Abstract:
:This study examines the use of various direct observation therapy-HAART treatment support modalities in Jos, Nigeria. A 12-month observational study enrolling 175 antiretroviral naïve patients into four arms of direct observation therapy-HAART (highly active antiretroviral therapy); daily observed therapy (DOT), twice weekly observed therapy (TWOT), weekly observed therapy (WOT) and self-administered therapy (SAT), examined community treatment support using family and community members. Treatment outcomes were much better in the treatment-supported groups compared with the control self-therapy group. CD4 cell increases were 218/microL (DOT), 267/microL (TWOT), 205/microL (WOT) versus 224/microL (SAT), whereas plasma HIV-1 RNA reached undetectable levels (<400 copies/mL) in 91%, 88%, 84% versus 79% of patients in the DOT, TWOT, WOT versus SAT groups, respectively, at 48 weeks. We, therefore, strongly support the use of treatment support in our settings.
journal_name
Int J STD AIDSjournal_title
International journal of STD & AIDSauthors
Idoko JA,Agbaji O,Agaba P,Akolo C,Inuwa B,Hassan Z,Akintunde L,Badung B,Muazu M,Danang M,Imade G,Sankale JL,Kanki Pdoi
10.1258/095646207782212252subject
Has Abstractpub_date
2007-11-01 00:00:00pages
760-3issue
11eissn
0956-4624issn
1758-1052journal_volume
18pub_type
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