Abstract：
:Chlamydia trachomatis and Neisseria gonorrhoeae testing guidance recommends extragenital screening with locally validated nucleic acid amplification tests, with anatomical sites tested separately. Evidence supports multi-patient combined aliquot pooled sampling (PS) for population screening; evidence for within-patient PS is sparse. Within-patient PS could be more cost-effective for triple-site testing, but requires distinct clinical pathways and consideration over loss of information to guide risk assessments and treatment. We explored PS attitudes and practices amongst clinicians in England. A cross-sectional web-based survey was distributed to clinical leads of sexual health services throughout England in February 2016. Fifty-two (52/216, 23%) services responded. One service reported current within-patient PS and two were awaiting implementation. Of the 49 services not pooling, five were considering implementation. Concerns raised included the inability to distinguish infection site(s) (36/52, 69%), absence of national guidance (34/52, 65%) and reduced assay performance (18/52, 34%). Only 8/52 (15%) considered the current level of evidence sufficient to support PS, with 40/52 (77%) requesting further validation studies and 39/52 (77%) national guidance. PS was rarely used by respondents to this survey, although the response rate was low. The clinical challenges presented by PS need to be addressed through further development of the evidence base.
journal_name
Int J STD AIDSjournal_title
International journal of STD & AIDSauthors
Shaw J,Saunders JM,Hughes Gdoi
10.1177/0956462417742318subject
Has Abstractpub_date
2018-05-01 00:00:00pages
547-551issue
6eissn
0956-4624issn
1758-1052journal_volume
29pub_type
杂志文章abstract：:This study examined some characteristics of male clinic attenders with urethral chlamydial infection. The prevalence of urethral chlamydial infection among heterosexual men (men who have sex with women [MSW]) was 446 (17%) of 2684 men. Men aged 16-34 years were more likely to have chlamydiae than older men with only c...
journal_title：International journal of STD & AIDS
pub_type： 杂志文章
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journal_title：International journal of STD & AIDS
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journal_title：International journal of STD & AIDS
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journal_title：International journal of STD & AIDS
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journal_title：International journal of STD & AIDS
pub_type： 杂志文章
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pub_type： 杂志文章
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journal_title：International journal of STD & AIDS
pub_type： 杂志文章
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更新日期：2008-03-01 00:00:00
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journal_title：International journal of STD & AIDS
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更新日期：2002-11-01 00:00:00
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journal_title：International journal of STD & AIDS
pub_type： 杂志文章
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更新日期：2014-10-01 00:00:00
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journal_title：International journal of STD & AIDS
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journal_title：International journal of STD & AIDS
pub_type： 杂志文章
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journal_title：International journal of STD & AIDS
pub_type： 杂志文章,meta分析,评审
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更新日期：2015-04-01 00:00:00
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journal_title：International journal of STD & AIDS
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更新日期：2005-04-01 00:00:00
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journal_title：International journal of STD & AIDS
pub_type： 杂志文章
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更新日期：2010-08-01 00:00:00
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journal_title：International journal of STD & AIDS
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journal_title：International journal of STD & AIDS
pub_type： 杂志文章
doi：
更新日期：1999-06-01 00:00:00
