Abstract:
:The transition of clinical trial data to changes in routine clinical practice is often a slow process. We describe a rapid transition of patients from one form of antiviral therapy to a modified and potentially safer version that can occur quickly when there are no financial or organisational restrictions on the prescribers.
journal_name
Int J STD AIDSjournal_title
International journal of STD & AIDSauthors
Smith DE,Tom M,Bowden BHdoi
10.1177/0956462418761260subject
Has Abstractpub_date
2018-09-01 00:00:00pages
1011-1013issue
10eissn
0956-4624issn
1758-1052journal_volume
29pub_type
杂志文章abstract::During the mid-1980s Australia experienced a remarkable decline in HIV incidence that can rightly be considered a public health milestone of global importance. The effects of this decline lasted for about 20 years and greatly benefited all Australians. In contrast, as we enter the mid-2000s, we see the global epidemic...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章,评审
doi:10.1258/095646206779307612
更新日期:2006-12-01 00:00:00
abstract::The effects of seminal high-risk human papillomavirus (HPV) DNA were assessed on the quality of semen. Semen samples of 65 men participating in the ongoing Finnish HPV Family Study were collected. Semen analyses were done by the guidelines of the Nordic Association for Andrology. HPV DNA was detected by nested polymer...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/0956462042395122
更新日期:2004-11-01 00:00:00
abstract::The aim of this work was to study the human papillomavirus (HPV) type-distribution in condylomata acuminata (CA) of mainland China and to estimate the potential role of HPV prophylactic vaccines for CA in mainland China. Forty-three studies using polymerase chain reaction to detect HPV were included in this meta-analy...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章,meta分析
doi:10.1258/ijsa.2008.008040
更新日期:2008-10-01 00:00:00
abstract::For people immunosuppressed by human immunodeficiency virus (HIV), we expect an increase in cancer incidence similar to that documented in transplant patients. We examined the cancer spectrum in an HIV-infected cohort, specifically malignancies not currently associated with acquired immunodeficiency syndrome (AIDS), i...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/0956462991913574
更新日期:1999-12-01 00:00:00
abstract::Stavudine is a potent nucleoside analogue and a well-recognized component of highly active antiretroviral therapy. Clinical trials have shown stavudine to have a superior or at least comparable virological efficacy and immune reconstitution when compared with other nucleoside analogues. Studies have shown that the pre...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章,评审
doi:10.1258/095646203322491842
更新日期:2003-10-01 00:00:00
abstract::It is important to assess uptake of a new vaccine. The present survey estimated the uptake of the recently introduced human papillomavirus vaccine (HPVV) in the emirate of Abu Dhabi and also explored barriers to uptake. A questionnaire survey was conducted in secondary schools, enrolling 334 girls. The uptake percenta...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/ijsa.2009.009380
更新日期:2011-07-01 00:00:00
abstract::Five hundred and twenty consecutive women newly attending a genitourinary medicine clinic who participated in a study of sexual behaviour were also tested for type-specific antibody to herpes simplex virus type 2; 135 (26%) were seropositive, of whom only 29 (21.5%) had had clinical evidence of genital herpes. Seropos...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/095646203321043237
更新日期:2003-01-01 00:00:00
abstract::Neisseria gonorrhoeae isolates that were resistant to ciprofloxacin and/or penicillin were analysed to investigate the escalating problem of antibiotic-resistant gonorrhoea in the north east of England. Opa-typing (outer membrane opacity protein) was carried out on isolates resistant to ciprofloxacin and of nutrient n...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/095646202321020044
更新日期:2002-12-01 00:00:00
abstract::HIV seroconversions and sexually transmitted diseases (STDs) are often clustered in social networks within community populations. The present study was carried out among men who have sex with men in Russia, where a major HIV epidemic is unfolding, and where social networks have played a historically important role. In...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/095646206775220504
更新日期:2006-01-01 00:00:00
abstract::The efficacy of oral azithromycin (500 mg daily for 10 days or 500 mg on alternate days for 11 days) in 100 patients with seropositive syphilis was studied. Clinical manifestations regressed more rapidly in azithromycin-treated patients compared with patients who received erythromycin or penicillin, and there was also...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/0956462961917249
更新日期:1996-01-01 00:00:00
abstract::Despite many reports of HIV-infected African children who have HIV-uninfected mothers, little is known about the extent and modes of horizontal HIV transmission in African children. We estimated the extent of horizontal HIV transmission in Swazi children by comparing child and mother HIV statuses in the 2006-2007 Swaz...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/ijsa.2009.009204
更新日期:2009-12-01 00:00:00
abstract::The aims of this study were to understand the prevalence and correlates of syphilis infection among HIV-positive men who have sex with men (MSM) in Shanghai, China. A total of 200 HIV-positive MSM participants were recruited using "snowball" sampling. Participants were tested for syphilis and completed a one-time ques...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/0956462413512804
更新日期:2014-05-01 00:00:00
abstract::The aim of this study was to investigate the prevalence of HIV infection in drug addicts and to address their drug habit, sexual life style and socioeconomic factors. This study was conducted among 505 male drug addicts comprising 250 intravenous drug users (IDUs) and 255 non-IDUs. Enzyme-linked immunosorbent assay wa...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/09564620360719813
更新日期:2003-11-01 00:00:00
abstract::We aim to assess the prevalence of HIV sexual risk behaviours and substance use among runaway and homeless adolescents in San Francisco, Denver and New York City. Survey data were examined from 775 runaway and homeless adolescents recruited from street settings and youth agencies during 1992/1993. Nearly all (98%) rep...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/0956462971919651
更新日期:1997-02-01 00:00:00
