当前位置： SCI文献检索 > JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY期刊下所有文献 > Family history of severe cardiovascular disease in Marfan syndrome is associated with increased aortic diameter and decreased survival.

Family history of severe cardiovascular disease in Marfan syndrome is associated with increased aortic diameter and decreased survival.

Abstract：

OBJECTIVES:We attempted to determine whether a family history of severe cardiovascular disease in patients with the Marfan syndrome is associated with increased aortic dilation or decreased survival, or both. BACKGROUND:The prognostic importance of a family history of severe cardiovascular disease in patients with the Marfan syndrome has been incompletely examined. We hypothesized that such a family history would correlate with increased aortic dilation and would be associated with decreased survival. METHODS:One hundred eight affected patients and 48 unaffected family members from 33 multigenerational families with the Marfan syndrome underwent echocardiographic measurement of the aortic root, arch and mid-abdominal aorta. Date of birth and age at death ascertained from family pedigrees were used to perform life table analysis and estimate survival. RESULTS:Aortic root and arch diameters were significantly greater in patients with a family history of severe cardiovascular disease than in patients without such a family history. Of subjects in the highest quartile for aortic size, > 80% had such a family history in contrast to < 10% of those in the lowest quartile (chi-square 57.37, p < 0.00001). Mean age at death and cumulative probability of survival were significantly lower in patients with such a family history. CONCLUSIONS:Among patients with the Marfan syndrome, aortic dilation is greater and life expectancy shorter in those with a family history of severe cardiovascular manifestations. These data suggest that such a family history is an important risk factor for cardiovascular events in patients with the Marfan syndrome.

journal_name

J Am Coll Cardiol

journal_title

Journal of the American College of Cardiology

authors

Silverman DI,Gray J,Roman MJ,Bridges A,Burton K,Boxer M,Devereux RB,Tsipouras P

doi

10.1016/0735-1097(95)00258-0

subject

Has Abstract

pub_date

1995-10-01 00:00:00

pages

1062-7

issue

4

eissn

0735-1097

issn

1558-3597

pii

0735-1097(95)00258-0

journal_volume

26

pub_type

杂志文章

相关文献

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY文献大全
  • Repeat interventions as a long-term treatment strategy in the management of progressive coronary artery disease.

    abstract：OBJECTIVES:This study investigates whether repeat coronary interventions, applied over an extended time period, can successfully curtail the progression of ischemic symptoms and angiographic lumen narrowing. BACKGROUND:Coronary artery disease is a chronic and generally progressive disorder, and potential treatment str...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/0735-1097(96)00002-2

    authors： Lehmann KG,Maas AC,van Domburg R,de Feyter PJ,van den Brand M,Serruys PW

    更新日期：1996-05-01 00:00:00

  • Impact of Ischemic Heart Failure Etiology on Cardiac Recovery During Mechanical Unloading.

    abstract：BACKGROUND:Small-scale studies focused mainly on nonischemic cardiomyopathy (NICM) have shown that a subset of left ventricular assist device (LVAD) patients can achieve significant improvement of their native heart function, but the impact of ischemic cardiomyopathy (ICM) has not been specifically investigated. Many p...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/j.jacc.2016.07.756

    authors： Wever-Pinzon J,Selzman CH,Stoddard G,Wever-Pinzon O,Catino A,Kfoury AG,Diakos NA,Reid BB,McKellar S,Bonios M,Koliopoulou A,Budge D,Kelkhoff A,Stehlik J,Fang JC,Drakos SG

    更新日期：2016-10-18 00:00:00

  • Intermittent pacemaker dysfunction caused by digital mobile telephones.

    abstract：OBJECTIVES:This study was designed to evaluate possible interactions between digital mobile telephones and implanted pacemakers. BACKGROUND:Electromagnetic fields may interfere with normal pacemaker function. Development of bipolar sensing leads and modern noise filtering techniques have lessened this problem. However...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/0735-1097(96)00031-9

    authors： Naegeli B,Osswald S,Deola M,Burkart F

    更新日期：1996-05-01 00:00:00

  • Assessment of coronary artery bypass graft disease using cardiovascular magnetic resonance determination of flow reserve.

    abstract：OBJECTIVES:The purpose of this study was to assess the value of cardiovascular magnetic resonance (CMR)-determined graft flow and flow reserve in differentiating significant from non-significant vein graft disease. BACKGROUND:In patients after coronary artery bypass grafting (CABG), non-invasive testing may be helpful...

