Does the rest electrocardiogram after myocardial infarction determine the predictive value of exercise-induced ST depression? A 2 year follow-up study in a veteran population.

Abstract:

:The failure of exercise-induced ST segment depression to consistently predict prognosis in patients after myocardial infarction could be a result of population differences and the rest electrocardiogram (ECG). These hypotheses were tested by studying 198 veterans who survived a myocardial infarction, underwent a submaximal predischarge treadmill exercise test and were followed up for cardiac events for 2 years. During the 2 years, 29 deaths, 19 reinfarctions and 28 revascularization procedures were documented. The prevalence of death or reinfarction was two times higher in patients who had exercise-induced ST depression than in patients who did not. However, in the 55 patients without Q waves, the risk increased to 11 times for an abnormal ST response. These findings suggest that exercise-induced ST depression only predicts high risk in patients after myocardial infarction whose ECG at rest does not exhibit Q waves and that differences in the prevalence of rest ECG patterns are the most likely explanation for the failure of agreement among prior studies.

journal_name

J Am Coll Cardiol

authors

Klein J,Froelicher VF,Detrano R,Dubach P,Yen R

doi

10.1016/0735-1097(89)90178-2

subject

Has Abstract

pub_date

1989-08-01 00:00:00

pages

305-11

issue

2

eissn

0735-1097

issn

1558-3597

pii

0735-1097(89)90178-2

journal_volume

14

pub_type

杂志文章
  • Atheroma morphology and distribution in proximal left anterior descending coronary artery: in vivo observations.

    abstract:OBJECTIVES:This study sought to examine, in vivo, the shape and position of atheroma in the proximal left anterior descending coronary artery. BACKGROUND:The prevalence, shape and location of atheromas involving the proximal left anterior descending artery have implications regarding the role of disturbed shear forces...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章

    doi:10.1016/0735-1097(95)00551-x

    authors: Kimura BJ,Russo RJ,Bhargava V,McDaniel MB,Peterson KL,DeMaria AN

    更新日期:1996-03-15 00:00:00

  • Selective elimination of retrograde conduction by intraoperative neodymium: YAG laser photocoagulation in dogs.

    abstract:OBJECTIVES:The purpose of this study was to test the feasibility of selective elimination of ventriculoatrial (VA) conduction by limited laser photocoagulation of the atrioventricular (AV) node, and to analyze the histologic substrate of unidirectional retrograde block. BACKGROUND:Atrioventricular node reentry require...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章

    doi:10.1016/0735-1097(93)90698-z

    authors: Littmann L,Svenson RH,Bharati S,Lev M,Chuang CH,Kempler P,Splinter R,Tuntelder JR,Tatsis GP

    更新日期:1993-02-01 00:00:00

  • High dose titration of calcium channel blocking agents for primary pulmonary hypertension: guidelines for short-term drug testing.

    abstract::Forty-seven patients with primary pulmonary hypertension were evaluated with a dose titration protocol utilizing nifedipine (20 mg orally) or diltiazem (60 mg orally) given every hour until maximal effectiveness was achieved. Of the patients tested, 15 (32%) had a greater than 20% reduction in pulmonary artery pressur...

    journal_title:Journal of the American College of Cardiology

    pub_type: 指南,杂志文章

    doi:10.1016/0735-1097(91)90556-o

    authors: Rich S,Kaufmann E

    更新日期:1991-11-01 00:00:00

  • Short-term effects of early intravenous treatment with a beta-adrenergic blocking agent or a specific bradycardiac agent in patients with acute myocardial infarction receiving thrombolytic therapy.

    abstract:OBJECTIVES:This study was conducted to explore mechanisms that could explain the possible clinical benefit of early administration of a beta 1-selective adrenoreceptor blocking agent or a bradycardiac drug as adjunct to thrombolysis in acute myocardial infarction. BACKGROUND:The effects of beta-blockers given concomit...

    journal_title:Journal of the American College of Cardiology

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.1016/0735-1097(93)90044-2

    authors: Van de Werf F,Janssens L,Brzostek T,Mortelmans L,Wackers FJ,Willems GM,Heidbüchel H,Lesaffre E,Scheys I,Collen D

    更新日期:1993-08-01 00:00:00

  • Adoption and effectiveness of internal mammary artery grafting in coronary artery bypass surgery among Medicare beneficiaries.

