Determinants of the spontaneous ectopic activity in repetitive monomorphic idiopathic ventricular tachycardia.

Abstract:

:Twenty-four hour ambulatory electrocardiographic tape recordings of 30 patients (16 men and 14 women, mean age 42 +/- 17 years) with repetitive monomorphic idiopathic ventricular tachycardia were analyzed using a new computerized system designed to study 15 RR cycles and mean heart rate of the 3 minutes preceding any defined event. The mean (+/- SD) number of events analyzed per patient in 24 hours was 610 +/- 483 for single premature ventricular complexes, 622 +/- 490 for couplets, 260 +/- 411 for runs of 3 complexes, 186 +/- 476 for runs of 4, 108 +/- 173 for runs of 5, 82 +/- 129 for runs of 6 to 10 and 83 +/- 116 for runs of more than 10 complexes. The heart rate was faster before runs of ventricular tachycardia than before isolated extrasystoles (p less than 0.01) and a positive linear correlation was observed between the mean preceding heart rate and the type of extrasystolic activity, the length of the runs increasing with increasing preceding heart rate (r = 0.98, p less than 0.001). A long RR interval just before the occurrence of runs was present in 77% of the cases (23 of 30) with or without an oscillatory pattern of RR intervals due to bigeminy or trigeminy, and the length of the runs correlated positively with the duration of this long preceding diastole (r = 0.90, p less than 0.05).(ABSTRACT TRUNCATED AT 250 WORDS)

journal_name

J Am Coll Cardiol

authors

Zimmermann M,Maisonblanche P,Cauchemez B,Leclercq JF,Coumel P

doi

10.1016/s0735-1097(86)80139-5

subject

Has Abstract

pub_date

1986-06-01 00:00:00

pages

1219-27

issue

6

eissn

0735-1097

issn

1558-3597

pii

S0735-1097(86)80139-5

journal_volume

7

pub_type

杂志文章
  • Left ventricular diastolic function in infants, children, and adolescents. Reference values and analysis of morphologic and physiologic determinants of echocardiographic Doppler flow signals during growth and maturation.

    abstract:OBJECTIVES:The aim of this study was to set up reference values for Doppler flow-derived left ventricular filling parameters and to evaluate physiologic determinants of changes in signal expression related to maturation. BACKGROUND:In left ventricular diastolic function studies, age-related modulations in signal expre...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章

    doi:10.1016/s0735-1097(98)00379-9

    authors: Schmitz L,Koch H,Bein G,Brockmeier K

    更新日期:1998-11-01 00:00:00

  • Anisoylated plasminogen streptokinase activator complex in acute myocardial infarction: a placebo-controlled arteriographic coronary recanalization study.

    abstract::Anisoylated plasminogen streptokinase activator complex (APSAC) is a new thrombolytic agent that is of interest because of its ease of administration as an intravenous bolus injection. This report describes the first double-blind, placebo-controlled evaluation of intravenous APSAC for coronary recanalization in acute ...

    journal_title:Journal of the American College of Cardiology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/s0735-1097(87)80181-x

    authors: Timmis AD,Griffin B,Crick JC,Sowton E

    更新日期:1987-07-01 00:00:00

  • The origins of the sinus node pacemaker complex in man: demonstration of dominant and subsidiary foci.

    abstract::To test the hypothesis that the human sinus node is capable of demonstrating multiple sites of impulse generation, we assessed spontaneous shifts in the sinus node pacemaker complex, and shifts after overdrive atrial pacing, premature atrial stimulation and carotid sinus massage. A total of 24 patients aged 59 +/- 15 ...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章

    doi:10.1016/s0735-1097(87)80081-5

    authors: Gomes JA,Winters SL

    更新日期:1987-01-01 00:00:00

  • Cardiac tamponade and pericardial effusion: respiratory variation in transvalvular flow velocities studied by Doppler echocardiography.

    abstract::Cardiac tamponade has been associated with an abnormally increased respiratory variation in transvalvular blood flow velocities. To determine whether this finding is consistently present in cardiac tamponade, seven patients were studied prospectively with Doppler echocardiography before and after pericardiocentesis an...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章,评审

    doi:10.1016/s0735-1097(98)90060-2

    authors: Appleton CP,Hatle LK,Popp RL

    更新日期:1988-05-01 00:00:00

  • Lysis of plasminogen activator-resistant platelet-rich coronary artery thrombus with combined bolus injection of recombinant tissue-type plasminogen activator and antiplatelet GPIIb/IIIa antibody.

