当前位置： SCI文献检索 > JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY期刊下所有文献 > Long-term outcome in patients with Marfan syndrome: is aortic dissection the only cause of sudden death?

Long-term outcome in patients with Marfan syndrome: is aortic dissection the only cause of sudden death?

Abstract：

OBJECTIVES:We sought to assess outcomes in a series of young patients with Marfan syndrome and to define the prevalence of ventricular arrhythmias in this patient population. BACKGROUND:While sudden death is a well-recognized outcome in Marfan syndrome, ventricular arrhythmias are not well described. METHODS:Patients were followed with echocardiography, electrocardiography, and ambulatory electrocardiography. The prevalence and associated factors for ventricular dysrhythmias were defined. RESULTS:Seventy patients with Marfan syndrome diagnosed at birth to 52 years were followed for a period of up to 24 years. All patients had cardiovascular involvement and were started on medical therapy. No patient died from aortic dissection, while 4% died from arrhythmias. Ventricular arrhythmias were present in 21% and were associated with increased left ventricular size, mitral valve prolapse, and abnormalities of repolarization. CONCLUSIONS:Cardiac complications are rare in young patients with Marfan syndrome receiving medical therapy and close clinical follow-up. Sudden death still occurs, and appears more common in patients with a dilated left ventricle. Left ventricular dilation may predispose to alterations of repolarization and fatal ventricular arrhythmias.

journal_name

J Am Coll Cardiol

journal_title

Journal of the American College of Cardiology

authors

Yetman AT,Bornemeier RA,McCrindle BW

doi

10.1016/s0735-1097(02)02699-2

subject

Has Abstract

pub_date

2003-01-15 00:00:00

pages

329-32

issue

2

eissn

0735-1097

issn

1558-3597

pii

S0735109702026992

journal_volume

41

pub_type

杂志文章

相关文献

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY文献大全
  • Impaired left atrial mechanical function after cardioversion: relation to the duration of atrial fibrillation.

    abstract：OBJECTIVES:We hypothesized that the time course of the recovery of atrial systolic function may be related to the duration of atrial fibrillation before cardioversion and sought to study noninvasively the recovery of left atrial mechanical function utilizing serial transthoracic Doppler studies. BACKGROUND:Recovery of...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/0735-1097(94)90652-1

    authors： Manning WJ,Silverman DI,Katz SE,Riley MF,Come PC,Doherty RM,Munson JT,Douglas PS

    更新日期：1994-06-01 00:00:00

  • Intravascular ultrasound molecular imaging of atheroma components in vivo.

    abstract：OBJECTIVES:Our purpose was to quantitate and confirm specific echogenic immunoliposome (ELIP) atheroma component enhancement in vivo. BACKGROUND:Targeted ELIPs for ultrasonic detection and staging of active molecular components of endothelium and atheroma have been developed. METHODS:In Yucatan miniswine, the endothe...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/j.jacc.2003.07.048

    authors： Hamilton AJ,Huang SL,Warnick D,Rabbat M,Kane B,Nagaraj A,Klegerman M,McPherson DD

    更新日期：2004-02-04 00:00:00

  • Determination of pulmonary to systemic blood flow ratio in children by a simplified Doppler echocardiographic method.

    abstract：:Doppler echocardiographic determination of the pulmonary to systemic blood flow (Qp/Qs) ratio requires calculation of pulmonary artery and aortic luminal areas and integrals of the Doppler systolic velocity curves. To simplify the Doppler calculation of the Qp/Qs ratio, the square of the ratio of pulmonary to aortic l...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/0735-1097(88)90218-5

    authors： Cloez JL,Schmidt KG,Birk E,Silverman NH

    更新日期：1988-04-01 00:00:00

  • Predictors of coronary in-stent restenosis: importance of angiotensin-converting enzyme gene polymorphism and treatment with angiotensin-converting enzyme inhibitors.

    abstract：OBJECTIVES:This study aimed to clarify the role of the angiotensin-converting enzyme (ACE) gene polymorphism in the development of in-stent restenosis. BACKGROUND:In-stent restenosis occurs after treatment of coronary artery stenosis in 12% to 32% of coronary interventions with stents. Experimental and clinical studie...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/s0735-1097(01)01580-7

    authors： Jørgensen E,Kelbaek H,Helqvist S,Jensen GV,Saunamäki K,Kastrup J,Havndrup O,Bundgaard H,Kyst Madsen J,Christiansen M,Andersen PS,Reiber JH

    更新日期：2001-11-01 00:00:00

  • Immediate effects of lung transplantation on right ventricular morphology and function in patients with variable degrees of pulmonary hypertension.