    journal_title：Journal of the American College of Cardiology

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1016/s0735-1097(02)02491-9

    authors： Bedaux WL,Hofman MB,Vyt SL,Bronzwaer JG,Visser CA,van Rossum AC

    更新日期：2002-11-20 00:00:00

  • Sex-Based Differences in Outcomes of Oral Anticoagulation in Patients With Atrial Fibrillation.

    abstract：BACKGROUND:Women with atrial fibrillation are at a higher risk of stroke, despite treatment with warfarin. It is unclear if women treated with direct oral anticoagulants (DOACs) have better clinical outcomes, especially when considering the quality of anticoagulation control of warfarin. OBJECTIVES:This study compared...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/j.jacc.2018.04.066

    authors： Law SWY,Lau WCY,Wong ICK,Lip GYH,Mok MT,Siu CW,Chan EW

    更新日期：2018-07-17 00:00:00

  • Eplerenone and atrial fibrillation in mild systolic heart failure: results from the EMPHASIS-HF (Eplerenone in Mild Patients Hospitalization And SurvIval Study in Heart Failure) study.

    abstract：OBJECTIVES:The purpose of this study was to analyze the incidence of new atrial fibrillation or flutter (AFF) in the EMPHASIS-HF (Eplerenone in Mild Patients Hospitalization And SurvIval Study in Heart Failure) database. BACKGROUND:Aldosterone antagonism in heart failure might influence atrial fibrosis and remodeling ...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章,多中心研究,随机对照试验

    doi：10.1016/j.jacc.2011.11.063

    authors： Swedberg K,Zannad F,McMurray JJ,Krum H,van Veldhuisen DJ,Shi H,Vincent J,Pitt B,EMPHASIS-HF Study Investigators.

    更新日期：2012-05-01 00:00:00

  • Sudden death and the competitive athlete: perspectives on preparticipation screening studies.

    abstract：:Sudden death in healthy athletes is uncommon but, when it occurs, the primary mechanism is cardiovascular. The major cause of sudden death in the young athlete is hypertrophic cardiomyopathy or related conditions characterized by left ventricular hypertrophy, aortic rupture due to cystic medial necrosis and congenital...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章,评审

    doi：10.1016/s0735-1097(86)80285-6

    authors： Epstein SE,Maron BJ

    更新日期：1986-01-01 00:00:00

  • Failure of calcium channel blockers to improve ventricular relaxation in humans.

    abstract：OBJECTIVES:The objective of this study was to ascertain whether the reversal of low peak filling rates after administration of calcium channel blockers in patients with diastolic dysfunction indicates true improvement in the rate of ventricular relaxation and left ventricular end-diastolic pressure measured by invasive...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/0735-1097(93)90735-j

    authors： Nishimura RA,Schwartz RS,Holmes DR Jr,Tajik AJ

    更新日期：1993-01-01 00:00:00

  • N-terminal pro-B-type natriuretic peptide-guided, intensive patient management in addition to multidisciplinary care in chronic heart failure a 3-arm, prospective, randomized pilot study.

    abstract：OBJECTIVES:This study was designed to investigate whether the addition of N-terminal pro-B-type natriuretic peptide-guided, intensive patient management (BM) to multidisciplinary care (MC) improves outcome in patients following hospitalization due to heart failure (HF). BACKGROUND:Patients hospitalized due to HF exper...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章,多中心研究,随机对照试验

    doi：10.1016/j.jacc.2009.08.078

    authors： Berger R,Moertl D,Peter S,Ahmadi R,Huelsmann M,Yamuti S,Wagner B,Pacher R

    更新日期：2010-02-16 00:00:00

  • Variability of individual platelet reactivity over time in patients treated with clopidogrel: insights from the ELEVATE-TIMI 56 trial.

    abstract：BACKGROUND:The degree of antiplatelet response to clopidogrel has been associated with clinical outcomes. Studies have investigated whether adjustment of antiplatelet therapies based on a single platelet function test is beneficial. OBJECTIVES:The aim of the study was to test the stability of platelet reactivity measu...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章,多中心研究,随机对照试验

    doi：10.1016/j.jacc.2014.03.051

    authors： Hochholzer W,Ruff CT,Mesa RA,Mattimore JF,Cyr JF,Lei L,Frelinger AL 3rd,Michelson AD,Berg DD,Angiolillo DJ,O'Donoghue ML,Sabatine MS,Mega JL

