Abstract:
:Adolescents are at high risk for HIV acquisition, and thus need to be included in HIV vaccine trials. In preparation for inclusion of adolescents in HIV vaccine trials in an urban community in Cape Town with a high antenatal HIV prevalence, the study assessed the attitudes towards the inclusion of adolescents in HIV vaccine trials. A total of 18 focus group discussions were conducted using a semistructured interview guide. The participants (n = 200) were adolescents, young adults, parents and other key informants. Participants from all groups welcomed the inclusion of adolescents in HIV vaccine trials due to their high-risk status. There were, however, concerns about sexual disinhibition, fear of side-effects, fear of HIV testing and disclosure of HIV status, mistrust of nurses and clinics. The study highlighted a number of ethical and social issues that need to be addressed before the trials.
journal_name
Int J STD AIDSjournal_title
International journal of STD & AIDSauthors
Jaspan HB,Soka NF,Mathews C,Flisher AJ,Mark D,Middelkoop K,Wood R,Bekker LGdoi
10.1258/ijsa.2009.008484subject
Has Abstractpub_date
2010-03-01 00:00:00pages
172-6issue
3eissn
0956-4624issn
1758-1052pii
21/3/172journal_volume
21pub_type
杂志文章abstract::The Department of Health has addressed access to genitourinary medicine services by setting targets that 100% of patients should be offered an appointment within 48 hours of contact and 95% should be seen within 48 hours. Such rapid access appointments are often declined by patients. We wished to ascertain whether pat...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/ijsa.2008.008513
更新日期:2009-09-01 00:00:00
abstract::The transition of clinical trial data to changes in routine clinical practice is often a slow process. We describe a rapid transition of patients from one form of antiviral therapy to a modified and potentially safer version that can occur quickly when there are no financial or organisational restrictions on the presc...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/0956462418761260
更新日期:2018-09-01 00:00:00
abstract::The objective of this study was to audit the management of syphilis in our integrated sexual health clinic according to the British Association for Sexual Health and HIV (BASHH) guideline using the 'Treponemal Infection Care' (TIC) audit tool devised by our clinic. The case notes of patients diagnosed with all stages ...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/ijsa.2011.010392
更新日期:2011-05-01 00:00:00
abstract::Neisseria gonorrhoeae isolates that were resistant to ciprofloxacin and/or penicillin were analysed to investigate the escalating problem of antibiotic-resistant gonorrhoea in the north east of England. Opa-typing (outer membrane opacity protein) was carried out on isolates resistant to ciprofloxacin and of nutrient n...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/095646202321020044
更新日期:2002-12-01 00:00:00
abstract::In an audit of HIV post-exposure prophylaxis (PEP) programmes in Blantyre, Malawi, and Liverpool, UK, a striking common deficiency was poor attendance of follow-up visits and of HIV testing to determine efficacy of PEP. Causes of poor follow-up after PEP need to be explored in both settings. ...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/ijsa.2011.010423
更新日期:2011-12-01 00:00:00
abstract::Syphilis rates have been increasing in men who have sex with men (MSM) in London. To describe risk behaviour and refine public health interventions, we conducted prospective enhanced surveillance of new syphilis cases in MSM attending selected London sexual health clinics (SHCs) between October 2016 and January 2017. ...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/0956462418814998
更新日期:2019-04-01 00:00:00
abstract::An innovative six-month, two sessions a week, funded clinical attachment programme was devised and introduced for practical training and experience to meet the demands and requirements of those wishing practical experience and training in genitourinary medicine. This has been generated by interest from previous theore...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/0956462041211234
更新日期:2004-07-01 00:00:00
abstract::'Fuckbuddies' are a type of regular sexual partner with whom men have ongoing sexual contact, generally in the absence of romantic attachment. We surveyed 989 men who have sex with men (MSM) at the Melbourne Sexual Health Centre, Australia, with the aim of determining the frequency of 'fuckbuddy' partnerships among se...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/0956462417717647
更新日期:2018-01-01 00:00:00
