Abstract:
BACKGROUND:Depression is considered the second leading cause of disability worldwide. AIM:To describe the clinical characteristics and the evolution of major depressive disorder (MDD) in secondary care. To evaluate the association between socio-demographic and clinic variables with the first or recurrent major depressive events (MDE). MATERIAL AND METHODS:Clinical features, treatment, remission and duration of MDE were evaluated during a follow up lasting 12 months in 112 participants aged 44 ± 15 years (79% women). Patients were assessed as outpatients every three months at three psychiatric care centers of Chile. Clinical interviews were carried out using DSM-IV diagnostic criteria checklists and the Hamilton Depression Scale was applied. RESULTS:Most patients were referred from primary care. The mean time lapse for referral to the secondary level was 10.8 months. Most patients had episodes that were recurrent, severe, with a high rate of psychosis, with suicide attempts and melancholic features and with psychiatric and medical comorbidities. Remission rate was 27.5%. In only 16 % of patients, the episode lasted six months or less. The group with recurrent episodes had different age, sex and clinical features. CONCLUSIONS:MDD treated at the secondary care level is severe and its symptoms are intense. The time lapse prior to referral was prolonged. Primary care management and referral of these patients should be studied more closely.
journal_name
Rev Med Chiljournal_title
Revista medica de Chileauthors
Salvo L,Saldivia S,Parra C,Rodríguez R,Cifuentes M,Acevedo P,Díaz M,Ormazabal M,Guerra I,Navarrete N,Bravo V,Castro Adoi
10.4067/S0034-98872017000300007subject
Has Abstractpub_date
2017-03-01 00:00:00pages
335-343issue
3eissn
0034-9887issn
0717-6163pii
S0034-98872017000300007journal_volume
145pub_type
杂志文章abstract:BACKGROUND:An atypical cervical smear may represent a wide variety of lesions, from banal diseases to invasive neoplastic lesions. AIM:To study the evolution of atypical cervical smears in a highly controlled women population. MATERIAL AND METHODS:A retrospective analysis of 117 women with atypical cervical smears, d...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1998-03-01 00:00:00
abstract:BACKGROUND:Paracetamol (acetaminophen) is an analgesic and antipyretic drug widely used across the world. Its ingestion is one of the most common causes of drug overdose. In the United States is the first cause of acute hepatitis in adults. AIM:To describe the epidemiological profile of paracetamol overdose in Chile. ...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:10.4067/S0034-98872012000300005
更新日期:2012-03-01 00:00:00
abstract::The association of hyperthyroxinemia and euthyroidism is frequent and characterized by high plasma thyroxin concentrations, normal TSH values and absence of clinical signs of hyperthyroidism. We report an asymptomatic 28 years old male presenting with a serum total plasma thyroxin of 18.5 micrograms/dl (N 6.1-12.5), a...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1999-02-01 00:00:00
abstract:BACKGROUND:Community-acquired pneumonia in adults is a serious health problem in the ambulatory care setting. AIM:To define clinical variables associated with the presence of pneumonia in adult patients presenting with fever or respiratory symptoms to the emergency department. MATERIAL AND METHODS:Prospective study c...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:10.4067/s0034-98872007000200001
更新日期:2007-02-01 00:00:00
abstract:BACKGROUND:Chronic obstructive pulmonary disease (COPD) has a relevant impact on health-related quality of life (HRQoL). Short Form 6 dimensions (SF-6D) quality of life tool allows researchers to calculate preference-based utilities using data from SF-12 or SF-36 questionnaires. AIM:To provide normative values of SF-6...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:10.4067/S0034-98872017000200001
更新日期:2017-02-01 00:00:00
abstract::Adverse reactions to intravascular contrast media are infrequent in radiological practice and rarely pose a life threatening risk. Contraindication to contrast injection should be evaluated and prophylactic measures taken, if available, in patients with risk factors for adverse reactions. Details of pathogenesis, freq...
journal_title:Revista medica de Chile
pub_type: 杂志文章,评审
doi:
更新日期:1991-07-01 00:00:00
abstract::This article reviews some key issues of early rheumatoid arthritis such as the dfficulties to recognize this condition during the first months after onset. Therefore, three reference diagnostic criteria have been proposed for any patient presenting with more than three simultaneously inflammed joints, involvement of m...