    abstract:OBJECTIVES:The aim of this study was to assess the pattern of the adoption of internal mammary artery (IMA) grafting in the United States, test its association with clinical outcomes, and assess whether its effectiveness differs in key clinical subgroups. BACKGROUND:The effect of IMA grafting on major clinical outcome...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章,多中心研究

    doi:10.1016/j.jacc.2013.08.1632

    authors: Hlatky MA,Boothroyd DB,Reitz BA,Shilane DA,Baker LC,Go AS

    更新日期:2014-01-07 00:00:00

  • Cardioprotective medication is associated with improved survival in patients with peripheral arterial disease.

    abstract:OBJECTIVES:We sought to investigate the effect of cardiac medication on long-term mortality in patients with peripheral arterial disease (PAD). BACKGROUND:Peripheral arterial disease is associated with increased cardiovascular morbidity and mortality. Treatment guidelines recommend aggressive management of risk factor...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章

    doi:10.1016/j.jacc.2005.09.074

    authors: Feringa HH,van Waning VH,Bax JJ,Elhendy A,Boersma E,Schouten O,Galal W,Vidakovic RV,Tangelder MJ,Poldermans D

    更新日期:2006-03-21 00:00:00

  • Transesophageal echocardiography and carotid ultrasound in patients with cerebral ischemia: prevalence of findings and recurrent stroke risk.

    abstract:OBJECTIVES:This study was conducted to determine the yield of transesophageal echocardiographic findings in a consecutive series of patients with stroke and transient ischemic attack, with and without carotid stenosis, and to estimate the recurrent stroke risk associated with specific echocardiographic findings. BACKG...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章

    doi:10.1016/0735-1097(94)90662-9

    authors: Comess KA,DeRook FA,Beach KW,Lytle NJ,Golby AJ,Albers GW

    更新日期:1994-06-01 00:00:00

  • Prolongation of isovolumetric relaxation time as assessed by Doppler echocardiography predicts doxorubicin-induced systolic dysfunction in humans.

    abstract::A reasonably sensitive and specific noninvasive test for doxorubicin cardiotoxicity is needed. In addition, few data exist on the short- and long-term effects of doxorubicin on diastolic filling. To determine if pulsed Doppler indexes of diastolic filling could predict doxorubicin-induced systolic dysfunction, 26 pati...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章

    doi:10.1016/0735-1097(92)90138-d

    authors: Stoddard MF,Seeger J,Liddell NE,Hadley TJ,Sullivan DM,Kupersmith J

    更新日期:1992-07-01 00:00:00

  • Predictors of congestive heart failure in the elderly: the Cardiovascular Health Study.

    abstract:OBJECTIVES:We sought to characterize the predictors of incident congestive heart failure (CHF), as determined by central adjudication, in a community-based elderly population. BACKGROUND:The elderly constitute a growing proportion of patients admitted to the hospital with CHF, and CHF is a leading source of morbidity ...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章

    doi:10.1016/s0735-1097(00)00582-9

    authors: Gottdiener JS,Arnold AM,Aurigemma GP,Polak JF,Tracy RP,Kitzman DW,Gardin JM,Rutledge JE,Boineau RC

    更新日期:2000-05-01 00:00:00

  • Heart rate variability in patients with ventricular arrhythmias: effect of antiarrhythmic drugs. Antiarrhythmic Drug Evaluation Group (ADEG).

    abstract::The purpose of this study was to investigate whether heart rate variability could be reliably assessed in patients with ventricular arrhythmias and to evaluate whether it is affected by antiarrhythmic drugs. The study was based on an analysis of 239 ambulatory electrocardiographic (ECG) recordings obtained from 67 pat...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章

    doi:10.1016/s0735-1097(10)80172-x

    authors: Zuanetti G,Latini R,Neilson JM,Schwartz PJ,Ewing DJ

    更新日期:1991-03-01 00:00:00

  • Complications of inappropriate use of spironolactone in heart failure: when an old medicine spirals out of new guidelines.

    abstract:OBJECTIVES:This study was designed to investigate the appropriateness and complications of the use of spironolactone for heart failure (HF) in clinical practice. BACKGROUND:Spironolactone was reported by one prospective randomized trial to decrease morbidity and mortality in patients with New York Heart Association (N...

