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Supplemental Vitamins and Minerals for CVD Prevention and Treatment.

Abstract：

:The authors identified individual randomized controlled trials from previous meta-analyses and additional searches, and then performed meta-analyses on cardiovascular disease outcomes and all-cause mortality. The authors assessed publications from 2012, both before and including the U.S. Preventive Service Task Force review. Their systematic reviews and meta-analyses showed generally moderate- or low-quality evidence for preventive benefits (folic acid for total cardiovascular disease, folic acid and B-vitamins for stroke), no effect (multivitamins, vitamins C, D, β-carotene, calcium, and selenium), or increased risk (antioxidant mixtures and niacin [with a statin] for all-cause mortality). Conclusive evidence for the benefit of any supplement across all dietary backgrounds (including deficiency and sufficiency) was not demonstrated; therefore, any benefits seen must be balanced against possible risks.

journal_name

J Am Coll Cardiol

journal_title

Journal of the American College of Cardiology

authors

Jenkins DJA,Spence JD,Giovannucci EL,Kim YI,Josse R,Vieth R,Blanco Mejia S,Viguiliouk E,Nishi S,Sahye-Pudaruth S,Paquette M,Patel D,Mitchell S,Kavanagh M,Tsirakis T,Bachiri L,Maran A,Umatheva N,McKay T,Trinidad G,

doi

10.1016/j.jacc.2018.04.020

subject

Has Abstract

pub_date

2018-06-05 00:00:00

pages

2570-2584

issue

22

eissn

0735-1097

issn

1558-3597

pii

S0735-1097(18)34560-1

journal_volume

71

pub_type

杂志文章,meta分析

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