Abstract:
:Trichomonas vaginalis (TV) rates in women are increasing and many are asymptomatic. Nucleic acid amplification tests (NAATs) are becoming the 'gold standard' for diagnosis. We aimed to establish our asymptomatic TV rates by testing all women attending Oxfordshire's Sexual Health service, regardless of symptoms, using the BD ProbeTec™ TV Qx NAATs (BDQx). During BDQx's verification process, the sensitivity and specificity were calculated using results of 220 endocervical samples from symptomatic women, compared with culture. BDQx was subsequently implemented and prospectively evaluated over 6 months in female attendees. Wet mount microscopy was also performed in symptomatics. Demographic and clinical characteristics of those diagnosed were analysed. From 220 samples tested by BDQx and culture: 5 were positive on both and one solely using BDQx, giving a sensitivity and specificity of 100% and 99.53%, respectively. In the prospective cohort, of 5775 BDQx tests, 33 (0.57%) were positive. 11/33 (33%) patients were asymptomatic. All patients diagnosed had risk factors: age >25 years (85%), residence in a deprived area (79%) and black ethnicity (21%). Despite BDQx being highly sensitive and specific, with our low TV prevalence universal screening may not be justified. Targeted screening using local demographic data merits further investigation.
journal_name
Int J STD AIDSjournal_title
International journal of STD & AIDSauthors
Lord E,Newnham T,Dorrell L,Jesuthasan G,Clarke L,Jeffery K,Sherrard Jdoi
10.1177/0956462416649888subject
Has Abstractpub_date
2017-03-01 00:00:00pages
357-361issue
4eissn
0956-4624issn
1758-1052pii
0956462416649888journal_volume
28pub_type
杂志文章abstract::The objective of this paper was to identify and describe enhanced sexual health services (ESHSs) commissioned for testing, diagnosis and management of sexually transmitted infections (STIs) in primary and community care settings in England. ESHSs commissioned by Primary Care Trusts (PCTs) in England were determined by...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/ijsa.2010.010198
更新日期:2010-09-01 00:00:00
abstract::This study describes antimicrobial susceptibility patterns of Neisseria gonorrhoeae isolates obtained from female sex workers in Cotonou, Bénin. All isolates were susceptible to spectinomycin, ceftriaxone and ciprofloxacin, and susceptible to moderately susceptible to kanamycin; 9.8% of isolates were resistant to thia...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/0956462011916848
更新日期:2001-02-01 00:00:00
abstract::This study examined the health risk profile of prostitutes in Dublin. Clinical records of all 150 new prostitutes who attended a drop-in clinic for prostitutes in Dublin city during the period 1991-1997 were reviewed. Variables examined included: age, use of injectable drugs, human immunodeficiency virus (HIV) status,...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/0956462981922557
更新日期:1998-08-01 00:00:00
abstract::Self sampling of the secretions of the female genital tract for microbiological investigations for Neisseria gonorrhoeae, Chlamydia trachomatis and Trichomonas vaginalis was assessed in female attenders of the genitourinary medicine clinic in Coventry and Warwickshire Hospital. The purpose of the study was to evaluate...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/095646249400500411
更新日期:1994-07-01 00:00:00
abstract::To elicit the needs of asylum seekers attending the Royal Hallamshire genitourinary medicine clinic for the first time in 2002 and whether these differed from British patients, a search of patient records for 2002 identified 43 asylum seekers (21 female, 22 male) who were paired with 43 British patients matched by age...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/0956462041558230
更新日期:2004-08-01 00:00:00
abstract::The first HIV-positive diagnosis among injecting drug users (IDU) in Glasgow was made in 1985. By the end of 1987 prevalence among IDU receiving voluntary attributable tests was 4.8%. Since 1990, an annual cross-sectional survey of HIV prevalence and risk behaviours among 500 current Glasgow IDU has provided a more re...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/095646249400500205
更新日期:1994-03-01 00:00:00
abstract::Chancroid is a sexually acquired disease caused by Haemophilus ducreyi. The infection is characterized by one or more genital ulcers, which are soft and painful, and regional lymphadenitis which may develop into buboes. The infection may easily be misidentified due to its rare occurrence in Europe and difficulties in ...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章,实务指引
doi:10.1258/ijsa.2010.010432
更新日期:2011-05-01 00:00:00
