[Early rheumatoid arthritis].

Abstract:

:This article reviews some key issues of early rheumatoid arthritis such as the dfficulties to recognize this condition during the first months after onset. Therefore, three reference diagnostic criteria have been proposed for any patient presenting with more than three simultaneously inflammed joints, involvement of metacarpophalangeal or proximal interphalangeal joints and morning stiffness lasting more than 30 minutes. Antibodies to cyclic citrullinated peptides are new markers that can be used for diagnosis. The immediate treatment during the "opportunity window" at the onset of inflammation may avoid the erosive joint damage. The use of synthetic or biological disease modifying medications, specially tumor necrosis factor alpha antagonists, also contribute to this purpose. Primary care physicians should be aware of the early signs of the disease to provide an adequate treatment and referral to specialists.

journal_name

Rev Med Chil

journal_title

Revista medica de Chile

authors

Massardo L

doi

10.4067/s0034-98872008001100015

subject

Has Abstract

pub_date

2008-11-01 00:00:00

pages

1468-75

issue

11

eissn

0034-9887

issn

0717-6163

journal_volume

136

pub_type

杂志文章,评审
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    authors: Whittle C,González P,Horvath E,Niedmann JP,Baldassare G,Seguel S,Mackinnon J

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    authors: Yulis J,Geny C,Levy R

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    doi:

    authors: Chuaqui R,Cuello M,Emmert-Buck M

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    authors: Medina E,Kaempffer AM,Cornejo E,Hernández E,Wall V

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    authors: Olmos A,Gajardo J,Lecannelier E,Seguel I,Lama A,Otero C,Fasce E

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    abstract::Master of internal Medicine is the highest award granted by the Chilean Society of Internal Medicine (Sociedad Médica de Santiago) to its members. This article outlines the sense and transcendence of this award and provides an abridged, certainly incomplete, data of the recipients since 1981 when this award was first ...

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    abstract:BACKGROUND:Maximal oxygen uptake is considered by the International Biological Programme as the international standard of cardiorespiratory adequacy and physical condition. AIM:To measure maximal oxygen uptake in normal Chilean subjects, to establish normal reference values. SUBJECTS AND METHODS:Maximal oxygen uptake...

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  • [Commercial reagents in the diagnosis of Chagas' disease].

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    authors: Astorga B,Herskovic P

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  • [HIV infection: recommendations for the management of asymptomatic adults and of various clinical syndromes].

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    authors: Wolff M,Northland R

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