Persantine Aspirin Trial in cerebral ischemia. Part II: Endpoint results. The American-Canadian Co-Operative Study group.

abstract：BACKGROUND AND PURPOSE:The present study determines associations between early blood pressure (BP) variability and stroke outcomes after intravenous thrombolysis. METHODS:In 527 stroke patients receiving intravenous alteplase (0.6 mg/kg), BP was measured 8 times within the first 25 hours. BP variability was determined...

journal_title：Stroke

authors： Endo K,Kario K,Koga M,Nakagawara J,Shiokawa Y,Yamagami H,Furui E,Kimura K,Hasegawa Y,Okada Y,Okuda S,Namekawa M,Miyagi T,Osaki M,Minematsu K,Toyoda K

更新日期：2013-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The ankle-brachial index (ABI) is a fast, cheap, noninvasive indicator of atherosclerotic burden that may also be a predictor of stroke recurrence. In this systematic review and meta-analysis, we sought to explore ABI's merit as a marker for stroke recurrence and vascular risk by synthesizing the...

journal_title：Stroke

authors： Hong JB,Leonards CO,Endres M,Siegerink B,Liman TG

更新日期：2016-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Recombinant activated factor VII (rFVIIa) reduces hematoma expansion and improves outcome after intracerebral hemorrhage (ICH), with an apparent increase in nonfatal thromboembolic events (TEs) with higher doses. Despite low incidences of such events in rFVIIa-treated hemophiliacs, the frequency ...

journal_title：Stroke

authors： Diringer MN,Skolnick BE,Mayer SA,Steiner T,Davis SM,Brun NC,Broderick JP

更新日期：2008-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Central nervous system serotonergic neurotransmission appears to play a role in mood disorders, eating habits, and sleep, and also modulates blood pressure and metabolism. This investigation tested a hypothesized association between central serotonergic functioning and preclinical atherosclerosis...

journal_title：Stroke

authors： Muldoon MF,Mackey RH,Sutton-Tyrrell K,Flory JD,Pollock BG,Manuck SB

更新日期：2007-08-01 00:00:00

abstract：:The protective properties of PY 108-068 against ischemic disturbances in the brain were investigated in vitro and in vivo. The calcium antagonistic effects were demonstrated on isolated, calcium-loaded arterial rings of feline cerebral arteries. Determination of brain tissue oxygenation with pO2 microelectrodes showed...

journal_title：Stroke

authors： Wiernsperger N,Gygax P,Hofmann A

更新日期：1984-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Transcranial color-coded sonography is a new development in noninvasive cerebral vascular imaging. Reference data using this technique are described. METHODS:Blood velocities and pulsatility and resistance indices were determined in the anterior cerebral, middle cerebral, posterior cerebral, ver...

journal_title：Stroke

authors： Martin PJ,Evans DH,Naylor AR

更新日期：1994-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Numerous studies have demonstrated an association between acute cardiac events, cerebrovascular accidents, and cocaine use. The underlying mechanisms leading to these complications have not been well defined. Using various in vitro model systems, it has been reported that cocaine, up to or greate...

journal_title：Stroke

authors： Jennings LK,White MM,Sauer CM,Mauer AM,Robertson JT

更新日期：1993-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Stent placement has been applied in small case series as a rescue therapy in combination with different thrombolytic agents, percutaneous balloon angioplasty (PTA), and mechanical thromboembolectomy (MT) in acute stroke treatment. These studies report a considerable mortality and a high rate of i...

journal_title：Stroke

authors： Brekenfeld C,Schroth G,Mattle HP,Do DD,Remonda L,Mordasini P,Arnold M,Nedeltchev K,Meier N,Gralla J

更新日期：2009-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Stroke mortality is decreasing in Sweden, as is the case in other Western European countries. However, both decreases and increases have been reported in Sweden for persons younger than age 65 years. The aim of this study was to compare the incidence of stroke in Sweden between the periods 1989 a...

journal_title：Stroke

authors： Medin J,Nordlund A,Ekberg K,Swedish Hospital Discharge Register.

