Abstract:
:The purpose of this study was to investigate whether Epstein-Barr virus (EBV) is associated with acetowhite lesions of the portio cervix, demonstrating koilocytosis and/or cervical intraepithelial neoplasia (CIN) I-III. The study group comprised 37 women admitted to the Department of Gynaecology and Obstetrics, Sahlgrenska University Hospital, Göteborg because of pathological colposcopy or cytology of the portio cervix. Colposcopically, all exhibited acetowhite lesions of the portio cervix. Cells were sampled with a cytobrush for examination for EBV and human papillomavirus (HPV) DNA by polymerase chain reaction (PCR) and a biopsy was taken for histopathology. Biopsies from 5 patients positive for EBV by PCR in cervical cell samples were examined by an in situ hybridization technique for EBER (Epstein-Barr virus encoded RNA), RNAs expressed in latent EBV infection. The control group consisted of women attending the Department of Dermato-Venereology at the same hospital for STD check-up. These had a normal cytology and no signs of acetowhiteness of the portio cervix. In the study group, EBV DNA was found in 30% and HPV DNA in 51%. In the control group 57% exhibited EBV DNA and 23% HPV DNA. EBV was not found to be a predictive factor in the development of koilocytosis and/or CIN I-III. HPV was a predictive factor in acetowhite, koilocytotic lesions. No expression of EBER was found in the 5 biopsies examined by in situ hybridization.
journal_name
Int J STD AIDSjournal_title
International journal of STD & AIDSauthors
Voog E,Ricksten A,Stenglein M,Jonassen F,Ternesten A,Ryd W,Löwhagen GBdoi
10.1258/0956462971920488subject
Has Abstractpub_date
1997-07-01 00:00:00pages
432-6issue
7eissn
0956-4624issn
1758-1052journal_volume
8pub_type
杂志文章abstract::We examined the association between education and prevalent HIV-1 infection in the Rakai district, rural Uganda based on a cross-sectional analysis of a population-based cohort. In 1990, 1397 men and 1705 women aged 13 years and older, were enrolled in 31 randomly selected communities. Strata were comprised of main ro...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/0956462991914456
更新日期:1999-07-01 00:00:00
abstract::Herpes simplex virus 1 and 2 (HSV-1 and HSV-2) infections continue to be among the most common and unrecognized sexually transmitted infections in the world. Although treatable, HSV-1 and HSV-2 infections remain incurable. Hence, there is interest in the development of a vaccine to prevent genital herpes. As part of a...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章,随机对照试验
doi:10.1177/0956462412472822
更新日期:2013-05-01 00:00:00
abstract::A group of 14 women infected with hepatitis C virus (HCV) was evaluated for vaginal shedding of the virus. The HCV-RNA detection was performed in plasma, peripheral blood mononuclear cells (PBMC) and in supernatant and pellet of vaginal washings. HCV-RNA positive results were obtained in all plasma samples, in 57% of ...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/0956462011924209
更新日期:2001-11-01 00:00:00
abstract::A 21-year-old man presented to genitourinary (GU) medicine physicians with (initially) painful penile and scrotal swelling. A diagnosis of ano-genital granulomatosis was confirmed on histological analysis of penile skin. Enquiring about systemic symptoms resulted in the additional diagnosis of gastrointestinal Crohn's...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/ijsa.2012.012183
更新日期:2013-02-01 00:00:00
abstract::Local genital tract inflammation stimulates leukocyte activity and causes HIV shedding, potentially increasing HIV sexual infectiousness. Although there are available clinical markers for genital tract inflammation, such as urinary leukocyte esterase, none have yet been examined in relation to HIV sexual risk behaviou...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/0956462414536147
更新日期:2015-04-01 00:00:00
abstract::Integrase strand transfer inhibitors (INSTIs) are a class of antiretroviral drugs with high virologic efficacy and excellent tolerability. Recent evidence showed a possible link of dolutegravir-based regimens with weight gain, and a relationship between raltegravir use and changes in adipose tissue density and metabol...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/0956462420955075
更新日期:2020-12-01 00:00:00
abstract::The incidence of anogenital warts (condyloma acuminatum) is rapidly increasing while there is still no totally satisfactory treatment available. In light of the emphasis of experimental approaches toward the prevention of viral replication and evidence of the antiviral action of lithium salts it was proposed to invest...
journal_title:International journal of STD & AIDS
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1258/0956462971920677
更新日期:1997-08-01 00:00:00
abstract::The aim of the study was to provide more comprehensive data on the clinical characteristics of hospitalized AIDS patients in Cambodia. Chart review of 381 HIV-infected patients admitted to a public hospital in Phnom Penh, Cambodia between December 1999 and May 2000 was performed. The in-hospital mortality rate was 43....
