Abstract:
:Neisseria gonorrhoeae isolates that were resistant to ciprofloxacin and/or penicillin were analysed to investigate the escalating problem of antibiotic-resistant gonorrhoea in the north east of England. Opa-typing (outer membrane opacity protein) was carried out on isolates resistant to ciprofloxacin and of nutrient nonrequiring (NR) auxotype. In the year 2000 there were 265 cases of gonorrhoea, of which 44 (16.6%) were resistant to penicillin and 12 (4.5%) were resistant or had reduced sensitivity to ciprofloxacin (with only four of these acquired outside the UK). Three (7.5%) of the non-beta-lactamase penicillin-resistant isolates were imported from abroad. By Opa-typing of ciprofloxacin-resistant strains, one pair of the isolates was similar, two were unique and one was similar to the Oldham/Rochdale outbreak strain described early in 2000. This marked increase in the prevalence of indigenous ciprofloxacin resistance requires continued surveillance and may soon necessitate an alteration in our first line treatment.
journal_name
Int J STD AIDSjournal_title
International journal of STD & AIDSauthors
Elawad BB,Narayanan M,Pattman RS,Sankar KN,Freeman Rdoi
10.1258/095646202321020044subject
Has Abstractpub_date
2002-12-01 00:00:00pages
805-8issue
12eissn
0956-4624issn
1758-1052journal_volume
13pub_type
杂志文章abstract::In a study to determine the significance of Bacteroides ureolyticus in the lower urogenital tract using a new selective and differential medium, this organism was isolated from 30.1% of asymptomatic men, 37.8% of men with genital warts, and 26.3% of men with non-gonococcal urethritis. Using the same selective medium B...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/095646249200300206
更新日期:1992-03-01 00:00:00
abstract::Neisseria gonorrhoeae (GC) and Chlamydia trachomatis (CT) are two of the most prevalent bacterial sexually transmitted infections in the UK. Although the high burden of extra-genital infections with GC and CT in men who have sex with men has been well established, a significant number of extra-genital site infections ...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/0956462414543120
更新日期:2015-06-01 00:00:00
abstract::Risk factors for HIV infection in partners of HIV-seropositive index cases were investigated in a cross-sectional survey. Between September 1992 and April 1994 a total of 251 HIV-infected persons and 76 of their sexual partners were interviewed at the main sexually transmitted diseases (STDs) clinic in Trinidad. All p...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/0956462981921918
更新日期:1998-03-01 00:00:00
abstract::Influenza vaccination can reduce disease in HIV-infected children. The durability of the antibody response after trivalent influenza vaccine is important for management. The aim of this prospective study was to assess the durability of seroprotection for trivalent influenza vaccine strains and the factors effecting se...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/0956462415594061
更新日期:2016-08-01 00:00:00
abstract::Kaposi's sarcoma (KS) has a higher incidence in some parts of Africa than anywhere else in the world. Recent studies in western homosexual men with AIDS-KS suggest that KS may be caused by a putative sexually transmissible agent. Our analytical review of studies on KS in Africa before and during the AIDS era reveals a...
