Abstract：
:We evaluated Cobas Amplicor, a highly automated polymerase chain reaction (PCR) system, to test first-void urine (FVU) and urethral swab specimens for Chlamydia trachomatis and Neisseria gonorrhoeae in men attending a sexually transmitted infection (STI) clinic. Results were compared against an in-house radioimmune dot blot (DB) test for C. trachomatis and selective culture for N. gonorrhoeae. Three hundred and ninety sets of specimens were obtained from 378 consecutive new and returned-new patients. Gonorrhoea prevalence was 9.49%, with no significant difference in sensitivity or specificity between culture and PCR. Chlamydia prevalence was 15.4%, with sensitivities of: DB 55%, PCR of FVU 86.7%, urethral swab PCR 90%. The specificity of PCR on FVU and urethral swabs was 100%. We have shown that Cobas Amplicor PCR is highly sensitive and specific in the diagnosis of chlamydia and gonorrhoea in men attending an STI clinic. Further economic and scientific studies are needed to determine the cost-effectiveness of this technique for screening in primary care settings.
journal_name
Int J STD AIDSjournal_title
International journal of STD & AIDSauthors
Higgins SP,Klapper PE,Struthers JK,Bailey AS,Gough AP,Moore R,Corbitt G,Bhattacharyya MNdoi
10.1258/0956462981921594subject
Has Abstractpub_date
1998-01-01 00:00:00pages
21-4issue
1eissn
0956-4624issn
1758-1052journal_volume
9pub_type
杂志文章abstract：:The objective of the study was to determine the association of neurocognitive impairment with health-related quality of life (HRQoL) in patients receiving highly active antiretroviral therapy (HAART). Seventy subjects were cross-sectionally analysed with a standardized neuropsychological test battery and a questionnai...
journal_title：International journal of STD & AIDS
pub_type： 杂志文章
doi：10.1258/095646204773557794
更新日期：2004-04-01 00:00:00
abstract：:Over the Christmas and New Year period the Health Education Authority launched a sexual health promotion campaign aimed at increasing the awareness of and reducing the incidence of sexually transmitted infections (STIs) and unwanted pregnancy. We undertook a study to assess the effect of this campaign locally in 2 gen...
journal_title：International journal of STD & AIDS
pub_type： 杂志文章
doi：10.1258/0956462001916560
更新日期：2000-09-01 00:00:00
abstract：:These clinical standards for the screening and management of acquired syphilis in HIV-positive patients in the UK were first made available on the MSSVD website in February 2002. They have been updated by the 2006 UK National Guideline on the Sexual Health of People with HIV which is also published in this issue of th...
journal_title：International journal of STD & AIDS
pub_type： 指南,杂志文章
doi：10.1258/095646206778113096
更新日期：2006-09-01 00:00:00
abstract：:The sensitivity of the Captia Syphilis G anti-treponemal IgG enzyme immunoassay (EIA-IgG) was compared with the Treponema pallidum haemagglutination assay (TPHA) and the Fluorescent Treponemal Antibody Absorbed (FTA-Abs) test as a marker for past syphilis in 28 HIV-infected and 31 HIV-negative patients with a past his...
journal_title：International journal of STD & AIDS
pub_type： 杂志文章
doi：10.1177/095646249500600207
更新日期：1995-03-01 00:00:00
abstract：:Seventy-eight men with symptoms of chronic or subacute prostatitis were enrolled. Investigations for the presence of Chlamydia trachomatis in urethral swabs were carried out. The expressed prostatic secretions were additionally examined for Mycoplasma hominis, Ureaplasma urealyticum, Gardnerella vaginalis, other gram-...
journal_title：International journal of STD & AIDS
pub_type： 杂志文章
doi：10.1258/0956462981922395
更新日期：1998-06-01 00:00:00
abstract：:Pneumocystis jirovecii pneumonia (PCP) prophylaxis may be discontinued when CD4 is > or =200 cells/mm(3) for three months in response to highly active antiretroviral therapy (HAART). Unlike CD4, the total lymphocyte count (TLC) is inexpensive and widely available in resource-constrained countries. Paired TLC and CD4 v...
journal_title：International journal of STD & AIDS
pub_type： 杂志文章
doi：10.1258/ijsa.2009.009090
更新日期：2010-06-01 00:00:00
abstract：:A 32-year-old HIV-infected woman developed fever and systemic illness of unknown origin after being placed on phenytoin for seizures. Her clinical syndrome, skin biopsy findings, and clinical response to steroids were consistent with phenytoin hypersensitivity syndrome. ...
journal_title：International journal of STD & AIDS
pub_type： 杂志文章
doi：10.1258/0956462053057648
更新日期：2005-02-01 00:00:00
abstract：:It is important to assess uptake of a new vaccine. The present survey estimated the uptake of the recently introduced human papillomavirus vaccine (HPVV) in the emirate of Abu Dhabi and also explored barriers to uptake. A questionnaire survey was conducted in secondary schools, enrolling 334 girls. The uptake percenta...
