当前位置： SCI文献检索 > JOURNAL OF AFFECTIVE DISORDERS期刊下所有文献 > Alterations of functional connectivity and intrinsic activity within the cingulate cortex of suicidal ideators.

Alterations of functional connectivity and intrinsic activity within the cingulate cortex of suicidal ideators.

Abstract：

:The 'default mode network' (DMN), a collection of brain regions including the posterior cingulate cortex (PCC), shows reliable inter-regional functional connectivity at rest. It has been implicated in rumination and other negative affective states, but its role in suicidal ideation is not well understood. We employed seed based functional connectivity methods to analyze resting state fMRI data in 34 suicidal ideators and 40 healthy control participants. Whole-brain connectivity with dorsal PCC or ventral PCC was broadly intact between the two groups, but while the control participants showed greater coupling between the dorsal anterior cingulate cortex (dACC) and dorsal PCC, compared to the dACC and ventral PCC, this difference was reversed in the ideators. Furthermore, ongoing low frequency BOLD signal in these three regions (dorsal, ventral PCC, dACC) was reduced in the ideators. The structural integrity of the cingulum bundle, as measured using diffusion tensor imaging (DTI), also explained variation in the functional connectivity measures but did not abolish the group differences. Together, these findings provide evidence of abnormalities in the DMN underlying the tendency towards suicidal ideation.

journal_name

J Affect Disord

journal_title

Journal of affective disorders

authors

Chase HW,Segreti AM,Keller TA,Cherkassky VL,Just MA,Pan LA,Brent DA

doi

10.1016/j.jad.2017.01.013

subject

Has Abstract

pub_date

2017-04-01 00:00:00

pages

78-85

eissn

0165-0327

issn

1573-2517

pii

S0165-0327(16)31803-1

journal_volume

212

pub_type

杂志文章

相关文献

JOURNAL OF AFFECTIVE DISORDERS文献大全
  • Alexithymia in healthy women: a brain morphology study.

    abstract：BACKGROUND:Alexithymia relates to difficulty recognizing and describing own feelings. Recent literature shows that specific structures process emotions. Aim of this study was to investigate whether alexithymia is associated with a specific cerebral morphology of candidate structures in healthy adults. METHODS:Fifty-fo...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/j.jad.2008.07.013

    authors： Borsci G,Boccardi M,Rossi R,Rossi G,Perez J,Bonetti M,Frisoni GB

    更新日期：2009-04-01 00:00:00

  • Acute and long-term treatment outcome in depressed inpatients with vs. without anxious features: results of a one-year follow-up study.

    abstract：BACKGROUND:Anxious depression (AD) is common in patients with unipolar depression. It remains unclear if they have a higher level of depressive symptoms, a higher risk of non-response, a poorer prognosis and a higher relapse rate compared to non-anxious depressed (non-AD) patients. METHODS:168 patients took part in al...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/j.jad.2013.05.043

    authors： Köhler S,Unger T,Hoffmann S,Steinacher B,Fydrich T

    更新日期：2013-09-25 00:00:00

  • Inhibitory deficits in euthymic bipolar disorder patients assessed in the human behavioral pattern monitor.

    abstract：BACKGROUND:Bipolar disorder (BD) is associated with inhibitory deficits characterized by a reduced ability to control inappropriate actions or thoughts. While aspects of inhibition such as exaggerated novelty-seeking and perseveration are quantified in rodent exploration of novel environments, similar models are rarely...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/j.jad.2013.05.020

    authors： Henry BL,Minassian A,Patt VM,Hua J,Young JW,Geyer MA,Perry W

    更新日期：2013-09-25 00:00:00

  • Increased plasma peroxides and serum oxidized low density lipoprotein antibodies in major depression: markers that further explain the higher incidence of neurodegeneration and coronary artery disease.