更新日期：2004-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Abnormalities in endogenous fibrinolysis are associated with an increased risk for stroke in men and older adults. We tested the hypothesis that elevated plasma tissue plasminogen activator (tPA) antigen, a marker for impaired endogenous fibrinolysis, is an independent risk factor for stroke in y...

journal_title：Stroke

authors： Macko RF,Kittner SJ,Epstein A,Cox DK,Wozniak MA,Wityk RJ,Stern BJ,Sloan MA,Sherwin R,Price TR,McCarter RJ,Johnson CJ,Earley CJ,Buchholz DW,Stolley PD

更新日期：1999-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Leukocytes contribute to cerebral ischemia-reperfusion injury. However, few experimental models examine both in vivo behavior of leukocytes and microvascular rheology after stroke. The purpose of the present study was to characterize patterns of leukocyte accumulation in the cerebral microcircula...

journal_title：Stroke

authors： Ritter LS,Orozco JA,Coull BM,McDonagh PF,Rosenblum WI

更新日期：2000-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:We tested the hypothesis that circulating microRNAs (miRNAs) present in plasma might display a specific signature in patients with intracerebral hemorrhage. METHODS:Global miRNA profiles were determined with the Agilent Human miRNA Microarray platform, and validated by quantitative polymerase ch...

journal_title：Stroke

authors： Guo D,Liu J,Wang W,Hao F,Sun X,Wu X,Bu P,Zhang Y,Liu Y,Liu F,Zhang Q,Jiang F

更新日期：2013-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Interhemispheric inhibition via the corpus callosum has been proposed as an exacerbating factor in outcome from stroke. METHODS:We measured infarct volume and behavioral outcome after middle cerebral artery occlusion in callosotomized rats and acallosal mice. RESULTS:Neither callosotomy in rats...

journal_title：Stroke

authors： Jin K,Xie L,Sun F,Mao X,Greenberg DA

更新日期：2011-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Approximately one fourth of stroke occur during sleep. Despite the clinical and radiological similarities between wake-up stroke (WUS) and non-WUS, the functional outcomes of WUS are largely unknown. METHODS:This retrospective analysis reviewed 2289 consecutive patients with acute ischemic strok...

journal_title：Stroke

authors： Kim BJ,Lee SH,Shin CW,Ryu WS,Kim CK,Yoon BW

更新日期：2011-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Chronic kidney disease may increase the risk for ischemic stroke or systemic embolism in patients with nonvalular atrial fibrillation (AF). We conducted a meta-analysis to summarize all published studies to investigate the link between chronic kidney disease and risk of thromboembolic events in A...

journal_title：Stroke

authors： Zeng WT,Sun XT,Tang K,Mei WY,Liu LJ,Xu Q,Cheng YJ

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Acute ischemic stroke in humans is associated with profound alterations in the immune system. Hallmarks of this stroke-induced immunodepression syndrome are: lymphocytopenia, impairment of T helper cell and monocyte function. We studied which stroke-specific factors predict these immunologic alte...

journal_title：Stroke

authors： Hug A,Dalpke A,Wieczorek N,Giese T,Lorenz A,Auffarth G,Liesz A,Veltkamp R

更新日期：2009-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Hypertension control is a cornerstone of preventive treatment in patients at risk for cerebral attack. The aim of this study was to analyze hypertension management in secondary prevention of stroke as compared with patients in secondary prevention of myocardial infarction (MI). METHODS:The ECLAT...

journal_title：Stroke

authors： Amar J,Cambou JP,Touzé E,Bongard V,Jullien G,Vahanian A,Coppé G,Mas JL,ECLAT1 Study Investigators.

更新日期：2004-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:20% of ischemic stroke is in the posterior circulation, but there is little prospective data on early recurrent stroke risk and whether vertebrobasilar stenosis predicts a high recurrence risk. This natural history data are important as it is technically possible to stent such lesions. Contrast e...

journal_title：Stroke

authors： Gulli G,Khan S,Markus HS

更新日期：2009-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The greater mortality and residual physical impairments among black stroke patients may be attributable to differential utilization of rehabilitation services. This report examines, within an equal-access healthcare system, racial differences in time to initiation of stroke rehabilitation service...

journal_title：Stroke

authors： Horner RD,Swanson JW,Bosworth HB,Matchar DB,VA Acute Stroke (VAST) Study Team.