    abstract::Resistance of coronary occlusive thrombus to thrombolytic therapy, found in some patients with acute myocardial infarction, may be due to the presence of platelet-rich coronary clot. Reperfusion therapy in such patients may require the development and evaluation of alternative strategies in animal models. Therefore, p...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章

    doi:10.1016/0735-1097(90)90327-l

    authors: Yasuda T,Gold HK,Leinbach RC,Saito T,Guerrero JL,Jang IK,Holt R,Fallon JT,Collen D

    更新日期:1990-12-01 00:00:00

  • Influence of contemporary versus 30-year blood pressure levels on left ventricular mass and geometry: the Framingham Heart Study.

    abstract::To determine whether long-term blood pressure levels correlate with left ventricular mass, echocardiographic measurements were performed in 152 men and 299 women who were participants in the Framingham Heart Study. All subjects were free of obesity and cardiovascular and pulmonary disease, were not taking antihyperten...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章

    doi:10.1016/0735-1097(91)90549-o

    authors: Lauer MS,Anderson KM,Levy D

    更新日期:1991-11-01 00:00:00

  • Oral anticoagulation and antiplatelets in atrial fibrillation patients after myocardial infarction and coronary intervention.

    abstract:OBJECTIVES:The purpose of this study was to investigate the risk of thrombosis and bleeding according to multiple antithrombotic treatment regimens in atrial fibrillation (AF) patients after myocardial infarction (MI) or percutaneous coronary intervention (PCI). BACKGROUND:The optimal antithrombotic treatment strategy...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章

    doi:10.1016/j.jacc.2013.05.029

    authors: Lamberts M,Gislason GH,Olesen JB,Kristensen SL,Schjerning Olsen AM,Mikkelsen A,Christensen CB,Lip GY,Køber L,Torp-Pedersen C,Hansen ML

    更新日期:2013-09-10 00:00:00

  • Rationale and design of the International Verapamil SR/Trandolapril Study (INVEST): an Internet-based randomized trial in coronary artery disease patients with hypertension.

    abstract:OBJECTIVES:The primary objective of the International Verapamil SR/Trandolapril Study (INVEST) is to compare the risk for adverse outcomes (all-cause mortality, nonfatal myocardial infarction [MI] or nonfatal stroke) in hypertensive patients with coronary artery disease (CAD) treated with either a calcium antagonist-ba...

    journal_title:Journal of the American College of Cardiology

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.1016/s0735-1097(98)00423-9

    authors: Pepine CJ,Handberg-Thurmond E,Marks RG,Conlon M,Cooper-DeHoff R,Volkers P,Zellig P

    更新日期:1998-11-01 00:00:00

  • Graded myocardial ischemia is associated with a decrease in diastolic distensibility of the remote nonischemic myocardium in the anesthetized dog.

    abstract:OBJECTIVES:This study was designed to investigate the changes in regional distensibility of the ischemic segment and of a remote nonischemic segment brought about by graded myocardial ischemia. BACKGROUND:Ventricular distensibility is a major determinant of left ventricular end-diastolic pressure. The effects of grade...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章

    doi:10.1016/0735-1097(93)90209-j

    authors: Marsch SC,Wanigasekera VA,Ryder WA,Wong LS,Foëx P

    更新日期:1993-09-01 00:00:00

  • Incidence of bacteremia in transesophageal echocardiography: a prospective study of 140 consecutive patients.

    abstract::The incidence of bacteremia related to transesophageal echocardiography was studied in 140 consecutive patients (71 women and 69 men with a mean age of 53.7 +/- 15 years). Thirty-four patients had one or more prosthetic heart valves. Blood cultures were obtained from each patient through separate venipuncture sites im...

    journal_title:Journal of the American College of Cardiology

    pub_type: 临床试验,杂志文章,多中心研究

    doi:10.1016/0735-1097(91)90498-x

    authors: Melendez LJ,Chan KL,Cheung PK,Sochowski RA,Wong S,Austin TW

    更新日期:1991-12-01 00:00:00

  • Epicardial coronary artery tone and reactivity in patients with normal coronary arteriograms and reduced coronary flow reserve (syndrome X)

    abstract::The vasomotor response of proximal and distal angiographically normal coronary artery segments was studied in 12 patients with syndrome X, 17 age- and gender-matched patients with chronic stable angina and 10 control subjects with atypical chest pain and a normal coronary arteriogram. Ergonovine (300 micrograms by int...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章

    doi:10.1016/s0735-1097(10)80216-5

    authors: Kaski JC,Tousoulis D,Galassi AR,McFadden E,Pereira WI,Crea F,Maseri A

    更新日期:1991-07-01 00:00:00

  • Rational approach to use of heparin during cardiac catheterization in children.

