Abstract:
:This study describes the velocity characteristics of left ventricular and aortic outflow in 25 patients with hypertrophic "obstructive" cardiomyopathy. Systematic pulsed and continuous wave Doppler analysis combined with phonocardiography and M-mode echocardiography was used to establish the pattern and timing of outflow in the basal and provoked states. This analysis suggests that 1) the high velocity left ventricular outflow jet can be reliably discriminated from both aortic flow and the jet of mitral regurgitation using Doppler ultrasound; 2) the Doppler velocity contour responds in a characteristic fashion to provocative influences including extrasystole and Valsalva maneuver; 3) the onset of mitral regurgitation occurs well before detectable systolic anterior motion of the mitral valve; 4) left ventricular flow velocities are elevated at the onset of systolic anterior motion of the mitral valve, suggesting a significant contribution of the Venturi effect in displacing the leaflets and chordae; 5) the high velocities of the outflow jets are largely dissipated by the time flow reaches the aortic valve; and 6) late systolic flow in the ascending aorta is nonuniform, with formation of distinct eddies that may contribute to "preclosure" of the aortic valve.
journal_name
J Am Coll Cardioljournal_title
Journal of the American College of Cardiologyauthors
Yock PG,Hatle L,Popp RLdoi
10.1016/s0735-1097(86)80381-3subject
Has Abstractpub_date
1986-11-01 00:00:00pages
1047-58issue
5eissn
0735-1097issn
1558-3597pii
S0735-1097(86)80381-3journal_volume
8pub_type
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