Abstract:
:The aim of the study was to determine in a rural population the age- and sex-specific prevalence and incidence rates of serological reactivity of 5 common sexually transmitted diseases (STDs) and their association with HIV-1 antibody status. Of the adult population of two villages (529 adults aged 15 years or more) 294 provided an adequate blood specimen both on enrollment and at 12 months. The sera were tested at 3 collaborating laboratories for antibodies against HIV-1, Treponema pallidum, Haemophilus ducreyi, Chlamydia trachomatis and herpes simplex virus type 1 (HSV-1) and type 2 (HSV-2). A sample of 45 children were tested for HSV-1 and HSV-2. Seroprevalence rates in adults on enrollment were 7.8% for HIV-1, 10.8% for active syphilis, 10.4% for H. ducreyi, 66.0% for C. trachomatis, 91.2% for HSV-1 and 67.9% for HSV-2. Males were significantly more likely than females to be seropositive for H. ducreyi (15.6% versus 6.6%), but less likely to be HSV-2 antibody positive (57.0% versus 74.4%). Reactivity to H. ducreyi, C. trachomatis and HSV-2 rose with increasing age. In contrast, active syphilis showed no age trend. All STDs tended to be more common in those HIV-1 seropositive. Incidence rates over the 12 months were nil for HIV-1, 0.5% for syphilis, 1.2% for H. ducreyi, 11.3% for C. trachomatis, and 16.7% for HSV-2. The results of this exploratory study indicate that all STDs included are common in this rural population. The high HSV-2 prevalence rate among adolescents suggests that HSV-2 may be an important risk factor for HIV-1 infection.(ABSTRACT TRUNCATED AT 250 WORDS) :A seroprevalence survey conducted in rural Uganda revealed a high potential for interaction between sexually transmitted diseases (STDs) such as herpes simplex virus type 2 (HSV-2) and human immunodeficiency virus (HIV). Venous blood samples were collected at baseline and one year later from 294 randomly selected adults aged 15 years or over from two neighboring villages. At baseline, 23 (7.8%) adults were HIV-positive; no seroconversion occurred during the one-year study period. STD prevalence rates were 10.8% for syphilis, 10.4% for Hemophilus ducreyi, 66.0% for Chlamydia trachomatis, and 91.2% for HSV-1 and 67.9% for HSV-2. More females (74.4%) than males (57.0%) were HSV-2 antibody-positive. Reactivity to H. ducreyi, C. trachomatis, and HSV-2 rose with increasing age, but there was no such trend for syphilis. HIV prevalence rates were 0.0% among those with no serologic evidence of previous STDs, 2.6% among those with one or two prior STDs, and 20.0% among those with three or four STD markers. Of particular concern was the high rate of HSV-2 prevalence among adolescents (85% among females aged 20-24 years and 82% in males aged 25-29 years). It is suggested that age-specific HSV-2 seroprevalence can provide an accurate marker of premarital sexual activity among Ugandan adolescents since it lacks the potential for bias associated with self-reporting in this population.
journal_name
Int J STD AIDSjournal_title
International journal of STD & AIDSauthors
Wagner HU,Van Dyck E,Roggen E,Nunn AJ,Kamali A,Schmid DS,Dobbins JG,Mulder DWdoi
10.1177/095646249400500509subject
Has Abstractpub_date
1994-09-01 00:00:00pages
332-7issue
5eissn
0956-4624issn
1758-1052journal_volume
5pub_type
杂志文章abstract::Australian and New South Wales Sexually Transmissible Infections Strategies recommend sexual health clinics actively target particular populations, including men who have sex with men (MSM), who have increasing rates of sexually transmitted infections (STIs). We describe trends in MSM attendances, STI testing and diag...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/ijsa.2010.010458
更新日期:2011-06-01 00:00:00
abstract::Using data from eligible participants, we evaluated procedures of a multi-step enrollment process for an mHealth, pilot randomized controlled trial aimed to promote regular HIV testing among at-risk, diverse sexual minority men. Completion rates of eligible participants were calculated and characterized for these enro...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/0956462419831854
更新日期:2019-06-01 00:00:00
abstract::To elicit the needs of asylum seekers attending the Royal Hallamshire genitourinary medicine clinic for the first time in 2002 and whether these differed from British patients, a search of patient records for 2002 identified 43 asylum seekers (21 female, 22 male) who were paired with 43 British patients matched by age...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/0956462041558230
更新日期:2004-08-01 00:00:00