abstract::The aetiology of chronic prostatitis is poorly understood. A cross-sectional study of a population of male undergraduates in Nigeria, using a questionnaire containing the National Institutes of Health Chronic Prostatitis Symptom Index (NIH-CPSI) and some other relevant sex-related questions, was conducted. A total of ...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/ijsa.2010.010317
更新日期:2011-02-01 00:00:00
abstract::We evaluated associations between history of syphilis infection and both cognitive function and depressive symptoms in people living with HIV (PLHIV) and comparable HIV-negative controls. Syphilis serological tests, cognitive function and depression were assessed in PLHIV and controls participating in the Pharmacokine...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/0956462418817612
更新日期:2019-04-01 00:00:00
abstract::The purpose of this study was to investigate whether Epstein-Barr virus (EBV) is associated with acetowhite lesions of the portio cervix, demonstrating koilocytosis and/or cervical intraepithelial neoplasia (CIN) I-III. The study group comprised 37 women admitted to the Department of Gynaecology and Obstetrics, Sahlgr...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/0956462971920488
更新日期:1997-07-01 00:00:00
abstract::A pre-treatment and a 3-week post-treatment isolate of Neisseria gonorrhoeae from a 13-year-old boy treated with azithromycin in a single 1 g oral dose were characterized microbiologically. Both isolates were of the same serovar/auxotype (1B6/non-requiring) and had similar antibiograms apart from erythromycin and azit...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/0956462971920127
更新日期:1997-05-01 00:00:00
abstract::Despite many reports of HIV-infected African children who have HIV-uninfected mothers, little is known about the extent and modes of horizontal HIV transmission in African children. We estimated the extent of horizontal HIV transmission in Swazi children by comparing child and mother HIV statuses in the 2006-2007 Swaz...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/ijsa.2009.009204
更新日期:2009-12-01 00:00:00
abstract::The Senegal pre-exposure prophylaxis (PrEP) Demonstration Project was an open-label cohort study assessing the delivery of daily oral PrEP to HIV-negative female sex workers (FSWs) in four Ministry of Health (MoH)-run clinics in Dakar, Senegal. We assessed uptake, retention in care, and adherence over up to 12 months ...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/0956462420943704
更新日期:2020-10-01 00:00:00
abstract::Alterations in body shape due to fat loss and/or redistribution have been described in HIV-infected individuals and associated with the use of antiretroviral (ARV) combination therapy. Certain of these changes have been referred to as peripheral lipodystrophy (LD) and we describe 12 patients who were recognized with t...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/0956462981921189
更新日期:1998-10-01 00:00:00
abstract::Understanding the epidemiologic definition of epidemic versus non-epidemic spread of an infectious disease agent and the different patterns of heterosexual HIV transmission are needed to fully understand the low potential for heterosexual HIV epidemics in most heterosexual populations. Epidemic sexual HIV transmission...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章,评审
doi:10.1258/095646207781439667
更新日期:2007-08-01 00:00:00
abstract::Post-exposure prophylaxis (PEP) is a promising but under-utilized strategy for HIV prevention in high-risk populations. Between March 2010 and June 2011, two community-based clinics in Los Angeles County provided PEP in a pilot program to 267 unique individuals. Courses were primarily dispensed to men who have sex wit...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/0956462417743158
更新日期:2018-05-01 00:00:00
abstract::Sweden was the first country to introduce online Chlamydia trachomatis testing for both men and women and this article provides information about the user characteristics and which risk groups are reached with this method. During the years 2005-2007 a questionnaire was administered with a response rate of 86% (n = 602...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/ijsa.2011.011030
更新日期:2012-02-01 00:00:00
abstract::The expense in time and money limit the use of randomized clinical trials (RCT) and cohort studies for evaluating long-term AIDS treatment outcomes. We conducted a case-control study to characterize predictors of AIDS mortality after the availability of highly active antiretroviral therapy (HAART) in San Francisco, in...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/ijsa.2008.008381
更新日期:2009-05-01 00:00:00
abstract::Studies in various regions of the world have shown that women infected with HIV-1 are at increased risk for cervical human papillomavirus (HPV) infection as well as for cervical cancer precursor lesions. HIV infection and cervical cancer are both widespread in West Africa, but little is known about the relationship be...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/095646249400500307
