Use of color kinesis for evaluation of left ventricular filling in patients with dilated cardiomyopathy and mitral regurgitation.

Abstract:

OBJECTIVES:We tested the feasibility of using analysis of color kinesis images to objectively assess global and regional left ventricular (LV) diastolic function in patients with dilated cardiomyopathy (DCM). In addition, the ability of this technique to track drug-induced changes on LV diastolic properties was studied. BACKGROUND:Diastolic dysfunction contributes to symptomatology in patients with DCM. The assessment of LV diastolic function using conventional Doppler echocardiography is indirect and is confounded by multiple variables. Moreover, the noninvasive evaluation of regional diastolic properties is difficult. In contrast, color kinesis directly tracks and color-encodes regional diastolic endocardial motion. METHODS:We studied 24 patients with DCM and mitral regurgitation (MR) and 24 age-matched normal subjects. Transmitral and pulmonary vein flow velocities were measured using pulsed Doppler echocardiography. Diastolic color kinesis images were used to calculate indexes of magnitude and timing of global and regional diastolic function. Diastolic asynchrony was evaluated in different subgroups of patients with DCM. The effects of drug infusions (nitroprusside and dobutamine) were also studied. RESULTS:Color kinesis indexes of global diastolic function showed significant differences between patients with DCM and normal subjects. Compared with Doppler indexes, color kinesis was less confounded by MR and was capable of differentiating between drug-induced lusitropic and vasodilator effects. Diastolic asynchrony was increased in patients with DCM and severe MR. CONCLUSIONS:Quantitative analysis of global and regional LV diastolic function in patients with DCM using color kinesis is feasible.

journal_name

J Am Coll Cardiol

authors

Godoy IE,Mor-Avi V,Weinert L,Vignon P,Korcarz C,Spencer KT,Lang RM

doi

10.1016/s0735-1097(98)00144-2

subject

Has Abstract

pub_date

1998-06-01 00:00:00

pages

1598-606

issue

7

eissn

0735-1097

issn

1558-3597

pii

S0735-1097(98)00144-2

journal_volume

31

pub_type

杂志文章
  • Russek Lecture. Must cardiology lose its heart?

    abstract::Regulations and restrictions imposed by external agencies are forcing cardiologists into an unnatural self-protective and defensive posture against their patients. The key to breaking the pattern of mutual skepticism and mistrust lies in returning the focus to its rightful place: the patients' needs. Thus, payment sys...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章

    doi:10.1016/0735-1097(92)90630-6

    authors: Gorlin R

    更新日期:1992-06-01 00:00:00

  • ANKRD1, the gene encoding cardiac ankyrin repeat protein, is a novel dilated cardiomyopathy gene.

    abstract:OBJECTIVES:We evaluated ankyrin repeat domain 1 (ANKRD1), the gene encoding cardiac ankyrin repeat protein (CARP), as a novel candidate gene for dilated cardiomyopathy (DCM) through mutation analysis of a cohort of familial or idiopathic DCM patients, based on the hypothesis that inherited dysfunction of mechanical str...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章

    doi:10.1016/j.jacc.2009.02.076

    authors: Moulik M,Vatta M,Witt SH,Arola AM,Murphy RT,McKenna WJ,Boriek AM,Oka K,Labeit S,Bowles NE,Arimura T,Kimura A,Towbin JA

    更新日期:2009-07-21 00:00:00

  • Disposition of the atrioventricular conduction tissues in the heart with isomerism of the atrial appendages: its relation to congenital complete heart block.

    abstract:OBJECTIVES:Our goal was to compare histologically the mechanisms producing congenital complete heart block in normally structured hearts and in hearts with isomerism of the atrial appendages. BACKGROUND:It is known that several different histologic patterns can underscore the existence of congenital complete heart blo...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章

    doi:10.1016/0735-1097(92)90191-o

    authors: Ho SY,Fagg N,Anderson RH,Cook A,Allan L

    更新日期:1992-10-01 00:00:00

  • Accurate noninvasive quantitation of blood flow, cross-sectional lumen vessel area and wall shear stress by three-dimensional paraboloid modeling of magnetic resonance imaging velocity data.

    abstract:OBJECTIVES:We present a new method in which a priori knowledge of the blood velocity fields within the boundary layer at the vessel wall, combined with acquisition of high resolution magnetic resonance imaging (MRI) blood velocity data, allow exact modeling at the subpixel level. BACKGROUND:Methods are lacking for acc...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章

    doi:10.1016/s0735-1097(98)00207-1

    authors: Oyre S,Ringgaard S,Kozerke S,Paaske WP,Erlandsen M,Boesiger P,Pedersen EM