    更新日期：2014-07-29 00:00:00

  • Electrical catheter ablation in the left and right ventricular wall in dogs: relation between delivered energy and histopathologic changes.

    abstract：:Electrical catheter ablation of arrhythmogenic sites is now being used for the treatment of ventricular tachycardias. However, the extent and type of the ablation lesion in relation to energy level are controversial and not well known. In 10 beagles, single cathodal shocks of 30 (4 dogs), 80 (2 dogs) or 250 J (4 dogs)...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/s0735-1097(86)80194-2

    authors： Hauer RN,Straks W,Borst C,Robles de Medina EO

    更新日期：1986-09-01 00:00:00

  • Prognostic significance of transient ischemic episodes: response to treatment shows improved prognosis. Results of the Total Ischemic Burden Bisoprolol Study (TIBBs) follow-up.

    abstract：OBJECTIVES:The Total Ischemic Burden Bisoprolol Study (TIBBS) follow-up examined cardiac event rates in relation to transient ischemia and its treatment. BACKGROUND:It is unclear whether transient ischemia on the ambulatory electrocardiogram has prognostic implications in stable angina and whether medical treatment ca...

    journal_title：Journal of the American College of Cardiology

    pub_type： 临床试验,杂志文章,多中心研究,随机对照试验

    doi：10.1016/0735-1097(96)00122-2

    authors： Von Arnim T

    更新日期：1996-07-01 00:00:00

  • Carotid artery stenting in acute stroke.

    abstract：OBJECTIVES:The purpose of this study is to demonstrate the technical success of carotid artery stenting in acute extracranial internal carotid artery (ICA) occlusion as well as the benefit in clinical outcome. BACKGROUND:Stroke caused by acute occlusion of the ICA is associated with a significant level of morbidity an...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/j.jacc.2011.08.044

    authors： Papanagiotou P,Roth C,Walter S,Behnke S,Grunwald IQ,Viera J,Politi M,Körner H,Kostopoulos P,Haass A,Fassbender K,Reith W

    更新日期：2011-11-29 00:00:00

  • Elevated intra-abdominal pressure in acute decompensated heart failure: a potential contributor to worsening renal function?

    abstract：OBJECTIVES:This study sought to determine whether changes in intra-abdominal pressure (IAP) with aggressive diuretic or vasodilator therapy are associated with improvement in renal function in acute decompensated heart failure (ADHF). BACKGROUND:Elevated IAP (>or=8 mm Hg) is associated with intra-abdominal organ dysfu...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/j.jacc.2007.09.043

    authors： Mullens W,Abrahams Z,Skouri HN,Francis GS,Taylor DO,Starling RC,Paganini E,Tang WH

    更新日期：2008-01-22 00:00:00

  • Family-Based Approaches to Cardiovascular Health Promotion.

    abstract：:Cardiovascular disease is the leading cause of mortality in the world, and the increasing burden is largely a consequence of modifiable behavioral risk factors that interact with genomics and the environment. Continuous cardiovascular health promotion and disease prevention throughout the lifespan is critical, and the...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章,评审

    doi：10.1016/j.jacc.2016.01.036

    authors： Vedanthan R,Bansilal S,Soto AV,Kovacic JC,Latina J,Jaslow R,Santana M,Gorga E,Kasarskis A,Hajjar R,Schadt EE,Björkegren JL,Fayad ZA,Fuster V

    更新日期：2016-04-12 00:00:00

  • High prevalence of atrial fibrosis in patients with dilated cardiomyopathy.

    abstract：OBJECTIVES:We examined the extent of fibrotic changes in the left atrium of cardiomyopathic human hearts and investigated the relation of mechanical overload caused by left ventricular dysfunction to fibrosis of the left atrium. BACKGROUND:Left atrial dysfunction in dilated cardiomyopathy may contribute to progression...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/0735-1097(94)00529-y

    authors： Ohtani K,Yutani C,Nagata S,Koretsune Y,Hori M,Kamada T

    更新日期：1995-04-01 00:00:00

  • Pre-clinical diastolic dysfunction.

