当前位置： SCI文献检索 > JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY期刊下所有文献 > Hemodynamic evaluation of a chronically implanted, electrically powered left ventricular assist system: responses to acute circulatory stress.

Hemodynamic evaluation of a chronically implanted, electrically powered left ventricular assist system: responses to acute circulatory stress.

Abstract：

:Hemodynamic stress testing was performed in four calves with a chronically implanted left ventricular assist device consisting of a double-valved pump interposed between the left ventricular apex and the descending thoracic aorta. The device was powered either pneumatically (n = 1) or with a transcutaneous energy transmission system (n = 3). Hemodynamic evaluation (cardiac output and right and left ventricular and pulmonary and carotid artery pressures) was carried out at baseline and during all hemodynamically stressed states. Atrial pacing and ventricular pacing to a heart rate of 140 beats/min resulted in no significant change in right or left heart filling pressures or cardiac output. Preload reduction with nitroprusside or transient inferior vena cava balloon occlusion resulted in a marked decrease in left ventricular pressure with preservation of mean arterial pressure. Phenylephrine administration resulted in a marked rise in mean arterial pressure with no change in cardiac output or filling pressure. Induction of ventricular fibrillation resulted in a decrease of mean left ventricular pressure to 11 +/- 8 mm Hg, but mean arterial pressure was maintained at greater than or equal to 50 mm Hg. It is concluded that a multicomponent, implantable, electrically powered assist system is capable of maintaining a normal cardiac output under a wide range of loading conditions and chronotropic states. Although this device is clearly preload dependent, it is capable of maintaining normal systemic pressures during conditions of severe left ventricular dysfunction and circulatory collapse.

journal_name

J Am Coll Cardiol

journal_title

Journal of the American College of Cardiology

authors

McKay RG,Penny WF,Wyman RM,Clay W,Carr JG,Bernhard WF,Grossman W

doi

10.1016/0735-1097(91)90521-a

subject

Has Abstract

pub_date

1991-12-01 00:00:00

pages

1779-86

issue

7

eissn

0735-1097

issn

1558-3597

pii

0735-1097(91)90521-A

journal_volume

18

pub_type

杂志文章

相关文献

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY文献大全
  • Incorporating Coronary Calcification Into Pre-Test Assessment of the Likelihood of Coronary Artery Disease.

    abstract：BACKGROUND:The prevalence of obstructive coronary artery disease (CAD) in symptomatic patients referred for diagnostic testing has declined, warranting optimization of individualized diagnostic strategies. OBJECTIVES:This study sought to present a simple, clinically applicable tool enabling estimation of the likelihoo...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/j.jacc.2020.09.585

    authors： Winther S,Schmidt SE,Mayrhofer T,Bøtker HE,Hoffmann U,Douglas PS,Wijns W,Bax J,Nissen L,Lynggaard V,Christiansen JJ,Saraste A,Bøttcher M,Knuuti J

    更新日期：2020-11-24 00:00:00

  • Attenuation of interatrial conduction using right atrial septal catheter ablation.

    abstract：OBJECTIVES:We sought to characterize a method of attenuating interatrial conduction using radiofrequency ablated lesions applied to the right atrial septum. BACKGROUND:Interatrial conduction occurs in specific zones. Recent data suggest that interatrial conduction can be important in triggering and sustaining atrial f...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/s0735-1097(01)01466-8

    authors： Schwartzman D,Warman EN,Devine WA,Mehra R

    更新日期：2001-09-01 00:00:00

  • Long-Term Use of Cardiovascular Drugs: Challenges for Research and for Patient Care.

    abstract：:Little is known about the benefits and risks of the long-term use of cardiovascular drugs. Evidence from randomized clinical trials (RCTs) rarely goes beyond a few years of follow-up, but patients are often given continuous treatment with multiple drugs well into old age. We focus on 4 commonly used cardiovascular dru...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章,评审

    doi：10.1016/j.jacc.2015.07.018

    authors： Rossello X,Pocock SJ,Julian DG

    更新日期：2015-09-15 00:00:00

  • Rapid change in plaque size, composition, and molecular footprint after recombinant apolipoprotein A-I Milano (ETC-216) administration: magnetic resonance imaging study in an experimental model of atherosclerosis.