journal_title:Revista medica de Chile
pub_type: 杂志文章,评审
doi:10.4067/s0034-98872008001100015
更新日期:2008-11-01 00:00:00
abstract::We report a 11 years old male diagnosed as a X-linked hyper-IgM syndrome that presented with recurrent infections and sclerosing cholangitis and later developed a gallbladder cancer. Immunological evaluation showed decreased levels of serum IgG and IgA with elevated levels of IgM. Study of CD40 ligand expression on mi...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:2003-03-01 00:00:00
abstract:BACKGROUND:Cellular immune mechanisms of the resistance to infection by T cruzi as well as the pathogenesis of Chagas disease are still controversial. AIM:To quantify and analyse the peripheral blood immune cells from chagasic and non chagasic patients by flow cytometry. PATIENTS AND METHODS:Peripheral blood samples ...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:2002-04-01 00:00:00
abstract:BACKGROUND:Since February 2002, Flextend electrode catheters are used at the Cardiovascular Unit of the Catholic University Clinical Hospital. These transvenous catheters have an IS-1 connector, silicone coating, active fixation and retractile helix with dexamethasone acetate. AIM:To report early and one year results ...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:/S0034-98872006000600011
更新日期:2006-06-01 00:00:00
abstract:BACKGROUND:The place of death has changed and coverage of medical attention at death varies according to the development level of countries. AIM:To assess the evolution of coverage of medical attention of the last disease and place of death as indicators of health care quality and development level, in the sixth regio...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:10.4067/s0034-98872007000800010
更新日期:2007-08-01 00:00:00
abstract::Recently, several groups have studied the influence of possible noxious elements present in the intrauterine environment which may favor the development of several diseases in the adult. There is evidence of an increased prevalence of some disorders in special risk groups of fetuses. In the small for gestational age p...
journal_title:Revista medica de Chile
pub_type: 杂志文章,评审
doi:
更新日期:2001-03-01 00:00:00
abstract::The effect of a prolonged course of oral acyclovir was evaluated in 55 pts with recurrent genital herpes (36 men and 19 women). The pts were voluntarily enrolled after an acute episode, with tissue culture viral isolation. All the pts received an initial course with 200 mg of acyclovir x 5 for 10 days. Then they were ...
journal_title:Revista medica de Chile
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1991-08-01 00:00:00
abstract::Medical specialization has brought about the need to guarantee suitability for its practice. The progressive changes in knowledge and the incorporation of specific technologies, set forth the need to periodically demonstrate this capacity. In developed countries different initiatives, that sooner or later will become ...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1993-12-01 00:00:00
abstract::An alternative strategy for cancer treatment is the manipulation of the immune system, denominated cancer immunotherapy. The immunotherapeutical use of cells of the immune system, like dendritic cells (DC), is being explored in different clinical protocols. Recently, we finalized a clinical phase I protocol, for the t...
journal_title:Revista medica de Chile
pub_type: 临床试验,杂志文章,评审
doi:
更新日期:2004-09-01 00:00:00
abstract::We evaluated the concentration of cefotaxime in the exudate from ischemic leg ulcers in 9 subjects with severe obstructive arterial disease. The administration of the drug was either systemic (1 g in 250 ml of saline given in 30 min) or regional at a vein of the foot while a tourniquet was applied at the level of the ...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1990-03-01 00:00:00
abstract::Glucocorticoids (cortisol in humans) are essential for numerous biological functions. Among critically ill patients, therapy with cortisol has gained strength in recent years, but clinical results have been mixed. A series of events, that may explain the diversity of clinical responses, occur from the synthesis of cor...
journal_title:Revista medica de Chile
pub_type: 杂志文章,评审
doi:10.4067/S0034-98872017000200011
更新日期:2017-02-01 00:00:00
abstract::In 160 girls from low and middle socio-economic class of Santiago we correlated the age at menarque with genetic markers such as ABO blood group, Rh, MN, Xg, haptoglobins, Esterase D and Phosphoglucomutase. No significant association of these markers and age at menarque was found. ...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1990-07-01 00:00:00
abstract:BACKGROUND:Rates of obesity reach high levels in Chile, with geographic, social and school variations. AIM:To identify factors at two levels associated with excessive weight in school children: child-family characteristics and school-neighborhood. MATERIAL AND METHODS:Using a cross-sectional and multi-step design, se...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:/S0034-98872007001200002
更新日期:2007-12-01 00:00:00
abstract:BACKGROUND:We report a 35-year-old female patient with a one year history of a pustular and painful erythematous dermatitis, located in great folds, pubis and abdomen. She was evaluated in primary health care, receiving antifungal treatment, antimicrobials, topical and systemic non-steroidal anti-inflammatory drugs, wi...
