Abstract:
:Peripheral neuropathy is one of the most common neurological complications of HIV infection with a 30-60% lifetime prevalence. Newer HIV drugs cause less peripheral neuropathy, but patients are now living long enough to develop concomitant diabetes-related, vascular-related, and chemotherapy-related neuropathy so it continues as a major debilitating issue. Recent national CDC guidelines have stressed the importance of non-opioid therapies, especially in this population that may have had drug abuse problems. We treated a 52-year-old man who had severe disabling classic peripheral neuropathy since 1998 with Scrambler Therapy (Calmare), an FDA-cleared peripheral non-invasive neuromodulation device. His pain rapidly improved, as did his motor and sensory function, with just four 45-min treatments, and he was able to come off opioids for the first time in years. When his pain returned six months later, only two treatments were needed to resolve it. This represents the first published use of this novel, inexpensive, and non-invasive pain modality in HIV peripheral neuropathy, and should engender further trials.
journal_name
Int J STD AIDSjournal_title
International journal of STD & AIDSauthors
Smith TJ,Auwaerter P,Knowlton A,Saylor D,McArthur Jdoi
10.1177/0956462416656688subject
Has Abstractpub_date
2017-02-01 00:00:00pages
202-204issue
2eissn
0956-4624issn
1758-1052pii
0956462416656688journal_volume
28pub_type
杂志文章abstract::This paper describes the effect of HIV prevention intervention among female sex workers in Delhi. Over a 2-year period we found a marked increase in condom use with little increase in HIV seroprevalence. The prevalence of HIV infection did not increase during the study period (1 positive among 701 in 1988 vs 1 positiv...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/095646249400500113
更新日期:1994-01-01 00:00:00
abstract::We assessed the validity of a syndromic case management approach for reproductive tract infections (RTIs) among 371 pregnant women attending antenatal care facilities in Kingston, Jamaica, using an algorithm previously validated in high-risk Jamaican women. For our antenatal attenders, the algorithm had low sensitivit...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/095646204774195209
更新日期:2004-06-01 00:00:00
abstract::The study was aimed at investigating the conditions and circumstances for the recruitment of prostitutes, as well as their reproductive history, working conditions, knowledge of and attitudes to sexually transmitted diseases (STDs), and use of prophylactic antibiotic therapy of these diseases. Two hundred prostitutes ...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/0956462971919697
更新日期:1997-03-01 00:00:00
abstract::Gonorrhoea and chlamydia infections in women are often regarded as asymptomatic. Syndromic management of sexually transmitted disease (STDs), however, is partially based on vaginal symptoms. We sought to better identify STD-associated symptoms in women by development of composite genitourinary symptom constructs. Stan...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/0956462053057549
更新日期:2005-02-01 00:00:00
abstract::Since 2010, the Thailand Ministry of Public Health has recommended that men who have sex with men (MSM) have an HIV test at least two times a year. We calculated the proportion of, and factors associated with, testing adherence among the HIV-uninfected MSM clients attending Silom Community Clinic @TropMed. We defined ...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/0956462418788724
更新日期:2018-12-01 00:00:00
abstract::Scolecobasidium sp. are commensal soil and water thermophilic dematiaceous fungi. They are commonly isolated as contaminants from respiratory secretions due to their abundant presence in water supplies, but they are also rare yet emerging culprits producing severe opportunistic infections in immunocompromised individu...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/0956462416646688
更新日期:2017-01-01 00:00:00
abstract::The brain gumma is a rare manifestation of the tertiary stage of syphilis. A case of neurosyphilitic gumma was confirmed by the Treponema pallidum polymerase chain reaction in a 46-year-old HIV-positive homosexual man. The patient presented with a severe headache and was hospitalized. A computed tomography scan was pe...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/ijsa.2007.007287
更新日期:2008-08-01 00:00:00
abstract::Successful cervical screening programmes depend on the participation of an informed target population. A national cervical screening programme is shortly to be introduced in the Republic of Ireland. We compare the knowledge, attitudes and practice of 395 Irish urban women with 323 high-risk women, genitourinary medici...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/0956462011916974