    abstract：OBJECTIVES:This study sought to assess the effect of short-term apolipoprotein (apo) A-I(Milano) administration on plaque size and on suspected markers of plaque vulnerability. BACKGROUND:Long-term lipid-lowering interventions can regress and stabilize atherosclerotic plaques. However, the majority of recurrent events...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/j.jacc.2007.09.071

    authors： Ibanez B,Vilahur G,Cimmino G,Speidl WS,Pinero A,Choi BG,Zafar MU,Santos-Gallego CG,Krause B,Badimon L,Fuster V,Badimon JJ

    更新日期：2008-03-18 00:00:00

  • Late na(+) current inhibition by ranolazine reduces torsades de pointes in the chronic atrioventricular block dog model.

    abstract：OBJECTIVES:This study investigated whether ranolazine reduces dofetilide-induced torsades de pointes (TdP) in a model of long QT syndrome with down-regulated K(+) currents due to hypertrophic remodeling in the dog with chronic atrioventricular block (cAVB). BACKGROUND:Ranolazine inhibits the late Na(+) current (I(NaL)...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/j.jacc.2009.10.033

    authors： Antoons G,Oros A,Beekman JD,Engelen MA,Houtman MJ,Belardinelli L,Stengl M,Vos MA

    更新日期：2010-02-23 00:00:00

  • High-intensity signals in carotid plaques on T1-weighted magnetic resonance imaging predict coronary events in patients with coronary artery disease.

    abstract：OBJECTIVES:The purpose of this study was to determine whether high-intensity carotid plaques visualized by a noncontrast T1-weighted imaging technique, magnetization-prepared rapid acquisition with gradient echo (MPRAGE), predict future coronary events in patients with clinically stable coronary artery disease (CAD). ...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/j.jacc.2011.01.056

    authors： Noguchi T,Yamada N,Higashi M,Goto Y,Naito H

    更新日期：2011-07-19 00:00:00

  • Cardiac Implantable Electronic Devices in Patients With Left Ventricular Assist Systems.

    abstract：:Recent progress and evolution in device engineering, surgical implantation practices, and periprocedural management have advanced the promise of durable support with left ventricular assist systems (LVAS) in patients with stage D heart failure. With greater uptake of LVAS globally, a growing population of LVAS recipie...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章,评审

    doi：10.1016/j.jacc.2018.01.061

    authors： Berg DD,Vaduganathan M,Upadhyay GA,Singh JP,Mehra MR,Stewart GC

    更新日期：2018-04-03 00:00:00

  • Complications of inappropriate use of spironolactone in heart failure: when an old medicine spirals out of new guidelines.

    abstract：OBJECTIVES:This study was designed to investigate the appropriateness and complications of the use of spironolactone for heart failure (HF) in clinical practice. BACKGROUND:Spironolactone was reported by one prospective randomized trial to decrease morbidity and mortality in patients with New York Heart Association (N...

    journal_title：Journal of the American College of Cardiology

    pub_type： 临床试验,评论,杂志文章,随机对照试验

    doi：10.1016/s0735-1097(02)02694-3

    authors： Bozkurt B,Agoston I,Knowlton AA

    更新日期：2003-01-15 00:00:00

  • Myocardial redox state predicts in-hospital clinical outcome after cardiac surgery effects of short-term pre-operative statin treatment.

    abstract：OBJECTIVES:The purpose of this study was to evaluate the role of the myocardial redox state in the development of in-hospital complications after cardiac surgery and the effect of statins on the myocardial redox state. BACKGROUND:Statins improve clinical outcome after cardiac surgery, but it is unclear whether they ex...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章,随机对照试验

    doi：10.1016/j.jacc.2011.08.062

    authors： Antoniades C,Demosthenous M,Reilly S,Margaritis M,Zhang MH,Antonopoulos A,Marinou K,Nahar K,Jayaram R,Tousoulis D,Bakogiannis C,Sayeed R,Triantafyllou C,Koumallos N,Psarros C,Miliou A,Stefanadis C,Channon KM,Casadei B

    更新日期：2012-01-03 00:00:00

  • Response of human coronary arteries to acetylcholine after injury by coronary angioplasty.

    abstract：OBJECTIVES:The aim of this study was to investigate the effect of intracoronary administration of acetylcholine on large epicardial vessels 8 days after successful coronary angioplasty. BACKGROUND:Intracoronary infusion of acetylcholine causes vessel dilation in patients without angiographic evidence of coronary ather...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/0735-1097(93)90239-w

    authors： el-Tamimi H,Davies GJ,Crea F,Maseri A

    更新日期：1993-04-01 00:00:00

  • Platelet glycoprotein IIb/IIIa receptor blockade and coronary resistance in unstable angina.