    abstract：OBJECTIVES:This study sought to determine the immediate effects of lung transplantation on right ventricular morphology and function in patients with variable degrees of pulmonary hypertension and to evaluate these features as potential markers of immediate outcome. BACKGROUND:Selected lung transplant recipients with ...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/0735-1097(95)00502-1

    authors： Katz WE,Gasior TA,Quinlan JJ,Lazar JM,Firestone L,Griffith BP,Gorcsan J 3rd

    更新日期：1996-02-01 00:00:00

  • Association between frequency of atrial and ventricular ectopic beats and biventricular pacing percentage and outcomes in patients with cardiac resynchronization therapy.

    abstract：BACKGROUND:A high percentage of biventricular pacing is required for optimal outcome in patients treated with cardiac resynchronization therapy (CRT), but the influence of ectopic beats on the success of biventricular pacing has not been well established. OBJECTIVES:This study sought to determine if increased ectopic ...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章,多中心研究,随机对照试验

    doi：10.1016/j.jacc.2014.06.1177

    authors： Ruwald MH,Mittal S,Ruwald AC,Aktas MK,Daubert JP,McNitt S,Al-Ahmad A,Jons C,Kutyifa V,Steinberg JS,Wang P,Moss AJ,Zareba W

    更新日期：2014-09-09 00:00:00

  • Significant mitral regurgitation left untreated at the time of aortic valve replacement: a comprehensive review of a frequent entity in the transcatheter aortic valve replacement era.

    abstract：:Significant mitral regurgitation (MR) is frequent in patients with severe aortic stenosis (AS). In these cases, concomitant mitral valve repair or replacement is usually performed at the time of surgical aortic valve replacement (SAVR). Transcatheter aortic valve replacement (TAVR) has recently been considered as an a...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章,评审

    doi：10.1016/j.jacc.2014.02.573

    authors： Nombela-Franco L,Ribeiro HB,Urena M,Allende R,Amat-Santos I,DeLarochellière R,Dumont E,Doyle D,DeLarochellière H,Laflamme J,Laflamme L,García E,Macaya C,Jiménez-Quevedo P,Côté M,Bergeron S,Beaudoin J,Pibarot P,Rodés-C

    更新日期：2014-06-24 00:00:00

  • Use of intraaortic balloon counterpulsation in patients presenting with cardiogenic shock: observations from the GUSTO-I Study. Global Utilization of Streptokinase and TPA for Occluded Coronary Arteries.

    abstract：OBJECTIVES:We sought to examine the use, complications and outcomes with early intraaortic balloon counterpulsation (IABP) in patients presenting with cardiogenic shock complicating acute myocardial infarction and treated with thrombolytic therapy. BACKGROUND:The use of IABP in patients with cardiogenic shock is widel...

    journal_title：Journal of the American College of Cardiology

    pub_type： 临床试验,杂志文章,多中心研究,随机对照试验

    doi：10.1016/s0735-1097(97)00227-1

    authors： Anderson RD,Ohman EM,Holmes DR Jr,Col I,Stebbins AL,Bates ER,Stomel RJ,Granger CB,Topol EJ,Califf RM

    更新日期：1997-09-01 00:00:00

  • Cardiac complications in acquired immunodeficiency syndrome (AIDS): a review.

    abstract：:Acquired immunodeficiency syndrome (AIDS) has become an increasingly important health problem worldwide. This review focuses on its cardiac complications. The key elements in the clinical syndrome are the opportunistic infections and the cancer that occur as a by-product of the immunodeficiency process. However, as ea...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章,评审

    doi：10.1016/0735-1097(89)90277-5

    authors： Acierno LJ

    更新日期：1989-04-01 00:00:00

  • Noninvasive detection of patients with ischemic and nonischemic heart disease prone to ventricular fibrillation.

    abstract：:Abnormalities in the fast Fourier transforms of signal-averaged electrocardiograms (ECGs) obtained during sinus rhythm appear to distinguish patients with ischemic heart disease and sustained monomorphic ventricular tachycardia from those without ventricular tachycardia. This study was performed to determine the power...

    journal_title：Journal of the American College of Cardiology

    pub_type： 临床试验,杂志文章

    doi：10.1016/0735-1097(90)90316-h

    authors： Lindsay BD,Ambos HD,Schechtman KB,Arthur RM,Cain ME

    更新日期：1990-12-01 00:00:00

  • Symptomatic response to antiarrhythmic drug therapy is modulated by a common single nucleotide polymorphism in atrial fibrillation.