更新日期:2001-03-01 00:00:00
abstract::Local genital tract inflammation stimulates leukocyte activity and causes HIV shedding, potentially increasing HIV sexual infectiousness. Although there are available clinical markers for genital tract inflammation, such as urinary leukocyte esterase, none have yet been examined in relation to HIV sexual risk behaviou...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/0956462414536147
更新日期:2015-04-01 00:00:00
abstract::The objective was to comprehensively assess the prevalence of condom-use errors and problems among male clients attending a public sexually transmitted disease (STD) clinic. Men (n = 278) attending an STD clinic completed an anonymous questionnaire. Seven errors and six problems were assessed. Summative scores were te...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/ijsa.2007.007103
更新日期:2008-02-01 00:00:00
abstract::The main purpose of this study was to investigate how loneliness was associated with social support and family function among people living with HIV/AIDS (PLWHA) in an HIV-stricken area of China. Two hundred and nineteen PLWHA were surveyed using the UCLA (University of California at Los Angeles)-Loneliness Scale, the...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/ijsa.2008.008348
更新日期:2009-04-01 00:00:00
abstract::Perigenital molluscum contagiosum in adults is recognized as being a sexually transmitted infection. A retrospective casenote review was performed on patients attending a department of genitourinary medicine (GUM) who had been diagnosed as having molluscum. One or more co-existent sexually transmitted diseases (STD) w...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/095646249100200604
更新日期:1991-11-01 00:00:00
abstract::We aimed to identify factors associated with transmission of human immunodeficiency virus (HIV) from injecting drug users (IDUs) to their wives in Manipur, northeast India, where the prevalence of HIV among IDUs is 80% via a case-control study. One hundred and sixty-one HIV-infected IDUs and their wives were recruited...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/0956462001916137
更新日期:2000-07-01 00:00:00
abstract::The 'dynias' are a group of chronic focal pain syndromes with a predilection for orocervical or urogenital regions. Only exceptionally do they involve both sites in the same patient. Here, we report a case of simultaneous occurrence of dysaesthetic peno/scroto dynia and stomatodynia. ...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/095646205774988154
更新日期:2005-12-01 00:00:00
abstract::A longitudinal study of demographic and behavioural characteristics associated with risky sexual behaviours of young men after release from prison. One hundred and six men were interviewed in prison and at one week and six months after release. Overall, 37% reported a previous sexually transmitted disease (STD) diagno...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/095646203767869110
更新日期:2003-08-01 00:00:00
abstract::Domestic violence (DV) occurs frequently within the UK, with one in four women and one in six men experiencing DV during their life. DV is the leading cause of morbidity for women aged 19-44 years and is associated with sexual health problems. However, few data exist on the prevalence of DV in UK genitourinary (GU) me...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/0956462412472799
更新日期:2013-05-01 00:00:00
abstract::Gonorrhoea in the UK is now a highly focal problem that is localized to certain inner city areas where it presents a significant public health concern. However, the majority of men and a proportion of women infested with Neisseria gonorrhoeae do not experience symptoms of sufficient intensity to prompt them to seek me...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/0956462981922539
更新日期:1998-08-01 00:00:00
abstract::Novel HIV testing strategies may improve the uptake of the test. The aim of the present study was to investigate the uptake of HIV testing during Birmingham Pride events in 2009 and 2010. The project was a collaboration between Whittall Street Clinic and Healthy Gay Life. This was a nurse-delivered service that was of...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/ijsa.2012.012023
更新日期:2012-12-01 00:00:00
abstract::Studies in various regions of the world have shown that women infected with HIV-1 are at increased risk for cervical human papillomavirus (HPV) infection as well as for cervical cancer precursor lesions. HIV infection and cervical cancer are both widespread in West Africa, but little is known about the relationship be...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/095646249400500307
更新日期:1994-05-01 00:00:00