    abstract：OBJECTIVES:We designed a study to explore the effect of glycoprotein (GP) IIb/IIIa blockade on the atherosclerotic plaque and distal coronary vasculature. BACKGROUND:Platelet GP IIb/IIIa blockers have been proven to be beneficial in acute ischemic syndromes. This effect has also been attributed to the prevention of mi...

    journal_title：Journal of the American College of Cardiology

    pub_type： 临床试验,杂志文章

    doi：10.1016/s0735-1097(02)02590-1

    authors： Marzilli M,Sambuceti G,Testa R,Fedele S

    更新日期：2002-12-18 00:00:00

  • Simulation of acute myopericarditis by constrictive pericardial disease with endomyocardial fibrosis due to methysergide therapy.

    abstract：:Methysergide ( Sansert ) has been associated with numerous fibrotic disorders. In particular, multiple cardiac lesions have been described in cases where methysergide was thought to have played a causative role. A patient is described who presented with cardiac findings suggestive of acute myopericarditis . An inflamm...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/s0735-1097(84)80342-3

    authors： Harbin AD,Gerson MC,O'Connell JB

    更新日期：1984-07-01 00:00:00

  • Balloon valvotomy for critical stenosis or atresia of pulmonary valve in newborns.

    abstract：OBJECTIVES:Percutaneous balloon valvotomy was studied retrospectively in newborns with critical pulmonary valve stenosis or atresia to assess its potential role as an alternative therapy to operation. BACKGROUND:Severe right ventricular outflow tract obstructions are life-threatening conditions requiring prostaglandin...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/0735-1097(95)00369-X

    authors： Gournay V,Piéchaud JF,Delogu A,Sidi D,Kachaner J

    更新日期：1995-12-01 00:00:00

  • Importance of ablating all potential right atrial flutter circuits in postcardiac surgery patients.

    abstract：OBJECTIVES:In patients with atrial flutter (AFL) and postoperative right atrial incisional scars, we sought to assess if the use of additional ablative lesions that targeted all potential re-entrant circuits, regardless of the presenting type of flutter, would prevent long-term recurrence. BACKGROUND:Patients with AFL...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/j.jacc.2004.04.045

    authors： Verma A,Marrouche NF,Seshadri N,Schweikert RA,Bhargava M,Burkhardt JD,Kilicaslan F,Cummings J,Saliba W,Natale A

    更新日期：2004-07-21 00:00:00

  • Influence of age and gender on the presence of coronary calcium detected by ultrafast computed tomography.

    abstract：OBJECTIVES:This study sought to determine the relation between coronary calcification detected with ultrafast computed tomography and lumen narrowing defined with angiography and evaluated whether this relation is influenced by age and gender. BACKGROUND:Ultrafast computed tomography has been shown to be a sensitive m...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/0735-1097(94)00342-n

    authors： Devries S,Wolfkiel C,Fusman B,Bakdash H,Ahmed A,Levy P,Chomka E,Kondos G,Zajac E,Rich S

    更新日期：1995-01-01 00:00:00

  • Validation of a digital color Doppler flow measurement method for pulmonary regurgitant volumes and regurgitant fractions in an in vitro model and in a chronic animal model of postoperative repaired tetralogy of Fallot.

    abstract：OBJECTIVES:The purpose of this study was to validate a digital color Doppler (DCD) automated cardiac flow measurement method for quantifying pulmonary regurgitation (PR) in an in vitro and a chronic animal model of the right ventricular outflow tract of postoperative tetralogy of Fallot (TOF). BACKGROUND:There has bee...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/s0735-1097(00)01106-2

    authors： Mori Y,Irvine T,Jones M,Rusk RA,Pham Q,Kenny A,Sahn DJ

    更新日期：2001-02-01 00:00:00

  • Comparison of three Doppler ultrasound methods in the prediction of pulmonary artery pressure.

    abstract：:Pulmonary artery pressure was noninvasively estimated by three Doppler echocardiographic methods in 50 consecutive patients undergoing cardiac catheterization. First, a systolic transtricuspid gradient was calculated from Doppler-detected tricuspid regurgitation; clinical jugular venous pressure or a fixed value of 14...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/s0735-1097(87)80047-5

    authors： Chan KL,Currie PJ,Seward JB,Hagler DJ,Mair DD,Tajik AJ

    更新日期：1987-03-01 00:00:00

  • Differential effects of dobutamine and a phosphodiesterase inhibitor on early diastolic filling in patients with congestive heart failure.

