Abstract:
:The purpose of this study was to quantify the impact of recurrent genital herpes (RGH) on health-related quality of life, healthcare resource and workplace productivity. This was a cross-sectional survey conducted in 5 countries (Australia, Denmark, Italy, The Netherlands and UK). Patients with a confirmed history of RGH completed the MOS 36-Item Short Form Health Survey (SF-36) and the Recurrent Genital Herpes Quality of Life questionnaire (RGHQoL). Questionnaires addressing frequency of access to healthcare services and workplace productivity were also completed and patients' medical history was obtained. Scores for 6 of the 8 domains of the SF-36 were significantly lower (P<0.001) i.e. worse, compared with scores for the normal population. The RGHQoL score was significantly lower in patients experiencing more frequent or more severe recurrences. Forty-five per cent of patients estimated that their work effectiveness was reduced by between 25% and 50% due to genital herpes symptoms.
journal_name
Int J STD AIDSjournal_title
International journal of STD & AIDSauthors
Patel R,Boselli F,Cairo I,Barnett G,Price M,Wulf HCdoi
10.1258/0956462011923859subject
Has Abstractpub_date
2001-10-01 00:00:00pages
640-5issue
10eissn
0956-4624issn
1758-1052journal_volume
12pub_type
杂志文章abstract::HIV serodisclosure to sexual partners is an important aspect of HIV prevention, treatment, and care. We investigated the association between partnership duration and serodisclosure among HIV-infected individuals in Lilongwe, Malawi. We analyzed data from a cross-sectional study of individuals attending one of two anti...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/0956462418769730
更新日期:2018-09-01 00:00:00
abstract::Raltegravir is one of the standard antiretroviral therapy (ART) options in treatment-experienced and -naïve patients. However, efficacy data from clinical practice are scarce. Therefore, the efficacy of raltegravir-containing ART in clinical practice was investigated retrospectively. In all, 295 treatment-naïve and -e...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/0956462415610678
更新日期:2016-11-01 00:00:00
abstract::The incidence of disseminated Mycobacterium avium complex (MAC) infection in HIV patients has fallen markedly since the introduction of effective antiretroviral therapy (ART). However, current guidelines still recommend primary prophylaxis. We conducted a retrospective cohort study in a university-affiliated hospital ...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/0956462417713432
更新日期:2017-12-01 00:00:00
abstract::The purpose of this paper is to assess the internal consistency of self-reported condom use among sex workers in Puerto Plata and Santo Domingo, Dominican Republic. We examined the responses to questions about condom use among 4 cross-sectional samples of sex workers. We compared measures based on: (1) questions using...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/0956462981922089
更新日期:1998-04-01 00:00:00
abstract::The main purpose of this study was to investigate how loneliness was associated with social support and family function among people living with HIV/AIDS (PLWHA) in an HIV-stricken area of China. Two hundred and nineteen PLWHA were surveyed using the UCLA (University of California at Los Angeles)-Loneliness Scale, the...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/ijsa.2008.008348
更新日期:2009-04-01 00:00:00
abstract::In 1987, data from the Centers for Disease Control AIDS data base indicated a 50% prevalence of oropharyngeal Candida infection, a 10% rate of esophageal infection, and .5% rate of bronchopulmonary infection among AIDS patients. Candida-positive blood cultures were found in 13 of 903 AIDS patients, and disseminated C...