    abstract:OBJECTIVES:We sought to determine an anticoagulation protocol for use during cardiac catheterization in children. BACKGROUND:There are few data to indicate which dose of heparin represents adequate anticoagulation or how best to monitor its efficacy. In this study, adequate anticoagulation was defined as the amount of...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章

    doi:10.1016/0735-1097(94)00438-V

    authors: Grady RM,Eisenberg PR,Bridges ND

    更新日期:1995-03-01 00:00:00

  • Cardiac troponin I levels and clinical outcomes in patients with acute coronary syndromes: the potential role of early percutaneous revascularization.

    abstract:OBJECTIVES:To establish the role of early catheter-based coronary intervention among patients sustaining acute coronary syndromes (ACS) stratified according to admission plasma troponin I (Tn-I) levels. BACKGROUND:The impact of early revascularization strategy on the clinical outcomes in patients with ACS stratified b...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章

    doi:10.1016/s0735-1097(99)00434-9

    authors: Fuchs S,Kornowski R,Mehran R,Satler LF,Pichard AD,Kent KM,Hong MK,Slack S,Stone GW,Leon MB

    更新日期:1999-11-15 00:00:00

  • Effects of n-3 polyunsaturated fatty acids on left ventricular function and functional capacity in patients with dilated cardiomyopathy.

    abstract:OBJECTIVES:This study was designed to test the effects of n-3 polyunsaturated fatty acids (PUFAs) on left ventricular (LV) systolic function in chronic heart failure (HF) due to nonischemic dilated cardiomyopathy (NICM). BACKGROUND:One hundred thirty-three patients with NICM and minimal symptoms on standard therapy we...

    journal_title:Journal of the American College of Cardiology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/j.jacc.2010.11.017

    authors: Nodari S,Triggiani M,Campia U,Manerba A,Milesi G,Cesana BM,Gheorghiade M,Dei Cas L

    更新日期:2011-02-15 00:00:00

  • Short- and long-term mortality for patients undergoing primary angioplasty for acute myocardial infarction.

    abstract:OBJECTIVES:The goal of this study was to learn more about the risk factors and short- and long-term outcomes for primary angioplasty. BACKGROUND:Primary angioplasty (direct angioplasty without antecedent thrombolytic therapy) has been an effective alternative to thrombolytic therapy for patients with acute myocardial ...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章,多中心研究

    doi:10.1016/s0735-1097(00)00866-4

    authors: Hannan EL,Racz MJ,Arani DT,Ryan TJ,Walford G,McCallister BD

    更新日期:2000-10-01 00:00:00

  • Electrical catheter ablation in the left and right ventricular wall in dogs: relation between delivered energy and histopathologic changes.

    abstract::Electrical catheter ablation of arrhythmogenic sites is now being used for the treatment of ventricular tachycardias. However, the extent and type of the ablation lesion in relation to energy level are controversial and not well known. In 10 beagles, single cathodal shocks of 30 (4 dogs), 80 (2 dogs) or 250 J (4 dogs)...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章

    doi:10.1016/s0735-1097(86)80194-2

    authors: Hauer RN,Straks W,Borst C,Robles de Medina EO

    更新日期:1986-09-01 00:00:00

  • Mapping of regional myocardial strain and work during ventricular pacing: experimental study using magnetic resonance imaging tagging.

    abstract:OBJECTIVES:The purpose of this study was to determine the spatial distribution of myocardial function (myofiber shortening and work) within the left ventricular (LV) wall during ventricular pacing. BACKGROUND:Asynchronous electrical activation, as induced by ventricular pacing, causes various abnormalities in LV funct...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章

    doi:10.1016/s0735-1097(99)00068-6

    authors: Prinzen FW,Hunter WC,Wyman BT,McVeigh ER

    更新日期:1999-05-01 00:00:00

  • Re-expansion of balloon-expandable stents after growth.

    abstract:OBJECTIVES:The purpose of this study was to evaluate the feasibility of re-expansion of balloon expandable intravascular stents and to examine the gross and histologic effects of re-expansion on vascular integrity. BACKGROUND:Intravascular stents have been used successfully as an adjunct to balloon dilation of congeni...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章

    doi:10.1016/0735-1097(93)90791-x

    authors: Morrow WR,Palmaz JC,Tio FO,Ehler WJ,VanDellen AF,Mullins CE

    更新日期:1993-12-01 00:00:00

  • Prevalence of electrocardiographic anomalies in young individuals: relevance to a nationwide cardiac screening program.