    abstract：OBJECTIVES:This study was designed to compare the influence of beta-adrenergic stimulation (dobutamine) and a selective phosphodiesterase inhibitor (MS-857) on left ventricular diastolic performance and Doppler transmitral flow velocity patterns in patients with congestive heart failure and to elucidate the mechanisms ...

    journal_title：Journal of the American College of Cardiology

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1016/0735-1097(94)00369-2

    authors： Nagata K,Iwase M,Sobue T,Yokota M

    更新日期：1995-02-01 00:00:00

  • Appearance of abnormal Q waves early in the course of acute myocardial infarction: implications for efficacy of thrombolytic therapy.

    abstract：OBJECTIVES:The purpose of this study was to determine the time course of the appearance of abnormal Q waves on the electrocardiogram (ECG) over the first 6 h of symptoms of myocardial infarction and to determine what implications, if any, such Q waves have for the efficacy of thrombolytic therapy. BACKGROUND:Severe my...

    journal_title：Journal of the American College of Cardiology

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1016/0735-1097(94)00514-q

    authors： Raitt MH,Maynard C,Wagner GS,Cerqueira MD,Selvester RH,Weaver WD

    更新日期：1995-04-01 00:00:00

  • Endo-epicardial homogenization of the scar versus limited substrate ablation for the treatment of electrical storms in patients with ischemic cardiomyopathy.

    abstract：OBJECTIVES:This study investigated the impact on recurrences of 2 different substrate approaches for the treatment of these arrhythmias. BACKGROUND:Catheter ablation of electrical storms (ES) for ventricular arrhythmias (VAs) has shown moderate long-term efficacy in patients with ischemic cardiomyopathy. METHODS:Nine...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/j.jacc.2012.03.044

    authors： Di Biase L,Santangeli P,Burkhardt DJ,Bai R,Mohanty P,Carbucicchio C,Dello Russo A,Casella M,Mohanty S,Pump A,Hongo R,Beheiry S,Pelargonio G,Santarelli P,Zucchetti M,Horton R,Sanchez JE,Elayi CS,Lakkireddy D,Tondo C

    更新日期：2012-07-10 00:00:00

  • Quantification of tricuspid regurgitation by measuring the width of the vena contracta with Doppler color flow imaging: a clinical study.

    abstract：OBJECTIVE:We sought to evaluate the vena contracta width (VCW) measured using color Doppler as an index of severity of tricuspid regurgitation (TR). BACKGROUND:The VCW is a reliable measure of mitral and aortic regurgitation, but its value in measuring TR is uncertain. METHODS:In 71 consecutive patients with TR, the ...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/s0735-1097(00)00762-2

    authors： Tribouilloy CM,Enriquez-Sarano M,Bailey KR,Tajik AJ,Seward JB

    更新日期：2000-08-01 00:00:00

  • Myocardial Infarction Produces Sustained Proinflammatory Endothelial Activation in Remote Arteries.

    abstract：BACKGROUND:In the months after acute myocardial infarction (MI), risk for acute atherothrombotic events in nonculprit arteries increases several fold. OBJECTIVES:This study investigated whether sustained proinflammatory and prothrombotic endothelial alterations occur in remote vessels after MI. METHODS:Wild-type mice...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/j.jacc.2018.06.044

    authors： Moccetti F,Brown E,Xie A,Packwood W,Qi Y,Ruggeri Z,Shentu W,Chen J,López JA,Lindner JR

    更新日期：2018-08-28 00:00:00

  • Angiotensin II inhibits the forearm vascular response to increased arterial pressure in humans.

    abstract：OBJECTIVES:This study tested the hypothesis that angiotensin II may inhibit the forearm vascular resistance response to an increase in arterial pressure in normal humans. BACKGROUND:Angiotensin II inhibits baroreflex-mediated reductions in heart rate and peripheral sympathetic activity during increases in arterial pre...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/0735-1097(95)96225-n

    authors： Goldsmith SR,Hasking GJ

    更新日期：1995-01-01 00:00:00

  • Predictors of defibrillation efficacy in patients undergoing epicardial defibrillator implantation. The Multicenter Pacemaker-Cardioverter-Defibrillator (PCD) Investigators Group.

    abstract：OBJECTIVES:The objective of this study was to identify predictors of defibrillation threshold in patients undergoing epicardial defibrillator implantation. BACKGROUND:Factors that predict epicardial defibrillation efficacy are poorly defined. METHODS:The data from 375 consecutive adult patients were reviewed. After e...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章,多中心研究

    doi：10.1016/0735-1097(93)90379-f

    authors： Leitch JW,Yee R

    更新日期：1993-06-01 00:00:00

  • Long-term quality of life after ablation of atrial fibrillation the impact of recurrence, symptom relief, and placebo effect.