journal_title:International journal of STD & AIDS
pub_type: 社论,评审
doi:10.1258/0956462961917113
更新日期:1996-01-01 00:00:00
abstract::South Africa has a massive burden of HIV and alcohol disease, and these pandemics are inextricably linked. Much evidence indicates that alcohol independently influences decisions around sex, and undermines skills for condom negotiation and correct use. Thus, not surprisingly, people with problem drinking in Africa hav...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章,评审
doi:10.1258/ijsa.2000.009432
更新日期:2010-01-01 00:00:00
abstract::In 2010/2011, regional commissioners withdrew payment for the fixed-dose combination Combivir, forcing a switch to component drugs. This was deemed clinically acceptable and annual savings of £44 k expected. We estimated the true costs of switching and examined patient outcomes. Information for 46 patients using Combi...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/0956462414530588
更新日期:2015-02-01 00:00:00
abstract::The expense in time and money limit the use of randomized clinical trials (RCT) and cohort studies for evaluating long-term AIDS treatment outcomes. We conducted a case-control study to characterize predictors of AIDS mortality after the availability of highly active antiretroviral therapy (HAART) in San Francisco, in...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/ijsa.2008.008381
更新日期:2009-05-01 00:00:00
abstract::Gonorrhoea and chlamydia infections in women are often regarded as asymptomatic. Syndromic management of sexually transmitted disease (STDs), however, is partially based on vaginal symptoms. We sought to better identify STD-associated symptoms in women by development of composite genitourinary symptom constructs. Stan...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/0956462053057549
更新日期:2005-02-01 00:00:00
abstract::The blood-taking practices and prevalence of needle-stick injuries were recorded for 46 house officers working at the two largest teaching hospitals in Sheffield and 38 house officers working at three hospitals in London. Wearing gloves when performing venesection or inserting an intravenous cannula was generally perc...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/095646249100200109
更新日期:1991-01-01 00:00:00
abstract::During 2001 and 2002 an anonymous outreach-screening programme in Melbourne, Australia, offered testing for gonorrhoea and chlamydia on-site at men-only saunas. Modifications were made to this screening programme to offer a comprehensive testing clinic for sexually transmissible infections (STIs), including HIV. The c...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/095646205774988163
更新日期:2005-12-01 00:00:00
abstract::People tend to believe that their chance of experiencing undesirable events is lower and their chance of experiencing desirable events is higher than that of the average person like them. Two explanatory models of such 'unrealistic optimism' (UO) have been proposed: While the motivational account holds that UO serves ...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/095646206775809169
更新日期:2006-03-01 00:00:00
abstract::National guidelines state that hepatitis B and C testing should be targeted to those with risk factors. However, there is little data to support this recommendation. There is also limited data of viral hepatitis prevalence in attendees at genitourinary medicine clinics. We report the prevalence of hepatitis B infectio...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/0956462416641528
更新日期:2017-03-01 00:00:00
abstract::The effects of seminal high-risk human papillomavirus (HPV) DNA were assessed on the quality of semen. Semen samples of 65 men participating in the ongoing Finnish HPV Family Study were collected. Semen analyses were done by the guidelines of the Nordic Association for Andrology. HPV DNA was detected by nested polymer...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/0956462042395122
更新日期:2004-11-01 00:00:00
abstract::In this structured review, we evaluated purulent vaginal and cervical discharge as diagnostic tests for pelvic inflammatory disease (PID). Using a pretest probability of PID (diagnosed clinically) of 50%, we used the odds-likelihood formulation of Bayes' theorem to calculate post-test probabilities of PID (proven by l...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章,评审
doi:10.1258/ijsa.2008.008261
更新日期:2009-02-01 00:00:00
abstract::Raltegravir is one of the standard antiretroviral therapy (ART) options in treatment-experienced and -naïve patients. However, efficacy data from clinical practice are scarce. Therefore, the efficacy of raltegravir-containing ART in clinical practice was investigated retrospectively. In all, 295 treatment-naïve and -e...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/0956462415610678
更新日期:2016-11-01 00:00:00
abstract::There is a need for new hypotheses to supplement existing explanations for the observed differences in HIV prevalence between countries and within countries. Due to high levels of viraemia during the initial phase of HIV infection, networks of concurrent regular partnerships in a community could be the determining fac...