abstract::This study employed culture and polymerase chain reaction (PCR) to examine the prevalence of Ureaplasma urealyticum, Mycoplasma hominis, Mycoplasma genitalium, Mycoplasma fermentans, Mycoplasma penetrans and Mycoplasma pirum in 210 HIV/AIDS patients, 455 sexually transmitted infection (STI) clinic attendees and 245 he...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/ijsa.2009.009396
更新日期:2012-08-01 00:00:00
abstract::The blood-taking practices and prevalence of needle-stick injuries were recorded for 46 house officers working at the two largest teaching hospitals in Sheffield and 38 house officers working at three hospitals in London. Wearing gloves when performing venesection or inserting an intravenous cannula was generally perc...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/095646249100200109
更新日期:1991-01-01 00:00:00
abstract::Previous studies have reported an inverse relationship between condom use and emotional intimacy. The aim of this study was to determine the relationship between condom use and emotional intimacy. The study was a gonorrhoea case-comparison study with the samples being drawn from public health clinics (cases) and selec...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/ijsa.2009.009238
更新日期:2009-11-01 00:00:00
abstract::A seasonal variation in the presentation of Pneumocystis jirovecii pneumonia (PCP) has been reported and a previous study from this centre noted a seasonal variation in mortality rates. This study examined seasonal influences (including climatic factors) within-host factors (clinical and laboratory-derived variables),...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/ijsa.2010.010148
更新日期:2010-07-01 00:00:00
abstract::We examined treatment-seeking behaviours amongst a consecutive sample of 188 first-time attenders at a busy genitourinary (GU) clinic in a general hospital. Participants were interviewed and completed a battery of questionnaires prior to receiving diagnosis or treatment. Delay in treatment seeking was measured in 3 wa...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/0956462001916083
更新日期:2000-06-01 00:00:00
abstract::The objective of the study was to compare the impact of oral and i.v. ganciclovir on resource use and direct health care costs, from the perspective of the UK National Health Service (NHS). The analytical framework used was cost analysis. The sources of data were an open, randomized clinical trial, and additional rese...
journal_title:International journal of STD & AIDS
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1258/0956462961918383
更新日期:1996-10-01 00:00:00
abstract::Chlamydia trachomatis and Neisseria gonorrhoeae testing guidance recommends extragenital screening with locally validated nucleic acid amplification tests, with anatomical sites tested separately. Evidence supports multi-patient combined aliquot pooled sampling (PS) for population screening; evidence for within-patien...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/0956462417742318
更新日期:2018-05-01 00:00:00
abstract::Few analytic opportunities have allowed us to evaluate the role that specific sexual acts and male latex condoms play in the acquisition of external anal warts (EAW) using longitudinal data. The acquisition of EAWs occurs from epithelial contact with other HPV-infected surfaces, and hence is dependent upon sexual beha...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章,多中心研究
doi:10.1258/0956462053420176
更新日期:2005-03-01 00:00:00
abstract::Herpes simplex virus type 2 (HSV-2) HIV co-infection is common and associated with increased risk of HIV transmission. HSV-2 seroprevalence was assessed on stored samples from baseline and one year follow-up from 81 patients identified with acute HIV infection and 81 age-matched chronically infected men. HSV-2 seropre...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/ijsa.2011.010551
更新日期:2011-08-01 00:00:00
abstract::In order to evaluate the occurrence of hepatotoxicity in patients treated with antiretroviral therapy (ART) who switch protease inhibitor (PI), and the role of viral hepatitis in its development, we performed a retrospective study on 182 HIV patients treated with ART for 24 months. The presence of hepatitis viruses an...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/0956462053057585
更新日期:2005-02-01 00:00:00
abstract::The effect of low pH, normally present in the female genital tract, on HIV viability was examined. HIV is more acid stable than previously reported with no substantial reduction in infectivity occurring until pH levels are reduced below 4.5. The virucidal activity of 3 topical spermicides and chlorhexidine was assesse...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/095646249500600409
更新日期:1995-07-01 00:00:00