Intravascular ultrasound molecular imaging of atheroma components in vivo.

abstract：OBJECTIVES:This study evaluated effects of protease-activated receptor-1 antagonist vorapaxar (Merck, Whitehouse Station, New Jersey) versus placebo among the TRACER (Thrombin Receptor Antagonist for Clinical Event Reduction in Acute Coronary Syndrome) study patients with non-ST-segment elevation acute coronary syndrom...

journal_title：Journal of the American College of Cardiology

authors： Whellan DJ,Tricoci P,Chen E,Huang Z,Leibowitz D,Vranckx P,Marhefka GD,Held C,Nicolau JC,Storey RF,Ruzyllo W,Huber K,Sinnaeve P,Weiss AT,Dery JP,Moliterno DJ,Van de Werf F,Aylward PE,White HD,Armstrong PW,Wallentin

更新日期：2014-03-25 00:00:00

abstract：OBJECTIVES:The purpose of this study was to quantify the echocardiographic abnormalities in probands who were newly diagnosed with arrhythmogenic right ventricular dysplasia (ARVD). BACKGROUND:The diagnosis of ARVD remains challenging. The Multidisciplinary Study of Right Ventricular Dysplasia was initiated to charact...

journal_title：Journal of the American College of Cardiology

authors： Yoerger DM,Marcus F,Sherrill D,Calkins H,Towbin JA,Zareba W,Picard MH,Multidisciplinary Study of Right Ventricular Dysplasia Investigators.

更新日期：2005-03-15 00:00:00

abstract：:Electrophysiologic and histologic studies were performed on Langendorff-perfused human hearts from patients who underwent heart transplantation because of extensive infarction. In nine hearts, 15 sustained ventricular tachycardias could be induced by programmed stimulation. In all hearts, mapping of epicardial and end...

journal_title：Journal of the American College of Cardiology

authors： de Bakker JM,Coronel R,Tasseron S,Wilde AA,Opthof T,Janse MJ,van Capelle FJ,Becker AE,Jambroes G

更新日期：1990-06-01 00:00:00

abstract：OBJECTIVES:We sought to compare, through a meta-analytic process, the transradial and transfemoral approaches for coronary procedures in terms of clinical and procedural outcomes. BACKGROUND:The radial approach has been increasingly used as an alternative to femoral access. Several trials have compared these two appro...

journal_title：Journal of the American College of Cardiology

authors： Agostoni P,Biondi-Zoccai GG,de Benedictis ML,Rigattieri S,Turri M,Anselmi M,Vassanelli C,Zardini P,Louvard Y,Hamon M

更新日期：2004-07-21 00:00:00

abstract：OBJECTIVES:We evaluated the short- and long-term effects of flosequinan in 47 patients with severe heart failure despite ongoing captopril treatment. BACKGROUND:There have been no previous evaluations of the long-term hemodynamic effects of any direct-acting vasodilator in patients with heart failure receiving an angi...

journal_title：Journal of the American College of Cardiology

authors： Gottlieb SS,Kukin ML,Penn J,Fisher ML,Cines M,Medina N,Yushak M,Taylor M,Packer M

更新日期：1993-10-01 00:00:00

abstract：BACKGROUND:Vascular endothelial growth factor (VEGF)-B activates cytoprotective/antiapoptotic and minimally angiogenic mechanisms via VEGF receptors. Therefore, VEGF-B might be an ideal candidate for the treatment of dilated cardiomyopathy, which displays modest microvascular rarefaction and increased rate of apoptosis...

journal_title：Journal of the American College of Cardiology

authors： Woitek F,Zentilin L,Hoffman NE,Powers JC,Ottiger I,Parikh S,Kulczycki AM,Hurst M,Ring N,Wang T,Shaikh F,Gross P,Singh H,Kolpakov MA,Linke A,Houser SR,Rizzo V,Sabri A,Madesh M,Giacca M,Recchia FA

更新日期：2015-07-14 00:00:00

abstract：BACKGROUND:There is widespread consumer concern that statin use may be associated with impaired memory and cognitive decline. OBJECTIVES:This study sought to examine the association between statin use and changes in memory and global cognition in the elderly population over 6 years and brain volumes over 2 years. Inte...

journal_title：Journal of the American College of Cardiology

authors： Samaras K,Makkar SR,Crawford JD,Kochan NA,Slavin MJ,Wen W,Trollor JN,Brodaty H,Sachdev PS