    abstract:OBJECTIVES:This study sought to investigate the prevalence of potentially abnormal electrocardiographic (ECG) patterns in young individuals to assess the implications for a nationwide screening program for conditions causing sudden cardiac death (SCD). BACKGROUND:The Italian experience suggests that pre-participation ...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章

    doi:10.1016/j.jacc.2014.01.046

    authors: Chandra N,Bastiaenen R,Papadakis M,Panoulas VF,Ghani S,Duschl J,Foldes D,Raju H,Osborne R,Sharma S

    更新日期:2014-05-20 00:00:00

  • Quality of life and exercise performance in patients in sinus rhythm versus persistent atrial fibrillation: a Veterans Affairs Cooperative Studies Program Substudy.

    abstract:OBJECTIVES:The purpose of this study was to determine quality of life (QOL) and exercise performance (EP) in patients with persistent atrial fibrillation (AF) converted to sinus rhythm (SR) compared with those remaining in or reverting to AF. BACKGROUND:Restoration of SR in patients with AF improving QOL and EP remain...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.jacc.2006.03.051

    authors: Singh SN,Tang XC,Singh BN,Dorian P,Reda DJ,Harris CL,Fletcher RD,Sharma SC,Atwood JE,Jacobson AK,Lewis HD Jr,Lopez B,Raisch DW,Ezekowitz MD,SAFE-T Investigators.

    更新日期:2006-08-15 00:00:00

  • Estimating Longitudinal Risks and Benefits From Cardiovascular Preventive Therapies Among Medicare Patients: The Million Hearts Longitudinal ASCVD Risk Assessment Tool: A Special Report From the American Heart Association and American College of Cardiolog

    abstract::The Million Hearts Initiative has a goal of preventing 1 million heart attacks and strokes-the leading causes of mortality-through several public health and healthcare strategies by 2017. The American Heart Association and American College of Cardiology support the program. The Cardiovascular Risk Reduction Model was ...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章

    doi:10.1016/j.jacc.2016.10.018

    authors: Lloyd-Jones DM,Huffman MD,Karmali KN,Sanghavi DM,Wright JS,Pelser C,Gulati M,Masoudi FA,Goff DC Jr

    更新日期:2017-03-28 00:00:00

  • Transplantation of Human Embryonic Stem Cell-Derived Cardiovascular Progenitors for Severe Ischemic Left Ventricular Dysfunction.

    abstract:BACKGROUND:In addition to scalability, human embryonic stem cells (hESCs) have the unique advantage of allowing their directed differentiation toward lineage-specific cells. OBJECTIVES:This study tested the feasibility of leveraging the properties of hESCs to generate clinical-grade cardiovascular progenitor cells and...

    journal_title:Journal of the American College of Cardiology

    pub_type: 临床试验,杂志文章

    doi:10.1016/j.jacc.2017.11.047

    authors: Menasché P,Vanneaux V,Hagège A,Bel A,Cholley B,Parouchev A,Cacciapuoti I,Al-Daccak R,Benhamouda N,Blons H,Agbulut O,Tosca L,Trouvin JH,Fabreguettes JR,Bellamy V,Charron D,Tartour E,Tachdjian G,Desnos M,Larghero J

    更新日期:2018-01-30 00:00:00

  • Prognostic value of N-terminal proatrial natriuretic factor plasma levels measured within the first 12 hours after myocardial infarction. Thrombolysis in Myocardial Infarction (TIMI) II Investigators.

    abstract:OBJECTIVES:The aim of the present study was to examine the relation between the plasma levels of the atrial peptide N-terminal proatrial natriuretic factor (proANF) measured during the 1st 12 h after myocardial infarction and 1-year mortality. BACKGROUND:The atrial peptides atrial natriuretic factor and N-terminal pro...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章

    doi:10.1016/0735-1097(95)00342-8

    authors: Hall C,Cannon CP,Forman S,Braunwald E

    更新日期:1995-11-15 00:00:00

  • The levoatriocardinal vein: morphology and echocardiographic identification of the pulmonary-systemic connection.

