Abstract:
:We compared HIV-1 RNA levels using the nucleic acid sequenced based amplification (NASBA) test kit in 2 samples taken one year apart from participants infected with env subtype A or D in a population-based cohort in Uganda. Fifty participants were infected with subtype A and 70 with subtype D. HIV-1 RNA levels were significantly higher in subtype D unadjusted (P=0.001), and after adjusting for age, gender, and CD4 count (P<0.001). Eighty-six participants had HIV-1 RNA measurements in both years and 67 (78%) were within one log10 of their result a year before. There was no relationship between the difference in log viral load and proportion of CD4 change. Individuals infected with subtype D had a higher average increase in viral load and this was statistically significant if adjusted for baseline levels and CD4 count (P=0.015).
journal_name
Int J STD AIDSjournal_title
International journal of STD & AIDSauthors
Morgan D,Kaleebu P,Whitworth J,Yirrell D,Rutebemberwa A,Shier R,Sebabi B,Gilmour J,Eotu H,Omoding N,Gotch Fdoi
10.1258/0956462011916758subject
Has Abstractpub_date
2001-02-01 00:00:00pages
116-21issue
2eissn
0956-4624issn
1758-1052journal_volume
12pub_type
杂志文章abstract::Reducing the number of sex partners and using condoms are the major means for individuals to protect themselves from STDs and AIDS in sub-Saharan Africa. To identify predictors of having only one sex partner in the last year and to assess knowledge and use of condoms among women of reproductive age in Dar-es-Salaam, T...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/095646249500600307
更新日期:1995-05-01 00:00:00
abstract::The purpose of this study was to quantify the impact of recurrent genital herpes (RGH) on health-related quality of life, healthcare resource and workplace productivity. This was a cross-sectional survey conducted in 5 countries (Australia, Denmark, Italy, The Netherlands and UK). Patients with a confirmed history of ...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/0956462011923859
更新日期:2001-10-01 00:00:00
abstract::The aetiology of chronic prostatitis is poorly understood. A cross-sectional study of a population of male undergraduates in Nigeria, using a questionnaire containing the National Institutes of Health Chronic Prostatitis Symptom Index (NIH-CPSI) and some other relevant sex-related questions, was conducted. A total of ...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/ijsa.2010.010317
更新日期:2011-02-01 00:00:00
abstract::The incidence of anogenital warts (condyloma acuminatum) is rapidly increasing while there is still no totally satisfactory treatment available. In light of the emphasis of experimental approaches toward the prevention of viral replication and evidence of the antiviral action of lithium salts it was proposed to invest...
journal_title:International journal of STD & AIDS
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1258/0956462971920677
更新日期:1997-08-01 00:00:00
abstract::Safer conception strategies to reduce the HIV transmission risk include antiretroviral therapy for HIV-positive partners, pre-exposure prophylaxis for HIV-negative partners, condomless sex limited to fertile periods, and home-based self-insemination. Resistance to taking treatment or cultural concerns may limit uptake...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/0956462415604091
更新日期:2016-10-01 00:00:00
abstract::HIV serodisclosure to sexual partners is an important aspect of HIV prevention, treatment, and care. We investigated the association between partnership duration and serodisclosure among HIV-infected individuals in Lilongwe, Malawi. We analyzed data from a cross-sectional study of individuals attending one of two anti...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/0956462418769730
更新日期:2018-09-01 00:00:00
abstract::Increasing numbers of HIV-infected children are now reaching adulthood and young people account for 10% of new HIV diagnosis in the UK each year. This audit of young people attending specialist and generic HIV services in Inner London in 2006 (n=39) highlights the complex medical and psychosocial needs of this patient...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/095646207781568565
更新日期:2007-09-01 00:00:00
abstract::HIV seroconversions and sexually transmitted diseases (STDs) are often clustered in social networks within community populations. The present study was carried out among men who have sex with men in Russia, where a major HIV epidemic is unfolding, and where social networks have played a historically important role. In...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/095646206775220504
更新日期:2006-01-01 00:00:00