更新日期：2019-11-26 00:00:00

abstract：OBJECTIVES:The purpose of this study was to determine the efficacy and safety of enoxaparin (ENOX) versus unfractionated heparin (UFH) in patients with ST-segment elevation myocardial infarction (STEMI) receiving fibrinolytic therapy with and without clopidogrel. BACKGROUND:The efficacy and safety of ENOX and clopidog...

journal_title：Journal of the American College of Cardiology

authors： Sabatine MS,Morrow DA,Dalby A,Pfisterer M,Duris T,Lopez-Sendon J,Murphy SA,Gao R,Antman EM,Braunwald E,ExTRACT-TIMI 25 Investigators.

更新日期：2007-06-12 00:00:00

abstract：OBJECTIVES:This study sought to investigate the prevalence of potentially abnormal electrocardiographic (ECG) patterns in young individuals to assess the implications for a nationwide screening program for conditions causing sudden cardiac death (SCD). BACKGROUND:The Italian experience suggests that pre-participation ...

journal_title：Journal of the American College of Cardiology

authors： Chandra N,Bastiaenen R,Papadakis M,Panoulas VF,Ghani S,Duschl J,Foldes D,Raju H,Osborne R,Sharma S

更新日期：2014-05-20 00:00:00

abstract：OBJECTIVES:The aim of this study was to identify families affected by early repolarization syndrome (ERS) and to determine the mode of transmission of the disease. BACKGROUND:Early repolarization (ER) has recently been linked to idiopathic ventricular fibrillation. Familial inheritance of the disease has been suggeste...

journal_title：Journal of the American College of Cardiology

authors： Gourraud JB,Le Scouarnec S,Sacher F,Chatel S,Derval N,Portero V,Chavernac P,Sandoval JE,Mabo P,Redon R,Schott JJ,Le Marec H,Haïssaguerre M,Probst V

更新日期：2013-01-15 00:00:00

abstract：OBJECTIVES:This study evaluated the response to prostacyclin dose reduction in patients with primary pulmonary hypertension (PPH) who developed high cardiac outputs. BACKGROUND:Patients on prostacyclin require chronic upward dose titration to overcome tolerance to the medication. No upper limit of effective dose has b...

journal_title：Journal of the American College of Cardiology

authors： Rich S,McLaughlin VV

更新日期：1999-10-01 00:00:00

abstract：:The American College of Cardiology Adult Congenital and Pediatric Cardiology (ACPC) Section had attempted to create quality metrics (QM) for ambulatory pediatric practice, but limited evidence made the process difficult. The ACPC sought to develop QMs for ambulatory pediatric cardiology practice. Five areas of interes...

journal_title：Journal of the American College of Cardiology

authors： Chowdhury D,Gurvitz M,Marelli A,Anderson J,Baker-Smith C,Diab KA,Edwards TC,Hougen T,Jedeikin R,Johnson JN,Karpawich P,Lai W,Lu JC,Mitchell S,Newburger JW,Penny DJ,Portman MA,Satou G,Teitel D,Villafane J,Williams

更新日期：2017-02-07 00:00:00

abstract：BACKGROUND:In patients with resistant hypertension (RH) and obstructive sleep apnea (OSA), the blood pressure response to continuous positive airway pressure (CPAP) treatment is highly variable and could be associated with differential micro-ribonucleic acid (miRNA) profiles. Currently, no available methods exist to id...

journal_title：Journal of the American College of Cardiology

authors： Sánchez-de-la-Torre M,Khalyfa A,Sánchez-de-la-Torre A,Martinez-Alonso M,Martinez-García MÁ,Barceló A,Lloberes P,Campos-Rodriguez F,Capote F,Diaz-de-Atauri MJ,Somoza M,González M,Masa JF,Gozal D,Barbé F,Spanish Sleep Network

更新日期：2015-09-01 00:00:00

abstract：OBJECTIVES:This study was designed to investigate the changes in regional distensibility of the ischemic segment and of a remote nonischemic segment brought about by graded myocardial ischemia. BACKGROUND:Ventricular distensibility is a major determinant of left ventricular end-diastolic pressure. The effects of grade...