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/095646203765371312
更新日期:2003-06-01 00:00:00
abstract::Individuals with substance use disorders (SUDs) are at higher risk of HIV infection, yet recent studies show rates of HIV testing are low among this population. We implemented and evaluated a nurse-initiated HIV oral rapid testing (NRT) strategy at three Veterans Health Administration SUD clinics. Implementation of NR...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/ijsa.2012.012050
更新日期:2012-11-01 00:00:00
abstract::A 23-year-old man was admitted to our hospital with severe thrombocytopaenia. He had unprotected sexual contact 6 weeks earlier. He was diagnosed with acute HIV infection by means of HIV RNA viral load testing and HIV-associated thrombocytopaenia. Although his thrombocytopaenia improved immediately with short-term dex...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/0956462414531937
更新日期:2015-03-01 00:00:00
abstract::Perigenital molluscum contagiosum in adults is recognized as being a sexually transmitted infection. A retrospective casenote review was performed on patients attending a department of genitourinary medicine (GUM) who had been diagnosed as having molluscum. One or more co-existent sexually transmitted diseases (STD) w...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/095646249100200604
更新日期:1991-11-01 00:00:00
abstract::The primary aim of the current study was to test the effect of the presentation design of a test alert system on healthcare workers' (HCWs') decision-making regarding blood-borne virus (BBV) testing. The secondary aim was to determine HCWs' acceptance of the system. An online survey used a within-subjects research des...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/0956462420906998
更新日期:2020-07-01 00:00:00
abstract::Our objectives were to determine the prevalence of Neisseria gonorrhoeae and its association with other STD causing organisms. Three hundred and thirty-six consecutive women (female sex workers (FSWs) and married contacts), attending a sexually transmitted disease (STD) clinic in Mumbai, were screened for N. gonorrhoe...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/0956462001914896
更新日期:2000-01-01 00:00:00
abstract::Seventy-two blood donors who were tested positive by the Singapore Blood Transfusion Service (SBTS) for Treponema pallidum haemagglutination (TPHA) test, were evaluated at the Department of Sexually Transmitted Diseases Clinic (DSC) between November 1994 to December 1996. All underwent syphilis serological testing, in...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/0956462971919237
更新日期:1997-12-01 00:00:00
abstract::Since 2010, the Thailand Ministry of Public Health has recommended that men who have sex with men (MSM) have an HIV test at least two times a year. We calculated the proportion of, and factors associated with, testing adherence among the HIV-uninfected MSM clients attending Silom Community Clinic @TropMed. We defined ...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/0956462418788724
更新日期:2018-12-01 00:00:00
abstract::This study employed culture and polymerase chain reaction (PCR) to examine the prevalence of Ureaplasma urealyticum, Mycoplasma hominis, Mycoplasma genitalium, Mycoplasma fermentans, Mycoplasma penetrans and Mycoplasma pirum in 210 HIV/AIDS patients, 455 sexually transmitted infection (STI) clinic attendees and 245 he...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/ijsa.2009.009396
更新日期:2012-08-01 00:00:00
abstract::Adolescents are at high risk for HIV acquisition, and thus need to be included in HIV vaccine trials. In preparation for inclusion of adolescents in HIV vaccine trials in an urban community in Cape Town with a high antenatal HIV prevalence, the study assessed the attitudes towards the inclusion of adolescents in HIV v...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/ijsa.2009.008484
更新日期:2010-03-01 00:00:00
abstract::UK post-exposure prophylaxis (PEP) guidelines were updated by the British Association for Sexual Health and HIV (BASHH) in 2011. In 2013, we changed policy to omit day 5 PEP follow-up at 56 Dean Street as it was felt clinically unnecessary. This audit compares our performance against BASHH standards for PEP attenders ...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/0956462414547090
更新日期:2015-07-01 00:00:00
abstract::The objective of the study was to compare the impact of oral and i.v. ganciclovir on resource use and direct health care costs, from the perspective of the UK National Health Service (NHS). The analytical framework used was cost analysis. The sources of data were an open, randomized clinical trial, and additional rese...