journal_title:Revista medica de Chile
pub_type: 杂志文章,评审
doi:10.4067/S0034-98872012000500012
更新日期:2012-05-01 00:00:00
abstract::Gestational Diabetes is characterized by different degrees of glucose intolerance that produce a series of fetal and perinatal alterations. During many years, in those cases of gestational diabetes that did not respond to nutritional interventions, the use of insulin was a proven treatment to achieve metabolic control...
journal_title:Revista medica de Chile
pub_type: 杂志文章,评审
doi:/S0034-98872008000700015
更新日期:2008-07-01 00:00:00
abstract::Mycoplasma infections have extrapulmonary manifestations that may be associated with respiratory symptoms and may have skin, heart, gastrointestinal, rheumatologic, neurologic, hematologic involvement. Cold agglutinin mediated autoimmune hemolytic anemia is the most common hematological manifestation. We report a 27-y...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:10.4067/S0034-98872014001000015
更新日期:2014-10-01 00:00:00
abstract::We evaluated the role of oxygen free radicals in the induction of acute stress gastric ulcer in rats. After 12 hr of immobility, ulcers of up to 4 mm were observed in the gastric mucosa. Pretreatment with allopurinol, a xanthine oxidase inhibitor, produced a significant reduction in the number and size of lesions (p <...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1990-09-01 00:00:00
abstract:BACKGROUND:Central nervous system damage associated to HTLV-I does not limit itself to the spinal cord, but also involves subcortical structures, producing cognitive impairment and behavioral changes which eventually could conform a new form of subcortical dementia. AIM:To study cognitive changes in patients with HTLV...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1999-04-01 00:00:00
abstract:BACKGROUND:In large series, nearly 60% of admissions for suspected acute coronary syndrome (ACS) had a non-coronary etiology of the pain. However, short term mortality of non recognized ACS patients, mistakenly discharged from the emergency room is at least twice greater than the expected if they would had been admitte...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:10.4067/s0034-98872007000700003
更新日期:2007-07-01 00:00:00
abstract:BACKGROUND:Systemic fungal infections and specifically invasive aspergillosis (IA) are associated with a high morbi-mortality rate in patients with hematologic malignancies. Itraconazole kinetic studies show that plasma levels are not satisfactory, even though there is a reduction of the severity in clinical cases. AI...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:/S0034-98872011000900003
更新日期:2011-09-01 00:00:00
abstract::Cerebral vasodilators (CVD) account for 1.6% of the annual expenditure on drugs in Chile. Two kinds are typified: what we have called orthodox CVD and calcium-channel blockers. They have two main uses in neurology: firstly, in acute ischaemic stroke where orthodox CVD (buflomedil, codergocrine mesylate, and nicergolin...
journal_title:Revista medica de Chile
pub_type: 杂志文章,评审
doi:
更新日期:1990-07-01 00:00:00
abstract:BACKGROUND:Cardiac rehabilitation (CR) programs play an important role in the control and prevention of new cardiac events. AIM:A survey was performed to evaluate the current situation of CR programs in Chile. MATERIAL AND METHODS:A questionnaire evaluating the structure of rehabilitation centers, characteristics of ...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:10.4067/S0034-98872012000500002
更新日期:2012-05-01 00:00:00
abstract::We studied genetic polymorphism of isoniazid acetylation in 47 tuberculous patients treated with 4 drugs between Aug 1987 and Dec 1988. Inactivation of isoniazid was estimated from urine samples after administration of the drug (10 mg/kg). There were 18 slow and 29 fast acetylators. The frequency of the slow mutant ge...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1989-12-01 00:00:00
abstract::Background Sleep duration may be a risk factor for cognitive impairment. Aim To investigate the association between sleep duration and cognitive function in Chilean older adults. Material and Methods We analyzed information from 1,384 participants aged > 60 years participating in the National Health Survey 2009-2010 w...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:10.4067/S0034-98872019001101398
更新日期:2019-11-01 00:00:00