journal_title：Journal of the American College of Cardiology

authors： Marsch SC,Wanigasekera VA,Ryder WA,Wong LS,Foëx P

更新日期：1993-09-01 00:00:00

abstract：OBJECTIVES:The aim of this study was to assess the pattern of the adoption of internal mammary artery (IMA) grafting in the United States, test its association with clinical outcomes, and assess whether its effectiveness differs in key clinical subgroups. BACKGROUND:The effect of IMA grafting on major clinical outcome...

journal_title：Journal of the American College of Cardiology

authors： Hlatky MA,Boothroyd DB,Reitz BA,Shilane DA,Baker LC,Go AS

更新日期：2014-01-07 00:00:00

abstract：OBJECTIVE:The aim of this study was to evaluate the potential of paclitaxel to prevent restenosis in vivo. BACKGROUND:Paclitaxel (Taxol) is a microtubule-stabilizing compound with potent antitumor activity. It influences the cytoskeleton equilibrium by increasing the assembly of altered microtubules, thereby inducing ...

journal_title：Journal of the American College of Cardiology

authors： Herdeg C,Oberhoff M,Baumbach A,Blattner A,Axel DI,Schröder S,Heinle H,Karsch KR

更新日期：2000-06-01 00:00:00

abstract：:It has been suggested that intracardiac lymphatics may play a role in the pathophysiologic processes involving the conduction system. To test the possibility of linkage between the ventricular septum and the atrioventricular (AV) node, india ink was injected into the ventricular septum of freshly removed human hearts....

journal_title：Journal of the American College of Cardiology

authors： Uhley HN,Leeds SE,Sung MA

更新日期：1983-04-01 00:00:00

abstract：BACKGROUND:Heart transplant recipients are at high risk for mortality, with traditional risk scores performing modestly in predicting post-transplant survival, underscoring the importance of as yet unidentified factors in determining prognosis. In this analysis, the association between PM2.5 exposure levels and surviva...

journal_title：Journal of the American College of Cardiology

authors： Al-Kindi SG,Sarode A,Zullo M,Brook J,Burnett R,Oliveira GH,Huang W,Brook R,Rajagopalan S

更新日期：2019-12-17 00:00:00

abstract：BACKGROUND:Data suggest that T1 and T2 mapping have excellent diagnostic accuracy in patients with suspected myocarditis. However, the true diagnostic performance of comprehensive cardiac magnetic resonance (CMR) mapping versus endomyocardial biopsy (EMB) has not been determined. OBJECTIVES:This study assessed the per...

journal_title：Journal of the American College of Cardiology

authors： Lurz P,Luecke C,Eitel I,Föhrenbach F,Frank C,Grothoff M,de Waha S,Rommel KP,Lurz JA,Klingel K,Kandolf R,Schuler G,Thiele H,Gutberlet M

更新日期：2016-04-19 00:00:00

abstract：OBJECTIVES:The study was done to test the ability to predict the extent of angiographically determined coronary artery disease (CAD) by quantification of coronary calcium using electron-beam computed tomography (EBCT) and to compare it with more conventional parameters for delineating the angiographic extent of CAD, th...

journal_title：Journal of the American College of Cardiology

authors： Schmermund A,Denktas AE,Rumberger JA,Christian TF,Sheedy PF 2nd,Bailey KR,Schwartz RS

更新日期：1999-09-01 00:00:00

abstract：:Hemodynamic stress testing was performed in four calves with a chronically implanted left ventricular assist device consisting of a double-valved pump interposed between the left ventricular apex and the descending thoracic aorta. The device was powered either pneumatically (n = 1) or with a transcutaneous energy tran...

journal_title：Journal of the American College of Cardiology

authors： McKay RG,Penny WF,Wyman RM,Clay W,Carr JG,Bernhard WF,Grossman W

更新日期：1991-12-01 00:00:00

abstract：:Seventy adults who tested positive for human immunodeficiency virus (HIV) were prospectively studied with serial echocardiography to better define the prevalence and progression of cardiac disease in such patients. Fifty outpatients (Group A), including 44 with acquired immunodeficiency syndrome (AIDS) and 6 with AIDS...

journal_title：Journal of the American College of Cardiology

authors： Blanchard DG,Hagenhoff C,Chow LC,McCann HA,Dittrich HC

更新日期：1991-05-01 00:00:00

abstract：BACKGROUND:Recent studies reported left ventricular (LV) fibrosis in patients with primary mitral regurgitation (MR) thought to be principally due to mitral valve prolapse (MVP). OBJECTIVES:This study sought to evaluate the prevalence, characteristics, and prognostic implications of LV fibrosis in a large cohort of pr...