abstract::Errors and problems associated with male condom use are very prevalent and increase the likelihood of inconsistent and incomplete use, thereby compromising condom effectiveness. The aim of this study was to assess the perceived benefits of a new condom wrapper/integrated applicator designed to reduce barriers to condo...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/0956462418803491
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abstract::With the increasing incidence of chronic kidney disease in patients with human immunodeficiency virus (HIV), the number of HIV-infected patients requiring hemodialysis has also increased. Dolutegravir is an integrase inhibitor that is a common component of HIV treatment regimens. Currently, there is no guidance regard...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
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更新日期:2019-05-01 00:00:00
abstract::We report two cases who attended the genitourinary medicine clinic for the treatment of epididymo-orchitis. They did not respond to treatment and subsequent ultrasound sonography (USS) of testis confirmed microlithiasis and excluded any inflammatory process or carcinoma in situ. Because of its association with testicu...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/ijsa.2007.007184
更新日期:2008-04-01 00:00:00
abstract::Patients who acquire repeated infections of gonorrhoea are well described. A study was undertaken of male patients attending a central London clinic in an attempt to identify features of those acquiring repeated infections to facilitate risk reduction strategies. During the 3 years 1990 to 1992, 18.8% of patients cont...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/0956462961917807
更新日期:1996-07-01 00:00:00
abstract::During 2001 and 2002 an anonymous outreach-screening programme in Melbourne, Australia, offered testing for gonorrhoea and chlamydia on-site at men-only saunas. Modifications were made to this screening programme to offer a comprehensive testing clinic for sexually transmissible infections (STIs), including HIV. The c...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/095646205774988163
更新日期:2005-12-01 00:00:00
abstract::HIV-infected women have a high prevalence of abnormal Papanicolaou smears and cervical intraepithelial neoplasia. A multiparametric analysis of epidemiological and behavioural risk factors has been performed in a cohort of 204 HIV-infected women in an outpatient clinic with the aim to investigate risk factors associat...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/0956462971920316
更新日期:1997-06-01 00:00:00
abstract::For people immunosuppressed by human immunodeficiency virus (HIV), we expect an increase in cancer incidence similar to that documented in transplant patients. We examined the cancer spectrum in an HIV-infected cohort, specifically malignancies not currently associated with acquired immunodeficiency syndrome (AIDS), i...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/0956462991913574
更新日期:1999-12-01 00:00:00
abstract::Community viral load is an aggregate measure of HIV viral load in a particular geographic location, community, or subgroup. Community viral load provides a measure of disease burden in a community and community transmission risk. This study aims to examine community viral load trend in South Carolina and identify diff...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/0956462416642349
更新日期:2017-03-01 00:00:00
abstract::Vulval adhesion is a rare but recognized local complication following genital herpes infection. We believe this is only the second reported case of successful resolution of vulval herpetic adhesion using topical potent corticosteroid as the primary early treatment. ...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/ijsa.2007.007099
更新日期:2008-01-01 00:00:00
abstract::In a previous internal audit of women attending the department of genitourinary medicine following rape, we noted that data from diagnostic coding seemed to underestimate the problem and that anecdotally, a number of women had been seen with concerns relating to historical assault. We therefore decided to record atten...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/0956462991912926
更新日期:1999-01-01 00:00:00
abstract:AIMS:To identify any differences in follow-up rates or sexual contact attendance rates in men presenting with non-gonococcal urethritis (NGU) after treatment by single dose azithromycin rather than longer standard duration therapies and to identify patients' treatment preferences. METHODS:A prospective study was perfo...