    abstract:OBJECTIVES:This study considers the array of pulmonary-systemic connections made by the levoatriocardinal vein. The primary and associated lesions that play a role in forming this vein are examined, and echocardiography is discussed as a method for its rapid identification. BACKGROUND:The levoatriocardinal vein is a p...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章,评审

    doi:10.1016/0735-1097(95)00283-X

    authors: Bernstein HS,Moore P,Stanger P,Silverman NH

    更新日期:1995-10-01 00:00:00

  • Electrophysiologic effects of sodium channel blockade on anisotropic conduction and conduction block in canine myocardium: preferential slowing of longitudinal conduction by flecainide versus disopyramide or lidocaine.

    abstract:OBJECTIVES:The purpose of this study was to determine the effects of sodium channel blockade on anisotropic excitation propagation in the intact canine left ventricle. BACKGROUND:Anisotropic ventricular conduction- electric conductivity dependent on the myocardial fiber direction-is one of the important mechanisms of ...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章

    doi:10.1016/s0735-1097(97)82543-0

    authors: Kondo T,Yamaki M,Kubota I,Tachibana H,Tomoike H

    更新日期:1997-06-01 00:00:00

  • Marine-derived n-3 fatty acids and atherosclerosis in Japanese, Japanese-American, and white men: a cross-sectional study.

    abstract:OBJECTIVES:We sought to examine whether marine-derived n-3 fatty acids are associated with less atherosclerosis in Japanese versus white populations in the U.S. BACKGROUND:Marine-derived n-3 fatty acids at low levels are cardioprotective through their antiarrhythmic effect. METHODS:A population-based cross-sectional ...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章

    doi:10.1016/j.jacc.2008.03.047

    authors: Sekikawa A,Curb JD,Ueshima H,El-Saed A,Kadowaki T,Abbott RD,Evans RW,Rodriguez BL,Okamura T,Sutton-Tyrrell K,Nakamura Y,Masaki K,Edmundowicz D,Kashiwagi A,Willcox BJ,Takamiya T,Mitsunami K,Seto TB,Murata K,White RL

    更新日期:2008-08-05 00:00:00

  • A mutation in CALM1 encoding calmodulin in familial idiopathic ventricular fibrillation in childhood and adolescence.

    abstract:OBJECTIVES:This study aimed to identify the genetic defect in a family with idiopathic ventricular fibrillation (IVF) manifesting in childhood and adolescence. BACKGROUND:Although sudden cardiac death in the young is rare, it frequently presents as the first clinical manifestation of an underlying inherited arrhythmia...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章

    doi:10.1016/j.jacc.2013.07.091

    authors: Marsman RF,Barc J,Beekman L,Alders M,Dooijes D,van den Wijngaard A,Ratbi I,Sefiani A,Bhuiyan ZA,Wilde AA,Bezzina CR

    更新日期:2014-01-28 00:00:00

  • Cardiomyocyte hypertrophy, oncosis, and autophagic vacuolization predict mortality in idiopathic dilated cardiomyopathy with advanced heart failure.

    abstract:OBJECTIVES:The aim of this study was to identify the remodeling parameters cardiomyocyte (CM) damage or death, hypertrophy, and fibrosis that may be linked to outcomes in patients with advanced heart failure (HF) in an effort to understand the pathogenic mechanisms of HF that may support newer therapeutic modalities. ...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章

    doi:10.1016/j.jacc.2010.09.080

    authors: Vigliano CA,Cabeza Meckert PM,Diez M,Favaloro LE,Cortés C,Fazzi L,Favaloro RR,Laguens RP

    更新日期:2011-04-05 00:00:00

  • Subcutaneous administration of brain natriuretic peptide in experimental heart failure.

    abstract:OBJECTIVES:The objective of this investigation was to define for the first time the cardiorenal and humoral actions of repeated short-term administration of subcutaneous (SQ) brain natriuretic peptide (BNP) administration during the evolution of experimental heart failure. BACKGROUND:The rationale of this study was ba...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章

    doi:10.1016/s0735-1097(00)00911-6

    authors: Chen HH,Grantham JA,Schirger JA,Jougasaki M,Redfield MM,Burnett JC Jr

    更新日期:2000-11-01 00:00:00

  • Right coronary artery-pulmonary artery arteriovenous fistula secondary to open heart surgery.

    abstract::A patient is described who underwent atrial septal defect repair at age 12 and presented 16 years later with angina. Coronary angiography revealed a right coronary artery to pulmonary artery fistula that had developed at the site of the previous thoracotomy. This is the first report of an acquired fistula of this type...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章

    doi:10.1016/s0735-1097(85)80509-x

    authors: Rothschild AH,Adatepe MH,Magovern GJ,Rothschild MA,Joyner CR

    更新日期:1985-10-01 00:00:00