    更新日期:1998-07-01 00:00:00

  • Use of electrophysiologic testing in patients with nonsustained ventricular tachycardia: prognostic and therapeutic implications.

    abstract::Forty patients with coronary artery disease and nonsustained ventricular tachycardia on ambulatory electrocardiographic monitoring underwent programmed electrical stimulation. In 22 patients, monomorphic ventricular tachycardia was induced at baseline drug-free electrophysiologic testing; 9 of these patients subsequen...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章

    doi:10.1016/0735-1097(89)90066-1

    authors: Klein RC,Machell C

    更新日期:1989-07-01 00:00:00

  • Relation between volume of exercise and clinical outcomes in patients with heart failure.

    abstract:OBJECTIVES:This study determined whether greater volumes of exercise were associated with greater reductions in clinical events. BACKGROUND:The HF-ACTION (Heart Failure: A Controlled Trial Investigating Outcomes of Exercise Training) trial showed that among patients with heart failure (HF), regular exercise confers a ...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.jacc.2012.08.958

    authors: Keteyian SJ,Leifer ES,Houston-Miller N,Kraus WE,Brawner CA,O'Connor CM,Whellan DJ,Cooper LS,Fleg JL,Kitzman DW,Cohen-Solal A,Blumenthal JA,Rendall DS,Piña IL,HF-ACTION Investigators.

    更新日期:2012-11-06 00:00:00

  • Impact of body weight and extreme obesity on the presentation, treatment, and in-hospital outcomes of 50,149 patients with ST-Segment elevation myocardial infarction results from the NCDR (National Cardiovascular Data Registry).

    abstract:OBJECTIVES:The aim of this study was to assess the impact of extreme (class III) obesity (body mass index [BMI] ≥40 kg/m(2)) on care and outcomes in patients with ST-segment elevation myocardial infarction (STEMI). BACKGROUND:Although its prevalence is increasing rapidly, little is known about the impact of extreme ob...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章

    doi:10.1016/j.jacc.2011.09.030

    authors: Das SR,Alexander KP,Chen AY,Powell-Wiley TM,Diercks DB,Peterson ED,Roe MT,de Lemos JA

    更新日期:2011-12-13 00:00:00

  • Long-term outcomes of older diabetic patients after percutaneous coronary stenting in the United States: a report from the National Cardiovascular Data Registry, 2004 to 2008.

    abstract:OBJECTIVES:The purpose of this study was to characterize long-term outcomes of percutaneous coronary intervention (PCI) in elderly diabetic patients in routine practice. BACKGROUND:Although drug-eluting stent (DES) implantation in diabetic patients is common practice, pivotal randomized trials enrolled <2,500 diabetic...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章,多中心研究

    doi:10.1016/j.jacc.2012.08.993

    authors: Hillegass WB,Patel MR,Klein LW,Gurm HS,Brennan JM,Anstrom KJ,Dai D,Eisenstein EL,Peterson ED,Messenger JC,Douglas PS

    更新日期:2012-12-04 00:00:00

  • A randomized trial to evaluate the relative protection against post-percutaneous coronary intervention microvascular dysfunction, ischemia, and inflammation among antiplatelet and antithrombotic agents: the PROTECT-TIMI-30 trial.

    abstract:OBJECTIVES:The goal of this study was to evaluate glycoprotein IIb/IIIa inhibition with eptifibatide when administered with indirect thrombin inhibition as compared with monotherapy with direct thrombin inhibition with bivalirudin among patients with non-ST-segment elevation acute coronary syndromes (ACS). BACKGROUND:...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.jacc.2005.12.077

    authors: Gibson CM,Morrow DA,Murphy SA,Palabrica TM,Jennings LK,Stone PH,Lui HH,Bulle T,Lakkis N,Kovach R,Cohen DJ,Fish P,McCabe CH,Braunwald E,TIMI Study Group.