journal_title：International journal of STD & AIDS
pub_type： 杂志文章
doi：10.1258/ijsa.2009.009380
更新日期：2011-07-01 00:00:00
abstract：:A single-blind randomized follow-up study was conducted to evaluate the efficacy and tolerance of roxithromycin 300 mg once a day compared to doxycycline 200 mg day 1 and 100 mg day 2-10 in the treatment of genital chlamydial infection in men and women and non-specific urethritis (NSU) in men. A total of 211 patients ...
journal_title：International journal of STD & AIDS
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1177/095646249300400211
更新日期：1993-03-01 00:00:00
abstract：:In Bambari and Bria, 2 towns in the Central African Republic (CAR), we analysed a patient-led partner referral programme within enhanced sexually transmitted disease (STD) services. New (index) patients received syndromic management, counselling about notifying and treating contacts, and vouchers for distribution. Fro...
journal_title：International journal of STD & AIDS
pub_type： 杂志文章
doi：
更新日期：1999-06-01 00:00:00
abstract：:We assessed if gender and ethnicity were associated with differences in the number of patients satisfactorily treated and number of partners successfully treated for genital gonococcal infection by reviewing 400 cases. There were no differences in the rates of satisfactory treatment of gonorrhoea between men and women...
journal_title：International journal of STD & AIDS
pub_type： 杂志文章
doi：10.1258/0956462053654159
更新日期：2005-04-01 00:00:00
abstract：:We adapted the Healthy Love Workshop (HLW), an HIV prevention workshop for African American women in the United States, for African, Caribbean and Black (ACB) women in Toronto, Canada. We conducted a pilot study with ACB women ( n = 80) in ten community-based settings with pre-test (T1), post-test (T2) and three-month...
journal_title：International journal of STD & AIDS
pub_type： 杂志文章
doi：10.1177/0956462418754971
更新日期：2018-07-01 00:00:00
abstract：:As few studies have compared the clinical features of rectal gonorrhoea in men who have sex with men with or without concurrent chlamydial infection, this longitudinal study was undertaken to address this issue. The cohort consisted of 129 men with rectal gonorrhoea, 34 of whom had concurrent chlamydiae. Symptoms of p...
journal_title：International journal of STD & AIDS
pub_type： 杂志文章
doi：10.1258/095646206777323373
更新日期：2006-06-01 00:00:00
abstract：:An HIV-positive African woman developed severe constitutional symptoms associated with rebound viraemia during a planned antiretroviral treatment interruption, requiring reinitiation of highly active antiretroviral therapy. ...
journal_title：International journal of STD & AIDS
pub_type： 杂志文章
doi：10.1258/0956462041558131
更新日期：2004-08-01 00:00:00
abstract：:The current cervical screening guidelines lay the duty of care of women under 25 years of age on genitourinary (GU) medicine clinics. To date there has not been an extensive review of cervical cytology results sourced from GU medicine departments. We reviewed the annual reports of the cervical screening programme, wit...
journal_title：International journal of STD & AIDS
pub_type： 杂志文章,评审
doi：10.1258/ijsa.2009.009122
更新日期：2009-10-01 00:00:00
abstract：:In a retrospective database study at two HIV treatment centres, medical records were accessed to evaluate long-term efficacy and safety parameters in all HIV-infected adults who had achieved HIV-1 RNA <50 copies/mL following the initiation of fosamprenavir (FPV)/ritonavir (RTV) 1400 mg/100 mg once-daily (QD)-containin...
journal_title：International journal of STD & AIDS
pub_type： 杂志文章
doi：10.1258/ijsa.2009.009161
更新日期：2012-03-01 00:00:00
abstract：SUMMARY:The objective of this study was to identify factors associated with (i) longer patient travel time to genitourinary (GU) medicine clinics and (ii) not attending the nearest clinic. Questionnaires were completed by 4600 new attendees from seven sociodemographically and geographically different GU clinics across ...
journal_title：International journal of STD & AIDS
pub_type： 杂志文章
doi：10.1258/ijsa.2008.008205
更新日期：2008-12-01 00:00:00
abstract：:There is still a paucity of research on the sociodemographic and other underlying factors associated with HIV transmission among women in India. This study was designed to investigate such factors in sexually experienced Indian women. We used data from the National Family Health Survey 3 (NFHS-3), which tested 52,853 ...
journal_title：International journal of STD & AIDS
pub_type： 杂志文章
doi：10.1258/ijsa.2010.010127
更新日期：2011-03-01 00:00:00
abstract：:We sought to analyse reasons for attendance of older women (defined as aged 46 years and over) to genitourinary (GU) medicine services at two UK clinics. We used KC60 coding data to count new episode attendances by year from 1998 to 2008 and to further dissect reason for attendance in 2827 new episodes during 2003-200...