journal_title:International journal of STD & AIDS
pub_type: 临床试验,杂志文章
doi:10.1258/0956462961917591
更新日期:1996-05-01 00:00:00
abstract::The prompt and effective treatment of pelvic inflammatory disease (PID) may reduce the risk of complications such as infertility, ectopic pregnancy and pelvic pain. We conducted a national audit to investigate the treatment of women diagnosed with PID and associated rates of partner notification in genitourinary (GU) ...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/ijsa.2011.011183
更新日期:2012-01-01 00:00:00
abstract::The aim of this study was to analyse in a large sample of HIV-infected subjects the expectations toward complementary therapies (CT) and the characteristics of users. Self-administered anonymous questionnaires were distributed in seven European countries among HIV-infected subjects consecutively attending the offices ...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/095646203322025803
更新日期:2003-07-01 00:00:00
abstract::Women who have a prevention mindset may opt for concurrent use of oral pre-exposure prophylaxis (PrEP) and all forms of contraception; we therefore assessed how contraception may influence PrEP use or vice versa. We analyzed data from Kenyan and Ugandan HIV-uninfected non-pregnant women in sero-discordant partnerships...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/0956462420951501
更新日期:2020-11-01 00:00:00
abstract::HIV testing and counselling is crucial in identifying new HIV cases and linking them to treatment. Provider-initiated testing and counselling can help to increase uptake of HIV testing and counselling and HIV case detection. We implemented provider-initiated testing and counselling in 32 health facilities in Ebonyi St...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/0956462418783533
更新日期:2018-12-01 00:00:00
abstract::Late HIV diagnosis in the UK remains a major cause of morbidity and mortality. In line with British HIV Association recommendations, we implemented routine HIV Screening in Croydon University Hospital Acute Medical Unit in London after an audit in 2011 revealed very high levels of late diagnosis. Our re-audit assessed...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/0956462415597346
更新日期:2016-06-01 00:00:00
abstract::Our objective was to explore the epidemiology of HIV and syphilis at population level in young Chinese adults. The study was carried out in six areas of three Chinese provinces: Zhejiang, Yunnan and Shaanxi. All couples attending the compulsory premarital examination were recruited. Routinely taken blood was collected...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/0956462053420257
更新日期:2005-03-01 00:00:00
abstract::Reducing the number of sex partners and using condoms are the major means for individuals to protect themselves from STDs and AIDS in sub-Saharan Africa. To identify predictors of having only one sex partner in the last year and to assess knowledge and use of condoms among women of reproductive age in Dar-es-Salaam, T...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/095646249500600307
更新日期:1995-05-01 00:00:00
abstract::Lactobacillus sp. are commensal organisms that are increasingly reported to cause invasive infections among immunosuppressed persons. However, few data exist regarding the occurrence and risk factors of these infections among HIV-infected persons. Further, the safety of products that contain lactobacilli (e.g. probiot...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章,评审
doi:10.1177/0956462415590725
更新日期:2016-11-01 00:00:00
abstract::This cross-sectional study explored the prevalence and correlates of syphilis infection among people who use and inject drugs (PWUD/PWID) in Cambodia. Data were collected in 2017 from 1,677 PWUD/PWID living in the capital city of Phnom Penh and 11 other major provinces using the respondent-driven sampling method. The ...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/0956462420929132
更新日期:2020-08-01 00:00:00
abstract::Few analytic opportunities have allowed us to evaluate the role that specific sexual acts and male latex condoms play in the acquisition of external anal warts (EAW) using longitudinal data. The acquisition of EAWs occurs from epithelial contact with other HPV-infected surfaces, and hence is dependent upon sexual beha...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章,多中心研究
doi:10.1258/0956462053420176
更新日期:2005-03-01 00:00:00
abstract::The 'dynias' are a group of chronic focal pain syndromes with a predilection for orocervical or urogenital regions. Only exceptionally do they involve both sites in the same patient. Here, we report a case of simultaneous occurrence of dysaesthetic peno/scroto dynia and stomatodynia. ...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/095646205774988154
更新日期:2005-12-01 00:00:00
abstract::The aim of the work is to describe the occurrence of ocular complications and loss of vision due to herpes zoster ophthalmicus (HZO) in HIV-positive patients who received early antiviral therapy for HZO.This is a post hoc analysis of prospectively collected data.Twenty-four HIV-positive patients with HZO were included...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/0956462412472303
更新日期:2013-02-01 00:00:00
abstract::We assessed the validity of self-reported sex and condom use by comparing self-reports with prostate-specific antigen (PSA) detection in a prospective study of 210 female sex workers in Mombasa, Kenya. Participants were interviewed on recent sexual behaviours at baseline and 12-month follow-up visits. At both visits, ...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/095646207779949899
更新日期:2007-01-01 00:00:00
abstract::HIV-1 and HSV-2 are frequent genital co-infections in women. To determine how self-collected genital swabs compare to provider-collected cervicovaginal lavage, paired self-collected genital swabs and cervicovaginal lavage from women co-infected with HIV-1 and HSV-2 were evaluated. Women were in an acyclovir clinical t...
journal_title:International journal of STD & AIDS
pub_type: 临床试验,杂志文章
doi:10.1177/0956462416650123
更新日期:2017-03-01 00:00:00
abstract::We examined health-care seeking practices among patients with sexually transmitted diseases (STDs) in south China. In 1995, we recruited a consecutive sample of 939 STD patients attending the STD clinics of the Municipal STD Control Centers of Guangzhou and Shenzhen, 'special economic zones' near Hong Kong. Attending ...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/0956462991914177
更新日期:1999-05-01 00:00:00
abstract::Rising heterosexual syphilis in south London in 2002 prompted Local Enhanced Syphilis Surveillance (LESS) in five of the 10 genitourinary medicine clinics. LESS reported a fall in heterosexual infectious syphilis in 2004 that was corroborated by the National Enhanced Syphilis Surveillance (NESS). However, mandatory cl...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/ijsa.2008.008216
更新日期:2009-03-01 00:00:00