    abstract：OBJECTIVES:We sought to determine the relationship between atrial fibrillation (AF) ablation efficacy, quality of life (QoL), and AF-specific symptoms at 2 years. BACKGROUND:Although the primary goal of AF ablation is QoL improvement, this effect has yet to be demonstrated in the long term. METHODS:A total of 502 sym...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/j.jacc.2010.01.040

    authors： Wokhlu A,Monahan KH,Hodge DO,Asirvatham SJ,Friedman PA,Munger TM,Bradley DJ,Bluhm CM,Haroldson JM,Packer DL

    更新日期：2010-05-25 00:00:00

  • Threshold of Pulmonary Hypertension Associated With Increased Mortality.

    abstract：BACKGROUND:There is increasing evidence that current thresholds for diagnosing pulmonary hypertension (PHT) underestimate the prognostic impact of PHT. OBJECTIVES:The aim of this study was to determine the prognostic impact of increasing pulmonary pressures within the National Echocardiography Database of Australia co...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/j.jacc.2019.03.482

    authors： Strange G,Stewart S,Celermajer DS,Prior D,Scalia GM,Marwick TH,Gabbay E,Ilton M,Joseph M,Codde J,Playford D,NEDA Contributing Sites.

    更新日期：2019-06-04 00:00:00

  • Clopidogrel responsiveness regardless of the discontinuation date predicts increased blood loss and transfusion requirement after off-pump coronary artery bypass graft surgery.

    abstract：OBJECTIVES:the purpose of this study was to evaluate the association of the percentage of platelet inhibitory response to clopidogrel as assessed by modified thromboelastography with bleeding and transfusion requirement after off-pump coronary artery bypass graft (OPCABG) surgery. BACKGROUND:Interindividual variabilit...

    journal_title：Journal of the American College of Cardiology

    pub_type： 临床试验,杂志文章

    doi：10.1016/j.jacc.2010.03.108

    authors： Kwak YL,Kim JC,Choi YS,Yoo KJ,Song Y,Shim JK

    更新日期：2010-12-07 00:00:00

  • Fibrosis, Connexin-43, and Conduction Abnormalities in the Brugada Syndrome.

    abstract：BACKGROUND:The right ventricular outflow tract (RVOT) is acknowledged to be responsible for arrhythmogenesis in Brugada syndrome (BrS), but the pathophysiology remains controversial. OBJECTIVES:This study assessed the substrate underlying BrS at post-mortem and in vivo, and the role for open thoracotomy ablation. MET...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/j.jacc.2015.08.862

    authors： Nademanee K,Raju H,de Noronha SV,Papadakis M,Robinson L,Rothery S,Makita N,Kowase S,Boonmee N,Vitayakritsirikul V,Ratanarapee S,Sharma S,van der Wal AC,Christiansen M,Tan HL,Wilde AA,Nogami A,Sheppard MN,Veerakul G,

    更新日期：2015-11-03 00:00:00

  • Metallothionein suppresses angiotensin II-induced nicotinamide adenine dinucleotide phosphate oxidase activation, nitrosative stress, apoptosis, and pathological remodeling in the diabetic heart.

    abstract：OBJECTIVES:We evaluated metallothionein (MT)-mediated cardioprotection from angiotensin II (Ang II)-induced pathologic remodeling with and without underlying diabetes. BACKGROUND:Cardiac-specific metallothionein-overexpressing transgenic (MT-TG) mice are resistant to diabetic cardiomyopathy largely because of the anti...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/j.jacc.2008.05.019

    authors： Zhou G,Li X,Hein DW,Xiang X,Marshall JP,Prabhu SD,Cai L

    更新日期：2008-08-19 00:00:00

  • Temporal trends and geographic variation of lower-extremity amputation in patients with peripheral artery disease: results from U.S. Medicare 2000-2008.

    abstract：OBJECTIVES:This study sought to characterize temporal trends, patient-specific factors, and geographic variation associated with amputation in patients with lower-extremity peripheral artery disease (LE PAD) during the study period. BACKGROUND:Amputation represents the end-stage failure for those with LE PAD, and litt...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章,多中心研究

    doi：10.1016/j.jacc.2012.08.983

    authors： Jones WS,Patel MR,Dai D,Subherwal S,Stafford J,Calhoun S,Peterson ED

    更新日期：2012-11-20 00:00:00