Abstract:
:Individuals diagnosed with HIV before 1996 had poor prognoses. Few HIV care centers can track patients continuously from the 1980s to present. We determined the sociodemographic, clinical, and health care utilization characteristics of patients diagnosed and followed for >20 years (i.e. long-term HIV/AIDS survivors) to understand what factors contributed to survival. All HIV-positive patients diagnosed before 1996 were categorized as active, moved/lost, or died as of 1 January 2016. Baseline sociodemographic, clinical characteristics, antiretroviral therapy (ART) usage, retention, HIV care costs, and health status were analyzed. Of 876 patients, 49.5% died, 30.3% moved or left, 20.3% remained active in care for a median of 23.4 years. At diagnosis, continuously-followed patients were younger with a higher CD4 cell count, attended regular clinic visits at higher frequencies, and had received more ART than patients who moved or died. As of 1 January 2016, their median age was 57 years (interquartile range 53-62), 15% were aged >65 years, median CD4 cell count was 591 cells/mm3 (475-863) with 68% >500 cells/mm3. Sixty-two percent remained employed. The total cost of HIV care was $32,251,030 (Cdn$); median cost per patient per year $15,418 ($13,697-$18,392). Individuals diagnosed prior to 1996 benefited from early diagnosis and engagement to care, regular follow-ups, and timely initiation of ART, strongly supporting the modern guidelines of care.
journal_name
Int J STD AIDSjournal_title
International journal of STD & AIDSauthors
Krentz HB,John Gill Mdoi
10.1177/0956462418778705subject
Has Abstractpub_date
2018-11-01 00:00:00pages
1098-1105issue
11eissn
0956-4624issn
1758-1052journal_volume
29pub_type
杂志文章abstract::In Bambari and Bria, 2 towns in the Central African Republic (CAR), we analysed a patient-led partner referral programme within enhanced sexually transmitted disease (STD) services. New (index) patients received syndromic management, counselling about notifying and treating contacts, and vouchers for distribution. Fro...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:
更新日期:1999-06-01 00:00:00
abstract::The copper intrauterine contraceptive device (IUCD) is strongly associated with bacterial vaginosis (BV). Hormonal influences may play a role in the control of vaginal flora. It is unclear whether use of the progesterone-incorporated intrauterine system (IUS; Mirena) is associated with abnormal vaginal flora or genita...
journal_title:International journal of STD & AIDS
pub_type: 临床试验,杂志文章
doi:10.1258/ijsa.2008.008391
更新日期:2009-06-01 00:00:00
abstract::There are few data on the impact of antiretroviral therapy (ART) regimen factors on adherence in ART-naïve HIV patients on contemporary once- or twice-daily regimens. Ninety-nine newly diagnosed patients in a prospective observational cohort study completed a visual analogue scale to assess their ART adherence. Adhere...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/ijsa.2011.011292
更新日期:2012-05-01 00:00:00
abstract::Sexual functioning is often neglected in the care of HIV-infected patients. Little information exists about the relationship between hormonal factors, psychological factors, medication, HIV disease stage and sexual functioning among persons with HIV disease. In this study, 50 HIV+ men completed the Derogatis Sexual Fu...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/0956462981921332
更新日期:1998-11-01 00:00:00
abstract::Primary HIV can be asymptomatic or result in a severe symptomatic illness. Common symptoms are pyrexia, pharyngitis, malaise, lethargy, maculopapular rash, mucous membrane ulceration, lymphadenopathy and headache. It can be reliably diagnosed by a positive virologic test in the absence of HIV-specific antibodies. Prog...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章,评审
doi:10.1258/0956462021924613
更新日期:2002-02-01 00:00:00
abstract::UK post-exposure prophylaxis (PEP) guidelines were updated by the British Association for Sexual Health and HIV (BASHH) in 2011. In 2013, we changed policy to omit day 5 PEP follow-up at 56 Dean Street as it was felt clinically unnecessary. This audit compares our performance against BASHH standards for PEP attenders ...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/0956462414547090
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abstract::Chlamydia trachomatis and Neisseria gonorrhoeae testing guidance recommends extragenital screening with locally validated nucleic acid amplification tests, with anatomical sites tested separately. Evidence supports multi-patient combined aliquot pooled sampling (PS) for population screening; evidence for within-patien...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/0956462417742318
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abstract::We examined treatment-seeking behaviours amongst a consecutive sample of 188 first-time attenders at a busy genitourinary (GU) clinic in a general hospital. Participants were interviewed and completed a battery of questionnaires prior to receiving diagnosis or treatment. Delay in treatment seeking was measured in 3 wa...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/0956462001916083
更新日期:2000-06-01 00:00:00
abstract::The two major risk groups for acquisition of HIV in the UK are gay men and IDUs. Individuals from these risk groups vary in a number of respects in their life-style, which have the potential to affect the course of their HIV disease. This study compares gay men and IDUs from the Lothian Region of Scotland with respect...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/095646249400500608
更新日期:1994-11-01 00:00:00
abstract::The objectives of the study were, 1. To ascertain if sexual health physicians and practitioners believe a question concerning a past history of non-consensual sex should be asked routinely and are asking it. 2. To identify whether sexual health services have established protocols to integrate this question into practi...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/095646203321605530
更新日期:2003-05-01 00:00:00
abstract::This study of sexual behaviour in the city of Lisbon is based on data obtained from 2 random samples, one of individuals aged 16-20 (n = 400) and another of individuals over the age of 20 (n = 400). Samples have been stratified by district, gender and age. Data were obtained by personal interview and by questionnaires...