journal_title:International journal of STD & AIDS
pub_type: 社论
doi:10.1177/095646249200300301
更新日期:1992-05-01 00:00:00
abstract::Pancreatic neuroendocrine tumours (PETs), though rare, are usually slow growing tumours with a relatively good prognosis. We describe a case of an aggressive malignant neuroendocrine tumour of the pancreas occurring in an AIDS patient, which has not been reported previously. ...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/0956462011922841
更新日期:2001-04-01 00:00:00
abstract::The Department of Health has addressed access to genitourinary medicine services by setting targets that 100% of patients should be offered an appointment within 48 hours of contact and 95% should be seen within 48 hours. Such rapid access appointments are often declined by patients. We wished to ascertain whether pat...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/ijsa.2008.008513
更新日期:2009-09-01 00:00:00
abstract::The pharmacokinetics of antiretroviral drugs in pregnancy is poorly understood. We reviewed the use of therapeutic drug monitoring (TDM) in clinical settings to document plasma concentrations of lopinavir during pregnancy and investigated how clinicians acted upon TDM results. A retrospective review was carried out of...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/ijsa.2009.009184
更新日期:2011-01-01 00:00:00
abstract::In the genitourinary medicine clinic setting, the most practical and widely used method of diagnosing Trichomonas vaginalis (TV) is direct microscopy of a wet mount preparation (WMP) of a sample taken from the posterior vaginal fornix. We retrospectively reviewed the potential impact of further limiting WMP to women w...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/095646207781024892
更新日期:2007-06-01 00:00:00
abstract::Increasing numbers of HIV-infected children are now reaching adulthood and young people account for 10% of new HIV diagnosis in the UK each year. This audit of young people attending specialist and generic HIV services in Inner London in 2006 (n=39) highlights the complex medical and psychosocial needs of this patient...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/095646207781568565
更新日期:2007-09-01 00:00:00
abstract::Psoriasis is a prevalent systemic immune-mediated disease with cutaneous manifestations. In HIV-infected patients, psoriasis may have a higher incidence, present atypical and more exuberant clinical features, and is frequently recalcitrant to treatment. Despite this aggravated severity, treatment options for psoriasis...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章,评审
doi:10.1177/0956462419827673
更新日期:2019-05-01 00:00:00
abstract::Sweden was the first country to introduce online Chlamydia trachomatis testing for both men and women and this article provides information about the user characteristics and which risk groups are reached with this method. During the years 2005-2007 a questionnaire was administered with a response rate of 86% (n = 602...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/ijsa.2011.011030
更新日期:2012-02-01 00:00:00
abstract::In a study to determine the significance of Bacteroides ureolyticus in the lower urogenital tract using a new selective and differential medium, this organism was isolated from 30.1% of asymptomatic men, 37.8% of men with genital warts, and 26.3% of men with non-gonococcal urethritis. Using the same selective medium B...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/095646249200300206
更新日期:1992-03-01 00:00:00
abstract::Fusarium infections are very rare in HIV-infected patients, even in patients in advanced stages of immunosuppression. All the reported cases in the literature are of disseminated infection, and with poor outcomes despite prompt and appropriate treatment. To the best of our knowledge, this is the first report of a loca...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/0956462418761259
更新日期:2018-09-01 00:00:00
abstract::With the increasing incidence of chronic kidney disease in patients with human immunodeficiency virus (HIV), the number of HIV-infected patients requiring hemodialysis has also increased. Dolutegravir is an integrase inhibitor that is a common component of HIV treatment regimens. Currently, there is no guidance regard...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/0956462418816785
更新日期:2019-05-01 00:00:00
abstract::The aim of this study was to assess prevalence and risk factors for sexually transmitted infections (STIs) among fishermen along Lake Victoria, Kenya. This cross-sectional study surveyed 250 fishermen from beaches in Kisumu District using proportional-to-size sampling based on the number of registered boats per beach....
