Abstract:
:The objective of the study was to compare the impact of oral and i.v. ganciclovir on resource use and direct health care costs, from the perspective of the UK National Health Service (NHS). The analytical framework used was cost analysis. The sources of data were an open, randomized clinical trial, and additional research which collected resource use and cost data. From the perspective of the UK NHS, the expected cost of i.v. ganciclovir for initial induction and 140 days maintenance and reinduction therapy was pounds 730 higher than that of oral (pounds 8145 vs pounds 7415). Conservative estimates which did not favour oral ganciclovir were used wherever possible. Overall, the resource use and costs of maintenance therapy with oral ganciclovir calculated in the model used for this study were lower than those of i.v. ganciclovir, principally reflecting lower costs for the administration of therapy. In this model the drug cost of ganciclovir maintenance therapy was excluded.
journal_name
Int J STD AIDSjournal_title
International journal of STD & AIDSauthors
Davies L,Maynard Adoi
10.1258/0956462961918383subject
Has Abstractpub_date
1996-10-01 00:00:00pages
415-21issue
6eissn
0956-4624issn
1758-1052journal_volume
7pub_type
临床试验,杂志文章,多中心研究,随机对照试验abstract::Given the disproportionate HIV burden faced by female sex workers FSWs and limited data regarding their engagement in the HIV cascade of care in conflict-affected settings, we characterized the cascade of care and examined associations with new HIV diagnoses and antiretroviral therapy (ART) use in a community-based co...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/0956462418804658
更新日期:2019-03-01 00:00:00
abstract::Using data from the Prevention of Pelvic Infection (POPI) chlamydia screening trial, we compared the characteristics of female students who did or did not get tested for chlamydia outside the trial during 12 months' follow-up. Of the 2529 women in the trial, we excluded 68 chlamydia positives in the intervention group...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/0956462415587636
更新日期:2016-06-01 00:00:00
abstract::A study on STDs was conducted among 211 female inmates in a prison in Lisbon, Portugal, in order to establish possible associations between Trichomonas vaginalis infection, sociodemographic factors and other STDs. T. vaginalis was found in 31.2% of the women, from whom only 65.1% presented symptoms. It was more freque...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/0956462041724235
更新日期:2004-09-01 00:00:00
abstract::In an audit of HIV post-exposure prophylaxis (PEP) programmes in Blantyre, Malawi, and Liverpool, UK, a striking common deficiency was poor attendance of follow-up visits and of HIV testing to determine efficacy of PEP. Causes of poor follow-up after PEP need to be explored in both settings. ...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/ijsa.2011.010423
更新日期:2011-12-01 00:00:00
abstract::Antiretroviral treatment roll-out programmes in Africa often have difficulties to cope with the increasing number of clients. Based on the findings of a survey carried out in 2005 that showed long waiting times, innovative organizational changes (nurse visits and pharmacy-only refill visits) were introduced in our cli...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/ijsa.2008.008174
更新日期:2009-02-01 00:00:00
abstract::Background In Kenya, HIV incidence and prevalence have declined. HIV rates are lower in rural areas than in urban areas. However, HIV infection is reported higher in men in rural areas (4.5%) compared to those in urban areas (3.7%). Objectives This study examined HIV knowledge, feelings, and interactions towards HIV-i...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/0956462416680764
更新日期:2017-08-01 00:00:00
abstract::This study assessed lubricant use during receptive anal intercourse (RAI) among Peruvian men who have sex with men (MSM) and willingness to use a hypothetical rectal microbicide (RM) formulated as a lubricant to prevent HIV infection. Data were collected from 843 Peruvian MSM for the 2008 HIV Sentinel Surveillance usi...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/ijsa.2010.010134
更新日期:2010-08-01 00:00:00
abstract::Genital ulcer disease as a risk factor for HIV transmission has become apparent in the fight against AIDS. In poor communities in developing countries with people living under low hygienic conditions chancroid is often reported to be the most common form of genital ulcer. It is caused by Haemophilus ducreyi; a fastidi...
