Abstract:
:Glucocorticoids (cortisol in humans) are essential for numerous biological functions. Among critically ill patients, therapy with cortisol has gained strength in recent years, but clinical results have been mixed. A series of events, that may explain the diversity of clinical responses, occur from the synthesis of cortisol in the adrenal gland to the activation of the cortisol receptor by the hormone when it enters the nucleus of the target cell. Some of these events are revised; a proposition for identifying critically ill patients who may benefit with this therapy is suggested.
journal_name
Rev Med Chiljournal_title
Revista medica de Chileauthors
Guerrero Jdoi
10.4067/S0034-98872017000200011subject
Has Abstractpub_date
2017-02-01 00:00:00pages
230-239issue
2eissn
0034-9887issn
0717-6163pii
S0034-98872017000200011journal_volume
145pub_type
杂志文章,评审abstract::We report a 70-year-old woman, who had recently consumed shellfish, that was admitted to the intensive care unit with septic shock and died 19 hours later due to a multi-organic failure. Microbiological, serological and molecular assays confirmed a hemolytic tdh+ Vibrio cholerae non-01, non 0139 as the etiologic agent...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:/S0034-98872009000900008
更新日期:2009-09-01 00:00:00
abstract:BACKGROUND:There is close association between maltreatment during pregnancy and child abuse after birth. AIM:To compare anthropometric growth and use of health services of children whose mothers suffered maltreatment with children coming from families without domestic violence. SUBJECTS AND METHODS:A longitudinal stu...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:2003-12-01 00:00:00
abstract::Maturity-Onset Diabetes of the Young (MODY) refers to a heterogeneous group of monogenic diabetes. Unlike other types of MODY characterized by genetic defects in transcription factors, MODY 2 is triggered by metabolic alterations caused by mutations of glucokinase (GCK), the first enzyme of the glycolytic pathway. We ...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:10.4067/s0034-98872017000901203
更新日期:2017-09-01 00:00:00
abstract::Ultrasound is a sensible and specific method for the diagnosis, study of natural course and follow up of medical treatment of gallstones. Thus it is important to specify the concordance between echographic and pathological findings of the gallbladder. Ninety one patients were subjected to an ultrasound gallbladder exa...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1992-11-01 00:00:00
abstract::The five senses have had a fundamental importance for survival and socialization of human beings. From an evolutionary point of view the sense of smell is the oldest. This sense has a strong representation within the genome, allowing the existence of many types of receptors that allow us to capture multiple volatile o...
journal_title:Revista medica de Chile
pub_type: 杂志文章,评审
doi:/S0034-98872011000300013
更新日期:2011-03-01 00:00:00
abstract:BACKGROUND:The great variability in the clinical presentation of Chagas disease may depend in part in the genetic variability of Trypanosoma cruzi populations. AIM:To compare prepatent period, parasitemia, mortality and histological lesions in mice infected with two populations of Trypanosoma cruzi isolated in Chile. ...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:10.4067/s0034-98872005000400006
更新日期:2005-04-01 00:00:00
abstract::The practice of Medicine is exposed to everyday's ethical ventures that, even though not fundamental in a philosophical scope, are most crucial given its incidence and consequences to accessibility and equity in health care. A very special perception must emerge to allow us looking for those situations where moral con...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1994-01-01 00:00:00
abstract::Recently, several groups have studied the influence of possible noxious elements present in the intrauterine environment which may favor the development of several diseases in the adult. There is evidence of an increased prevalence of some disorders in special risk groups of fetuses. In the small for gestational age p...
journal_title:Revista medica de Chile
pub_type: 杂志文章,评审
doi:
更新日期:2001-03-01 00:00:00
abstract::The functional differentiation of mammary epithelial cells requires specific hormones, growth factors and chemical signals of the cellular environment. These signals consist in cell communication with the extracellular matrix and cell-cell interactions which through an intrincated mechanism lead to the events that tri...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1996-04-01 00:00:00
abstract::This article reports the results of 1080 ultrasonographic examinations of the liver in a clinic of the Ninth Region of Chile, using a SSD 620 Aloka equipment. In 61 examinations (5.6%) a focal liver lesion was found. Of these, 9 (14.7% of lesions) appeared as malignant (6 metastasis and 3 hepatomas) and 52 (85.3% of l...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1994-03-01 00:00:00
abstract:BACKGROUND:Osteoporotic hip fractures are devastating events in older women. There is a genetic modulation of bone phenotypic parameters including bone density (BMD) and bone fragility fractures. Vitamin D receptor (VDR) gene polymorphisms explain a small part of the genetic influence on BMD, whereas their effect on fr...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:/S0034-98872008000400008
更新日期:2008-04-01 00:00:00
abstract:BACKGROUND:Acute bacterial meningitis (ABM) is a serious disease that needs rapid diagnosis for an accurate treatment. The most important etiological agents are: Streptococcus pneumoniae, Neisseria meningitidis and Haemophilus influenzae type b. Overall pathogen detection rate in patients with ABM in Chile is 83%. AIM...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:/S0034-98872008000300009
更新日期:2008-03-01 00:00:00
abstract::Andrés Bello, a Venezuelan intellectual arrived in Chile in 1829. He had a decisive influence on the development of natural sciences and medical sciences in this country. The first formal teaching program in Medicine appeared in 1833, with few students due to the low social prestige of Medicine at that time. The Facul...