journal_title：Journal of the American College of Cardiology

authors： Kitkungvan D,Nabi F,Kim RJ,Bonow RO,Khan MA,Xu J,Little SH,Quinones MA,Lawrie GM,Zoghbi WA,Shah DJ

更新日期：2018-08-21 00:00:00

abstract：:Obstructive sleep apnea (OSA) is an underdiagnosed condition characterized by recurrent episodes of obstruction of the upper airway leading to sleep fragmentation and intermittent hypoxia during sleep. Obesity predisposes to OSA, and the prevalence of OSA is increasing worldwide because of the ongoing epidemic of obes...

journal_title：Journal of the American College of Cardiology

authors： Drager LF,Togeiro SM,Polotsky VY,Lorenzi-Filho G

更新日期：2013-08-13 00:00:00

abstract：OBJECTIVES:This study investigated the effect of a very long-term exercise training program is not known in chronic heart failure (CHF) patients. BACKGROUND:We previously showed that long-term moderate exercise training (ET) improves functional capacity and quality of life in New York Heart Association class II and II...

journal_title：Journal of the American College of Cardiology

authors： Belardinelli R,Georgiou D,Cianci G,Purcaro A

更新日期：2012-10-16 00:00:00

abstract：:With the emergence of new lipid risk markers and a growing cardiometabolic risk burden in the United States, there is a need to better integrate residual risk into cardiovascular disease (CVD) risk stratification. In anticipation of the Adult Treatment Panel IV (ATP IV) guidelines from the National Cholesterol Educati...

journal_title：Journal of the American College of Cardiology

authors： Ramjee V,Sperling LS,Jacobson TA

更新日期：2011-07-26 00:00:00

abstract：:This study describes the long-term outcome of 33 patients with hypertrophic cardiomyopathy who experienced a cardiac arrest but were successfully resuscitated. Cardiac arrest occurred at ages 9 to 62 years (mean 32); five patients survived multiple (two or three) arrests. A variety of treatments were administered; 18 ...

journal_title：Journal of the American College of Cardiology

authors： Cecchi F,Maron BJ,Epstein SE

更新日期：1989-05-01 00:00:00

abstract：BACKGROUND:Tricuspid regurgitation (TR) is a prevalent disease with limited treatment options. OBJECTIVES:This is the first 30-day report of the U.S. single-arm, multicenter, prospective CLASP TR early feasibility study of the PASCAL transcatheter valve repair system in the treatment of TR. METHODS:Patients with symp...

journal_title：Journal of the American College of Cardiology

authors： Kodali S,Hahn RT,Eleid MF,Kipperman R,Smith R,Lim DS,Gray WA,Narang A,Pislaru SV,Koulogiannis K,Grayburn P,Fowler D,Hawthorne K,Dahou A,Deo SH,Vandrangi P,Deuschl F,Mack MJ,Leon MB,Feldman T,Davidson CJ,CLASP TR

更新日期：2021-02-02 00:00:00

abstract：:Homocysteine is increasingly recognized as a risk factor for coronary artery disease. An understanding of its metabolism and of the importance of vitamins B6 and B12 and folate as well as enzyme levels in its regulation will aid the development of therapeutic strategies that, by lowering circulating concentrations, ma...

journal_title：Journal of the American College of Cardiology

authors： Mayer EL,Jacobsen DW,Robinson K

更新日期：1996-03-01 00:00:00

abstract：BACKGROUND:Abnormal pulmonary arterial pressure (PAP) responses to exercise have been described in select individuals; however, clinical and prognostic implications of exercise pulmonary hypertension (exPH) among broader samples remains unclear. OBJECTIVES:This study sought to investigate the association of exPH with ...

journal_title：Journal of the American College of Cardiology

authors： Ho JE,Zern EK,Lau ES,Wooster L,Bailey CS,Cunningham T,Eisman AS,Hardin KM,Farrell R,Sbarbaro JA,Schoenike MW,Houstis NE,Baggish AL,Shah RV,Nayor M,Malhotra R,Lewis GD

更新日期：2020-01-07 00:00:00