abstract::National guidelines state that hepatitis B and C testing should be targeted to those with risk factors. However, there is little data to support this recommendation. There is also limited data of viral hepatitis prevalence in attendees at genitourinary medicine clinics. We report the prevalence of hepatitis B infectio...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/0956462416641528
更新日期:2017-03-01 00:00:00
abstract::The clinical utility of genotypic drug resistance testing (DRT) in HIV-infected children on antiretroviral therapy (ART) is not well understood. HIV-infected patients aged <19 years undergoing DRT for virological failure were retrospectively enrolled. Indications for DRT and changes in HIV RNA load were recorded. Betw...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/0956462412473958
更新日期:2013-07-01 00:00:00
abstract::Since 1995 infectious syphilis has re-emerged in Albania. As syphilis has become more common, more unusual presentations are being recognized. We present a case of an HIV-negative man with primary syphilis presenting with multiple penile ulcers and negative rapid plasma reagin and Venereal Disease Research Laboratory ...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/ijsa.2009.008463
更新日期:2010-03-01 00:00:00
abstract::The transmission efficiency of HIV-1 through unsafe medical injections can be estimated from seroconversions among health care workers (HCWs) after percutaneous exposures and documented iatrogenic outbreaks. Data from a case-control study of seroconversion after percutaneous exposures among US and European HCWs shows ...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/0956462021924820
更新日期:2002-03-01 00:00:00
abstract::Over a 13-year period non-gonococcal neisseriae (NGN) were isolated from 114 of 88,670 patients (0.13%) screened for anogenital gonorrhoea at a Genitourinary Medicine Unit. During the same period there were approximately 9000 anogenital gonococcal infections (10%). The prevalence of NGN was 0.09% (27/31,500) in women,...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/095646249300400103
更新日期:1993-01-01 00:00:00
abstract::These clinical standards for the screening and management of acquired syphilis in HIV-positive patients in the UK were first made available on the MSSVD website in February 2002. They have been updated by the 2006 UK National Guideline on the Sexual Health of People with HIV which is also published in this issue of th...
journal_title:International journal of STD & AIDS
pub_type: 指南,杂志文章
doi:10.1258/095646206778113096
更新日期:2006-09-01 00:00:00
abstract::Primary HIV can be asymptomatic or result in a severe symptomatic illness. Common symptoms are pyrexia, pharyngitis, malaise, lethargy, maculopapular rash, mucous membrane ulceration, lymphadenopathy and headache. It can be reliably diagnosed by a positive virologic test in the absence of HIV-specific antibodies. Prog...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章,评审
doi:10.1258/0956462021924613
更新日期:2002-02-01 00:00:00
abstract::Domestic violence (DV) occurs frequently within the UK, with one in four women and one in six men experiencing DV during their life. DV is the leading cause of morbidity for women aged 19-44 years and is associated with sexual health problems. However, few data exist on the prevalence of DV in UK genitourinary (GU) me...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/0956462412472799
更新日期:2013-05-01 00:00:00
abstract::We report a case series of HIV/HCV co-infected patients who underwent preemptive antiretroviral therapy modifications to manage clinically significant drug interactions with HCV therapy. Among the 15 patients reviewed, all changed to a raltegravir-based regimen and none experienced a loss of virologic suppression or i...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/0956462415580225
更新日期:2016-03-01 00:00:00
abstract::It is important to assess uptake of a new vaccine. The present survey estimated the uptake of the recently introduced human papillomavirus vaccine (HPVV) in the emirate of Abu Dhabi and also explored barriers to uptake. A questionnaire survey was conducted in secondary schools, enrolling 334 girls. The uptake percenta...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/ijsa.2009.009380
更新日期:2011-07-01 00:00:00
abstract::The first HIV-positive diagnosis among injecting drug users (IDU) in Glasgow was made in 1985. By the end of 1987 prevalence among IDU receiving voluntary attributable tests was 4.8%. Since 1990, an annual cross-sectional survey of HIV prevalence and risk behaviours among 500 current Glasgow IDU has provided a more re...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/095646249400500205
更新日期:1994-03-01 00:00:00
