolar disorder is associated with decreased health-related quality of life (HRQOL), it is unclear whether comorbid PTSD inter...
journal_title：Journal of affective disorders
pub_type： 杂志文章,多中心研究,评审
doi：10.1016/j.jad.2012.08.005
更新日期：2013-02-20 00:00:00
abstract：BACKGROUND:Depression is the single largest contributor to non-fatal health loss worldwide. A role of inflammation in major depressive disorder (MDD) was suggested, and we sought to determine if cytokine levels predict the severity of depressive symptomatology or distinguish MDD patients from healthy controls (HCs). M...
journal_title：Journal of affective disorders
pub_type： 杂志文章
doi：10.1016/j.jad.2019.02.042
更新日期：2019-04-15 00:00:00
abstract：:There are an increasing number of pharmacologic therapies for bipolar disorder. Two of these agents, the anticonvulsants carbamazepine (CBZ) and valproate (VPA), were first developed over 30 years ago for the treatment of epilepsy, and subsequent studies demonstrated that they are also effective in the treatment of ac...
journal_title：Journal of affective disorders
pub_type： 杂志文章,评审
doi：10.1016/j.jad.2006.04.030
更新日期：2006-10-01 00:00:00
abstract：OBJECTIVES:Little is known about how patients successfully manage their bipolar disorder (BD). This is a remarkable gap in the BD literature, given that current treatments are inadequate and information about beneficial self-management strategies could have clinical and theoretical implications. Here, we present result...
journal_title：Journal of affective disorders
pub_type： 杂志文章
doi：10.1016/j.jad.2009.11.004
更新日期：2010-07-01 00:00:00
abstract：BACKGROUND:Alcohol misuse and depression represent two major social and health problems globally. These conditions commonly co-occur and both are associated with significant cognitive impairment. Despite this, few studies have examined the impact on cognitive functioning of co-occurring alcohol misuse and depression. T...
journal_title：Journal of affective disorders
pub_type： 杂志文章,评审
doi：10.1016/j.jad.2015.03.024
更新日期：2015-07-01 00:00:00
abstract：BACKGROUND:A history of self-harm is a major risk factor for suicide. Some patients are more likely than others to repeat suicidal behaviour after an episode of self-harm. Insight in the relation between current thoughts of self-harm, motives for the self-harm episode and perceived problems may improve prevention strat...
journal_title：Journal of affective disorders
pub_type： 杂志文章
doi：10.1016/j.jad.2018.07.047
更新日期：2018-11-01 00:00:00
abstract：:Differencing and cross-correlations are useful and straightforward methods for dealing with relationships between variables measured over short periods of time. Without such transformations of time-series data, spurious relationships may emerge and the true nature of underlying relationships may be obscured. This rean...
journal_title：Journal of affective disorders
pub_type： 杂志文章
doi：10.1016/0165-0327(90)90056-e
更新日期：1990-12-01 00:00:00
abstract：BACKGROUND:Depression in pregnancy is a serious health issue; however, anxiety in pregnancy, with a reported higher prevalence, may also be a serious issue. Anxiety symptoms in pregnancy can relate to several anxiety types, such as general anxiety, anxiety disorders, and pregnancy-related anxiety (PrA), anxiety charact...
journal_title：Journal of affective disorders
pub_type： 杂志文章,评审
doi：10.1016/j.jad.2015.01.039
更新日期：2015-05-01 00:00:00
abstract：:The 'default mode network' (DMN), a collection of brain regions including the posterior cingulate cortex (PCC), shows reliable inter-regional functional connectivity at rest. It has been implicated in rumination and other negative affective states, but its role in suicidal ideation is not well understood. We employed ...
journal_title：Journal of affective disorders
pub_type： 杂志文章
doi：10.1016/j.jad.2017.01.013
更新日期：2017-04-01 00:00:00