    journal_title:Journal of the American College of Cardiology

    pub_type: 临床试验,评论,杂志文章,随机对照试验

    doi:10.1016/s0735-1097(02)02694-3

    authors: Bozkurt B,Agoston I,Knowlton AA

    更新日期:2003-01-15 00:00:00

  • Prognostic value of myocardial infarct size and contractile reserve using magnetic resonance imaging.

    abstract:OBJECTIVES:Our aim was to assess the predictive value of myocardial infarct size assessed with late gadolinium-enhanced (LGE) magnetic resonance imaging (MRI) in medically treated patients with chronic myocardial infarction relative to contractile reserve on low-dose dobutamine magnetic resonance (DSMR) for long-term e...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章,多中心研究

    doi:10.1016/j.jacc.2009.07.027

    authors: Kelle S,Roes SD,Klein C,Kokocinski T,de Roos A,Fleck E,Bax JJ,Nagel E

    更新日期:2009-11-03 00:00:00

  • Noninvasive doppler echocardiographic evaluation of left ventricular filling pressures in patients with cardiomyopathies: a simultaneous Doppler echocardiographic and cardiac catheterization study.

    abstract:OBJECTIVES:The purpose of this study was to examine the relation of the mitral flow velocity curves to left ventricular filling pressures in patients with two different types of myocardial problems: hypertrophic cardiomyopathy and severe left ventricular systolic dysfunction. BACKGROUND:Previous studies have suggested...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章

    doi:10.1016/S0735-1097(96)00315-4

    authors: Nishimura RA,Appleton CP,Redfield MM,Ilstrup DM,Holmes DR Jr,Tajik AJ

    更新日期:1996-11-01 00:00:00

  • Restrictive right ventricular physiology: its presence and symptomatic contribution in patients with pulmonary valvular stenosis.

    abstract:OBJECTIVES:The aim of this study was to examine whether restrictive right ventricular (RV) physiology (the presence of antegrade pulmonary arterial flow in late diastole) occurred in patients with moderate to severe isolated pulmonary valvular stenosis (PVS) and to estimate its prevalence and relationship to RV functio...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章

    doi:10.1016/j.jacc.2007.06.042

    authors: Lam YY,Kaya MG,Goktekin O,Gatzoulis MA,Li W,Henein MY

    更新日期:2007-10-09 00:00:00

  • Hypertrophic cardiomyopathy: role of the implantable cardioverter-defibrillator.

    abstract:OBJECTIVES:We report the occurrence of cardiac events during long-term follow-up in patients with hypertrophic cardiomyopathy (HCM) after cardioverter-defibrillator implantation. BACKGROUND:The identification of patients at high risk for sudden death and the prevention of recurrence of sudden death in HCM represents a...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章

    doi:10.1016/s0735-1097(98)00037-0

    authors: Primo J,Geelen P,Brugada J,Filho AL,Mont L,Wellens F,Valentino M,Brugada P

    更新日期:1998-04-01 00:00:00

  • Intermittent claudication: an objective office-based assessment.

    abstract:OBJECTIVES:We sought to compare standard lower extremity vascular laboratory treadmill exercise with the office-based active pedal plantarflexion technique. BACKGROUND:Intermittent claudication is relatively common in elderly patients and is an important predictor of cardiovascular morbidity and mortality. Noninvasive...

    journal_title:Journal of the American College of Cardiology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/s0735-1097(01)01120-2

    authors: McPhail IR,Spittell PC,Weston SA,Bailey KR

    更新日期:2001-04-01 00:00:00

  • Hydrochlorothiazide is superior to isradipine for reduction of left ventricular mass: results of a multicenter trial. The Isradipine Study Group.

    abstract:OBJECTIVES:We sought to determine the efficacy of isradipine in reducing left ventricular (LV) mass and wall thickness in hypertensive patients. BACKGROUND:LV hypertrophy on the echocardiogram is a strong predictor of cardiovascular events. Reduction of LV mass may be a desirable goal of drug therapy for hypertension....

    journal_title:Journal of the American College of Cardiology

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.1016/s0735-1097(97)00311-2

    authors: Papademetriou V,Gottdiener JS,Narayan P,Cushman WG,Zachariah PK,Gottdiener PS,Chase GA

