Abstract：
:Alterations in body shape due to fat loss and/or redistribution have been described in HIV-infected individuals and associated with the use of antiretroviral (ARV) combination therapy. Certain of these changes have been referred to as peripheral lipodystrophy (LD) and we describe 12 patients who were recognized with this condition between September 1997 and February 1998. It occurred in 12.5% of patients on ARV combination therapy that included a protease inhibitor (PI). In early descriptions the emphasis was on the abdomen, which may be grossly enlarged. In our patients this feature was much less marked. Patients with LD were significantly older than those on PI therapy who did not develop this condition (P=0.016). Although all had raised triglyceride (TG) levels, the elevations were not severe (maximum=6.3 mmol/l). CD4 lymphocyte and viral load levels suggested an optimal response to ARV therapy at the time LD developed. Appearances may be disfiguring but no serious systemic consequences of LD have been observed. Most individuals have chosen to remain on their present ARV combinations. When LD occurs, it appears to be a marker of effective response to anti-HIV therapy.
journal_name
Int J STD AIDSjournal_title
International journal of STD & AIDSauthors
Shaw AJ,McLean KA,Evans BAdoi
10.1258/0956462981921189subject
Has Abstractpub_date
1998-10-01 00:00:00pages
595-9issue
10eissn
0956-4624issn
1758-1052journal_volume
9pub_type
杂志文章abstract：:In this structured review, we evaluated purulent vaginal and cervical discharge as diagnostic tests for pelvic inflammatory disease (PID). Using a pretest probability of PID (diagnosed clinically) of 50%, we used the odds-likelihood formulation of Bayes' theorem to calculate post-test probabilities of PID (proven by l...
journal_title：International journal of STD & AIDS
pub_type： 杂志文章,评审
doi：10.1258/ijsa.2008.008261
更新日期：2009-02-01 00:00:00
abstract：:The World Health Organization expects the rate of new HIV infections to decline in all global regions before the year 2005, except in South East Asia. More than 3 million people become HIV infected each year in South East Asia. It is incorrect to discuss it as a whole since the cultures in the region are so differen...
journal_title：International journal of STD & AIDS
pub_type： 杂志文章
doi：10.1258/0956462961917681
更新日期：1996-01-01 00:00:00
abstract：:An innovative six-month, two sessions a week, funded clinical attachment programme was devised and introduced for practical training and experience to meet the demands and requirements of those wishing practical experience and training in genitourinary medicine. This has been generated by interest from previous theore...
journal_title：International journal of STD & AIDS
pub_type： 杂志文章
doi：10.1258/0956462041211234
更新日期：2004-07-01 00:00:00
abstract：:Sexually transmitted infections (STIs) in Vietnam have been increasing. Control of STIs among female sex workers (FSWs) is important in controlling the epidemic. Effective STI control requires that physicians are skilful in taking sexual history for FSW patients. Three hundred and seventy-one physicians responded to a...
journal_title：International journal of STD & AIDS
pub_type： 杂志文章
doi：10.1177/0956462414529553
更新日期：2015-01-01 00:00:00
abstract：:During the mid-1980s Australia experienced a remarkable decline in HIV incidence that can rightly be considered a public health milestone of global importance. The effects of this decline lasted for about 20 years and greatly benefited all Australians. In contrast, as we enter the mid-2000s, we see the global epidemic...
journal_title：International journal of STD & AIDS
pub_type： 杂志文章,评审
doi：10.1258/095646206779307612
更新日期：2006-12-01 00:00:00
abstract：:We assessed prevalence of human immunodeficiency virus (HIV) risk behaviors and depressive symptoms among adolescent girls and young women (AGYW) aged 15-24 years attending four public family planning clinics in Western Kenya from January to June 2019. Moderate-to-severe depression (MSD) was defined as a Center for Ep...
journal_title：International journal of STD & AIDS
pub_type： 杂志文章
doi：10.1177/0956462420920423
更新日期：2020-06-01 00:00:00
abstract：:Detection of Haemophilus ducreyi in genital ulcer specimens by culture lacks sensitivity. To enhance detection, a heminested polymerase chain reaction (PCR) assay was developed targeting the nucleotide sequence of a gene, designated p27, which encodes for a 27 kDa H. ducreyi-specific protein. The p27 PCR assay detecte...
journal_title：International journal of STD & AIDS
pub_type： 杂志文章
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更新日期：2001-12-01 00:00:00
abstract：:This study of sexual behaviour in the city of Lisbon is based on data obtained from 2 random samples, one of individuals aged 16-20 (n = 400) and another of individuals over the age of 20 (n = 400). Samples have been stratified by district, gender and age. Data were obtained by personal interview and by questionnaires...
journal_title：International journal of STD & AIDS
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1177/095646249500600108
更新日期：1995-01-01 00:00:00
abstract：:During 2001 and 2002 an anonymous outreach-screening programme in Melbourne, Australia, offered testing for gonorrhoea and chlamydia on-site at men-only saunas. Modifications were made to this screening programme to offer a comprehensive testing clinic for sexually transmissible infections (STIs), including HIV. The c...
