Abstract:
:Amiodarone is a benzofuranic derivative widely used in cardiologic practice because of its excellent antiarrhythmic properties. Due to its high iodine content, it interferes with thyroid physiology and can cause either hyper or hypothyroidism. Amiodarone-induced hyperthyroidism should be considered as a serious complication since it develops in cardiac patients, the clinical diagnosis can be difficult and because conventional methods of therapy are said to be often ineffective. We analyze the outcome of 10 pts, chronically treated with Amiodarone (16-60 mo, mean 37.6 mo) who develop hyperthyroidism during the antiarrhythmic therapy. All patients had multinodular goiter. Overt clinical picture for thyrotoxicosis was seen in 7 of them and lab tests showed: rT3 = 101.1 +/- 14.9 ng/dl; T3 = 220.2 +/- 25 ng/dl; T4 = 15.6 +/- 1.9 micrograms/dl, TSH = 0.8 +/- 0.2 microU/ml and TRH response 0.0 microU/ml. Thyroid microsomal antibodies were negative in 3 pts studied. After Amiodarone was discontinued, patients were followed-up monthly. In 2, normalization of clinical and laboratory indexes were obtained at 40-60 d and no other medication was given. In the remaining, due to the intensity of clinical manifestations, PTU treatment was started (300 mg/d) After 4 mo, euthyroidism was achieved in 6 and it persisted after discontinuation of PTU has patient failed to respond to PTU, 131I was administered with excellent results. Patients have been followed-up up to 3 years after therapy without observing thyrotoxic relapses nor deterioration of their cardiological condition.2+ conventional therapies (PTU or 131I) have been, very effective.
journal_name
Rev Med Chiljournal_title
Revista medica de Chileauthors
Pineda G,Meruane J,Valenzuela MA,Bianchi Csubject
Has Abstractpub_date
1989-03-01 00:00:00pages
279-84issue
3eissn
0034-9887issn
0717-6163journal_volume
117pub_type
杂志文章abstract:BACKGROUND:Streptococcus agalactiae or group B streptococcus, GBS, is the leading cause of neonatal and maternal infections and an opportunistic pathogen in adults with underlying disease. In the last decade, a dramatic increase in the resistance of this microorganism to erythromycin and clindamycin has been observed. ...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:10.4067/s0034-98872004000500003
更新日期:2004-05-01 00:00:00
abstract:BACKGROUND:Multiauthorship and unjustified authorship have been documented in journals with wide international circulation but this has not been thoroughly studied in journals from developing countries. Revista Médica de Chile is published in Spanish and it contains about 40% of the clinical and biomedical manuscripts ...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:2002-12-01 00:00:00
abstract::The practice of Medicine is exposed to everyday's ethical ventures that, even though not fundamental in a philosophical scope, are most crucial given its incidence and consequences to accessibility and equity in health care. A very special perception must emerge to allow us looking for those situations where moral con...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1994-01-01 00:00:00
abstract::We report a 52 year old man with a pancreatic pseudocyst, that was admitted with severe abdominal pain, severe vomiting, fever and malaise. The clinical picture was considered secondary to a pseudocyst infection and the patient was operated, draining the infected cyst performing a necrosis surgery and pancreatojejunos...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:2001-01-01 00:00:00
abstract:BACKGROUND:Inferior vena cava (IVC) filters are used to prevent massive pulmonary embolism in cases where anticoagulation is contraindicated or has failed. It is usually implanted below the renal veins. In a few cases it is necessary to deploy the filter above them, with theoretical risk of secondary renal failure. AI...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:/S0034-98872008001200005
更新日期:2008-12-01 00:00:00
abstract::Gestational Diabetes is characterized by different degrees of glucose intolerance that produce a series of fetal and perinatal alterations. During many years, in those cases of gestational diabetes that did not respond to nutritional interventions, the use of insulin was a proven treatment to achieve metabolic control...