    abstract：OBJECTIVES:This study tested the hypothesis that response to antiarrhythmic drugs (AADs) is modulated by 3 common loci associated with atrial fibrillation (AF). BACKGROUND:Recent genome-wide association studies have identified 3 loci, on chromosomes 4q25 (near PITX2), 16q22 (in ZFHX3), and 1q21 (in KCNN3), that associ...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/j.jacc.2012.01.070

    authors： Parvez B,Vaglio J,Rowan S,Muhammad R,Kucera G,Stubblefield T,Carter S,Roden D,Darbar D

    更新日期：2012-08-07 00:00:00

  • Prognostic value of serum cardiac troponin I in ambulatory patients with chronic renal failure undergoing long-term hemodialysis: a two-year outcome analysis.

    abstract：OBJECTIVES:We sought to evaluate the prognostic value of cardiac troponin I (cTnI) in asymptomatic, ambulatory patients with chronic renal failure treated with long-term hemodialysis. BACKGROUND:Smaller, short-term follow-up studies on this subject have given conflicting results. METHODS:A total of 126 ambulatory pat...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/s0735-1097(01)01513-3

    authors： Khan IA,Wattanasuwan N,Mehta NJ,Tun A,Singh N,Singh HK,Vasavada BC,Sacchi TJ

    更新日期：2001-10-01 00:00:00

  • Supplemental Vitamins and Minerals for CVD Prevention and Treatment.

    abstract：:The authors identified individual randomized controlled trials from previous meta-analyses and additional searches, and then performed meta-analyses on cardiovascular disease outcomes and all-cause mortality. The authors assessed publications from 2012, both before and including the U.S. Preventive Service Task Force ...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章,meta分析

    doi：10.1016/j.jacc.2018.04.020

    authors： Jenkins DJA,Spence JD,Giovannucci EL,Kim YI,Josse R,Vieth R,Blanco Mejia S,Viguiliouk E,Nishi S,Sahye-Pudaruth S,Paquette M,Patel D,Mitchell S,Kavanagh M,Tsirakis T,Bachiri L,Maran A,Umatheva N,McKay T,Trinidad G,

    更新日期：2018-06-05 00:00:00

  • Multislice computed tomography versus intracardiac echocardiography to evaluate the pulmonary veins before radiofrequency catheter ablation of atrial fibrillation: a head-to-head comparison.

    abstract：OBJECTIVES:The purpose of this study was to perform a head-to-head comparison between multislice computed tomography (MSCT) and intracardiac echocardiography (ICE). BACKGROUND:Different imaging techniques have been used to visualize the pulmonary veins (PV) before radiofrequency ablation of atrial fibrillation. METHO...

    journal_title：Journal of the American College of Cardiology

    pub_type： 临床试验,杂志文章

    doi：10.1016/j.jacc.2004.10.040

    authors： Jongbloed MR,Bax JJ,Lamb HJ,Dirksen MS,Zeppenfeld K,van der Wall EE,de Roos A,Schalij MJ

    更新日期：2005-02-01 00:00:00

  • Therapeutic update: non-selective beta- and alpha-adrenergic blockade in patients with coexistent chronic obstructive pulmonary disease and chronic heart failure.

    abstract：:Patients with chronic heart failure (CHF) have a resting restrictive ventilatory defect. Any type of exercise requires patients with CHF to markedly increase their minute ventilation. Patients with chronic obstructive pulmonary disease (COPD) have airflow obstruction that leads to dynamic lung hyperinflation and reduc...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章,评审

    doi：10.1016/j.jacc.2004.03.063

    authors： Sirak TE,Jelic S,Le Jemtel TH

    更新日期：2004-08-04 00:00:00

  • Beneficial effects of metoprolol in heart failure associated with coronary artery disease: a randomized trial.

    abstract：OBJECTIVES:This clinical trial was performed to determine the safety and clinical impact of titrated metoprolol therapy in patients with heart failure, documented coronary artery disease and a low ejection fraction. BACKGROUND:Despite known cardiodepressant effects, long-term use of beta-adrenergic antagonists appears...

    journal_title：Journal of the American College of Cardiology

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1016/0735-1097(94)90641-6

    authors： Fisher ML,Gottlieb SS,Plotnick GD,Greenberg NL,Patten RD,Bennett SK,Hamilton BP

    更新日期：1994-03-15 00:00:00

  • B-type natriuretic peptides improve cardiovascular disease risk prediction in a cohort of women.