    abstract：:Pre-clinical diastolic dysfunction (PDD) has been broadly defined as left ventricular diastolic dysfunction without the diagnosis of congestive heart failure (HF) and with normal systolic function. PDD is an entity that remains poorly understood, yet has definite clinical significance. Although few original studies ha...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章,评审

    doi：10.1016/j.jacc.2013.10.063

    authors： Wan SH,Vogel MW,Chen HH

    更新日期：2014-02-11 00:00:00

  • Use of cardiopulmonary exercise testing with hemodynamic monitoring in the prognostic assessment of ambulatory patients with chronic heart failure.

    abstract：OBJECTIVES:We studied whether direct assessment of the hemodynamic response to exercise could improve the prognostic evaluation of patients with heart failure (HF) and identify those in whom the main cause of the reduced functional capacity is related to extracardiac factors. BACKGROUND:Peak exercise oxygen consumptio...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/s0735-1097(98)00672-x

    authors： Metra M,Faggiano P,D'Aloia A,Nodari S,Gualeni A,Raccagni D,Dei Cas L

    更新日期：1999-03-15 00:00:00

  • Perioperative morbidity and mortality after transmyocardial laser revascularization: incidence and risk factors for adverse events.

    abstract：OBJECTIVES:The purpose of this study was to describe the incidence and spectrum of perioperative cardiac and noncardiac morbidity and mortality after transmyocardial laser revascularization (TMR) and to identify predictors of these adverse clinical events. BACKGROUND:Clinical studies have demonstrated the efficacy of ...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/s0735-1097(98)00676-7

    authors： Hughes GC,Landolfo KP,Lowe JE,Coleman RB,Donovan CL

    更新日期：1999-03-15 00:00:00

  • Immediate effects of lung transplantation on right ventricular morphology and function in patients with variable degrees of pulmonary hypertension.

    abstract：OBJECTIVES:This study sought to determine the immediate effects of lung transplantation on right ventricular morphology and function in patients with variable degrees of pulmonary hypertension and to evaluate these features as potential markers of immediate outcome. BACKGROUND:Selected lung transplant recipients with ...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/0735-1097(95)00502-1

    authors： Katz WE,Gasior TA,Quinlan JJ,Lazar JM,Firestone L,Griffith BP,Gorcsan J 3rd

    更新日期：1996-02-01 00:00:00

  • Left ventricular outflow tract to left atrial communication secondary to rupture of mitral-aortic intervalvular fibrosa in infective endocarditis: diagnosis by transesophageal echocardiography and color flow imaging.

    abstract：:Infection of the mitral-aortic intervalvular fibrosa occurs most commonly in association with infective endocarditis of the aortic valve. Infection of the aortic valve results in a regurgitant jet that presumably strikes this subaortic interannular zone of fibrous tissue and produces a secondary site of infection. Inf...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/s0735-1097(10)80082-8

    authors： Bansal RC,Graham BM,Jutzy KR,Shakudo M,Shah PM

    更新日期：1990-02-01 00:00:00

  • The association of alcohol consumption and incident heart failure: the Cardiovascular Health Study.

    abstract：OBJECTIVES:We investigated the association between alcohol consumption and incident congestive heart failure (CHF) both overall and after adjusting for incident myocardial infarction (MI). BACKGROUND:Moderate alcohol consumption has been associated with lower risk of CHF and MI. METHODS:The Cardiovascular Health stud...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/j.jacc.2006.02.066

    authors： Bryson CL,Mukamal KJ,Mittleman MA,Fried LP,Hirsch CH,Kitzman DW,Siscovick DS

    更新日期：2006-07-18 00:00:00

  • Reversibility of cardiac abnormalities in human immunodeficiency virus (HIV)-infected individuals: a serial echocardiographic study.

    abstract：:Seventy adults who tested positive for human immunodeficiency virus (HIV) were prospectively studied with serial echocardiography to better define the prevalence and progression of cardiac disease in such patients. Fifty outpatients (Group A), including 44 with acquired immunodeficiency syndrome (AIDS) and 6 with AIDS...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/s0735-1097(10)80134-2

    authors： Blanchard DG,Hagenhoff C,Chow LC,McCann HA,Dittrich HC

    更新日期：1991-05-01 00:00:00

  • Does the rest electrocardiogram after myocardial infarction determine the predictive value of exercise-induced ST depression? A 2 year follow-up study in a veteran population.