更新日期:1994-05-01 00:00:00
abstract::We describe a case of cryptococcal meningitis in a patient known to have HIV who presented initially with ocular cryptococcosis. This case highlights to clinicians the need to be aware of this association and to carry out relevant investigations so as to treat these patients appropriately. ...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/ijsa.2009.009132
更新日期:2012-05-01 00:00:00
abstract::We present a case of acute limbic encephalitis secondary to HIV seroconversion. The patient made a gradual neurological recovery following treatment with antiretroviral therapy, steroids and intravenous immunoglobulin. ...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/ijsa.2011.010331
更新日期:2011-04-01 00:00:00
abstract::We assessed the validity of self-reported sex and condom use by comparing self-reports with prostate-specific antigen (PSA) detection in a prospective study of 210 female sex workers in Mombasa, Kenya. Participants were interviewed on recent sexual behaviours at baseline and 12-month follow-up visits. At both visits, ...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/095646207779949899
更新日期:2007-01-01 00:00:00
abstract::We examined health-care seeking practices among patients with sexually transmitted diseases (STDs) in south China. In 1995, we recruited a consecutive sample of 939 STD patients attending the STD clinics of the Municipal STD Control Centers of Guangzhou and Shenzhen, 'special economic zones' near Hong Kong. Attending ...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/0956462991914177
更新日期:1999-05-01 00:00:00
abstract::During the mid-1980s Australia experienced a remarkable decline in HIV incidence that can rightly be considered a public health milestone of global importance. The effects of this decline lasted for about 20 years and greatly benefited all Australians. In contrast, as we enter the mid-2000s, we see the global epidemic...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章,评审
doi:10.1258/095646206779307612
更新日期:2006-12-01 00:00:00
abstract::Whilst much is known about the individual-level risk factors for herpes simplex virus 2 (HSV-2) infection, little is known about why only some populations develop generalized HSV-2 epidemics. This study aims to assess the extent to which partner-concurrency (a factor which operates at both the partnership- and network...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/0956462413482810
更新日期:2013-10-01 00:00:00
abstract::Requests for hepatitis C antibodies (HCV Ab) made by the Oxford Department of Genito-urinary (GU) Medicine were audited against national guidelines to determine how the service performed and to develop locally applicable standards. This resulted in more effective screening and cost savings. ...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/095646206777689026
更新日期:2006-07-01 00:00:00
abstract::The management of cases of gonorrhoea in the Genitourinary Medicine Department (GUM) of Newcastle upon Tyne in 1999 was audited. The sensitivity of microscopy in diagnosis was 90.4% for male urethral gonorrhoea and 26.6% for female genital gonorrhoea. The sensitivity of laboratory culture was 98.5%. Screening for Chla...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/0956462001915057
更新日期:2000-10-01 00:00:00
abstract::Premature ejaculation is a common sexual problem which presents to genitourinary (GU) medicine services. Five main treatment approaches have been used in clinical trials: behavioural therapy, antidepressants, phosphodiesterase-5 (PDE5) inhibitors, topical anaesthetic agents and alpha-blockers. We have carried out a sy...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章,评审
doi:10.1258/095646205774357299
更新日期:2005-10-01 00:00:00
abstract::This study compared the distributions of known human immunodeficiency virus (HIV) and acute hepatitis B virus (HBV) infection among drug injectors in Glasgow over a 3.5 year period. Data were obtained from all relevant laboratory request forms submitted to Glasgow's 3 virology laboratories during the period 1 January ...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/095646249100200509
更新日期:1991-09-01 00:00:00
abstract::The aim of the study was to provide more comprehensive data on the clinical characteristics of hospitalized AIDS patients in Cambodia. Chart review of 381 HIV-infected patients admitted to a public hospital in Phnom Penh, Cambodia between December 1999 and May 2000 was performed. The in-hospital mortality rate was 43....
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/095646203765371312
更新日期:2003-06-01 00:00:00