更新日期：2003-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The purpose of this work was to investigate how stroke rehabilitation professionals understand the concept of motivation and the ways that they use this concept in their clinical practice. METHODS:This qualitative study used semistructured, in-depth interviews with the professionals working in t...

journal_title：Stroke

authors： Maclean N,Pound P,Wolfe C,Rudd A

更新日期：2002-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The role of uric acid as a risk factor for myocardial infarction is controversial, and little is known about its role as a risk factor for stroke. Recent evidence suggests that uric acid may be an important causal agent in cardiovascular disease, for example, by inducing renal disease and hence h...

journal_title：Stroke

authors： Bos MJ,Koudstaal PJ,Hofman A,Witteman JC,Breteler MM

更新日期：2006-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The rate of nitric oxide (NO) generation from nitrite is linearly dependent on reductions in oxygen and pH levels. Recently, nitrite-derived NO has been reported to exert a profound protection against liver and heart ischemia-reperfusion injury. In this study, we hypothesized that nitrite would b...

journal_title：Stroke

authors： Jung KH,Chu K,Ko SY,Lee ST,Sinn DI,Park DK,Kim JM,Song EC,Kim M,Roh JK

更新日期：2006-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The clinical syndrome of transient ischemic attacks is accompanied in a significant percentage of patients by brain lesions or neuroimaging abnormalities whose structural counterparts have not been defined. The objective of this study was to analyze, in an experimental model of short-term (< 25 m...

journal_title：Stroke

authors： Garcia JH,Liu KF,Ye ZR,Gutierrez JA

更新日期：1997-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Recent evidence suggests that physiological changes in the concentration of endogenous estrogens may influence stroke outcome. The purpose of this study was to determine a menstrual cycle-related profile of blood flow through the carotid arteries and its correlation with estrogen concentration. ...

journal_title：Stroke

authors： Krejza J,Mariak Z,Huba M,Wolczynski S,Lewko J

更新日期：2001-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Pial arterioles transiently dilate during cortical spreading depression (CSD), although the mechanisms are unclear. We tested the hypothesis that increased production of nitric oxide (NO) promotes arteriolar dilation. METHODS:Urethane-anesthetized rabbits were equipped with cranial windows, and ...

journal_title：Stroke

authors： Colonna DM,Meng W,Deal DD,Busija DW

更新日期：1994-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Cerebrovascular reserve (CVR) by both transcranial Doppler ultrasonography (TCD) and quantitative cerebral blood flow (CBF) can identify subgroups of patients at increased risk for stroke. A direct comparison of CVR measurements obtained with both technologies in patients with cerebrovascular occ...

journal_title：Stroke

authors： Pindzola RR,Balzer JR,Nemoto EM,Goldstein S,Yonas H

更新日期：2001-08-01 00:00:00

abstract：:Forty-five patients with symptomatic (20 with transient ischemic attack, 25 with minor stroke) greater than or equal to 75% stenosis of the cervical internal carotid artery had no endarterectomy and received only medical therapy because the surgical risks (severe cardiac disease, chronic obstructive pulmonary disease,...

journal_title：Stroke

authors： Bogousslavsky J,Despland PA,Regli F

更新日期：1988-01-01 00:00:00

abstract：:Results from 1,039 combined cervical and transcranial Doppler examinations are reported. Satisfactory transcranial signals were not found in 2.7% of the cases. Compared with angiography, the accuracy of transcranial criteria in assessing collateral flow over the circle of Willis was 94 and 88% for anterior and posteri...

journal_title：Stroke

authors： Grolimund P,Seiler RW,Aaslid R,Huber P,Zurbruegg H

更新日期：1987-11-01 00:00:00

abstract：:In an attempt to elucidate the mechanism by which hypertension acts as a risk factor for major non-haemorrhagic stroke, its effect on the prevalence of carotid atheroma has been studied angiographically. The carotid angiograms of 269 patients with cerebral tumours have been reviewed for evidence of coincidental athero...

journal_title：Stroke

authors： Harrison MJ,Wilson LA

更新日期：1983-07-01 00:00:00

abstract：:Cerebral cortical blood flow was measured in rabbits with the hydrogen clearance technique. The reactivity to CO2, tested by changing the end tidal CO2 (ETCO2) in steps from 2 to 6 volumes %, was highly dependent on the kind of anesthesia, being greatest under halothane and least under nitrous oxide. Reactivity to CO2...

journal_title：Stroke

authors： Scremin OU,Rubinstein EH,Sonnenschein RR

更新日期：1978-03-01 00:00:00