journal_title:Revista medica de Chile
pub_type: 杂志文章,评审
doi:/S0034-98872008000700015
更新日期:2008-07-01 00:00:00
abstract:BACKGROUND:Cellular immune mechanisms of the resistance to infection by T cruzi as well as the pathogenesis of Chagas disease are still controversial. AIM:To quantify and analyse the peripheral blood immune cells from chagasic and non chagasic patients by flow cytometry. PATIENTS AND METHODS:Peripheral blood samples ...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:2002-04-01 00:00:00
abstract::Heterozygous familial hypercholesterolemia affects one every 400 individuals, is caused by mutations in the LDL receptor gene and is associated with premature coronary artery disease. Nowadays, LDL cholesterol can be efficiently reduced with the new therapies to reduce blood lipids. We report a female patient who cons...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:10.4067/s0034-98872007000200011
更新日期:2007-02-01 00:00:00
abstract:BACKGROUND:On February 27, 2010 a powerful earthquake followed by a tsunami stroke Chile. The study of mortality during this emergency can provide important public health information. AIM:To describe the main characteristics of people who died during the earthquake and the following three months. MATERIAL AND METHODS...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:10.4067/S0034-98872012000600006
更新日期:2012-06-01 00:00:00
abstract:BACKGROUND:Osteoporotic hip fractures are devastating events in older women. There is a genetic modulation of bone phenotypic parameters including bone density (BMD) and bone fragility fractures. Vitamin D receptor (VDR) gene polymorphisms explain a small part of the genetic influence on BMD, whereas their effect on fr...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:/S0034-98872008000400008
更新日期:2008-04-01 00:00:00
abstract:BACKGROUND:Bottled water consumption has currently increased and their fluoride (F) concentration may not be ideal in terms of caries benefit or risk of fluorosis. While low concentrations would have little anticaries effect, high F concentration would increase the risk of dental fluorosis. AIM:To measure F concentrat...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:10.4067/S0034-98872014000500011
更新日期:2014-05-01 00:00:00
abstract::Lung computed tomography (CT) is being used increasingly to assess lung morphology in patients on mechanical ventilation. Lung CT under known levels of airway pressure (dynamic CT) can also assess the response of lung parenchyma to ventilatory therapy. We report a patient with acute respiratory distress syndrome secon...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:2003-02-01 00:00:00
abstract::We analyzed retrospectively the clinical course and prognosis of 565 consecutive patients with acute myocardial infarction (AMI), 117 of them with a previous history of diabetes mellitus. Male/female ration was 7.9/2.1 in non diabetics and 7.0/3.0 in diabetics (p < 0.03). Incidence of hypertension and hyperlipidemia w...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1993-06-01 00:00:00
abstract::Considering that a high proportion of the Chilean general population smokes, the Chilean Society of Respiratory Diseases in collaboration with the Chilean Societies of Cardiology and, Endocrinology and Diabetes, formed an interdisciplinary group, who issued a set of recommendations for the treatment of the smoker, met...
journal_title:Revista medica de Chile
pub_type: 杂志文章,实务指引
doi:10.4067/s0034-98872017001101471
更新日期:2017-11-01 00:00:00
abstract::Aspirin use is necessary after a coronary angioplasty. It should not be used in patients with a history of hypersensitivity. However, rapid desensitization protocols have been reported to allow its use in such patients. One of these protocols consists in the administration of progressive doses of aspirin, from 1 to 10...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:10.4067/S0034-98872013000200016
更新日期:2013-02-01 00:00:00
abstract::We report a 56 years-old man presenting with chest pain with exercise, seven years after an orthotopic heart transplant. A coronary angiography showed an atherosclerotic lesion in the common left main coronary artery with more than 90% obstruction. The lesion was successfully treated with a transluminal angioplasty wi...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:/S0034-98872007001200012
更新日期:2007-12-01 00:00:00
abstract:BACKGROUND:During the last few years, multiple new medical schools have emerged in Chile, associated to the constant preoccupation to provide a good quality medical care. This created the need to evaluate medical training programs and to open a discussion about the attributes that a good physician should have. AIM:To ...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:10.4067/s0034-98872006000800001
更新日期:2006-08-01 00:00:00
abstract::Edgar Allan Poe, one of the best American storytellers and poets, suffered an episodic behaviour disorder partially triggered by alcohol and opiate use. Much confusion still exists about the last days of his turbulent life and the cause of his death at an early age. Different etiologies have been proposed to explain h...
