Abstract:
:The Senegal pre-exposure prophylaxis (PrEP) Demonstration Project was an open-label cohort study assessing the delivery of daily oral PrEP to HIV-negative female sex workers (FSWs) in four Ministry of Health (MoH)-run clinics in Dakar, Senegal. We assessed uptake, retention in care, and adherence over up to 12 months of follow-up as well as HIV infection rates. Between July and November 2015, 350 individuals were approached and 324 (92.6%) were preliminarily eligible. Uptake was high, with 82.4% of eligible participants choosing to enroll and take PrEP. The mean age of those enrolled was 37.7 years (SD = 8.7), and approximately half had not attended school (41.2%). Among the 267 participants who were prescribed PrEP, 79.9 and 73.4% were retained in PrEP care at 6 and 12 months, respectively. Older age among FSWs was found to be the only significant predictor of lower discontinuation. We did not find significant differences in retention by site, education, condom use, or HIV risk perception. There were no new HIV infections at follow-up. Our results showed evidence of high interest in PrEP and very good PrEP retention rates among FSWs at 12-month follow-up when offered in MoH-run clinics, with older age as the only significant predictor of higher PrEP retention. This highlights the role that these clinics can play in expanding PrEP access nationwide.
journal_name
Int J STD AIDSjournal_title
International journal of STD & AIDSauthors
Sarr M,Gueye D,Mboup A,Diouf O,Bao MDB,Ndiaye AJ,Ndiaye BP,Hawes SE,Tousset E,Diallo A,Jones F,Kane CT,Thiam S,Ndour CT,Gottlieb GS,Mboup Sdoi
10.1177/0956462420943704subject
Has Abstractpub_date
2020-10-01 00:00:00pages
1063-1072issue
11eissn
0956-4624issn
1758-1052journal_volume
31pub_type
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