abstract::Individuals infected with HIV who are out of care are at a higher risk of HIV-related morbidity and mortality. It has been difficult to recruit a representative sample of out-of-care patients for epidemiological studies. Using a novel weighting method, we constructed a representative sample of out-of-care HIV patients...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/0956462415608334
更新日期:2016-10-01 00:00:00
abstract::Sexually transmitted rectal infections with Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (GC) have been well documented in men who have sex with men (MSM). Few studies have described infections in women who engage in anal intercourse. We performed testing for rectal infections in women who reported ano-recepti...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/ijsa.2010.009279
更新日期:2010-12-01 00:00:00
abstract::Routinely collected data from clinical sites offering voluntary counselling and testing (VCT) for HIV diagnosis have been used to evaluate the impact of public health interventions; however, there has been considerable diversity in strategies. To gain an understanding of the outcome of these evaluations and provide th...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章,评审
doi:10.1258/ijsa.2009.009005
更新日期:2009-06-01 00:00:00
abstract::Individuals with substance use disorders (SUDs) are at higher risk of HIV infection, yet recent studies show rates of HIV testing are low among this population. We implemented and evaluated a nurse-initiated HIV oral rapid testing (NRT) strategy at three Veterans Health Administration SUD clinics. Implementation of NR...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/ijsa.2012.012050
更新日期:2012-11-01 00:00:00
abstract::In a study to determine the significance of Bacteroides ureolyticus in the lower urogenital tract using a new selective and differential medium, this organism was isolated from 30.1% of asymptomatic men, 37.8% of men with genital warts, and 26.3% of men with non-gonococcal urethritis. Using the same selective medium B...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/095646249200300206
更新日期:1992-03-01 00:00:00
abstract::In 2010/2011, regional commissioners withdrew payment for the fixed-dose combination Combivir, forcing a switch to component drugs. This was deemed clinically acceptable and annual savings of £44 k expected. We estimated the true costs of switching and examined patient outcomes. Information for 46 patients using Combi...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/0956462414530588
更新日期:2015-02-01 00:00:00
abstract::The management of cases of Chlamydia trachomatis genital infection diagnosed in clinics in Wessex in the last quarter of 1996 was surveyed, and the results compared with those obtained in the national gonorrhoea audit. Treatment regimens were extremely varied both between and within clinics. Overall, 71% of patients s...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/0956462981921675
更新日期:1998-02-01 00:00:00
abstract::From June to December 1990, 806 prostitutes registered with the STD programme in Singapore for regular screening for sexually transmitted diseases (STD) were investigated for factors associated with STD incidence in the preceding year. The majority were foreigners (92.7% Malaysians and 3.1% Thais). Anal sex (0.4%) and...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/095646249200300506
更新日期:1992-09-01 00:00:00
abstract::The objective of this study was to describe the prevalence of sexually transmitted infections (STI), sociodemographic and behavioural characteristics in a population of male sex workers (MSW) in Antwerp, Belgium. Between September 1999 and March 2004, 129 MSW were reached by Gh@pro, an outreach programme providing pre...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/095646205774763072
更新日期:2005-11-01 00:00:00
abstract::The aim of this work was to study the human papillomavirus (HPV) type-distribution in condylomata acuminata (CA) of mainland China and to estimate the potential role of HPV prophylactic vaccines for CA in mainland China. Forty-three studies using polymerase chain reaction to detect HPV were included in this meta-analy...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章,meta分析
doi:10.1258/ijsa.2008.008040
更新日期:2008-10-01 00:00:00
abstract::The primary aim of the current study was to test the effect of the presentation design of a test alert system on healthcare workers' (HCWs') decision-making regarding blood-borne virus (BBV) testing. The secondary aim was to determine HCWs' acceptance of the system. An online survey used a within-subjects research des...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/0956462420906998
更新日期:2020-07-01 00:00:00