journal_title：International journal of STD & AIDS
pub_type： 杂志文章
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更新日期：2005-12-01 00:00:00
abstract：:Advancements in the diagnosis and treatment of testicular cancer now give a five-year survival rate of 97.2%. Delayed presentation remains the primary cause of poor outcome and recommendations have stressed that men, particularly those with risk factors, should undertake regular testicular self-examination. This study...
journal_title：International journal of STD & AIDS
pub_type： 杂志文章
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更新日期：2014-10-01 00:00:00
abstract：:A 46-year-old Caucasian heterosexual male was referred to a dedicated AIN clinic from colorectal multidisciplinary meeting (MDM) with AIN 3 following complete resection of anal squamous cell carcinoma (SCC). On further questioning, he revealed that he also had a lesion on his penis. Histology of the penile lesion demo...
journal_title：International journal of STD & AIDS
pub_type： 杂志文章
doi：10.1258/ijsa.2011.011255
更新日期：2012-04-01 00:00:00
abstract：:Racial/ethnic minorities in the Southeastern USA are disproportionately affected by HIV, and would benefit from a preventive vaccine. We conducted a cross-sectional survey of 220 community college students in Atlanta to evaluate racial/ethnic differences in knowledge and willingness to participate in HIV vaccine trial...
journal_title：International journal of STD & AIDS
pub_type： 杂志文章
doi：10.1258/095646206775455667
更新日期：2006-02-01 00:00:00
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journal_title：International journal of STD & AIDS
pub_type： 杂志文章
doi：10.1177/0956462414531240
更新日期：2015-02-01 00:00:00
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journal_title：International journal of STD & AIDS
pub_type： 杂志文章
doi：10.1177/0956462420915394
更新日期：2020-07-01 00:00:00
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journal_title：International journal of STD & AIDS
pub_type： 杂志文章
doi：10.1258/ijsa.2011.011173
更新日期：2012-03-01 00:00:00
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journal_title：International journal of STD & AIDS
pub_type： 杂志文章
doi：10.1258/ijsa.2008.008348
更新日期：2009-04-01 00:00:00
abstract：:The first national audit of the management of Chlamydia trachomatis was undertaken by non-consultant career grade doctors working in genitourinary (GU) medicine clinics in the UK. During the audit period of January--March 2004, 1670 data collection forms were completed (from 830 men and 840 women with chlamydia). In a...
journal_title：International journal of STD & AIDS
pub_type： 杂志文章
doi：10.1258/0956462054308431
更新日期：2005-07-01 00:00:00
abstract：:Five hundred and twenty consecutive women newly attending a genitourinary medicine clinic who participated in a study of sexual behaviour were also tested for type-specific antibody to herpes simplex virus type 2; 135 (26%) were seropositive, of whom only 29 (21.5%) had had clinical evidence of genital herpes. Seropos...
journal_title：International journal of STD & AIDS
pub_type： 杂志文章
doi：10.1258/095646203321043237
更新日期：2003-01-01 00:00:00
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journal_title：International journal of STD & AIDS
pub_type： 杂志文章
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journal_title：International journal of STD & AIDS
pub_type： 杂志文章
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更新日期：2016-10-01 00:00:00
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journal_title：International journal of STD & AIDS
pub_type： 杂志文章
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journal_title：International journal of STD & AIDS
pub_type： 杂志文章
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更新日期：2004-02-01 00:00:00
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journal_title：International journal of STD & AIDS
pub_type： 杂志文章
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更新日期：2016-10-01 00:00:00
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journal_title：International journal of STD & AIDS
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更新日期：2017-10-01 00:00:00
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journal_title：International journal of STD & AIDS
pub_type： 杂志文章
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更新日期：2012-03-01 00:00:00
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journal_title：International journal of STD & AIDS
pub_type： 杂志文章
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更新日期：2009-01-01 00:00:00
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journal_title：International journal of STD & AIDS
pub_type： 杂志文章
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更新日期：1999-06-01 00:00:00
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journal_title：International journal of STD & AIDS
pub_type： 杂志文章,评审
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更新日期：2010-01-01 00:00:00
abstract：:Women attending a dedicated medical gynaecology and family planning referral clinic for women with HIV were surveyed using a standard questionnaire about their knowledge and attitudes to post-exposure prophylaxis after sexual exposure (PEPSE) and emergency hormonal contraception (EHC). Eighty percent of them had not h...
journal_title：International journal of STD & AIDS
pub_type： 杂志文章
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更新日期：2008-01-01 00:00:00
abstract：:Measurement of HIV viral load (VL) is the best indicator of success of antiretroviral therapy. We investigated the correlation between results by the Cepheid GeneXpert and a standard of care VL assay (Abbott M2000). This was a prospective study of people living with HIV who attended the department for routine VL measu...
journal_title：International journal of STD & AIDS
pub_type： 杂志文章
doi：10.1177/0956462420975606
更新日期：2021-01-09 00:00:00