    abstract：BACKGROUND:Although N-terminal pro-B-type natriuretic peptide (NT-proBNP) has a strong relationship with incident cardiovascular disease (CVD), few studies have examined whether NT-proBNP adds to risk prediction algorithms, particularly in women. OBJECTIVES:This study sought to evaluate the relationship between NT-pro...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章,多中心研究

    doi：10.1016/j.jacc.2014.04.089

    authors： Everett BM,Berger JS,Manson JE,Ridker PM,Cook NR

    更新日期：2014-10-28 00:00:00

  • Role of adenosine thallium-201 tomography for defining long-term risk in patients after acute myocardial infarction.

    abstract：OBJECTIVES:This study prospectively evaluated whether early assessment with adenosine thallium-201 tomography could better refine risk stratification on the basis of absolute extent of myocardial ischemia in postinfarction patients in clinically stable condition. BACKGROUND:Postinfarction patients are at increased ris...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/0735-1097(95)00016-W

    authors： Mahmarian JJ,Mahmarian AC,Marks GF,Pratt CM,Verani MS

    更新日期：1995-05-01 00:00:00

  • Chordal force distribution determines systolic mitral leaflet configuration and severity of functional mitral regurgitation.

    abstract：OBJECTIVES:The purpose of this study was to investigate the impact of the chordae tendineae force distribution on systolic mitral leaflet geometry and mitral valve competence in vitro. BACKGROUND:Functional mitral regurgitation is caused by changes in several elements of the valve apparatus. Interaction among these ha...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/s0735-1097(98)00627-5

    authors： Nielsen SL,Nygaard H,Fontaine AA,Hasenkam JM,He S,Andersen NT,Yoganathan AP

    更新日期：1999-03-01 00:00:00

  • Development of Quality Metrics in Ambulatory Pediatric Cardiology.

    abstract：:The American College of Cardiology Adult Congenital and Pediatric Cardiology (ACPC) Section had attempted to create quality metrics (QM) for ambulatory pediatric practice, but limited evidence made the process difficult. The ACPC sought to develop QMs for ambulatory pediatric cardiology practice. Five areas of interes...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章,评审

    doi：10.1016/j.jacc.2016.11.043

    authors： Chowdhury D,Gurvitz M,Marelli A,Anderson J,Baker-Smith C,Diab KA,Edwards TC,Hougen T,Jedeikin R,Johnson JN,Karpawich P,Lai W,Lu JC,Mitchell S,Newburger JW,Penny DJ,Portman MA,Satou G,Teitel D,Villafane J,Williams

    更新日期：2017-02-07 00:00:00

  • Cardiopulmonary Exercise Testing: What Is its Value?

    abstract：:Compared with traditional exercise tests, cardiopulmonary exercise testing (CPET) provides a thorough assessment of exercise integrative physiology involving the pulmonary, cardiovascular, muscular, and cellular oxidative systems. Due to the prognostic ability of key variables, CPET applications in cardiology have gro...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章,评审

    doi：10.1016/j.jacc.2017.08.012

    authors： Guazzi M,Bandera F,Ozemek C,Systrom D,Arena R

    更新日期：2017-09-26 00:00:00

  • Transient right but not left ventricular dysfunction after strenuous exercise at high altitude.

    abstract：OBJECTIVES:We sought to evaluate whether prolonged exercise in ultramarathon runners results in left ventricular (LV) damage. BACKGROUND:Strenuous exercise has been reported to cause LV damage. METHODS:Fourteen runners who completed an ultramarathon at high altitude underwent echocardiography, finger-tip oximetry and...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/s0735-1097(97)00179-4

    authors： Dávila-Román VG,Guest TM,Tuteur PG,Rowe WJ,Ladenson JH,Jaffe AS

    更新日期：1997-08-01 00:00:00

  • Aspirin therapy in primary cardiovascular disease prevention: a position paper of the European Society of Cardiology working group on thrombosis.

    abstract：:Although the use of oral anticoagulants (vitamin K antagonists) has been abandoned in primary cardiovascular prevention due to lack of a favorable benefit-to-risk ratio, the indications for aspirin use in this setting continue to be a source of major debate, with major international guidelines providing conflicting re...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章,评审

    doi：10.1016/j.jacc.2014.03.049

    authors： Halvorsen S,Andreotti F,ten Berg JM,Cattaneo M,Coccheri S,Marchioli R,Morais J,Verheugt FW,De Caterina R

    更新日期：2014-07-22 00:00:00

  • Risk Stratification for Patients in Cardiogenic Shock After Acute Myocardial Infarction.