abstract::In Latin America, men who have sex with men (MSM) remain disproportionately impacted by HIV. Pre-exposure prophylaxis (PrEP) is an effective HIV prevention tool and has been FDA approved in the United States since 2012, but no Latin American state, with the recent exception of Brazil, has implemented PrEP guidelines. ...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/0956462419825944
更新日期:2019-05-01 00:00:00
abstract::The blood-taking practices and prevalence of needle-stick injuries were recorded for 46 house officers working at the two largest teaching hospitals in Sheffield and 38 house officers working at three hospitals in London. Wearing gloves when performing venesection or inserting an intravenous cannula was generally perc...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/095646249100200109
更新日期:1991-01-01 00:00:00
abstract::We aim to clarify the prevalence of Mycoplasma genitalium in asymptomatic men in Japan. First-catch urine specimens were obtained from 187 asymptomatic Japanese men and examined for the presence of M. genitalium using a polymerase chain reaction (PCR)-based assay. Two (1.1%) of 187 first-catch urine specimens were pos...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/0956462971919877
更新日期:1997-04-01 00:00:00
abstract::Cutaneous Candida infections may occur in patients with HIV/AIDS, cancer, receiving chemotherapy and solid organ transplantation. A 32-year-old woman was admitted to the department suffering from pruritic and erythematous plaque on left side of her face for the past two months. The patient was HIV positive, diagnosed ...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/0956462413479897
更新日期:2013-09-01 00:00:00
abstract::Routinely collected data from clinical sites offering voluntary counselling and testing (VCT) for HIV diagnosis have been used to evaluate the impact of public health interventions; however, there has been considerable diversity in strategies. To gain an understanding of the outcome of these evaluations and provide th...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章,评审
doi:10.1258/ijsa.2009.009005
更新日期:2009-06-01 00:00:00
abstract::A single-blind randomized follow-up study was conducted to evaluate the efficacy and tolerance of roxithromycin 300 mg once a day compared to doxycycline 200 mg day 1 and 100 mg day 2-10 in the treatment of genital chlamydial infection in men and women and non-specific urethritis (NSU) in men. A total of 211 patients ...
journal_title:International journal of STD & AIDS
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1177/095646249300400211
更新日期:1993-03-01 00:00:00
abstract::We describe a case of cryptococcal meningitis in a patient known to have HIV who presented initially with ocular cryptococcosis. This case highlights to clinicians the need to be aware of this association and to carry out relevant investigations so as to treat these patients appropriately. ...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/ijsa.2009.009132
更新日期:2012-05-01 00:00:00
abstract::Gonorrhoea in the UK is now a highly focal problem that is localized to certain inner city areas where it presents a significant public health concern. However, the majority of men and a proportion of women infested with Neisseria gonorrhoeae do not experience symptoms of sufficient intensity to prompt them to seek me...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/0956462981922539
更新日期:1998-08-01 00:00:00
abstract::Female entertainment and sex workers (FESW) have high rates of alcohol and amphetamine-type stimulant (ATS) use, increasing risk for HIV/sexually transmitted infections (STI), and other negative outcomes. A prospective cohort of 1,198 FESW in a HIV/ATS use prevention intervention in Cambodia was assessed for alcohol a...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/0956462420964647
更新日期:2020-12-13 00:00:00
abstract::We evaluated Cobas Amplicor, a highly automated polymerase chain reaction (PCR) system, to test first-void urine (FVU) and urethral swab specimens for Chlamydia trachomatis and Neisseria gonorrhoeae in men attending a sexually transmitted infection (STI) clinic. Results were compared against an in-house radioimmune do...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/0956462981921594
更新日期:1998-01-01 00:00:00
abstract::In this study 1155 injection drug users (IDUs) receiving targeted intervention in five cities of Punjab were surveyed; three cities (Amritsar, Taran-Taran, Batala) were in districts sharing an international border with Pakistan and the other two were Jalandhar and Ludhiana. Information on socio-demography, substance u...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/0956462413515659
更新日期:2014-07-01 00:00:00
abstract::Late HIV diagnosis in the UK remains a major cause of morbidity and mortality. In line with British HIV Association recommendations, we implemented routine HIV Screening in Croydon University Hospital Acute Medical Unit in London after an audit in 2011 revealed very high levels of late diagnosis. Our re-audit assessed...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/0956462415597346
更新日期:2016-06-01 00:00:00
abstract::A review of published and unpublished data indicates the prevalence of high-risk behaviours for HIV transmission in segments of the Bangladeshi population. These include casual unprotected sex, heterosexual as well as between males, prior to and after marriage. Intravenous drug use (IVDU) exists though illicit drugs a...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/0956462991913862
更新日期:1999-03-01 00:00:00
abstract::We assessed if gender and ethnicity were associated with differences in the number of patients satisfactorily treated and number of partners successfully treated for genital gonococcal infection by reviewing 400 cases. There were no differences in the rates of satisfactory treatment of gonorrhoea between men and women...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/0956462053654159
更新日期:2005-04-01 00:00:00
abstract::We determined the retention rate of patients infected with HIV who resumed care after being tracked at the Infectious Diseases Clinic (IDC) in Kampala, Uganda. Between April 2011 and September 2013, patients who missed their clinic appointment for 8-90 days were tracked, and those who returned to the clinic within 120...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/0956462414529098
更新日期:2015-01-01 00:00:00
abstract::Pubic hair grooming is common in many countries, but little is known about this practice in Africa. Grooming has been positively associated with self-reported sexually transmitted infections (STIs). This study aimed to investigate the prevalence and safety of pubic hair grooming in two South African settings. In KwaZu...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/0956462420941709
更新日期:2020-10-01 00:00:00