    更新日期:1997-12-01 00:00:00

  • Left atrial appendage function and thrombus formation in atrial fibrillation-flutter: a transesophageal echocardiographic study.

    abstract:OBJECTIVES:The purpose of this study was to investigate left atrial appendage size, function and thrombus prevalence in patients with atrial "fibrillation-flutter." BACKGROUND:Thrombus formation and peripheral embolization in atrial fibrillation are related to left atrial appendage dysfunction. Embolization occurs les...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章

    doi:10.1016/0735-1097(94)90557-6

    authors: Santiago D,Warshofsky M,Li Mandri G,Di Tullio M,Coromilas J,Reiffel J,Homma S

    更新日期:1994-07-01 00:00:00

  • Hemodynamic evaluation of a chronically implanted, electrically powered left ventricular assist system: responses to acute circulatory stress.

    abstract::Hemodynamic stress testing was performed in four calves with a chronically implanted left ventricular assist device consisting of a double-valved pump interposed between the left ventricular apex and the descending thoracic aorta. The device was powered either pneumatically (n = 1) or with a transcutaneous energy tran...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章

    doi:10.1016/0735-1097(91)90521-a

    authors: McKay RG,Penny WF,Wyman RM,Clay W,Carr JG,Bernhard WF,Grossman W

    更新日期:1991-12-01 00:00:00

  • Double outlet right ventricle associated with common atrioventricular canal: report of nine anatomic specimens.

    abstract::Double outlet right ventricle associated with complete atrioventricular (AV) canal is a rare malformation. Nine cases are reported. In this abnormality the anterior AV leaflet is undivided and free floating and the aortic and pulmonary orifices are in the same frontal plane. In four of the nine cases, the conus was bi...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章

    doi:10.1016/s0735-1097(86)80057-2

    authors: Toussaint M,Planche C,Graff WC,Royon M,Ribierre M

    更新日期:1986-08-01 00:00:00

  • Gender differences in molecular remodeling in pressure overload hypertrophy.

    abstract:OBJECTIVES:The objective of this study was to examine gender differences in left ventricular (LV) function and expression of cardiac genes in response to LV pressure overload due to ascending aortic stenosis in rats. BACKGROUND:Clinical studies have documented gender differences in the pattern of adaptive LV hypertrop...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章

    doi:10.1016/s0735-1097(99)00165-5

    authors: Weinberg EO,Thienelt CD,Katz SE,Bartunek J,Tajima M,Rohrbach S,Douglas PS,Lorell BH

    更新日期:1999-07-01 00:00:00

  • Myocardial flow reserve in long-term survivors of repair of anomalous left coronary artery from pulmonary artery.

    abstract:OBJECTIVES:This study sought to evaluate regional myocardial flow reserve in long-term survivors of repair of anomalous left coronary artery from pulmonary artery (ALCAPA) and to relate the flow abnormalities to the patients' exercise performance. BACKGROUND:Patients with ALCAPA usually present during infancy with sev...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章

    doi:10.1016/s0735-1097(97)00488-9

    authors: Singh TP,Di Carli MF,Sullivan NM,Leonen MF,Morrow WR

    更新日期:1998-02-01 00:00:00

  • Atherectomy of the subclavian artery for patients with symptomatic coronary-subclavian steal syndrome.

    abstract:OBJECTIVES:This study addresses the efficacy of directional atherectomy in the subclavian artery for the relief of angina in patients with the coronary-subclavian steal syndrome. In addition, we review the histologic findings from the atherectomy specimens. BACKGROUND:The coronary-subclavian steal syndrome may occur a...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章

    doi:10.1016/0735-1097(93)90369-c

    authors: Breall JA,Grossman W,Stillman IE,Gianturco LE,Kim D

    更新日期:1993-06-01 00:00:00

  • Clinical and angiographic comparison of matched patients with successful directional coronary atherectomy or stent implantation for primary coronary artery lesions.

    abstract:OBJECTIVES:This study was designed to compare the long-term clinical and angiographic effects of successful directional atherectomy and stent implantation and to examine whether restenosis is related to the mechanism of lumen improvement as well as the extent of lumen gain. BACKGROUND:Directional atherectomy and coron...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章

    doi:10.1016/0735-1097(96)00229-x

    authors: Umans VA,Melkert R,Foley DP,Serruys PW

    更新日期:1996-09-01 00:00:00

  • Rapid change in plaque size, composition, and molecular footprint after recombinant apolipoprotein A-I Milano (ETC-216) administration: magnetic resonance imaging study in an experimental model of atherosclerosis.