    abstract：:The failure of exercise-induced ST segment depression to consistently predict prognosis in patients after myocardial infarction could be a result of population differences and the rest electrocardiogram (ECG). These hypotheses were tested by studying 198 veterans who survived a myocardial infarction, underwent a subma...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/0735-1097(89)90178-2

    authors： Klein J,Froelicher VF,Detrano R,Dubach P,Yen R

    更新日期：1989-08-01 00:00:00

  • Electrophysiologic effects of d-sotalol in humans.

    abstract：:Sotalol is a beta-adrenergic blocking agent that prolongs the duration of the cardiac action potential in humans, without affecting the upstroke velocity of depolarization. The dextrorotatory isomer, d-sotalol, retains these class III effects, but has little beta-blocking activity in vitro. d-Sotalol has not been stud...

    journal_title：Journal of the American College of Cardiology

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1016/s0735-1097(87)80182-1

    authors： McComb JM,McGovern B,McGowan JB,Ruskin JN,Garan H

    更新日期：1987-07-01 00:00:00

  • Inhibition of mitochondrial permeability transition prevents sepsis-induced myocardial dysfunction and mortality.

    abstract：OBJECTIVES:The purpose of this study was to test whether mitochondrial dysfunction is causative of sepsis sequelae, a mouse model of peritonitis sepsis induced by cecal ligation and perforation. Inhibition of mitochondrial permeability transition was achieved by means of pharmacological drugs and overexpression of the ...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/j.jacc.2006.02.069

    authors： Larche J,Lancel S,Hassoun SM,Favory R,Decoster B,Marchetti P,Chopin C,Neviere R

    更新日期：2006-07-18 00:00:00

  • Chordal force distribution determines systolic mitral leaflet configuration and severity of functional mitral regurgitation.

    abstract：OBJECTIVES:The purpose of this study was to investigate the impact of the chordae tendineae force distribution on systolic mitral leaflet geometry and mitral valve competence in vitro. BACKGROUND:Functional mitral regurgitation is caused by changes in several elements of the valve apparatus. Interaction among these ha...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/s0735-1097(98)00627-5

    authors： Nielsen SL,Nygaard H,Fontaine AA,Hasenkam JM,He S,Andersen NT,Yoganathan AP

    更新日期：1999-03-01 00:00:00

  • Renal artery stent placement: utility in lesions difficult to treat with balloon angioplasty.

    abstract：OBJECTIVES:We assessed the safety and efficacy of stent placement in patients with poorly controlled hypertension and renal artery stenoses, which are difficult to treat with balloon angioplasty alone. BACKGROUND:Preliminary experience with stent placement suggests improved results over balloon angioplasty alone in pa...

    journal_title：Journal of the American College of Cardiology

    pub_type： 临床试验,杂志文章

    doi：10.1016/s0735-1097(97)00348-3

    authors： White CJ,Ramee SR,Collins TJ,Jenkins JS,Escobar A,Shaw D

    更新日期：1997-11-15 00:00:00

  • Determinants of the spontaneous ectopic activity in repetitive monomorphic idiopathic ventricular tachycardia.

    abstract：:Twenty-four hour ambulatory electrocardiographic tape recordings of 30 patients (16 men and 14 women, mean age 42 +/- 17 years) with repetitive monomorphic idiopathic ventricular tachycardia were analyzed using a new computerized system designed to study 15 RR cycles and mean heart rate of the 3 minutes preceding any ...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/s0735-1097(86)80139-5

    authors： Zimmermann M,Maisonblanche P,Cauchemez B,Leclercq JF,Coumel P

    更新日期：1986-06-01 00:00:00

  • Level of Blood Pressure Control and Cardiovascular Events: SPRINT Criteria Versus the 2014 Hypertension Recommendations.

    abstract：BACKGROUND:Blood pressure (BP) targets from the SPRINT (Systolic Blood Pressure Intervention Trial) differ from targets of the 2014 hypertension (HTN) recommendations of the Eighth Joint National Committee. OBJECTIVES:The goal of this study was to estimate the proportion of hypertensive adults with who would meet BP g...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/j.jacc.2016.03.572

    authors： Ko MJ,Jo AJ,Park CM,Kim HJ,Kim YJ,Park DW

    更新日期：2016-06-21 00:00:00