journal_title:International journal of STD & AIDS
pub_type: 社论,评审
doi:10.1177/095646249300400602
更新日期:1993-11-01 00:00:00
abstract::UK post-exposure prophylaxis (PEP) guidelines were updated by the British Association for Sexual Health and HIV (BASHH) in 2011. In 2013, we changed policy to omit day 5 PEP follow-up at 56 Dean Street as it was felt clinically unnecessary. This audit compares our performance against BASHH standards for PEP attenders ...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/0956462414547090
更新日期:2015-07-01 00:00:00
abstract::This is a cross-sectional study based on an open web survey with the primary objective to assess associations between the use of apps for seeking sex partners and vulnerabilities related to human immunodeficiency virus (HIV) acquisition among men who have sex with men (MSM) in Brazil. Participants were recruited to th...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/0956462420945940
更新日期:2020-10-01 00:00:00
abstract::Summary HIV transmission risk is increased during antiretroviral therapy (ART) use if individuals are not virologically suppressed and engage in high risk transmission behaviour. Baseline data of HIV-infected men who have sex with men (MSM) with recent history of risky behaviour on ART for ≥3 months (n = 139) were eva...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/0956462413518500
更新日期:2014-09-01 00:00:00
abstract::This study examines the use of various direct observation therapy-HAART treatment support modalities in Jos, Nigeria. A 12-month observational study enrolling 175 antiretroviral naïve patients into four arms of direct observation therapy-HAART (highly active antiretroviral therapy); daily observed therapy (DOT), twice...
journal_title:International journal of STD & AIDS
pub_type: 临床试验,杂志文章
doi:10.1258/095646207782212252
更新日期:2007-11-01 00:00:00
abstract::The aim of this study was to investigate the factors relating to CD4 level at HIV diagnosis and HIV testing behaviour. Participants were newly diagnosed patients (n = 654) in Japan from 2000 to 2005. Around 75% of participants were diagnosed at hospital and clinics. Mean CD4 counts at diagnosis through voluntary HIV t...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/ijsa.2009.009493
更新日期:2012-04-01 00:00:00
abstract::The epidemic of HIV/AIDS greatly threatens Chinese youth. Our study was intended to examine the effectiveness of the peer education method in HIV/AIDS prevention in different types of senior high schools in Shanghai. A peer education intervention was conducted in 10 different types of senior high schools, including th...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/ijsa.2008.008053
更新日期:2008-11-01 00:00:00
abstract::The objective of this study was to audit the management of syphilis in our integrated sexual health clinic according to the British Association for Sexual Health and HIV (BASHH) guideline using the 'Treponemal Infection Care' (TIC) audit tool devised by our clinic. The case notes of patients diagnosed with all stages ...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/ijsa.2011.010392
更新日期:2011-05-01 00:00:00
abstract::Increasing numbers of HIV-infected children are now reaching adulthood and young people account for 10% of new HIV diagnosis in the UK each year. This audit of young people attending specialist and generic HIV services in Inner London in 2006 (n=39) highlights the complex medical and psychosocial needs of this patient...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/095646207781568565
更新日期:2007-09-01 00:00:00
abstract::This paper assesses the associations between intimate partner violence (IPV) and sexually transmitted infections (STIs) and sexual risks among HIV-positive female drinkers in St Petersburg, Russia. Survey and STI data were analysed from 285 women in HERMITAGE, a secondary prevention study of HIV-positive heavy drinker...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/0956462412472809
更新日期:2013-04-01 00:00:00
abstract::Our objective was to determine the prevalence of HIV and the distribution of HIV-related diseases among adult, medical inpatients. Consecutive admissions were recruited and a single ELISA assay was used to determine HIV infection. Demographic and clinical details were extracted from clinical records. Of 507 patients, ...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/0956462011923336
更新日期:2001-06-01 00:00:00
abstract::Genital elephantiasis (esthiomene), which is the dramatic end-result of lymphatic obstruction, is rather rare. Although mainly associated with filariasis and sexually transmitted diseases, such as lymphogranuloma venereum and donovanosis, it could also be an uncommon complication of tubercular lymphadenitis, a common ...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/095646202760029886