abstract::It is a commonly expressed expert view that stress is associated with frequent recurrences of genital herpes (GH) but the evidence for this is poor and it is often asserted that stress is the result of GH rather than any other cause. We have reviewed the recent literature on this topic, restricting evidence to only pr...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章,评审
doi:10.1258/ijsa.2007.007304
更新日期:2008-06-01 00:00:00
abstract::Renal transplant recipients represent a patient subgroup for whom the effective treatment of genital warts poses a significant problem in genitourinary medicine. This case demonstrates the safe and effective treatment of resistant perianal warts in a male renal transplant recipient using imiquimod. ...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/0956462021925180
更新日期:2002-05-01 00:00:00
abstract::We assessed the validity of a syndromic case management approach for reproductive tract infections (RTIs) among 371 pregnant women attending antenatal care facilities in Kingston, Jamaica, using an algorithm previously validated in high-risk Jamaican women. For our antenatal attenders, the algorithm had low sensitivit...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/095646204774195209
更新日期:2004-06-01 00:00:00
abstract::Paradoxical reactions, including immune reconstitution inflammatory syndrome (IRIS), are common in patients co-infected with human immunodeficiency virus (HIV) and tuberculosis (TB). Paradoxical reactions may confer substantial morbidity and mortality, especially in cases of central nervous system (CNS) TB, or through...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/0956462420915394
更新日期:2020-07-01 00:00:00
abstract::Few analytic opportunities have allowed us to evaluate the role that specific sexual acts and male latex condoms play in the acquisition of external anal warts (EAW) using longitudinal data. The acquisition of EAWs occurs from epithelial contact with other HPV-infected surfaces, and hence is dependent upon sexual beha...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章,多中心研究
doi:10.1258/0956462053420176
更新日期:2005-03-01 00:00:00
abstract::A 21-year-old man presented to genitourinary (GU) medicine physicians with (initially) painful penile and scrotal swelling. A diagnosis of ano-genital granulomatosis was confirmed on histological analysis of penile skin. Enquiring about systemic symptoms resulted in the additional diagnosis of gastrointestinal Crohn's...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/ijsa.2012.012183
更新日期:2013-02-01 00:00:00
abstract::Local genital tract inflammation stimulates leukocyte activity and causes HIV shedding, potentially increasing HIV sexual infectiousness. Although there are available clinical markers for genital tract inflammation, such as urinary leukocyte esterase, none have yet been examined in relation to HIV sexual risk behaviou...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/0956462414536147
更新日期:2015-04-01 00:00:00
abstract::The aim of this study was to investigate the factors relating to CD4 level at HIV diagnosis and HIV testing behaviour. Participants were newly diagnosed patients (n = 654) in Japan from 2000 to 2005. Around 75% of participants were diagnosed at hospital and clinics. Mean CD4 counts at diagnosis through voluntary HIV t...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/ijsa.2009.009493
更新日期:2012-04-01 00:00:00
abstract::Self-inserted vaginal tampons for the molecular diagnosis of non-ulcerative STIs were evaluated. Cervical and vaginal swabs, tampons and urines were collected from 185 first-time antenatal clinic attendees. Cultures and nucleic acid amplification assays (NAA) were performed. The sensitivity of PCR on tampons for Trich...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/095646204322764271
更新日期:2004-02-01 00:00:00
abstract::We characterized HIV-1 subtypes among 204 persons newly diagnosed with HIV in Ontario from 2003 to 2005 using samples from the Canadian HIV Strain and Drug Resistance Surveillance Program. We examined HIV-1 subtype by demographic characteristics and exposure category, and determined independent predictors of infection...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/ijsa.2009.009303
更新日期:2012-10-01 00:00:00
abstract::National guidelines state that hepatitis B and C testing should be targeted to those with risk factors. However, there is little data to support this recommendation. There is also limited data of viral hepatitis prevalence in attendees at genitourinary medicine clinics. We report the prevalence of hepatitis B infectio...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/0956462416641528
更新日期:2017-03-01 00:00:00