journal_title：International journal of STD & AIDS
pub_type： 杂志文章
doi：10.1258/ijsa.2012.011426
更新日期：2012-08-01 00:00:00
abstract：:Measurement of HIV viral load (VL) is the best indicator of success of antiretroviral therapy. We investigated the correlation between results by the Cepheid GeneXpert and a standard of care VL assay (Abbott M2000). This was a prospective study of people living with HIV who attended the department for routine VL measu...
journal_title：International journal of STD & AIDS
pub_type： 杂志文章
doi：10.1177/0956462420975606
更新日期：2021-01-09 00:00:00
abstract：:Chlamydia trachomatis and Neisseria gonorrhoeae testing guidance recommends extragenital screening with locally validated nucleic acid amplification tests, with anatomical sites tested separately. Evidence supports multi-patient combined aliquot pooled sampling (PS) for population screening; evidence for within-patien...
journal_title：International journal of STD & AIDS
pub_type： 杂志文章
doi：10.1177/0956462417742318
更新日期：2018-05-01 00:00:00
abstract：:We describe a case of cryptococcal meningitis in a patient known to have HIV who presented initially with ocular cryptococcosis. This case highlights to clinicians the need to be aware of this association and to carry out relevant investigations so as to treat these patients appropriately. ...
journal_title：International journal of STD & AIDS
pub_type： 杂志文章
doi：10.1258/ijsa.2009.009132
更新日期：2012-05-01 00:00:00
abstract：:Hispanic and Black adults are disproportionately affected by HIV and experience poorer HIV-related health outcomes relative to non-Hispanic White adults. The current study adopted Sørensen's integrated model to test the hypothesis that lower functional and critical health literacy competencies contribute to poorer HIV...
journal_title：International journal of STD & AIDS
pub_type： 杂志文章
doi：10.1177/0956462417738679
更新日期：2018-04-01 00:00:00
abstract：:Australian and New South Wales Sexually Transmissible Infections Strategies recommend sexual health clinics actively target particular populations, including men who have sex with men (MSM), who have increasing rates of sexually transmitted infections (STIs). We describe trends in MSM attendances, STI testing and diag...
journal_title：International journal of STD & AIDS
pub_type： 杂志文章
doi：10.1258/ijsa.2010.010458
更新日期：2011-06-01 00:00:00
abstract：:Sexually transmitted infections (STIs) in Vietnam have been increasing. Control of STIs among female sex workers (FSWs) is important in controlling the epidemic. Effective STI control requires that physicians are skilful in taking sexual history for FSW patients. Three hundred and seventy-one physicians responded to a...
journal_title：International journal of STD & AIDS
pub_type： 杂志文章
doi：10.1177/0956462414529553
更新日期：2015-01-01 00:00:00
abstract：:Antiretroviral treatment roll-out programmes in Africa often have difficulties to cope with the increasing number of clients. Based on the findings of a survey carried out in 2005 that showed long waiting times, innovative organizational changes (nurse visits and pharmacy-only refill visits) were introduced in our cli...
journal_title：International journal of STD & AIDS
pub_type： 杂志文章
doi：10.1258/ijsa.2008.008174
更新日期：2009-02-01 00:00:00
abstract：:The purpose of this paper is to assess the internal consistency of self-reported condom use among sex workers in Puerto Plata and Santo Domingo, Dominican Republic. We examined the responses to questions about condom use among 4 cross-sectional samples of sex workers. We compared measures based on: (1) questions using...
journal_title：International journal of STD & AIDS
pub_type： 杂志文章
doi：10.1258/0956462981922089
更新日期：1998-04-01 00:00:00
abstract：:Our objectives were to determine the prevalence of Neisseria gonorrhoeae and its association with other STD causing organisms. Three hundred and thirty-six consecutive women (female sex workers (FSWs) and married contacts), attending a sexually transmitted disease (STD) clinic in Mumbai, were screened for N. gonorrhoe...
journal_title：International journal of STD & AIDS
pub_type： 杂志文章
doi：10.1258/0956462001914896
更新日期：2000-01-01 00:00:00
abstract：:The prevalence of viral and bacterial sexually transmitted diseases were studied in 101 men attending a dermatovenereal outpatient clinic in Mogadishu. A control group of 103 healthy adult men were included for the serological part of the study. Serological markers of hepatitis B virus (HBV), human immunodeficiency vi...
journal_title：International journal of STD & AIDS
pub_type： 杂志文章
doi：10.1177/095646249000100206
更新日期：1990-03-01 00:00:00
abstract：:We retrospectively analysed routinely collected baseline data of 2252 patients with HIV infection registered in the National Free Antiretroviral Treatment Program in Xinjiang province, China, from 2006 to 2011 to estimate the prevalence and predictors of anaemia at the initiation of combined antiretroviral therapy. An...
journal_title：International journal of STD & AIDS
pub_type： 杂志文章
doi：10.1177/0956462414531935
更新日期：2015-03-01 00:00:00