更新日期:2002-06-01 00:00:00
abstract::Sweden was the first country to introduce online Chlamydia trachomatis testing for both men and women and this article provides information about the user characteristics and which risk groups are reached with this method. During the years 2005-2007 a questionnaire was administered with a response rate of 86% (n = 602...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/ijsa.2011.011030
更新日期:2012-02-01 00:00:00
abstract::Highly active antiretroviral therapy (HAART) has transformed HIV-1 infection from an invariably fatal disease into a chronic infection requiring lifelong treatment. However, the challenges we still face are the urgent need to provide affordable sustainable therapy to the millions of infected individuals who live in re...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章,评审
doi:10.1258/095646206777689035
更新日期:2006-07-01 00:00:00
abstract::Scolecobasidium sp. are commensal soil and water thermophilic dematiaceous fungi. They are commonly isolated as contaminants from respiratory secretions due to their abundant presence in water supplies, but they are also rare yet emerging culprits producing severe opportunistic infections in immunocompromised individu...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/0956462416646688
更新日期:2017-01-01 00:00:00
abstract::We retrospectively analysed routinely collected baseline data of 2252 patients with HIV infection registered in the National Free Antiretroviral Treatment Program in Xinjiang province, China, from 2006 to 2011 to estimate the prevalence and predictors of anaemia at the initiation of combined antiretroviral therapy. An...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/0956462414531935
更新日期:2015-03-01 00:00:00
abstract::We aim to clarify the prevalence of Mycoplasma genitalium in asymptomatic men in Japan. First-catch urine specimens were obtained from 187 asymptomatic Japanese men and examined for the presence of M. genitalium using a polymerase chain reaction (PCR)-based assay. Two (1.1%) of 187 first-catch urine specimens were pos...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/0956462971919877
更新日期:1997-04-01 00:00:00
abstract::It is important to assess uptake of a new vaccine. The present survey estimated the uptake of the recently introduced human papillomavirus vaccine (HPVV) in the emirate of Abu Dhabi and also explored barriers to uptake. A questionnaire survey was conducted in secondary schools, enrolling 334 girls. The uptake percenta...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/ijsa.2009.009380
更新日期:2011-07-01 00:00:00
abstract::Little is known about the incidence of bacterial sexually transmitted infections (STIs) among HIV-infected versus HIV-uninfected adolescents. This secondary analysis of a national, multisite study included adolescents aged 12-18 years who were behaviourally HIV-infected (n = 346) or HIV-uninfected but at-risk (n = 182...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/0956462412472425
更新日期:2013-02-01 00:00:00
abstract::Since 2010, the Thailand Ministry of Public Health has recommended that men who have sex with men (MSM) have an HIV test at least two times a year. We calculated the proportion of, and factors associated with, testing adherence among the HIV-uninfected MSM clients attending Silom Community Clinic @TropMed. We defined ...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/0956462418788724
更新日期:2018-12-01 00:00:00
abstract::Due to demographic changes in people living with HIV (PLHIV), physicians are challenged with age-related comorbidities and their management. In the absence of comprehensive data collection, the burden of comorbidities and co-medication in addition to antiretroviral therapy (ART) remains unclear for the German real-wor...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/0956462420942020
更新日期:2020-12-15 00:00:00
abstract::We assessed the validity of self-reported sex and condom use by comparing self-reports with prostate-specific antigen (PSA) detection in a prospective study of 210 female sex workers in Mombasa, Kenya. Participants were interviewed on recent sexual behaviours at baseline and 12-month follow-up visits. At both visits, ...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/095646207779949899
更新日期:2007-01-01 00:00:00
abstract::We present a case of acute limbic encephalitis secondary to HIV seroconversion. The patient made a gradual neurological recovery following treatment with antiretroviral therapy, steroids and intravenous immunoglobulin. ...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/ijsa.2011.010331
更新日期:2011-04-01 00:00:00