    abstract：BACKGROUND:Major depression is characterized by a decreased antioxidant status, an induction of the inflammatory and oxidative and nitrosative (IO&NS) pathways and inflammatory-neurodegenerative (I&ND) pathways. This study examines two markers of oxidative stress in depression, i.e. plasma peroxides and serum oxidized ...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/j.jad.2009.12.014

    authors： Maes M,Mihaylova I,Kubera M,Uytterhoeven M,Vrydags N,Bosmans E

    更新日期：2010-09-01 00:00:00

  • Childhood trauma associates with clinical features of bipolar disorder in a sample of Chinese patients.

    abstract：OBJECTIVES:Childhood trauma is a major public health problem which has a long-term consequence, a few studies have examined the relationship between childhood trauma and clinical features of bipolar disorder, most in western culture, with no such studies done in Chinese culture. METHODS:The CTQ-SF was administered to ...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/j.jad.2014.06.017

    authors： Li XB,Liu JT,Zhu XZ,Zhang L,Tang YL,Wang CY

    更新日期：2014-10-01 00:00:00

  • Weight gain, obesity, and metabolic indices following a first manic episode: prospective 12-month data from the Systematic Treatment Optimization Program for Early Mania (STOP-EM).

    abstract：BACKGROUND:Numerous studies have demonstrated an association between bipolar disorder (BD) and obesity. However, these reports are limited by retrospective or cross-sectional designs, and the assessment of patients with lengthy illnesses. Prospective data, and data on weight gain early in the course of BD, are lacking....

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/j.jad.2009.10.023

    authors： Bond DJ,Kauer-Sant'Anna M,Lam RW,Yatham LN

    更新日期：2010-07-01 00:00:00

  • A systematic review of measures for psychological well-being in physical activity studies and identification of critical issues.

    abstract：BACKGROUND:The health benefits of physical activity (PA) have been well documented in the literature. The relationship between PA and psychological well-being (PWB) has received increasing attention. AIM:This study aimed to systematically review the measurement of PWB in PA studies and examine the major findings of th...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/j.jad.2019.06.024

    authors： Zhang Z,Chen W

    更新日期：2019-09-01 00:00:00

  • Prevalence of self-reported seasonal affective disorders and the validity of the seasonal pattern assessment questionnaire in young adults Findings from a Swiss community study.

    abstract：BACKGROUND:The objective of this study was to expand the knowledge on the prevalence of self-reported Seasonal Affective Disorder (SAD) and to further study the validity of the Seasonal Pattern Assessment Questionnaire (SPAQ). METHODS:A total of N=844 young adults were assessed in a Swiss community study by use of the...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章,多中心研究

    doi：10.1016/j.jad.2008.09.016

    authors： Steinhausen HC,Gundelfinger R,Winkler Metzke C

    更新日期：2009-06-01 00:00:00

  • Depression management interests among Alaska Native and American Indian adults in primary care.

    abstract：BACKGROUND:Depression remains the second leading cause of disability worldwide. Symptoms of depression are expressed and experienced differently across cultural groups, impacting treatment decisions. Patient preferences predict service utilization, treatment selection and persistence, as well as health outcomes for med...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/j.jad.2018.05.075

    authors： Avey JP,Dirks LG,Dillard DA,Manson SM,Merrick M,Smith JJ,Prickette GC,Tetpon S,Galbreath D,Triplett B,Robinson RF

    更新日期：2018-10-15 00:00:00

  • Validation of screening tools for antenatal depression in Malawi--a comparison of the Edinburgh Postnatal Depression Scale and Self Reporting Questionnaire.

    abstract：BACKGROUND:The detection of antenatal depression in resource-limited settings such as Malawi, Africa, is important and requires an accurate and practical screening tool. It is not known which questionnaire would be most suitable for this purpose. METHOD:A rigorously translated and modified Chichewa version of the Edin...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/j.jad.2013.05.036

    authors： Stewart RC,Umar E,Tomenson B,Creed F

    更新日期：2013-09-25 00:00:00

  • Clinical pilot study of transcranial direct current stimulation combined with Cognitive Emotional Training for medication resistant depression.