journal_title:International journal of STD & AIDS
pub_type: 社论
doi:10.1177/095646249300400501
更新日期:1993-09-01 00:00:00
abstract::The aim of this study was to investigate the factors relating to CD4 level at HIV diagnosis and HIV testing behaviour. Participants were newly diagnosed patients (n = 654) in Japan from 2000 to 2005. Around 75% of participants were diagnosed at hospital and clinics. Mean CD4 counts at diagnosis through voluntary HIV t...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/ijsa.2009.009493
更新日期:2012-04-01 00:00:00
abstract::This study aimed to describe the quality and costs of sexually transmitted disease (STD) case management in urban pharmacies in The Gambia, and explore pharmacy workers' (PWs) willingness to improve the STD care they provide. PWs from 24 registered pharmacies were interviewed in order to collect information on their k...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/0956462011923471
更新日期:2001-07-01 00:00:00
abstract::We conducted a literature review of patients' conditions described under persistent genital arousal disorder and restless genital syndrome, vulvodynia and male genital skin pain of unknown aetiology (penoscrotodynia). Our aim is to improve the understanding of the condition, unify nomenclature and promote evidence-bas...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章,评审
doi:10.1177/0956462413489276
更新日期:2013-11-01 00:00:00
abstract::We report a case of acute epididymo-orchitis due to early infectious syphilis, mimicking as testicular malignancy in an undiagnosed HIV-positive individual. He presented with a mass on his testicle and simultaneously had serology consistent with early syphilis. It could not be distinguished from a malignancy, which ne...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/ijsa.2008.008253
更新日期:2009-01-01 00:00:00
abstract::Rates of sexually transmitted infections (STI) in the UK continue to increase. A discrepancy between knowledge and awareness of STIs, and sexual behaviour appears to be ubiquitous throughout the world. We hypothesize that human beings are biologically programmed to fall in love and bond in powerful relationships, whic...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章,评审
doi:10.1258/0956462054944435
更新日期:2005-09-01 00:00:00
abstract::A retrospective casenote study was conducted to examine the risk factors for patients who were diagnosed as hepatitis C (HCV)-positive (between 1999 and 2001) in a semi-rural genitourinary medicine (GUM) setting in Staffordshire, UK. There was a remarkable escalation in the number of reported HCV-positive cases, year ...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/095646202321020143
更新日期:2002-12-01 00:00:00
abstract::Post-exposure prophylaxis (PEP) is a promising but under-utilized strategy for HIV prevention in high-risk populations. Between March 2010 and June 2011, two community-based clinics in Los Angeles County provided PEP in a pilot program to 267 unique individuals. Courses were primarily dispensed to men who have sex wit...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/0956462417743158
更新日期:2018-05-01 00:00:00
abstract::Ninety women who were HIV antibody positive attended the genitourinary medicine clinics of East Riverside up to May 1990. Seventy-five of these women (83%) were examined for co-existent sexually transmitted disease (STD) at presentation. The prevalence of STD in these women was compared to the incidence of STD in all ...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/095646249100200312
更新日期:1991-05-01 00:00:00
abstract::In 1987, data from the Centers for Disease Control AIDS data base indicated a 50% prevalence of oropharyngeal Candida infection, a 10% rate of esophageal infection, and .5% rate of bronchopulmonary infection among AIDS patients. Candida-positive blood cultures were found in 13 of 903 AIDS patients, and disseminated C...
journal_title:International journal of STD & AIDS
pub_type: 社论
doi:10.1177/095646249200300301
更新日期:1992-05-01 00:00:00
abstract::This study sought to determine IgA, IgG antibodies to Candida albicans in whole saliva and serum from HIV-infected patients and to compare them to a group of healthy controls. The study population consisted of 34 HIV-infected individuals free of any other systemic diseases and thirty healthy controls. IgA concentratio...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/095646202760029787
更新日期:2002-06-01 00:00:00
abstract::This paper describes the incidence of sexually transmitted infections (STIs) recorded in the Weekly Returns Service (WRS) between 1994 and 2001. There were approximately 76,500 new diagnoses of STIs (7500 males, 71,000 females) and associated syndromes. Candidiasis was the commonest condition reported in males and fem...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/095646206780070992
更新日期:2006-10-01 00:00:00
abstract::This study employed culture and polymerase chain reaction (PCR) to examine the prevalence of Ureaplasma urealyticum, Mycoplasma hominis, Mycoplasma genitalium, Mycoplasma fermentans, Mycoplasma penetrans and Mycoplasma pirum in 210 HIV/AIDS patients, 455 sexually transmitted infection (STI) clinic attendees and 245 he...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/ijsa.2009.009396
更新日期:2012-08-01 00:00:00
abstract::Few studies investigate sexual health among Chinese international students in Australia. We recruited domestic (n = 623) and Chinese international (n = 500) students for separate online surveys on sexual behaviours and knowledge. Samples were compared using Chi square, Fisher's exact and equality of medians tests. Dom...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/0956462420921726
更新日期:2020-07-01 00:00:00