Lack of behavioural risk factors for squamous intraepithelial lesions (SIL) in HIV-infected women.

Abstract:

:HIV-infected women have a high prevalence of abnormal Papanicolaou smears and cervical intraepithelial neoplasia. A multiparametric analysis of epidemiological and behavioural risk factors has been performed in a cohort of 204 HIV-infected women in an outpatient clinic with the aim to investigate risk factors associated with squamous intraepithelial lesions (SIL) in HIV-seropositive women. The prevalence of SIL in the study population was 35.7%. Univariate and multivariate analysis of demographic, behavioural and immunological variables only identified cigarette smoking > 20/day and CD4+ cell counts < or = 200 x 10(6)/L as risk factors significantly associated with SIL in the study population. We found no epidemiological/behavioural risk factors specifically associated with SIL in HIV-infected women as compared with the general population. The results suggest that the high prevalence of SIL in HIV disease is related to acquired immune deficiency in HIV-seropositive women.

journal_name

Int J STD AIDS

authors

Heard I,Jeannel D,Bergeron C,Saada M,Henrion R,Kazatchkine MD

doi

10.1258/0956462971920316

subject

Has Abstract

pub_date

1997-06-01 00:00:00

pages

388-92

issue

6

eissn

0956-4624

issn

1758-1052

journal_volume

8

pub_type

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