    abstract：BACKGROUND:While the clinical results from transcranial direct current stimulation (tDCS) for the treatment of depression have been promising, antidepressant effects in patients with medication resistance have been suboptimal. There is therefore a need to further optimise tDCS for medication resistant patients. In this...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/j.jad.2018.02.021

    authors： Martin DM,Teng JZ,Lo TY,Alonzo A,Goh T,Iacoviello BM,Hoch MM,Loo CK

    更新日期：2018-05-01 00:00:00

  • Depression with and without a history of psychotic symptoms in the general population: sociodemographic and clinical characteristics.

    abstract：BACKGROUND:The aim of this study was to find the sociodemographic and clinical characteristics of major depressive episode (MDE) with (MDE-HPS+) and without a history of psychotic symptoms (MDE-HPS) in the general population. METHODS:The Mental Health in the General Population survey interviewed 38,694 individuals in ...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/j.jad.2020.04.048

    authors： Benard V,Pignon B,Geoffroy PA,Benradia I,Roelandt JL,Rolland B,Fovet T,D'Hondt F,Thomas P,Vaiva G,Amad A

    更新日期：2020-08-01 00:00:00

  • Decreased lymphocyte beta-adrenoreceptor function correlates with less agoraphobia and better outcome in panic disorder.

    abstract：:Previous studies have demonstrated reduced function of peripheral beta-adrenoreceptors in panic disorder with agoraphobia (PDA). We recently reported that decreased lymphocyte beta-receptor function was associated with milder agoraphobia and better treatment response in PDA. We now report on lymphocyte beta-receptor f...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/0165-0327(93)90115-z

    authors： Maddock RJ,Gietzen DW,Goodman TA

    更新日期：1993-09-01 00:00:00

  • Impaired mitogen-induced lymphocyte responses and the hypothalamic-pituitary-adrenal axis in depressive disorders.

    abstract：:The lymphocyte stimulation responses to the mitogens phytohemagglutinin (PHA), concanavalin A (Con A) and pokeweed (PWM) were investigated in 30 hospitalized depressed women undergoing a dexamethasone suppression test (DST). Patients were classified according to DSM-III as having major depression with melancholia, wit...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/0165-0327(89)90054-2

    authors： Cosyns P,Maes M,Vandewoude M,Stevens WJ,De Clerck LS,Schotte C

    更新日期：1989-01-01 00:00:00

  • Schneiderian first rank symptoms predict poor outcome within first episode manic psychosis.

    abstract：BACKGROUND:The validity of a sub-classification of affective psychosis according to the mood congruence of psychotic features has been questioned in the literature. While some authors have found a correlation between such symptoms and outcome, their predictive value was rather limited in these studies. METHOD:Prospect...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/j.jad.2003.09.003

    authors： Conus P,Abdel-Baki A,Harrigan S,Lambert M,McGorry PD

    更新日期：2004-09-01 00:00:00

  • Inflammation and remission in older patients with depression treated with electroconvulsive therapy; findings from the MODECT study✰.

    abstract：BACKGROUND:Compelling evidence links elevated levels of C-reactive protein (CRP) and other inflammatory markers to poor treatment outcome of antidepressant medication. Little is known about the contribution of low-grade inflammation to treatment response to electroconvulsive therapy (ECT) in severely depressed patients...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/j.jad.2019.06.040

    authors： Carlier A,Berkhof JG,Rozing M,Bouckaert F,Sienaert P,Eikelenboom P,Veerhuis R,Vandenbulcke M,Berkhof J,Stek ML,Rhebergen D,Dols A,Exel EV

    更新日期：2019-09-01 00:00:00

  • Hypofunction of left dorsolateral prefrontal cortex in depression during verbal fluency task: A multi-channel near-infrared spectroscopy study.

