Abstract:
:The USA and international recommendations no longer emphasize using risk factors to target groups for HIV-testing. Using a Guatemalan database of HIV tests, we developed a clinical prediction rule to guide decisions on HIV-testing. Prior to HIV-testing, data were collected on demographics, risk factors and prior testing. Based on a theoretical construct incorporating demographics, known HIV risk factors and symptoms, we developed a logistic regression model to predict HIV seropositivity. Between 2000 and 2005, 16,471 tests were performed, of which 19.8% were positive. The algorithm successfully predicted 1883 of 2489 HIV-positive tests (sensitivity 76%, likelihood ratio [LR]-positive 2.45) and 6282 of 9086 HIV-negative tests (specificity 69%, LR-negative 0.35). Although the model indices are robust, applying the model in a clinical setting would have little impact on improving selective testing practices. Our findings support current recommendations for universal HIV-testing, not selective testing based on risk factors. Before these recommendations can be adopted widely in Guatemala, treatment access needs to be assured and protections put in place for people diagnosed with HIV infection.
journal_name
Int J STD AIDSjournal_title
International journal of STD & AIDSauthors
Anderson MR,Samayoa B,O'Sullivan LF,Fletcher J,Arathoon Edoi
10.1258/ijsa.2008.008223subject
Has Abstractpub_date
2009-01-01 00:00:00pages
30-4issue
1eissn
0956-4624issn
1758-1052pii
20/1/30journal_volume
20pub_type
杂志文章abstract::South Africa has a massive burden of HIV and alcohol disease, and these pandemics are inextricably linked. Much evidence indicates that alcohol independently influences decisions around sex, and undermines skills for condom negotiation and correct use. Thus, not surprisingly, people with problem drinking in Africa hav...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章,评审
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abstract::Acute epididymo-orchitis is a common cause of 'acute scrotum' in adolescence and young adults, and the common causative pathogens are Chlamydia trachomatis and Neisseria gonorrhoeae. This is a rare case of acute epididymo-orchitis due to Pseudomonas aeruginosa in a pubertal boy with a history of 'ano-receptive' interc...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
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abstract::The Russian Federation has had a well developed state system for the surveillance and control of sexually transmitted diseases (STDs) since World War II. The system is centered around clinical dermatovenereology (DV) services controlled by the Ministry of Health, and in the regions by the Divisions of Health Care. D...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:
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journal_title:International journal of STD & AIDS
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abstract::We aim to assess the usefulness of the cytomegalovirus (CMV) pp65 antigenaemia test, also called the CMV direct antigen test (DAT), in the management of patients with advanced human immunodeficiency virus (HIV) infection; we studied all patients who had pp65 assays between 8 September 1995 and 30 August 1996. Twenty-t...
journal_title:International journal of STD & AIDS
pub_type: 临床试验,杂志文章
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更新日期:1998-09-01 00:00:00
abstract::A cross-sectional study of 360 patients presenting with sexually transmitted diseases (STDs) to a primary care clinic in KwaZulu/Natal, South Africa was done. Prevalence of HIV infection was 42.5%. HIV-infected patients were of similar age to uninfected patients (mean age 25.1 vs 26.1 years), but were less likely to b...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
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journal_title:International journal of STD & AIDS
pub_type: 杂志文章,评审
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更新日期:2001-04-01 00:00:00
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journal_title:International journal of STD & AIDS
pub_type: 杂志文章,评审
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journal_title:International journal of STD & AIDS
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
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journal_title:International journal of STD & AIDS
pub_type: 杂志文章
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journal_title:International journal of STD & AIDS
pub_type: 杂志文章,评审
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journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/0956462991914762
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journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/ijsa.2008.008053
更新日期:2008-11-01 00:00:00
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journal_title:International journal of STD & AIDS
pub_type: 杂志文章
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pub_type: 杂志文章
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journal_title:International journal of STD & AIDS
pub_type: 杂志文章,meta分析
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更新日期:2008-10-01 00:00:00
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journal_title:International journal of STD & AIDS
pub_type: 杂志文章
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pub_type: 杂志文章
doi:10.1258/0956462991914456
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journal_title:International journal of STD & AIDS
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journal_title:International journal of STD & AIDS
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pub_type: 杂志文章,评审
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journal_title:International journal of STD & AIDS
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journal_title:International journal of STD & AIDS
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journal_title:International journal of STD & AIDS
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