journal_title:International journal of STD & AIDS
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1177/095646249500600108
更新日期:1995-01-01 00:00:00
abstract::The primary aim of the current study was to test the effect of the presentation design of a test alert system on healthcare workers' (HCWs') decision-making regarding blood-borne virus (BBV) testing. The secondary aim was to determine HCWs' acceptance of the system. An online survey used a within-subjects research des...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/0956462420906998
更新日期:2020-07-01 00:00:00
abstract::Psoriasis is a prevalent systemic immune-mediated disease with cutaneous manifestations. In HIV-infected patients, psoriasis may have a higher incidence, present atypical and more exuberant clinical features, and is frequently recalcitrant to treatment. Despite this aggravated severity, treatment options for psoriasis...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章,评审
doi:10.1177/0956462419827673
更新日期:2019-05-01 00:00:00
abstract::Stavudine is a potent nucleoside analogue and a well-recognized component of highly active antiretroviral therapy. Clinical trials have shown stavudine to have a superior or at least comparable virological efficacy and immune reconstitution when compared with other nucleoside analogues. Studies have shown that the pre...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章,评审
doi:10.1258/095646203322491842
更新日期:2003-10-01 00:00:00
abstract::People living with HIV (PLH) in Thailand face tremendous challenges, including HIV disclosure. With the advent of antiretroviral (ARV) therapy in Thailand, the positive benefits of HIV disclosure are becoming more salient. However, there are regional variations in the levels of HIV disclosure in Thailand. We examined ...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/ijsa.2009.009008
更新日期:2010-03-01 00:00:00
abstract::A 41-year-old HIV-positive man who has sex with men (MSM) with a family history of deep vein thrombosis (DVT) presented to the emergency department with an acutely swollen lower limb. The initial clinical diagnosis was of a possible DVT and the patient was anticoagulated. However, investigations subsequently excluded ...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/ijsa.2011.011217
更新日期:2012-03-01 00:00:00
abstract::This is the case of a black African woman who presented with three distinct episodes of herpes simplex virus (HSV) infection unresponsive to first-line therapy. Clinical and virological resistance to aciclovir therapy was demonstrated, and although the first two episodes manifested as the deep ulceration often associa...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/095646207780132361
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abstract::Although important, the foreskin is not absolutely essential to penile function. Dysfunction is common and a cause of considerable morbidity, and is sometimes associated with mortality from squamous cell carcinoma (SCC). Penile dermatoses herald, complicate or cause preputial dysfunction. Their effective diagnosis and...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章,评审
doi:10.1258/0956462011922922
更新日期:2001-04-01 00:00:00
abstract::The purpose of this study was to examine, among 2 groups of individuals with different risk profiles, the similarity of their attitudes towards vaccines for sexually transmitted diseases (STDs) and non-STDs. Subjects were recruited from an undergraduate psychology class at an urban university (n=518) or were participa...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/0956462001915624
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abstract::For the purpose of surveillance of the acquired immunodeficiency syndrome (AIDS) in developing countries, the World Health Organization (WHO) has recommended criteria for the clinical case definition of AIDS in adults and children. In a preliminary examination of children in Zambia a number of patients with obvious AI...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/095646249300400204
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journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/0956462981921189
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journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/0956462414560777
更新日期:2015-10-01 00:00:00
abstract::There are many challenges in providing genitourinary medicine services in prison. A review of current service arrangements is overdue. Developing a national standard for sexual health in prison must be a priority. Clinical governance arrangements underpinned by better health informatics and reliable measures of outcom...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章,评审
doi:10.1258/ijsa.2008.008033
更新日期:2008-07-01 00:00:00
abstract::Pancreatic neuroendocrine tumours (PETs), though rare, are usually slow growing tumours with a relatively good prognosis. We describe a case of an aggressive malignant neuroendocrine tumour of the pancreas occurring in an AIDS patient, which has not been reported previously. ...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/0956462011922841
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abstract::This cross-sectional study assessed beliefs about highly active antiretroviral therapy (HAART) and their association with reported adherence to HAART among 109 HIV-positive patients receiving HAART while attending an ambulatory care clinic in Brighton, UK. Patients' beliefs about the necessity for and concerns about H...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
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abstract::This study examines the use of various direct observation therapy-HAART treatment support modalities in Jos, Nigeria. A 12-month observational study enrolling 175 antiretroviral naïve patients into four arms of direct observation therapy-HAART (highly active antiretroviral therapy); daily observed therapy (DOT), twice...
journal_title:International journal of STD & AIDS
pub_type: 临床试验,杂志文章
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abstract::In 1995, an international team reported that improved syndromic management of sexually transmitted disease (STD) in Mwanza, Tanzania, had reduced HIV incidence by 38% in intervention compared to control communities. However, the team has not addressed confound: project interventions might have reduced HIV transmission...
journal_title:International journal of STD & AIDS
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abstract::There is a need for new hypotheses to supplement existing explanations for the observed differences in HIV prevalence between countries and within countries. Due to high levels of viraemia during the initial phase of HIV infection, networks of concurrent regular partnerships in a community could be the determining fac...
journal_title:International journal of STD & AIDS
pub_type: 社论
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abstract::In a study to determine the herpes simplex virus (HSV) type isolated from patients with primary (first-attack) genital herpes and to identify any clinical or epidemiological features that might influence the reported incidence of any particular viral type, there was almost an equal incidence of HSV-1 and HSV-2 isolate...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
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abstract::The aim of this work was to study the human papillomavirus (HPV) type-distribution in condylomata acuminata (CA) of mainland China and to estimate the potential role of HPV prophylactic vaccines for CA in mainland China. Forty-three studies using polymerase chain reaction to detect HPV were included in this meta-analy...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章,meta分析
doi:10.1258/ijsa.2008.008040
更新日期:2008-10-01 00:00:00