    更新日期:2006-06-20 00:00:00

  • Skeletal muscle response to short endurance training in heart transplant recipients.

    abstract:OBJECTIVES:We sought to examine the effects of endurance training on the ultrastructural characteristics of skeletal muscle in heart transplant recipients (HTRs) and age-matched control subjects (C). BACKGROUND:Deconditioning is one of the factors involved in the peripheral limitation of exercise capacity of HTRs, and...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章

    doi:10.1016/s0735-1097(98)00227-7

    authors: Lampert E,Mettauer B,Hoppeler H,Charloux A,Charpentier A,Lonsdorfer J

    更新日期:1998-08-01 00:00:00

  • Clinical and genetic issues in familial dilated cardiomyopathy.

    abstract::Idiopathic dilated cardiomyopathy (IDC) is characterized by left ventricular dilatation and systolic dysfunction after known causes have been excluded. Idiopathic dilated cardiomyopathy occurring in families, or familial dilated cardiomyopathy (FDC), may occur in 20% to 50% of IDC cases. Sixteen genes have been shown ...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章,评审

    doi:10.1016/j.jacc.2004.11.066

    authors: Burkett EL,Hershberger RE

    更新日期:2005-04-05 00:00:00

  • Human ventricular unloading induces cardiomyocyte proliferation.

    abstract:BACKGROUND:The adult mammalian heart is incapable of meaningful regeneration after substantial cardiomyocyte loss, primarily due to the inability of adult cardiomyocytes to divide. Our group recently showed that mitochondria-mediated oxidative DNA damage is an important regulator of postnatal cardiomyocyte cell cycle a...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章

    doi:10.1016/j.jacc.2014.12.027

    authors: Canseco DC,Kimura W,Garg S,Mukherjee S,Bhattacharya S,Abdisalaam S,Das S,Asaithamby A,Mammen PP,Sadek HA

    更新日期:2015-03-10 00:00:00

  • Left ventricular remodeling with carvedilol in patients with congestive heart failure due to ischemic heart disease. Australia-New Zealand Heart Failure Research Collaborative Group.

    abstract:OBJECTIVES:The aim of this study, a substudy of the Australia-New Zealand trial of carvedilol in patients with heart failure due to ischemic heart disease, was to determine the effects of this treatment on left ventricular size and function with the use of quantitative two-dimensional (2D) echocardiography. BACKGROUND...

    journal_title:Journal of the American College of Cardiology

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.1016/s0735-1097(97)00012-0

    authors: Doughty RN,Whalley GA,Gamble G,MacMahon S,Sharpe N

    更新日期:1997-04-01 00:00:00

  • Physical activity reduces systemic blood pressure and improves early markers of atherosclerosis in pre-pubertal obese children.

    abstract:OBJECTIVES:The aim of this study was to determine the effects of physical activity on systemic blood pressure (BP) and early markers of atherosclerosis in pre-pubertal obese children. BACKGROUND:Hypertension and endothelial dysfunction are premature complications of obesity. METHODS:We performed a 3-month randomized ...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.jacc.2009.08.030

    authors: Farpour-Lambert NJ,Aggoun Y,Marchand LM,Martin XE,Herrmann FR,Beghetti M

    更新日期:2009-12-15 00:00:00

  • Multislice computed tomography versus intracardiac echocardiography to evaluate the pulmonary veins before radiofrequency catheter ablation of atrial fibrillation: a head-to-head comparison.

    abstract:OBJECTIVES:The purpose of this study was to perform a head-to-head comparison between multislice computed tomography (MSCT) and intracardiac echocardiography (ICE). BACKGROUND:Different imaging techniques have been used to visualize the pulmonary veins (PV) before radiofrequency ablation of atrial fibrillation. METHO...

    journal_title:Journal of the American College of Cardiology

    pub_type: 临床试验,杂志文章

    doi:10.1016/j.jacc.2004.10.040

    authors: Jongbloed MR,Bax JJ,Lamb HJ,Dirksen MS,Zeppenfeld K,van der Wall EE,de Roos A,Schalij MJ

    更新日期:2005-02-01 00:00:00

  • Use of two-dimensional echocardiography during transseptal cardiac catheterization.

    abstract::Inadvertent puncture of the intrapericardial aorta is a serious complication of transseptal catheterization. Two-dimensional echocardiography allows delineation and spatial resolution of the aorta and interatrial septum. Thirteen patients underwent transseptal catheterization with simultaneous monitoring of needle and...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章

    doi:10.1016/s0735-1097(84)80234-x

    authors: Kronzon I,Glassman E,Cohen M,Winer H

    更新日期:1984-08-01 00:00:00

  • Anisoylated plasminogen streptokinase activator complex in acute myocardial infarction: a placebo-controlled arteriographic coronary recanalization study.