journal_title:Revista medica de Chile
pub_type: 传,历史文章,杂志文章
doi:
更新日期:1991-11-01 00:00:00
abstract::The aim of this work was to analyze the global incidence of congenital malformations at the Maternity of University of Chile Clinical Hospital in the periods between 1971 and 1977 and between 1982 and 1992. A significant and sustained increase in incidence was observed in the first period from 10.64 per 1000 born aliv...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1993-09-01 00:00:00
abstract::Arterial involvement in Behçet's disease (BD) is less common than venous lesions. The most commonly affected arteries are: the aorta, lower extremity arteries, mesenteric, femoral, coronary, renal, subclavian and pulmonary arteries. The rupture of pulmonary arteries is the main cause of death of patients with EB and t...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:10.4067/s0034-98872018000400528
更新日期:2018-04-01 00:00:00
abstract::A critical situation surrounds Internal Medicine and the training of internists. The crucial role of Internal Medicine as an integrating discipline in clinical medicine and its relationship with primary care medicine and the specialties is analyzed. The goals of a training program for general internists and specialist...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1990-05-01 00:00:00
abstract::Abraham Horwitz, MD, was a prominent leader in Public Health in the Americans. His career started as a clinician and researcher in infectious diseases, then as a teacher in two Chilean Universities, one of the organizers of the Public Health Service in Chile and, subsequently, a prominent staff member in the Pan Ameri...
journal_title:Revista medica de Chile
pub_type: 传,历史文章,杂志文章
doi:10.4067/s0034-98872001000400016
更新日期:2001-04-01 00:00:00
abstract:BACKGROUND:The risk of cardiovascular diseases is two to four times higher in diabetic patients. AIM:To study the severity of coronary disease and survival of patients with diabetes mellitus, compared to matched controls without diabetes. PATIENTS AND METHODS:A retrospective review of all coronary angiographies perfo...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:10.4067/s0034-98872004000300008
更新日期:2004-03-01 00:00:00
abstract::This is the speech pronounced by Dr Abraham Horwitz, Emeritus Professor of the University of Chile and Honorary Director of PAHO, during the academic act that celebrated the fiftieth anniversary of the Chilean Public Health School endowment. The school had a doctrinal and technical impact on Chilean health and decisiv...
journal_title:Revista medica de Chile
pub_type: 历史文章,杂志文章
doi:
更新日期:1994-09-01 00:00:00
abstract:BACKGROUND:Reproductive number (R0)-maps estimate risk zones of vector-borne diseases and geographical distribution changes under climate change. AIM:To map R0 aiming to estimate the epidemiological risk of Chagas disease in Chile, its distribution and possible changes due to the global climate change. MATERIAL AND M...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:10.4067/S0034-98872019000600683
更新日期:2019-06-01 00:00:00
abstract::We performed real time echotomographic studies in 203 patients with a clinical diagnosis of obstructive jaundice. All patients were operated on and a diagnosis of choledocholithiasis was established in 125. The same diagnosis had been made by echo in 69 of them for a 63% sensitivity rate. The specificity was 92% and t...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1989-11-01 00:00:00
abstract::Malignant Melanoma (MM) incidence rate is increasing faster than many other cancer at present time. Its epidemiological and clinical behavior varies within countries. We have studied 113 cases of cutaneous melanoma from 1982-1993, that represents until now the largest series of MM studied in Chile. Superficial Spreadi...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1994-08-01 00:00:00
abstract:BACKGROUND:Intrahepatic cholestasis of pregnancy (ICP) is a disease of unknown cause characterized by pruritus and biochemical cholestasis in the 3rd trimester of pregnancy. Its pathogenesis may be due to the interaction of abnormalities in the metabolism of estrogens and progesterone, while still unknown environmental...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:2000-01-01 00:00:00
abstract::One thousand women hospitalized at a maternity were surveyed after their delivery or abortion about their first sexual intercourse and pregnancy. Mean age at the first sexual intercourse was 18.7 years and only 9.2% used a contraceptive method in spite that 20% were not willing to become pregnant. The mean age of sexu...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1995-07-01 00:00:00
abstract::There is a close link between hypertension and atherosderosis. Hypertension causes atherosclerotic damage of several organs, called target organs and the risk factors for hypertension and atherosderosis are very similar. The risk of mortality associated to hypertension increases with blood pressure values below the cu...
journal_title:Revista medica de Chile
pub_type: 杂志文章,评审
doi:/S0034-98872010000300015
更新日期:2010-03-01 00:00:00
abstract::The administration of an angiotensin-converting enzyme (ACE) inhibitor transitorily reduces the GFR in a kidney with renal artery stenosis, effect that can be ascertained with scintigraphic studies using ACE inhibitors. We evaluated the clinical usefulness of captopril renography (CR) in the diagnosis of renovascular ...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1993-07-01 00:00:00
abstract::We studied 36 men and 94 women aged 60 to 85 years, without nutritional deficiencies or illness that could interfere with hematopoiesis, to characterize the normal limits of red and white blood cell counts. Lower limit of hemoglobin normal values were 132 g/l for men and 125 g/l for women. The corresponding figures fo...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1994-11-01 00:00:00
abstract:BACKGROUND:The Chilean Ministry of Health has been using standards for nutritional evaluation and weight gain recommendations during pregnancy in the last 25 years. In the meantime new standards have been developed. AIM:To study the combined influence of preconception maternal nutritional status and gestational weight...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:/S0034-98872011000600003
更新日期:2011-06-01 00:00:00
abstract:BACKGROUND:An important agent of food intoxication is Staphylococcus aureus, that is able to produce enterotoxins. AIM:To detect Staphylococcus aureus contamination in cafeteria food handlers of a Chilean University. SUBJECTS AND METHODS:Nose, throat, hands and nail samples from 87 food handlers were obtained for mic...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1996-09-01 00:00:00
abstract::Results of morbidity and medical care surveys performed in Santiago in 1993-94 are presented in this paper. The study has been done in an aleatory population sample of 4,700 people coming from 1,000 dwellings. Main results are as following: The Health National Fund (FONASA) is the most important financing medical care...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1995-01-01 00:00:00