    abstract：BACKGROUND:Previous functional neuroimaging studies of depression have demonstrated frontotemporal dysfunction, including the dorsolateral prefrontal cortex, while patients perform working memory and language comprehension tasks. Recent near-infrared spectroscopy (NIRS) studies have shown frontotemporal hypofunction in...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/j.jad.2018.01.010

    authors： Akiyama T,Koeda M,Okubo Y,Kimura M

    更新日期：2018-04-15 00:00:00

  • Psychological impact of healthcare workers in China during COVID-19 pneumonia epidemic: A multi-center cross-sectional survey investigation.

    abstract：BACKGROUND:Since the outbreak of 2019 new coronavirus (COVID-19) pneumonia, healthcare workers (HCW) have suffered psychological stress. The present study is to examine the prevalence of stress, anxiety and depression of HCW in China during the COVID-19 epidemic, and to determine the risk factors predicting psychologic...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章,多中心研究

    doi：10.1016/j.jad.2020.05.081

    authors： Xiao X,Zhu X,Fu S,Hu Y,Li X,Xiao J

    更新日期：2020-09-01 00:00:00

  • Insomnia and hypersomnia in major depressive episode: Prevalence, sociodemographic characteristics and psychiatric comorbidity in a population-based study.

    abstract：OBJECTIVES:To examine (i) the frequency of different sleep complaints (early wake-up, trouble falling asleep, hypersomnia) and their co-occurrence and (ii) the sociodemographic characteristics and psychiatric comorbidity associated with each type of sleep profiles. METHODS:Data were drawn from the Wave 2 National Epid...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/j.jad.2017.09.032

    authors： Geoffroy PA,Hoertel N,Etain B,Bellivier F,Delorme R,Limosin F,Peyre H

    更新日期：2018-01-15 00:00:00

  • The prognosis of undetected depression in older general practice patients. A one year follow-up study.

    abstract：BACKGROUND:Late-life depression often remains undetected in primary care. However, as there is evidence that GPs do identify those with the most severe and persistent disorders, it is important to know more about the prognosis of depressive disorders that are not detected by GPs. METHODS:A one-year follow-up study of ...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/j.jad.2008.06.006

    authors： Licht-Strunk E,Beekman AT,de Haan M,van Marwijk HW

    更新日期：2009-04-01 00:00:00

  • Vitamin D and depression.

    abstract：OBJECTIVE:To examine whether vitamin D deficiency or insufficiency is associated with depression and whether vitamin D supplementation is an effective treatment for depression. METHOD:Empirical papers published in recent years were identified using three search engines and online databases - PubMed, Google Scholar and...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章,评审

    doi：10.1016/j.jad.2016.08.082

    authors： Parker GB,Brotchie H,Graham RK

    更新日期：2017-01-15 00:00:00

  • The effect of dexamethasone dosage upon plasma cortisol and dexamethasone during the DST.

    abstract：:To investigate the effect of dexamethasone dosage upon the outcome of the dexamethasone suppression test (DST) and the role of concurrent plasma dexamethasone concentrations, four different dexamethasone dosages were administered to 119 hospitalized depressed patients (0.5 mg: n = 12; 1.0 mg: n = 30; 1.5 mg: n = 42; 2...

    journal_title：Journal of affective disorders

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1016/0165-0327(90)90018-4

    authors： Wiedemann K,Holsboer F

    更新日期：1990-06-01 00:00:00

  • Peritraumatic tonic immobility predicts a poor response to pharmacological treatment in victims of urban violence with PTSD.

    abstract：INTRODUCTION:Tonic immobility is the last defense against predation in animals and is characterized by paralysis and analgesia. In humans, it has only been reported in women victims of sexual abuse. OBJECTIVE:This study evaluated the prevalence of peritraumatic tonic immobility (PTI) in patients with PTSD and investig...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/j.jad.2007.07.015

    authors： Fiszman A,Mendlowicz MV,Marques-Portella C,Volchan E,Coutinho ES,Souza WF,Rocha V,Lima AA,Salomão FP,Mari JJ,Figueira I