    abstract::Anisoylated plasminogen streptokinase activator complex (APSAC) is a new thrombolytic agent that is of interest because of its ease of administration as an intravenous bolus injection. This report describes the first double-blind, placebo-controlled evaluation of intravenous APSAC for coronary recanalization in acute ...

    journal_title:Journal of the American College of Cardiology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/s0735-1097(87)80181-x

    authors: Timmis AD,Griffin B,Crick JC,Sowton E

    更新日期:1987-07-01 00:00:00

  • Sustained ventricular tachyarrhythmias during the early postinfarction period: electrophysiologic findings and prognosis for survival.

    abstract::Forty patients with sustained tachycardia occurring 3 to 65 days after myocardial infarction underwent programmed ventricular stimulation within 3 months of the infarction. Patients were characterized clinically by a complicated initial 48 hours of hospitalization for their acute infarction (85% of study group). The d...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章

    doi:10.1016/s0735-1097(83)80159-4

    authors: Marchlinski FE,Waxman HL,Buxton AE,Josephson ME

    更新日期:1983-08-01 00:00:00

  • Embolic potential of left ventricular thrombus after myocardial infarction: a two-dimensional echocardiographic study of 119 patients.

    abstract::Left ventricular thrombus complicating myocardial infarction was diagnosed by two-dimensional echocardiography in 119 patients. The infarct site was anterior in 98 patients and inferior in 11. Systemic embolism occurred in 26 patients (stroke in 18, lower limb embolism in 7 and mesenteric embolism in 1). A protruding ...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章

    doi:10.1016/s0735-1097(85)80336-3

    authors: Visser CA,Kan G,Meltzer RS,Dunning AJ,Roelandt J

    更新日期:1985-06-01 00:00:00

  • Scintigraphic assessment of sympathetic innervation after transmural versus nontransmural myocardial infarction.

    abstract::To evaluate the feasibility of detecting denervated myocardium in the infarcted canine heart, the distribution of sympathetic nerve endings using I-123 metaiodobenzylguanidine (MIBG) was compared with the distribution of perfusion using thallium-201, with the aid of color-coded computer functional map in 16 dogs. Twel...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章

    doi:10.1016/s0735-1097(10)80156-1

    authors: Dae MW,Herre JM,O'Connell JW,Botvinick EH,Newman D,Munoz L

    更新日期:1991-05-01 00:00:00

  • Maternal Overweight and Obesity and Risk of Congenital Heart Defects.

    abstract:BACKGROUND:Congenital heart defects are more frequent in offspring of mothers with overweight or obesity. However, associations between maternal overweight and obesity, and risks of complex and specific heart defects are not clear. OBJECTIVES:This study sought to analyze associations between maternal overweight and ob...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章

    doi:10.1016/j.jacc.2018.10.050

    authors: Persson M,Razaz N,Edstedt Bonamy AK,Villamor E,Cnattingius S

    更新日期:2019-01-08 00:00:00

  • Nationwide Trends of Hospital Admission and Outcomes Among Critical Limb Ischemia Patients: From 2003-2011.

    abstract:BACKGROUND:Critical limb ischemia (CLI) continues to be a major cause of vascular-related morbidity and mortality in the United States. OBJECTIVES:The study sought to characterize the trends in hospitalization of U.S. patients with CLI from 2003 to 2011, using the Nationwide Inpatient Sample. We compared the cost util...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章

    doi:10.1016/j.jacc.2016.02.040

    authors: Agarwal S,Sud K,Shishehbor MH

    更新日期:2016-04-26 00:00:00

  • The World Trade Center attack: increased frequency of defibrillator shocks for ventricular arrhythmias in patients living remotely from New York City.

    abstract:OBJECTIVES:The goal of this study was to determine whether the World Trade Center (WTC) attack on September 11, 2001, had an effect on the occurrence of ventricular arrhythmias among patients with implantable cardioverter-defibrillators (ICDs) living in Florida. BACKGROUND:Increased frequencies of ICD therapies for ve...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章

    doi:10.1016/j.jacc.2004.04.058

    authors: Shedd OL,Sears SF Jr,Harvill JL,Arshad A,Conti JB,Steinberg JS,Curtis AB

    更新日期:2004-09-15 00:00:00

  • Estimation of circumferential fiber shortening velocity by echocardiography.