abstract::Limited data exist on hepatitis B revaccination strategies for HIV-infected individuals who do not develop immunity after the first vaccination series. A retrospective cohort study was conducted to assess the immunogenicity of the second series of hepatitis B vaccine given in standard dosing (SD) and double dosing (DD...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/0956462415596498
更新日期:2016-09-01 00:00:00
abstract::A cross-sectional study of 360 patients presenting with sexually transmitted diseases (STDs) to a primary care clinic in KwaZulu/Natal, South Africa was done. Prevalence of HIV infection was 42.5%. HIV-infected patients were of similar age to uninfected patients (mean age 25.1 vs 26.1 years), but were less likely to b...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/0956462981921486
更新日期:1998-12-01 00:00:00
abstract::This study employed culture and polymerase chain reaction (PCR) to examine the prevalence of Ureaplasma urealyticum, Mycoplasma hominis, Mycoplasma genitalium, Mycoplasma fermentans, Mycoplasma penetrans and Mycoplasma pirum in 210 HIV/AIDS patients, 455 sexually transmitted infection (STI) clinic attendees and 245 he...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/ijsa.2009.009396
更新日期:2012-08-01 00:00:00
abstract::Patients who do not attend (DNA) clinic appointments are wasteful of resources and may also pose a potential public health risk through the onward transmission of untreated sexually transmitted infections (STIs). This service evaluation was performed to assess the demographics of DNAs, patient reasons for non-attendan...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/ijsa.2009.009349
更新日期:2010-05-01 00:00:00
abstract::To determine the frequency, imaging characteristics, neuroanatomical distribution and dynamics of magnetic resonance imaging findings in HIV-associated cryptococcal meningitis in immunocompromised patients we compared patients without antiretroviral therapy with patients undergoing immune reconstitution. Neuroimaging ...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/0956462415574633
更新日期:2016-02-01 00:00:00
abstract::We report a case of acute epididymo-orchitis due to early infectious syphilis, mimicking as testicular malignancy in an undiagnosed HIV-positive individual. He presented with a mass on his testicle and simultaneously had serology consistent with early syphilis. It could not be distinguished from a malignancy, which ne...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/ijsa.2008.008253
更新日期:2009-01-01 00:00:00
abstract::We examined health-care seeking practices among patients with sexually transmitted diseases (STDs) in south China. In 1995, we recruited a consecutive sample of 939 STD patients attending the STD clinics of the Municipal STD Control Centers of Guangzhou and Shenzhen, 'special economic zones' near Hong Kong. Attending ...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/0956462991914177
更新日期:1999-05-01 00:00:00
abstract::A questionnaire survey and case notes audit reviewing management of epididymo-orchitis (E-O) by 34 Genitourinary Medicine (GUM) clinics located in the North Thames was undertaken. Twenty-two clinics (65%) returned completed questionnaires and audited a total of 83 newly diagnosed cases. All participating clinics offer...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/0956462011923066
更新日期:2001-05-01 00:00:00
abstract::The British HIV Association (BHIVA) has published guidelines for immunization of HIV-infected adults. A chart review of 200 HIV-infected patients diagnosed was conducted to determine shortcomings in previous practice and determine which vaccines should routinely be given in specialist HIV clinics and which might be ab...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/ijsa.2011.011231
更新日期:2012-02-01 00:00:00
abstract::Previous research conducted to examine the implications of using audio-computerized (A-CASI) procedures to gather sensitive sexual behaviour data has provided mixed results. The purpose of this study was to assess differences in the disclosure of HIV risk behaviours between subjects interviewed face to face and subjec...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/095646202320753754
更新日期:2002-11-01 00:00:00
abstract::We describe the first reported case of Candida pelliculosa meningitis in HIV infection. This case highlights the risk of uncommon opportunistic infections in association with the immunocompromised and the importance of autopsy as a diagnostic tool in HIV infection. We discuss the epidemiology, diagnosis and management...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/ijsa.2010.010113
更新日期:2011-01-01 00:00:00