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/ijsa.2010.010160
更新日期:2010-10-01 00:00:00
abstract::This is the case of a black African woman who presented with three distinct episodes of herpes simplex virus (HSV) infection unresponsive to first-line therapy. Clinical and virological resistance to aciclovir therapy was demonstrated, and although the first two episodes manifested as the deep ulceration often associa...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/095646207780132361
更新日期:2007-03-01 00:00:00
abstract::Sweet's syndrome is a rare skin condition associated with both drug treatment and a number of different disease processes including haematological malignancies, inflammatory conditions and HIV infection. In this case report, we present a patient with HIV, haemophilia and hepatitis C who presented to our team with sign...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/ijsa.2009.009314
更新日期:2012-06-01 00:00:00
abstract::Current teaching on Reiter's syndrome is that keratoderma blennorrhagica lesions appear characteristically on the soles of feet, although they can be seen on other parts of the body infrequently. We therefore thought that it would be interesting to report the case of keratoderma blennorrhagica lesions found on the gla...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/0956462021924631
更新日期:2002-02-01 00:00:00
abstract::In the ARTEMIS trial, 689 treatment-naïve, HIV-1-infected adults received darunavir/ritonavir (DRV/r) 800/100 mg every day or lopinavir/ritonavir (LPV/r) 800/200 mg total daily dose plus fixed-dose tenofovir/emtricitabine. Week 96 metabolic parameters are reported. Adverse events (AEs) classed as metabolism/nutrition ...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章,随机对照试验
doi:10.1258/ijsa.2012.012120
更新日期:2013-01-01 00:00:00
abstract::To assess the efficacy of a novel glycosylated mammalian cell derived recombinant human interferon-beta (r-hIFN-beta-1a) in the intralesional treatment of genital condylomata acuminata. The study was randomized, double-blind and placebo-controlled. Patients (n=60) with up to 8 distinct condylomata acuminata were rando...
journal_title:International journal of STD & AIDS
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1258/0956462971918878
更新日期:1997-10-01 00:00:00
abstract::A longitudinal study of demographic and behavioural characteristics associated with risky sexual behaviours of young men after release from prison. One hundred and six men were interviewed in prison and at one week and six months after release. Overall, 37% reported a previous sexually transmitted disease (STD) diagno...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/095646203767869110
更新日期:2003-08-01 00:00:00
abstract::Lactobacillus sp. are commensal organisms that are increasingly reported to cause invasive infections among immunosuppressed persons. However, few data exist regarding the occurrence and risk factors of these infections among HIV-infected persons. Further, the safety of products that contain lactobacilli (e.g. probiot...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章,评审
doi:10.1177/0956462415590725
更新日期:2016-11-01 00:00:00
abstract::Reducing the number of sex partners and using condoms are the major means for individuals to protect themselves from STDs and AIDS in sub-Saharan Africa. To identify predictors of having only one sex partner in the last year and to assess knowledge and use of condoms among women of reproductive age in Dar-es-Salaam, T...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/095646249500600307
更新日期:1995-05-01 00:00:00
abstract::The management and outcome of all cases of gonorrhoea which presented to a south London genitourinary medicine clinic during 1999 were assessed and compared with published national guidelines. The incidence of penicillin resistance was calculated, as was the rate of co-infection with chlamydia and trichomonas. Informa...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/095646203322301095
更新日期:2003-09-01 00:00:00
abstract::Patients who acquire repeated infections of gonorrhoea are well described. A study was undertaken of male patients attending a central London clinic in an attempt to identify features of those acquiring repeated infections to facilitate risk reduction strategies. During the 3 years 1990 to 1992, 18.8% of patients cont...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/0956462961917807
更新日期:1996-07-01 00:00:00
abstract::A 48-year-old woman with HIV infection developed Cushingoid features while she was taking ritonavir-boosted darunavir. Cushing's syndrome was confirmed due to the drug interaction between ritonavir and budesonide. Diagnosis of iatrogenic Cushing's syndrome in HIV-positive patients who are on ritonavir-boosted protease...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/ijsa.2011.011408
更新日期:2012-07-01 00:00:00
abstract::We report a case of human herpes virus-8-associated multicentric Castleman's disease in an HIV-positive patient with hyponatraemia. A 65-year-old man was admitted with relapsing and remitting fever, scattered skin eruptions and hepatosplenomegaly following combination antiretroviral therapy for his HIV infection. Base...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/0956462414562050
更新日期:2015-10-01 00:00:00
abstract::In Jamaica, where homosexuality is criminalized, scant research has examined associations between sexual stigma and HIV infection. The study objective was to examine correlates of HIV infection among men who have sex with men (MSM) in Jamaica. We conducted a cross-sectional tablet-based survey with MSM in Jamaica usin...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/0956462417717652
更新日期:2018-01-01 00:00:00