    abstract：BACKGROUND:Mortality in cardiogenic shock (CS) remains high. Early risk stratification is crucial to make adequate treatment decisions. OBJECTIVES:This study sought to develop an easy-to-use, readily available risk prediction score for short-term mortality in patients with CS, derived from the IABP-SHOCK II (Intraaort...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章,随机对照试验

    doi：10.1016/j.jacc.2017.02.027

    authors： Pöss J,Köster J,Fuernau G,Eitel I,de Waha S,Ouarrak T,Lassus J,Harjola VP,Zeymer U,Thiele H,Desch S

    更新日期：2017-04-18 00:00:00

  • Long-term results after directional atherectomy of femoro-popliteal lesions.

    abstract：OBJECTIVES:Our objective in this research was the evaluation of the long-term results after directional atherectomy using the Silverhawk device (FoxHollow Technologies, Redwood City, California) of femoro-popliteal lesions. BACKGROUND:Considering reports on stent fractures in femoro-popliteal arteries, atherectomy may...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/j.jacc.2006.07.031

    authors： Zeller T,Rastan A,Sixt S,Schwarzwälder U,Schwarz T,Frank U,Bürgelin K,Müller C,Rothenpieler U,Flügel PC,Tepe G,Neumann FJ

    更新日期：2006-10-17 00:00:00

  • A randomized comparison of atrial and dual-chamber pacing in 177 consecutive patients with sick sinus syndrome: echocardiographic and clinical outcome.

    abstract：OBJECTIVES:A randomized trial was done to compare single-chamber atrial (AAI) and dual-chamber (DDD) pacing in patients with sick sinus syndrome (SSS). Primary end points were changes in left atrial (LA) size and left ventricular (LV) size and function as measured by M-mode echocardiography. BACKGROUND:In patients wit...

    journal_title：Journal of the American College of Cardiology

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1016/s0735-1097(03)00757-5

    authors： Nielsen JC,Kristensen L,Andersen HR,Mortensen PT,Pedersen OL,Pedersen AK

    更新日期：2003-08-20 00:00:00

  • Paired comparisons of efficacy of intravenous and oral procainamide in patients with inducible sustained ventricular tachyarrhythmias.

    abstract：:Thirty-eight patients who had inducible sustained ventricular tachycardia during baseline programmed electrical stimulation underwent electrophysiologic testing after both intravenous and oral administration of procainamide. Each had presented clinically with documented sustained ventricular tachycardia or out of hosp...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/0735-1097(91)90651-o

    authors： Interian A Jr,Zaman L,Velez-Robinson E,Kozlovskis P,Castellanos A,Myerburg RJ

    更新日期：1991-06-01 00:00:00

  • Sudden death in patients with implantable cardioverter defibrillators: the importance of post-shock electromechanical dissociation.

    abstract：OBJECTIVES:The purpose of this study was to determine the mechanisms of sudden death (SD) in patients with ventricular tachyarrhythmias (ventricular tachycardia/ventricular fibrillation [VT/VF]) treated with an implantable cardioverter defibrillator (ICD). BACKGROUND:Despite ICD therapy, some patients with VT/VF still...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/s0735-1097(02)01784-9

    authors： Mitchell LB,Pineda EA,Titus JL,Bartosch PM,Benditt DG

    更新日期：2002-04-17 00:00:00

  • Age-Related Characteristics and Outcomes of Patients With Heart Failure With Preserved Ejection Fraction.

    abstract：BACKGROUND:Although heart failure with preserved ejection fraction (HFpEF) is considered a disease of the elderly, younger patients are not spared from this syndrome. OBJECTIVES:This study therefore investigated the associations among age, clinical characteristics, and outcomes in patients with HFpEF. METHODS:Using d...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章,多中心研究,随机对照试验

    doi：10.1016/j.jacc.2019.05.052

    authors： Tromp J,Shen L,Jhund PS,Anand IS,Carson PE,Desai AS,Granger CB,Komajda M,McKelvie RS,Pfeffer MA,Solomon SD,Køber L,Swedberg K,Zile MR,Pitt B,Lam CSP,McMurray JJV

    更新日期：2019-08-06 00:00:00

  • Effect of aspirin on late preconditioning against myocardial stunning in conscious rabbits.

    abstract：OBJECTIVES:The goal of this study was to investigate the effect of three different doses of acetylsalicylic acid (aspirin) (ASA) on the late phase of ischemic preconditioning (PC) against myocardial stunning. BACKGROUND:Although recent evidence indicates that the late phase of ischemic PC is mediated by cyclooxygenase...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/s0735-1097(03)00086-x

    authors： Shinmura K,Kodani E,Xuan YT,Dawn B,Tang XL,Bolli R

    更新日期：2003-04-02 00:00:00