journal_title:International journal of STD & AIDS
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1258/0956462961918383
更新日期:1996-10-01 00:00:00
abstract::Our objective was to analyse the characteristics of patients who were unaware of their HIV infection until they developed AIDS, in the period after introduction of highly active antiretroviral therapy. The complete national register of HIV and AIDS cases reported to the Department of Epidemiology at the Swedish Instit...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/095646205774357262
更新日期:2005-10-01 00:00:00
abstract::We describe a case of cryptococcal meningitis in a patient known to have HIV who presented initially with ocular cryptococcosis. This case highlights to clinicians the need to be aware of this association and to carry out relevant investigations so as to treat these patients appropriately. ...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/ijsa.2009.009132
更新日期:2012-05-01 00:00:00
abstract::Requests for hepatitis C antibodies (HCV Ab) made by the Oxford Department of Genito-urinary (GU) Medicine were audited against national guidelines to determine how the service performed and to develop locally applicable standards. This resulted in more effective screening and cost savings. ...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/095646206777689026
更新日期:2006-07-01 00:00:00
abstract::We evaluated Cobas Amplicor, a highly automated polymerase chain reaction (PCR) system, to test first-void urine (FVU) and urethral swab specimens for Chlamydia trachomatis and Neisseria gonorrhoeae in men attending a sexually transmitted infection (STI) clinic. Results were compared against an in-house radioimmune do...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/0956462981921594
更新日期:1998-01-01 00:00:00
abstract::Pancreatic neuroendocrine tumours (PETs), though rare, are usually slow growing tumours with a relatively good prognosis. We describe a case of an aggressive malignant neuroendocrine tumour of the pancreas occurring in an AIDS patient, which has not been reported previously. ...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/0956462011922841
更新日期:2001-04-01 00:00:00
abstract::Recognising the initial clinical presentation of acute HIV infection could enable earlier initiation of antiretroviral therapy and appropriate counselling to reduce the risk of transmission to others. Herein, we describe an unusual case of acute HIV infection presenting as limbic encephalitis and rhabdomyolysis. ...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/0956462414560777
更新日期:2015-10-01 00:00:00
abstract::HIV disproportionately affects men who have sex with men (MSM). Substance use is common among people living with HIV and may affect antiretroviral therapy adherence. Nevertheless, research examining the association between substance use and viral suppression is lacking. The aims of this study were to determine the ass...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/0956462418779663
更新日期:2018-10-01 00:00:00
abstract::The incidence of disseminated Mycobacterium avium complex (MAC) infection in HIV patients has fallen markedly since the introduction of effective antiretroviral therapy (ART). However, current guidelines still recommend primary prophylaxis. We conducted a retrospective cohort study in a university-affiliated hospital ...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/0956462417713432
更新日期:2017-12-01 00:00:00
abstract::The objective of this study was to assess the impact on men's liking for the condoms they use of a range of factors including demographic variables and variables that describe men's experience of using particular condoms. One hundred and ninety-four men used 3765 condoms for which they provided a liking rating. The co...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/0956462991913907
更新日期:1999-04-01 00:00:00
abstract::The objective was to comprehensively assess the prevalence of condom-use errors and problems among male clients attending a public sexually transmitted disease (STD) clinic. Men (n = 278) attending an STD clinic completed an anonymous questionnaire. Seven errors and six problems were assessed. Summative scores were te...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/ijsa.2007.007103
更新日期:2008-02-01 00:00:00
abstract::We investigated our patients' preferences for weekend services at the same time as commencing a new Saturday clinic. Patients were asked for their views on weekend services: 374 questionnaires were returned; 210 (56%) from women and 164 (44%) from men. Saturday services were rated as more important than Sunday service...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/ijsa.2009.009208
更新日期:2010-04-01 00:00:00