A qualitative assessment of perspectives on the inclusion of adolescents in HIV vaccine trials in South Africa.

Abstract:

:Adolescents are at high risk for HIV acquisition, and thus need to be included in HIV vaccine trials. In preparation for inclusion of adolescents in HIV vaccine trials in an urban community in Cape Town with a high antenatal HIV prevalence, the study assessed the attitudes towards the inclusion of adolescents in HIV vaccine trials. A total of 18 focus group discussions were conducted using a semistructured interview guide. The participants (n = 200) were adolescents, young adults, parents and other key informants. Participants from all groups welcomed the inclusion of adolescents in HIV vaccine trials due to their high-risk status. There were, however, concerns about sexual disinhibition, fear of side-effects, fear of HIV testing and disclosure of HIV status, mistrust of nurses and clinics. The study highlighted a number of ethical and social issues that need to be addressed before the trials.

journal_name

Int J STD AIDS

authors

Jaspan HB,Soka NF,Mathews C,Flisher AJ,Mark D,Middelkoop K,Wood R,Bekker LG

doi

10.1258/ijsa.2009.008484

subject

Has Abstract

pub_date

2010-03-01 00:00:00

pages

172-6

issue

3

eissn

0956-4624

issn

1758-1052

pii

21/3/172

journal_volume

21

pub_type

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