Abstract：
:Women who have a prevention mindset may opt for concurrent use of oral pre-exposure prophylaxis (PrEP) and all forms of contraception; we therefore assessed how contraception may influence PrEP use or vice versa. We analyzed data from Kenyan and Ugandan HIV-uninfected non-pregnant women in sero-discordant partnerships who were participating in the Partners Demonstration Project. Using multivariable generalized estimating equation models, we estimated the associations between effective contraceptive use and 1) PrEP dispensation 2) high effective PrEP use. Among the 311 women (93.1% of all those followed in the Partners Demonstration Project) median age was 29 years (interquartile range [IQR] 24.0-35.0) and 115 (37.0%) reported using effective contraception at baseline. All the women initiated PrEP during the study and moderately high PrEP adherence was recorded at 73.1% of visits over an average 7.5 months following PrEP dispensation. Women (14.8%) consistently used an effective contraceptive throughout study follow-up. PrEP dispensation was more frequent among those concurrently using effective contraception, (adjusted relative risk [aRR] = 1.19; 95% confidence interval [CI] = 1.08-1.32) and contraceptive use was more common among those on PrEP (aRR = 1.63; 95% CI = 1.18-2.25). Among East African women at high risk of HIV infection, PrEP dispensation was more frequent among women using effective contraception, indicating that family planning outlets may be efficient locations to deliver PrEP.
journal_name
Int J STD AIDSjournal_title
International journal of STD & AIDSauthors
Ngure K,Velloza J,Patel RC,Mugo NR,Bukusi EA,Haberer JE,Odoyo J,Celum C,Baeten JM,Heffron Rdoi
10.1177/0956462420951501subject
Has Abstractpub_date
2020-11-01 00:00:00pages
1263-1271issue
13eissn
0956-4624issn
1758-1052journal_volume
31pub_type
杂志文章abstract：:The aim of this revision is to evaluate ethnicity and gender rate of enrolment in registrative clinical trials of the protease inhibitors (Pls) from 1996 to 2009. Company-sponsored, phase II or III registrative clinical trials of PIs were evaluated. Forty-nine clinical trials were included. Clinical trials were conduc...
journal_title：International journal of STD & AIDS
pub_type： 杂志文章,评审
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abstract：:A vaginal tampon specimen was previously shown to be suitable for the molecular diagnosis of non-ulcerative sexually transmitted infections (STIs). Different tampon fluid preparations were evaluated for the diagnosis of bacterial vaginosis (BV). Women with pregnancy related problems were enrolled. Two observers evalua...
journal_title：International journal of STD & AIDS
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journal_title：International journal of STD & AIDS
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journal_title：International journal of STD & AIDS
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journal_title：International journal of STD & AIDS
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journal_title：International journal of STD & AIDS
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journal_title：International journal of STD & AIDS
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journal_title：International journal of STD & AIDS
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journal_title：International journal of STD & AIDS
pub_type： 杂志文章,评审
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journal_title：International journal of STD & AIDS
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journal_title：International journal of STD & AIDS
pub_type： 杂志文章
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journal_title：International journal of STD & AIDS
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更新日期：2006-02-01 00:00:00
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journal_title：International journal of STD & AIDS
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journal_title：International journal of STD & AIDS
pub_type： 杂志文章
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journal_title：International journal of STD & AIDS
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journal_title：International journal of STD & AIDS
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