    abstract:OBJECTIVES:This study sought to assess the effect of short-term apolipoprotein (apo) A-I(Milano) administration on plaque size and on suspected markers of plaque vulnerability. BACKGROUND:Long-term lipid-lowering interventions can regress and stabilize atherosclerotic plaques. However, the majority of recurrent events...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章

    doi:10.1016/j.jacc.2007.09.071

    authors: Ibanez B,Vilahur G,Cimmino G,Speidl WS,Pinero A,Choi BG,Zafar MU,Santos-Gallego CG,Krause B,Badimon L,Fuster V,Badimon JJ

    更新日期:2008-03-18 00:00:00

  • Coronary angioplasty in young adults: initial results and late outcome.

    abstract::The initial and late outcome of coronary angioplasty was studied in 148 patients less than 40 years of age (mean 36.4 +/- 3). Angioplasty was performed on a single vessel in 70% of patients and on multiple vessels in 30%; it was performed on a totally occluded vessel in 20%. Angioplasty was successful in 90.5% of pati...

    journal_title:Journal of the American College of Cardiology

    pub_type: 临床试验,杂志文章

    doi:10.1016/0735-1097(90)90302-6

    authors: Webb JG,Myler RK,Shaw RE,Anwar A,Stertzer SH

    更新日期:1990-12-01 00:00:00

  • Pathophysiology and prognostic significance of Holter-detected ST segment depression after myocardial infarction. The Tissue Plasminogen Activator: Toronto (TPAT) Study Group.

    abstract:OBJECTIVES:We performed Holter monitoring on days 4 and 7 after acute myocardial infarction in 109 patients to assess whether ST segment shift would identify those with more severe coronary artery disease, left ventricular dysfunction and unfavorable prognosis. BACKGROUND:Silent myocardial ischemia is a frequent and p...

    journal_title:Journal of the American College of Cardiology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/0735-1097(92)90242-f

    authors: Langer A,Minkowitz J,Dorian P,Casella L,Harris L,Morgan CD,Armstrong PW

    更新日期:1992-11-15 00:00:00

  • Silent left ventricular dysfunction during routine activity after thrombolytic therapy for acute myocardial infarction.

    abstract::To investigate prospectively the occurrence and significance of postinfarction transient left ventricular dysfunction, 33 ambulatory patients who underwent thrombolytic therapy after myocardial infarction were monitored continuously for 187 +/- 56 min during normal activity with a radionuclide left ventricular functio...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章

    doi:10.1016/0735-1097(90)92817-l

    authors: Kayden DS,Wackers FJ,Zaret BL

    更新日期:1990-06-01 00:00:00

  • Do associations with C-reactive protein and extent of coronary artery disease account for the increased cardiovascular risk of renal insufficiency?

    abstract:OBJECTIVES:We sought to determine whether the association of higher C-reactive protein levels (CRP) and more extensive coronary artery disease (CAD) explains the high cardiovascular risk of renal insufficiency (RI). BACKGROUND:Renal insufficiency and renal failure (RF) have been associated with increased cardiovascula...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章

    doi:10.1016/s0735-1097(03)00564-3

    authors: Zebrack JS,Anderson JL,Beddhu S,Horne BD,Bair TL,Cheung A,Muhlestein JB,Intermountain Heart Collaborative Study Group.

    更新日期:2003-07-02 00:00:00

  • Selective dopamine-1 agonist therapy in severe hypertension: effects of intravenous fenoldopam.

    abstract::To determine the effects of dopamine-1 agonist therapy in severe hypertension, blood pressure, heart rate, catecholamines and left ventricular function were studied in 18 patients (10 with renal disease) with diastolic blood pressure greater than 120 mm Hg (range 124 to 160) after intravenous fenoldopam therapy. Const...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章

    doi:10.1016/s0735-1097(98)90073-0

    authors: White WB,Radford MJ,Gonzalez FM,Weed SG,McCabe EJ,Katz AM

    更新日期:1988-05-01 00:00:00