journal_title:Revista medica de Chile
pub_type: 传,历史文章,杂志文章
doi:10.4067/s0034-98872007000900019
更新日期:2007-09-01 00:00:00
abstract:BACKGROUND:Title revalidation of foreign medical graduates to practice medicine in Chile is a complex and expensive process. According to the legislation they are required to approve the Unique National Exam of Medical Knowledge (EUNACOM), which has a theoretical and a practical section. AIM:To demonstrate that a coll...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:10.4067/s0034-98872018000200232
更新日期:2018-02-01 00:00:00
abstract::Leptospirosis is a world-spread zoonosis that is incidentally acquired by humans. It causes a diphasic febrile illness in which the Weil syndrome is its severest form, with renal, hepatic, clotting and central nervous system involvement. We report a 73 years old male, that was admitted to an intensive care unit with m...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1996-03-01 00:00:00
abstract:BACKGROUND:Malnutrition has been strongly associated with morbidity and mortality in hemodialysis patients. In the other hand, dialysis allows a nutritional improvement in patients with more than 12 months in dialysis. AIM:To study the prevalence of malnutrition among patients in hemodialysis. PATIENTS AND METHODS:We...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:2001-05-01 00:00:00
abstract:BACKGROUND:In patients with colorectal carcinoma, insertions or deletions of short sequences of DNA, a phenomenon called microsatellite instability, are observed. AIM:To look for microsatellite instability and mutations of MLH1 and MSH2 gene mutations in patients with colorectal carcinoma. MATERIAL AND METHODS:Ten pa...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:10.4067/s0034-98872006001000002
更新日期:2006-10-01 00:00:00
abstract::Signet ring gallbladder carcinoma is a rare aggressive variant of mucinous adenocarcinoma with poor prognosis. Positron emission tomography/computed tomography (PET/CT) with Fluor18 deoxyglucose (F18-FDG) is a useful tool in the staging of gallbladder cancer. We report a 68 years old man with a surgically resected acu...
journal_title:Revista medica de Chile
pub_type:
doi:10.4067/S0034-98872017000400013
更新日期:2017-04-01 00:00:00
abstract::Prader-Willi syndrome is an uncommon multisystem genetic disorder caused by defects of chromosome 15 (15qll-ql3), often due to deletions or uniparental disomy The syndrome is characterized by neonatal hypotonia, dysmorphic facial features, short stature, motor and mental disabilities, behavioral changes, hyperphagia, ...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:/S0034-98872009000200012
更新日期:2009-02-01 00:00:00
abstract::Protective immunity against rotavirus infection is directed against antigenic epitopes on the outer capsid proteins VP7 and VP4. The aim of this study was to characterize the VP7 and VP4 antigenic types circulating in different hospital areas of Santiago, Chile, over different time periods. Between April 1993 and Apri...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1995-05-01 00:00:00
abstract::To study the effect of old age on phenytoin pharmacokinetics, twelve young and nine old adults aged 21.7 +/- 1.8 and 71.8 +/- 4.9 years respectively, were studied. No significant differences of phenytoin indicating the drug distribution and elimination does not change with aging. After oral administration, significant...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1992-10-01 00:00:00
abstract::Andrés Bello, a Venezuelan intellectual arrived in Chile in 1829. He had a decisive influence on the development of natural sciences and medical sciences in this country. The first formal teaching program in Medicine appeared in 1833, with few students due to the low social prestige of Medicine at that time. The Facul...
journal_title:Revista medica de Chile
pub_type: 传,历史文章,杂志文章
doi:
更新日期:1991-11-01 00:00:00
abstract:BACKGROUND:Laparoscopic esophagomyotomy is becoming a good alternative to pneumatic dilatation, injection of botulinic toxin or classical surgery in the treatment of achalasia. AIM:To report the results of laparoscopic esophagomyotomy in patients with achalasia. PATIENTS AND METHODS:Nineteen patients with achalasia, ...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:2001-10-01 00:00:00
abstract::Stem cells have drawn extraordinary attention from scientists and the general public due to their potential to generate effective therapies for incurable diseases. At the same time, the production of embryonic stem cells involves a serious ethical issue concerning the destruction of human embryos. Although adult stem ...
journal_title:Revista medica de Chile
pub_type: 杂志文章,评审
doi:10.4067/S0034-98872013000800010
更新日期:2013-08-01 00:00:00
abstract::Bronchogenic cysts are congenital malformations of the tracheo-bronchial tree usually located intrathoraxically. We report a 44 years old male with a bronchogenic cyst located exceptionally in the pre tracheal anterior cervical region, simulating a thyroid lesion. ...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1999-08-01 00:00:00