    更新日期：2008-04-01 00:00:00

  • Carbon dioxide induces erratic respiratory responses in bipolar disorder.

    abstract：BACKGROUND:CO(2) respiration stimulates both anxiety and dyspnea ("air hunger") and has long been used to study panic vulnerability and respiratory control. High comorbidity with panic attacks suggests individuals with bipolar disorder may also mount a heightened anxiety response to CO(2). Moreover, problems in the aro...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/j.jad.2008.03.020

    authors： Mackinnon DF,Craighead B,Lorenz L

    更新日期：2009-01-01 00:00:00

  • Gender differences in the prevalence of depression: a survey in primary care.

    abstract：:Epidemiological surveys demonstrate that unipolar depression is more common in females than in males. Gender-specific cultural and social factors may contribute to the female preponderance. This study explores this possibility in a cross-cultural sample of general-practice patients systematically recruited in the WHO ...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/s0165-0327(98)00131-1

    authors： Maier W,Gänsicke M,Gater R,Rezaki M,Tiemens B,Urzúa RF

    更新日期：1999-06-01 00:00:00

  • Determinants of (non-)recognition of depression by general practitioners: results of the Netherlands Study of Depression and Anxiety.

    abstract：BACKGROUND:Although most depressed patients are treated in primary care, not all are recognized as such. This study explores the determinants of (non-)recognition of depression by general practitioners (GPs), with a focus on specific depression symptoms as possible determinants. METHODS:Recognition of depression by GP...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/j.jad.2012.01.006

    authors： Piek E,Nolen WA,van der Meer K,Joling KJ,Kollen BJ,Penninx BW,van Marwijk HW,van Hout HP

    更新日期：2012-05-01 00:00:00

  • Societal burden of adolescent depression, an overview and cost-of-illness study.

    abstract：BACKGROUND:Depression in adolescents is a serious problem to society because of the high prevalence rate, the high subjective burden of illness and negative (economic) consequences. Information regarding the economic burden of adolescent depression is scarce. The goal of this study is twofold. First, an overview of the...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章,评审

    doi：10.1016/j.jad.2018.06.015

    authors： Bodden DHM,Stikkelbroek Y,Dirksen CD

    更新日期：2018-12-01 00:00:00

  • Pregnancy anxiety: A systematic review of current scales.

    abstract：BACKGROUND:Depression in pregnancy is a serious health issue; however, anxiety in pregnancy, with a reported higher prevalence, may also be a serious issue. Anxiety symptoms in pregnancy can relate to several anxiety types, such as general anxiety, anxiety disorders, and pregnancy-related anxiety (PrA), anxiety charact...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章,评审

    doi：10.1016/j.jad.2015.01.039

    authors： Brunton RJ,Dryer R,Saliba A,Kohlhoff J

    更新日期：2015-05-01 00:00:00

  • Atypical cognitive profile in patients with depression after myocardial infarction.

    abstract：BACKGROUND:We evaluated the cognitive profile of 48 patients with major depression following their first myocardial infarction (MI). METHODS:The cognitive performance of the patients was compared with the performance of 48 non-depressed MI patients and 48 healthy controls. RESULTS:Depressed MI patients performed slow...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/s0165-0327(01)00348-2

    authors： Dijkstra JB,Strik JJ,Lousberg R,Prickaerts J,Riedel WJ,Jolles J,van Praag HM,Honig A

    更新日期：2002-07-01 00:00:00

  • Functional disability, depression, and suicidal ideation in older prisoners.

    abstract：BACKGROUND:The population of older prisoners (age ≥50), a group with high suicide rates, is growing. We sought to explore the associations among functional disability, depression, and suicidal ideation (SI) among older prisoners, focusing on the mediating role of depression. METHODS:Study participants were 220 sentenc...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/j.jad.2020.01.156

    authors： Barry LC,Coman E,Wakefield D,Trestman RL,Conwell Y,Steffens DC

    更新日期：2020-04-01 00:00:00