当前位置： SCI文献检索 > JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY期刊下所有文献 > Endo-epicardial homogenization of the scar versus limited substrate ablation for the treatment of electrical storms in patients with ischemic cardiomyopathy.

Endo-epicardial homogenization of the scar versus limited substrate ablation for the treatment of electrical storms in patients with ischemic cardiomyopathy.

Abstract：

OBJECTIVES:This study investigated the impact on recurrences of 2 different substrate approaches for the treatment of these arrhythmias. BACKGROUND:Catheter ablation of electrical storms (ES) for ventricular arrhythmias (VAs) has shown moderate long-term efficacy in patients with ischemic cardiomyopathy. METHODS:Ninety-two consecutive patients (81% male, age 62 ± 13 years) with ischemic cardiomyopathy and ES underwent catheter ablation. Patients were treated either by confining the radiofrequency lesions to the endocardial surface with limited substrate ablation (Group 1, n = 49) or underwent endocardial and epicardial ablation of abnormal potentials within the scar (homogenization of the scar, Group 2, n = 43). Epicardial access was obtained in all Group 2 patients, whereas epicardial ablation was performed in 33% (14) of these patients. RESULTS:Mean ejection fraction was 27 ± 5. During a mean follow-up of 25 ± 10 months, the VAs recurrence rate of any ventricular tachycardia (VTs) was 47% (23 of 49 patients) in Group 1 and 19% (8 of 43 patients) in Group 2 (log-rank p = 0.006). One patient in Group 1 and 1 patient in Group 2 died at follow-up for noncardiac reasons. CONCLUSIONS:Our study demonstrates that ablation using endo-epicardial homogenization of the scar significantly increases freedom from VAs in ischemic cardiomyopathy patients.

journal_name

J Am Coll Cardiol

journal_title

Journal of the American College of Cardiology

authors

Di Biase L,Santangeli P,Burkhardt DJ,Bai R,Mohanty P,Carbucicchio C,Dello Russo A,Casella M,Mohanty S,Pump A,Hongo R,Beheiry S,Pelargonio G,Santarelli P,Zucchetti M,Horton R,Sanchez JE,Elayi CS,Lakkireddy D,Tondo C

doi

10.1016/j.jacc.2012.03.044

subject

Has Abstract

pub_date

2012-07-10 00:00:00

pages

132-41

issue

2

eissn

0735-1097

issn

1558-3597

pii

S0735-1097(12)01421-0

journal_volume

60

pub_type

杂志文章

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