    abstract::The M-mode and two-dimensional echocardiograms of 40 young patients were analyzed to compare the mean circumferential fiber shortening velocity (Vcf) of the left ventricle calculated separately by two methods. The mean circumferential fiber shortening velocity was derived from the M-mode echocardiogram as minor axis s...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章

    doi:10.1016/s0735-1097(83)80379-9

    authors: Ruschhaupt DG,Sodt PC,Hutcheon NA,Arcilla RA

    更新日期:1983-07-01 00:00:00

  • Balloon aortic valvuloplasty in adults: failure of procedure to improve long-term survival.

    abstract:OBJECTIVES:This study sought to determine the long-term outcome of adult patients undergoing percutaneous balloon aortic valvuloplasty. BACKGROUND:Percutaneous balloon aortic valvuloplasty has been offered as an alternative to aortic valve replacement for selected patients with valvular aortic stenosis. Although ballo...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章

    doi:10.1016/0735-1097(95)00363-0

    authors: Lieberman EB,Bashore TM,Hermiller JB,Wilson JS,Pieper KS,Keeler GP,Pierce CH,Kisslo KB,Harrison JK,Davidson CJ

    更新日期:1995-11-15 00:00:00

  • Erythropoietin receptor signaling mitigates renal dysfunction-associated heart failure by mechanisms unrelated to relief of anemia.

    abstract:OBJECTIVES:We examined the effect of asialoerythropoietin (asialoEPO), a nonerythrogenic derivative of erythropoietin (EPO), on renal dysfunction-associated heart failure. BACKGROUND:Although EPO is known to exert beneficial effects on cardiac function, the clinical benefits in patients with chronic kidney disease are...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章

    doi:10.1016/j.jacc.2010.04.068

    authors: Ogino A,Takemura G,Kawasaki M,Tsujimoto A,Kanamori H,Li L,Goto K,Maruyama R,Kawamura I,Takeyama T,Kawaguchi T,Watanabe T,Moriguchi Y,Saito H,Fujiwara T,Fujiwara H,Minatoguchi S

    更新日期:2010-11-30 00:00:00

  • Left ventricular echocardiographic and histologic changes: impact of chronic unloading by an implantable ventricular assist device.

    abstract:OBJECTIVES:We studied the effects of chronic left ventricular unloading by a ventricular assist device and assessed left ventricular morphologic and histologic changes. BACKGROUND:The implantable left ventricular assist device has been effective as a "bridge" to cardiac transplantation. Although there are reports docu...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章

    doi:10.1016/0735-1097(95)00555-2

    authors: Nakatani S,McCarthy PM,Kottke-Marchant K,Harasaki H,James KB,Savage RM,Thomas JD

    更新日期:1996-03-15 00:00:00

  • Ability of troponin I to predict cardiac events in patients admitted from the emergency department.

    abstract:OBJECTIVES:We sought to determine the predictive ability of troponin I (TnI) in a heterogeneous group of patients with chest pain admitted from the emergency department (ED) for exclusion of myocardial infarction (MI). BACKGROUND:Previous studies in high-risk patients demonstrated that troponin elevations are associat...

    journal_title:Journal of the American College of Cardiology

    pub_type: 评论,杂志文章

    doi:10.1016/s0735-1097(00)00943-8

    authors: Kontos MC,Anderson FP,Alimard R,Ornato JP,Tatum JL,Jesse RL

    更新日期:2000-11-15 00:00:00

  • Effects of N-acetylprocainamide on experimental atrial flutter and atrial electrophysiologic properties in conscious dogs with sterile pericarditis: comparison with the effects of quinidine.

    abstract::N-acetylprocainamide (NAPA) is said to have class III antiarrhythmic drug properties. The effects of NAPA (25 mg/kg intravenously) on sustained, stable, reentrant atrial flutter induced in 12 conscious dogs using a sterile pericarditis model were studied and compared with the effects of quinidine (5 mg/kg intravenousl...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章

    doi:10.1016/s0735-1097(87)80474-6

    authors: Okumura K,Waldo AL

    更新日期:1987-06-01 00:00:00

  • Regional left atrial stasis during atrial fibrillation and flutter: determinants and relation to stroke.

    abstract:OBJECTIVES:This study sought to 1) determine the location of left atrial stasis during atrial arrhythmia; 2) define the degree of stasis associated with significant risk of stroke; and 3) identify clinical or transthoracic echocardiographic data useful for predicting left atrial stasis. BACKGROUND:Prior studies sugges...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章

    doi:10.1016/0735-1097(96)00049-6

    authors: Shively BK,Gelgand EA,Crawford MH

    更新日期:1996-06-01 00:00:00